Translational Psychiatry Contents: 31 Mar 2022

The latest content from Translational Psychiatry: 31 March 2022

Human forebrain organoids reveal connections between valproic acid exposure and autism risk Qingtuan Meng, Wendiao Zhang [...] Chao Chen Article | 29 March 2022 | Article number: 130 |  doi: 10.1038/s41398-022-01898-x

Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice André Miguel Miranda, Archana Ashok [...] Tal Nuriel Article | 29 March 2022 | Article number: 129 |  doi: 10.1038/s41398-022-01881-6

APOE-ε4 modulates the association among plasma Aβ42/Aβ40, vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adults Dai Shi, Siwei Xie [...] Tengfei Guo Article | 29 March 2022 | Article number: 128 |  doi: 10.1038/s41398-022-01899-w

In the era of whole-brain mapping for the exploration of mental disorders, we need to rethink our methods of rodent model establishment Chuanjun Zhuo, Hongjun Tian [...] Chunhua Zhou Correspondence | 28 March 2022 | Article number: 126 |  doi: 10.1038/s41398-022-01887-0

Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations Manish Kumar Tripathi, Maryam Kartawy [...] Haitham Amal Article | 28 March 2022 | Article number: 127 |  doi: 10.1038/s41398-022-01890-5

Apolipoprotein E Isoform-specific changes related to stress and trauma exposure Eileen Ruth S. Torres, Jenny Luo [...] Jacob Raber Article | 28 March 2022 | Article number: 125 |  doi: 10.1038/s41398-022-01848-7

Genetics of age-at-onset in major depression Arvid Harder, Thuy-Dung Nguyen [...] Yi Lu Article | 26 March 2022 | Article number: 124 |  doi: 10.1038/s41398-022-01888-z

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder Xiangning Xue, Wei Zong [...] Ryan W. Logan Article | 26 March 2022 | Article number: 123 |  doi: 10.1038/s41398-022-01894-1

Abnormal oligodendrocyte function in schizophrenia explains the long latent interval in some patients Jeffrey Fessel Review Article | 25 March 2022 | Article number: 120 |  doi: 10.1038/s41398-022-01879-0

Phosphodiesterase 2A inhibition corrects the aberrant behavioral traits observed in genetic and environmental preclinical models of Autism Spectrum Disorder Sara Schiavi, Emilia Carbone [...] Viviana Trezza Article | 25 March 2022 | Article number: 119 |  doi: 10.1038/s41398-022-01885-2

Disruption of 5-hydroxytryptamine 1A receptor and orexin receptor 1 heterodimer formation affects novel G protein-dependent signaling pathways and has antidepressant effects in vivo Rumin Zhang, Dandan Li [...] Jing Chen Article | 25 March 2022 | Article number: 122 |  doi: 10.1038/s41398-022-01886-1

Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US Maria Dalby, Morana Vitezic [...] Jordan W. Smoller Article | 25 March 2022 | Article number: 121 |  doi: 10.1038/s41398-022-01877-2

Sleep's role in updating aversive autobiographical memories Yasmine Azza, Frank H. Wilhelm [...] Ines Wilhelm Article | 24 March 2022 | Article number: 117 |  doi: 10.1038/s41398-022-01878-1

No increase in inflammation in late-life major depression screened to exclude physical illness Eline T. Luning Prak, Thomas Brooks [...] Yvette I. Sheline Article | 24 March 2022 | Article number: 118 |  doi: 10.1038/s41398-022-01883-4

Metabolite differences in the medial prefrontal cortex in schizophrenia patients with and without persistent auditory verbal hallucinations: a 1H MRS study Qianjin Wang, Honghong Ren [...] Jinsong Tang Article | 23 March 2022 | Article number: 116 |  doi: 10.1038/s41398-022-01866-5

Validation of a new instrument to guide and support insanity evaluations: the defendant's insanity assessment support scale (DIASS) Giovanna Parmigiani, Gabriele Mandarelli [...] Stefano Ferracuti Article | 22 March 2022 | Article number: 115 |  doi: 10.1038/s41398-022-01871-8

Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD Lili Wang, Jianhui Chen [...] Di Chen Article | 22 March 2022 | Article number: 114 |  doi: 10.1038/s41398-022-01875-4

Phenotypic and genetic analysis of a wellbeing factor score in the UK Biobank and the impact of childhood maltreatment and psychiatric illness Javad Jamshidi, Peter R. Schofield [...] Janice M. Fullerton Article | 19 March 2022 | Article number: 113 |  doi: 10.1038/s41398-022-01874-5

Parental autoimmune and autoinflammatory disorders as multiple risk factors for common neurodevelopmental disorders in offspring: a systematic review and meta-analysis Pierre Ellul, Eric Acquaviva [...] Richard Delorme Systematic Review | 18 March 2022 | Article number: 112 |  doi: 10.1038/s41398-022-01843-y

Memory-directed acupuncture as a neuromodulatory treatment for PTSD: Theory, clinical model and case studies Amir Assouline, Avi Mendelsohn & Alon Reshef Review Article | 17 March 2022 | Article number: 110 |  doi: 10.1038/s41398-022-01876-3

TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior Sudhirkumar Yanpallewar, Francesco Tomassoni-Ardori [...] Lino Tessarollo Article | 17 March 2022 | Article number: 111 |  doi: 10.1038/s41398-022-01869-2

Reduced cerebellar cortical thickness in World Trade Center responders with cognitive impairment Sean A. P. Clouston, Minos Kritikos [...] Benjamin J. Luft Article | 16 March 2022 | Article number: 107 |  doi: 10.1038/s41398-022-01873-6

Corticosterone induces discrete epigenetic signatures in the dorsal and ventral hippocampus that depend upon sex and genotype: focus on methylated Nr3c1 gene Salvatore G. Caradonna, Nathan R. Einhorn [...] Jordan Marrocco Article | 16 March 2022 | Article number: 109 |  doi: 10.1038/s41398-022-01864-7

Familial co-aggregation and shared heritability between depression, anxiety, obesity and substance use Rujia Wang, Harold Snieder & Catharina A. Hartman Article | 16 March 2022 | Article number: 108 |  doi: 10.1038/s41398-022-01868-3

Distinct neurocognitive bases for social trait judgments of faces in autism spectrum disorder Hongbo Yu, Runnan Cao [...] Shuo Wang Article | 15 March 2022 | Article number: 104 |  doi: 10.1038/s41398-022-01870-9

Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model Pamela M. Maras, Elaine K. Hebda-Bauer [...] Huda Akil Article | 15 March 2022 | Article number: 105 |  doi: 10.1038/s41398-022-01821-4

Targeted Tshz3 deletion in corticostriatal circuit components segregates core autistic behaviors Xavier Caubit, Paolo Gubellini [...] Laurent Fasano Article | 15 March 2022 | Article number: 106 |  doi: 10.1038/s41398-022-01865-6

Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior Margaret L. Westwater, Alexander G. Murley [...] Paul C. Fletcher Article | 15 March 2022 | Article number: 103 |  doi: 10.1038/s41398-022-01872-7

Clinical utility of combinatorial pharmacogenomic testing in depression: A Canadian patient- and rater-blinded, randomized, controlled trial Arun K. Tiwari, Clement C. Zai [...] James L. Kennedy Article | 14 March 2022 | Article number: 101 |  doi: 10.1038/s41398-022-01847-8

Distinct contributions of GluA1-containing AMPA receptors of different hippocampal subfields to salience processing, memory and impulse control Kasyoka Kilonzo, Daniel Strahnen [...] Dennis Kätzel Article | 14 March 2022 | Article number: 102 |  doi: 10.1038/s41398-022-01863-8

Neurophysiology in psychosis: The quest for disease biomarkers Baihan Wang, Eirini Zartaloudi [...] Elvira Bramon Review Article | 11 March 2022 | Article number: 100 |  doi: 10.1038/s41398-022-01860-x

Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic Hong Cai, Wei Bai [...] Yu-Tao Xiang Article | 10 March 2022 | Article number: 98 |  doi: 10.1038/s41398-022-01838-9

Sex-specific involvement of the Notch–JAG pathway in social recognition Hanna Jaaro-Peled, Melissa A. Landek-Salgado [...] Akira Sawa Article | 10 March 2022 | Article number: 99 |  doi: 10.1038/s41398-022-01867-4

Untargeted metabolic analysis in dried blood spots reveals metabolic signature in 22q11.2 deletion syndrome Dorinde Korteling, Marco P. Boks [...] Janneke R. Zinkstok Article | 09 March 2022 | Article number: 97 |  doi: 10.1038/s41398-022-01859-4

Genetic influences on central and peripheral nervous system activity during fear conditioning G. Kastrati, J. Rosén [...] F. Åhs Article | 08 March 2022 | Article number: 95 |  doi: 10.1038/s41398-022-01861-w

Inhibition of the ISR abrogates mGluR5-dependent long-term depression and spatial memory deficits in a rat model of Alzheimer's disease Zhengtao Hu, Pengpeng Yu [...] Neng-Wei Hu Article | 08 March 2022 | Article number: 96 |  doi: 10.1038/s41398-022-01862-9

Schizophrenia risk loci from xMHC region were associated with antipsychotic response in chronic schizophrenic patients with persistent positive symptom Jiang Li, Akane Yoshikawa [...] Herbert Y. Meltzer Article | 07 March 2022 | Article number: 92 |  doi: 10.1038/s41398-022-01854-9

Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory Emily J. Jaehne, Jessica N. Kent [...] Maarten van den Buuse Article | 07 March 2022 | Article number: 93 |  doi: 10.1038/s41398-022-01858-5

Stress vulnerability shapes disruption of motor cortical neuroplasticity Anne-Kathrin Gellner, Aileen Sitter [...] Valentin Stein Article | 04 March 2022 | Article number: 91 |  doi: 10.1038/s41398-022-01855-8

Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19: an observational multicenter study Nicolas Hoertel, Marina Sánchez-Rico [...] Frédéric Limosin Article | 03 March 2022 | Article number: 90 |  doi: 10.1038/s41398-022-01804-5

Insula network connectivity mediates the association between childhood maltreatment and depressive symptoms in major depressive disorder patients Cancan He, Dandan Fan [...] Chunming Xie Article | 02 March 2022 | Article number: 89 |  doi: 10.1038/s41398-022-01829-w

Metabolomic signature and mitochondrial dynamics outline the difference between vulnerability and resilience to chronic stress Paola Brivio, Matteo Audano [...] Francesca Calabrese Article | 28 February 2022 | Article number: 87 |  doi: 10.1038/s41398-022-01856-7

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