Acta Pharmacologica Sinica - Table of Contents alert Volume 38 Issue 2

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Acta Pharmacologica Sinica

Volume 38, Issue 2 (February 2017)

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Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system OPEN

Kun Zou, Zhao Li, Yong Zhang, Hao-yue Zhang, Bo Li, Wei-liang Zhu, Ji-ye Shi, Qi Jia and Yi-ming Li

Acta Pharmacol Sin 2017 38: 157-167; advance online publication, December 5, 2016; 10.1038/aps.2016.125

Abstract | Full Text

Original Articles


SIRT1 plays a neuroprotective role in traumatic brain injury in rats via inhibiting the p38 MAPK pathway

Hong Yang, Zheng-tao Gu, Li Li, Mac Maegele, Bi-ying Zhou, Feng Li, Ming Zhao and Ke-sen Zhao

Acta Pharmacol Sin 2017 38: 168-181; advance online publication, December 26, 2016; 10.1038/aps.2016.130

Abstract | Full Text

Resveratrol rescues hyperglycemia-induced endothelial dysfunction via activation of Akt

Jin-yi Li, Wei-qiang Huang, Rong-hui Tu, Guo-qiang Zhong, Bei-bei Luo and Yan He

Acta Pharmacol Sin 2017 38: 182-191; advance online publication, December 12, 2016; 10.1038/aps.2016.109

Abstract | Full Text

Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression

Qi Huang, Ting Wang and He-yao Wang

Acta Pharmacol Sin 2017 38: 192-200; advance online publication, December 26, 2016; 10.1038/aps.2016.135

Abstract | Full Text

Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice

Yong-qin Zhou, Xiu-fang Weng, Rui Dou, Xiao-sheng Tan, Tian-tian Zhang, Jin-bo Fang and Xiong-wen Wu

Acta Pharmacol Sin 2017 38: 201-210; advance online publication, October 31, 2016; 10.1038/aps.2016.102

Abstract | Full Text

Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway

Kang-feng Jiang, Gan Zhao, Gan-zhen Deng, Hai-chong Wu, Nan-nan Yin, Xiu-ying Chen, Chang-wei Qiu and Xiu-li Peng

Acta Pharmacol Sin 2017 38: 211-222; advance online publication, November 28, 2016; 10.1038/aps.2016.123

Abstract | Full Text

Dose-biomarker-response modeling of the anticancer effect of ethaselen in a human non-small cell lung cancer xenograft mouse model

Suo-fu Ye, Jian Li, Shuang-min Ji, Hui-hui Zeng and Wei Lu

Acta Pharmacol Sin 2017 38: 223-232; advance online publication, December 5, 2016; 10.1038/aps.2016.114

Abstract | Full Text

Efficacy of afatinib, an irreversible ErbB family blocker, in the treatment of intracerebral metastases of non-small cell lung cancer in mice

Shi-rong Zhang, Lu-cheng Zhu, Yan-ping Jiang, Jing Zhang, Ru-jun Xu, Ya-si Xu, Bing Xia and Sheng-lin Ma

Acta Pharmacol Sin 2017 38: 233-240; advance online publication, November 14, 2016; 10.1038/aps.2016.107

Abstract | Full Text

Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways

Da-xuan Wang, Yu-jiao Zou, Xi-bin Zhuang, Shu-xing Chen, Yong Lin, Wen-lan Li, Jun-jin Lin and Zhi-qiang Lin

Acta Pharmacol Sin 2017 38: 241-251; advance online publication, November 28, 2016; 10.1038/aps.2016.122

Abstract | Full Text

Oblongifolin C and guttiferone K extracted from Garcinia yunnanensis fruit synergistically induce apoptosis in human colorectal cancer cells in vitro

Hui Li, Xiao-xiao Meng, Li Zhang, Bao-jun Zhang, Xin-yu Liu, Wen-wei Fu, Hong-sheng Tan, Yuan-zhi Lao and Hong-xi Xu

Acta Pharmacol Sin 2017 38: 252-263; advance online publication, November 14, 2016; 10.1038/aps.2016.101

Abstract | Full Text

Shenmai injection enhances the cytotoxicity of chemotherapeutic drugs against colorectal cancers via improving their subcellular distribution

Wen-yue Liu, Jing-wei Zhang, Xue-quan Yao, Chao Jiang, Ji-chao He, Pin Ni, Jia-li Liu, Qian-ying Chen, Qing-ran Li, Xiao-jie Zang, Lan Yao, Ya-zhong Liu, Mu-lan Wang, Pei-qiang Shen, Guang-ji Wang and Fang Zhou

Acta Pharmacol Sin 2017 38: 264-276; advance online publication, November 21, 2016; 10.1038/aps.2016.99

Abstract | Full Text

Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro

Nan Zheng, Lu Liu, Wei-wei Liu, Fei Li, Toshihiko Hayashi, Shin-ichi Tashiro, Satoshi Onodera and Takashi Ikejima

Acta Pharmacol Sin 2017 38: 277-289; advance online publication, November 21, 2016; 10.1038/aps.2016.117

Abstract | Full Text

Delivery of acetylthevetin B, an antitumor cardiac glycoside, using polymeric micelles for enhanced therapeutic efficacy against lung cancer cells

Jing-jing Zhu, Xin-xin Zhang, Yun-qiu Miao, Shu-fang He, Dan-mei Tian, Xin-sheng Yao, Jin-shan Tang and Yong Gan

Acta Pharmacol Sin 2017 38: 290-300; advance online publication, December 5, 2016; 10.1038/aps.2016.113

Abstract | Full Text

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