Translational Psychiatry Contents: 28 Dec 2021

The latest research from Translational Psychiatry: 28. December 2021

Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder Javier R. Caso , Karina S. MacDowell [...] Juan C. Leza Article | 21 December 2021 | Article number: 645 |  doi: 10.1038/s41398-021-01755-3

INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial Amy Goodwin , Emily J. H. Jones [...] Mark H. Johnson Article | 20 December 2021 | Article number: 644 |  doi: 10.1038/s41398-021-01698-9

Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment Iria Brocos-Mosquera , Patricia Miranda-Azpiazu [...] Guadalupe Rivero Article | 20 December 2021 | Article number: 643 |  doi: 10.1038/s41398-021-01762-4

Predictors of diagnostic transition from major depressive disorder to bipolar disorder: a retrospective observational network study Anastasiya Nestsiarovich , Jenna M. Reps [...] Christophe G. Lambert Article | 20 December 2021 | Article number: 642 |  doi: 10.1038/s41398-021-01760-6

Social buffering of human fear is shaped by gender, social concern, and the presence of real vs virtual agents Yanyan Qi , Dorothée Bruch [...] Grit Hein Article | 20 December 2021 | Article number: 641 |  doi: 10.1038/s41398-021-01761-5

Anxiety and depressive symptoms in college students during the late stage of the COVID-19 outbreak: a network approach Wei Bai , Hong Cai [...] Yu-Tao Xiang Article | 17 December 2021 | Article number: 638 |  doi: 10.1038/s41398-021-01738-4

Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses Abhishek Cukkemane , Nina Becker [...] Oliver H. Weiergräber Article | 17 December 2021 | Article number: 639 |  doi: 10.1038/s41398-021-01765-1

Effects of comorbid disorders on reward processing and connectivity in adults with ADHD Oliver Grimm , Daan van Rooij [...] Andreas Reif Article | 16 December 2021 | Article number: 636 |  doi: 10.1038/s41398-021-01758-0

Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume Yuanchao Zheng , Melanie E. Garrett [...] Rajendra A. Morey Article | 16 December 2021 | Article number: 637 |  doi: 10.1038/s41398-021-01707-x

A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone Hayley F. North , Christin Weissleder [...] Cynthia Shannon Weickert Article | 15 December 2021 | Article number: 635 |  doi: 10.1038/s41398-021-01742-8

Regional gray matter oligodendrocyte- and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans Kimberly L. P. Long , Linda L. Chao [...] Daniela Kaufer Article | 13 December 2021 | Article number: 631 |  doi: 10.1038/s41398-021-01745-5

Natural Language Processing markers in first episode psychosis and people at clinical high-risk Sarah E. Morgan , Kelly Diederen [...] Philip McGuire Article | 13 December 2021 | Article number: 630 |  doi: 10.1038/s41398-021-01722-y

Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation Sarah R. Moore , Thorhildur Halldorsdottir [...] Janine Arloth Article | 13 December 2021 | Article number: 632 |  doi: 10.1038/s41398-021-01756-2

Effects of escitalopram therapy on resting-state functional connectivity of subsystems of the default mode network in unmedicated patients with major depressive disorder Jian Cui , Yun Wang [...] Gang Wang Article | 13 December 2021 | Article number: 634 |  doi: 10.1038/s41398-021-01754-4

The association between depression and metabolic syndrome and its components: a bidirectional two-sample Mendelian randomization study Min Zhang , Jing Chen [...] Lihua Peng Article | 13 December 2021 | Article number: 633 |  doi: 10.1038/s41398-021-01759-z

Loneliness as an active ingredient in preventing or alleviating youth anxiety and depression: a critical interpretative synthesis incorporating principles from rapid realist reviews Eiluned Pearce , Pamela Myles-Hooton [...] Roz Shafran Review Article | 10 December 2021 | Article number: 628 |  doi: 10.1038/s41398-021-01740-w

Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder Rixing Lin , Juan Pablo Lopez [...] Gustavo Turecki Article | 10 December 2021 | Article number: 629 |  doi: 10.1038/s41398-021-01746-4

Anxiety and depression among Chinese adolescents during the COVID-19: an overestimation of the problem Lara Kojok , Katie Bodenstein [...] Alain Brunet Correspondence | 09 December 2021 | Article number: 624 |  doi: 10.1038/s41398-021-01748-2

Sex differences in neuronal systems function and behaviour: beyond a single diagnosis in autism spectrum disorders Olivia O. F. Williams, Madeleine Coppolino & Melissa L. Perreault Review Article | 09 December 2021 | Article number: 625 |  doi: 10.1038/s41398-021-01757-1

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium Takehiko Yamanashi , Takaaki Nagao [...] Gen Shinozaki Article | 09 December 2021 | Article number: 627 |  doi: 10.1038/s41398-021-01752-6

Systemic inflammation and emotional responses during the COVID-19 pandemic Odessa S. Hamilton, Dorina Cadar & Andrew Steptoe Article | 09 December 2021 | Article number: 626 |  doi: 10.1038/s41398-021-01753-5

Neurocognition and social cognition in patients with schizophrenia spectrum disorders with and without a history of violence: results of a multinational European study Laura Iozzino , Philip D. Harvey [...] Giovanni de Girolamo Article | 08 December 2021 | Article number: 620 |  doi: 10.1038/s41398-021-01749-1

Ibrutinib as a potential therapeutic for cocaine use disorder Spencer B. Huggett , Jeffrey S. Hatfield [...] Rohan H. C. Palmer Article | 08 December 2021 | Article number: 623 |  doi: 10.1038/s41398-021-01737-5

Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables Tatiana Oviedo-Salcedo , Elias Wagner [...] Alkomiet Hasan Article | 08 December 2021 | Article number: 621 |  doi: 10.1038/s41398-021-01751-7

Exercise rather than fluoxetine promotes oligodendrocyte differentiation and myelination in the hippocampus in a male mouse model of depression Jing Tang , Xin Liang [...] Yong Tang Article | 08 December 2021 | Article number: 622 |  doi: 10.1038/s41398-021-01747-3

Calcium imaging reveals depressive- and manic-phase-specific brain neural activity patterns in a murine model of bipolar disorder: a pilot study Min Chen , Hongjun Tian [...] Chuanjun Zhuo Article | 07 December 2021 | Article number: 619 |  doi: 10.1038/s41398-021-01750-8

Virtual reality: a powerful technology to provide novel insight into treatment mechanisms of addiction Massimiliano Mazza , Kornelius Kammler-Sücker [...] Bernd Lenz Systematic Review | 06 December 2021 | Article number: 617 |  doi: 10.1038/s41398-021-01739-3

Relationship between sensory characteristics and cortical thickness/volume in autism spectrum disorders Kaie Habata , Yongjeon Cheong [...] Hirotaka Kosaka Article | 06 December 2021 | Article number: 616 |  doi: 10.1038/s41398-021-01743-7

Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case–control study Emanuele F. Osimo , Mark Sweeney [...] Oliver D. Howes Article | 06 December 2021 | Article number: 614 |  doi: 10.1038/s41398-021-01741-9

Moderators of inflammation-related depression: a prospective study of breast cancer survivors Andrew W. Manigault , Patricia A. Ganz [...] Julienne E. Bower Article | 06 December 2021 | Article number: 615 |  doi: 10.1038/s41398-021-01744-6

Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci Hung-Hsin Chen , Lauren E. Petty [...] Jennifer E. Below Article | 06 December 2021 | Article number: 618 |  doi: 10.1038/s41398-021-01677-0

Association of low-frequency and rare coding variants with information processing speed Jan Bressler , Gail Davies [...] Ian J. Deary Article | 04 December 2021 | Article number: 613 |  doi: 10.1038/s41398-021-01736-6

Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach Louise Carton , Candice Niot [...] Julie Deguil Article | 03 December 2021 | Article number: 612 |  doi: 10.1038/s41398-021-01718-8

Can passive measurement of physiological distress help better predict suicidal thinking? Evan M. Kleiman , Kate H. Bentley [...] Matthew K. Nock Article | 02 December 2021 | Article number: 611 |  doi: 10.1038/s41398-021-01730-y

Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking Daria Piacentino , Silvia Grant-Beurmann [...] Lorenzo Leggio Article | 01 December 2021 | Article number: 609 |  doi: 10.1038/s41398-021-01728-6

Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients Kelly J. Heard , Maxim N. Shokhirev [...] Krishna C. Vadodaria Article | 30 November 2021 | Article number: 608 |  doi: 10.1038/s41398-021-01733-9

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients Klaus Oliver Schubert , Anbupalam Thalamuthu [...] Bernhard T. Baune Article | 29 November 2021 | Article number: 606 |  doi: 10.1038/s41398-021-01702-2

Insomnia with physiological hyperarousal is associated with lower weight: a novel finding and its clinical implications Rong Ren , Ye Zhang [...] Xiangdong Tang Article | 28 November 2021 | Article number: 604 |  doi: 10.1038/s41398-021-01672-5

Data-driven analysis of kappa opioid receptor binding in major depressive disorder measured by positron emission tomography Kelly Smart , Ashley Yttredahl [...] Jeffrey M. Miller Article | 27 November 2021 | Article number: 602 |  doi: 10.1038/s41398-021-01729-5

Psychological and biological resilience modulates the effects of stress on epigenetic aging Zachary M. Harvanek , Nia Fogelman [...] Rajita Sinha Article | 27 November 2021 | Article number: 601 |  doi: 10.1038/s41398-021-01735-7

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