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| Pfizer recalls more Lipitor over odors NEW YORK (UPI) -- Pfizer is recalling yet more Lipitor shipments over reports of unpleasant odors, the drug company said.
The New York company announced Friday a recall of about 38,000 bottles of 40-milligram tablets distributed in the United States, The Wall Street Journal reported. Pfizer recalled about 332,000 bottles of the cholesterol-lowering medicine in August.
The company linked the uncharacteristic smell to the bottles, which it said were supplied by an outside manufacturer in Puerto Rico.
Pfizer warned there may be more recalls because products made before production procedures were fixed could still be on the market.
The company said Friday the odor is consistent with the presence of 2,4,6 tribromoanisole, or TBA, which was found at a very low level in a sample bottle during the probe that led to the first recall. TBA is used as a wood preservative on pallets.
Pfizer spokesman Ray Kerins said the company has taken steps to cut risk of TBA contamination, including requiring the use of plastic pallets to transport empty bottles.
Lipitor is the best-selling prescription drug in the world.
Copyright 2010 by United Press International |
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| Brain circuitry, PSTD flashback link MINNEAPOLIS (UPI) -- U.S. researchers have linked increased activity in the right side of the brain to flashbacks related to post-traumatic stress disorder.
Flashbacks -- the re-living of past experiences -- and/or recurring nightmares, anger or hyper-vigilance mark the disorder that can follow any psychologically traumatic event.
Researchers at the University of Minnesota in Minneapolis used a non-invasive measurement of the brain's magnetic fields called magnetoencephalography to identify flashbacks linked to a hyperactive brain network.
The researchers found differences between signals in the temporal and parieto-occipital right hemispheric areas of the brain that other types of brain scans -- such as X-ray or magnetic resonance imaging -- have not shown. In those with PTSD, the temporal cortex is thought to be responsible for the re-living of past experience, the researchers say.
The study, published in the Journal of Neural Engineering, finds a clear difference in activity among the circuitry in the brains of PTSD sufferers versus those without the condition.
"Having a diagnostic exam capable of confirming post-traumatic stress disorder is critical in treating these patients properly," Dr. Apostolos Georgopoulos, the study leader, said in a statement.
Copyright 2010 by United Press International |
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| High deductibles can delay healthcare LOS ANGELES (UPI) -- Californians who have health insurance plans with high-deductibles -- more than $1,000 -- may delay care or risk financial jeopardy, researchers say.
A report from the Center for Health Policy Research at the University of California, Los Angeles, says 3 million Californians in 2007 were enrolled in high-deductible health plans, many of them self-employed or poor who often cannot afford the deductible and put off healthcare.
Lead author Dylan Roby says high-deductible plans are defined as those that have out-of-pocket deductibles of $1,000 or more for individuals or $2,000 or more for families, some which can exceed $5,000 annually.
"Many Californians can't afford higher-premium plans, especially in the current economic climate," Roby says in a statement. "But the alternative -- high-deductible plans -- may cost less initially but can cost thousands of dollars when you need healthcare."
The study also says the vast majority of members in high-deductible health plans had no health savings account that might help mitigate the cost of the deductibles or out-of-pocket expenses.
Roby says healthcare reform -- The Affordable Care Act -- which help these families because the California Health Benefits Exchange will provide more robust insurance as part of national healthcare reform, while capping out-of-pocket deductibles at $2,000 for individuals and $4,000 for families, and offering subsidies for those with low incomes.
Copyright 2010 by United Press International |
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| New device may reveal brain injury secrets LONDON (UPI) -- British researchers are probing the puzzling second wave of damage -- days after the initial injury -- found in some head injury patients.
About 1 million people with head injuries annually in United States experience a mysterious second round of brain damage days after the initial injury, just as they appear to be recovering.
Limited clinical trials are in progress using a new monitoring device capable of second-by-second monitoring of brain chemistry, the researchers say.
The device -- developed at the Imperial College London -- uses the "microfluidic method" to measure glucose quickly as an indicator of activity in fractions of a second.
Brain activity decreases in patients following initial trauma with chemical changes spreading from the injury site and knocking out nerve cells -- what researchers call depolarization. It takes large amounts of glucose to reactivate the cells, so monitoring glucose levels can help doctors tell whether or not a patient is taking a turn for the worse, the researchers say.
The new device also is being tested on patients who have suffered trauma, stroke or aneurysm, the researchers say.
The study is published in Chemical & Engineering News.
Copyright 2010 by United Press International |
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| Get Ready for Thanksgiving Start planning for Thanksgiving well in advance, and make sure you're ready for the big day when it rolls around! Learn how to host a Thanksgiving party, try out some new stuffing recipes, or -- if you're feeling especially daring -- have a go at deep-frying your turkey this year!
Helpful tips, recipes, and more are available fee from the ArcaMax Thanksgiving Feature, as well as trivia, interactive quizzes, and books to sample free from BookDaily.
-- From the ArcaMax editors |
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