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Stem cells: A new way to induce pluripotency Image: Haruko Obokata An unusual reprogramming phenomenon by which the fate of somatic cells can be drastically altered through changes to the external environment is described in two papers in this week’s Nature. Haruko Obokata and co-authors demonstrate that mammalian somatic cells can be reprogrammed when stressed by low-pH conditions, and call the phenomenon stimulus-triggered acquisition of pluripotency (STAP). In a second paper, Obokata and colleagues investigate the nature of STAP cells and suggest that they represent a unique state of pluripotency. The researchers also demonstrate that under pluripotent stem-cell culture conditions STAP cells can be transformed into robustly self-renewing stem cells, similar to embryonic stem cells. Access the related news article online. Click here to register for updates from Nature.   This offer is not available in Japan, Korea and mainland China (excluding Hong Kong and Taiwan). As a registered user of Nature Publishing Group's Web sites, our database indicates that you have opted-in to receive product information and special offers. If you no longer wish to receive these e-mails or to discontinue all e-mail services from Nature Publishing Group please update your online account. Modify My Account (Log in to be recognised as a Nature.com registrant). For further information on technical assistance | print subscriptions | other enquiries. Nature Publishing Group | Principal offices: London | New York and Tokyo, and offices in cities worldwide including Basingstoke | Barcelona | Boston | Buenos Aires | Cairo | Delhi | Heidelberg | Hong Kong | Madrid | Melbourne | Mexico City | Mumbai | Munich | Paris | San Francisco | Sao Paulo | Seoul and Washington DC. Macmillan Publishers Limited is a company incorporated in England & Wales under company number 785998 & whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. Nature Publishing Group | 75 Varick St Fl 9 | New York | NY 10013-1917 | USA © 2014 Nature Publishing Group, a division of Macmillan Publishers Limited. All rights reserved.