Cell Death and Disease - Table of Contents alert Volume 7, March 2016

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TABLE OF CONTENTS Volume 7, March 2016 In this issue News and Commentaries Review Original Articles Correspondence Meeting Report Sign up for e-alerts Web feed Advertisement Cell Death & Disease has now published over 2,000 open access articles. Spanning the breadth of translational implications of cell death, the journal seeks to promote diverse and integrated areas of experimental and internal medicine with its specialities, including cancer, cancer metabolism, immunity and neuroscience. Explore all content available. News and Commentaries Top αTAT1: a potential therapeutic target in cancer? J-Y Chien and C-H Lin Cell Death Dis 2016 7: e2172; 10.1038/cddis.2016.46 Full Text Preventing cell death with a ‘check valve’ in mitochondrial complex I? E Fontaine, D Detaille and G Vial Cell Death Dis 2016 7: e2165; 10.1038/cddis.2016.71 Full Text Mitochondrial DNA as an initiator of tumorigenesis W T Y Lee and J C St. John Cell Death Dis 2016 7: e2171; 10.1038/cddis.2016.77 Full Text NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells P Ruggeri, L Cappabianca, A R Farina, L Gneo and A R Mackay Cell Death Dis 2016 7: e2139; 10.1038/cddis.2016.49 Full Text Fat, sex and caspase-2 C H Wilson, L Dorstyn and S Kumar Cell Death Dis 2016 7: e2125; 10.1038/cddis.2016.40 Full Text Cathepsin B pulls the emergency brake on cellular necrosis F S Wouters and G Bunt Cell Death Dis 2016 7: e2170; 10.1038/cddis.2016.76 Full Text Diet-driven interferon-γ enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy X-j Xia, Y-y Che, J Zhang, Y-y Gao, C-j Ao, H-j Yang, J-x Liu, G-w Liu, W-y Han, Y-p Wang, J-q Wang and L-C Lei Cell Death Dis 2016 7: e2138; 10.1038/cddis.2016.48 Full Text Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors C K Yang and S D He Cell Death Dis 2016 7: e2126; 10.1038/cddis.2016.25 Full Text Review Top Necroptosis in acute kidney injury: a shedding light S Wang, C Zhang, L Hu and C Yang Cell Death Dis 2016 7: e2125; 10.1038/cddis.2016.37 Abstract | Full Text Original Articles Top Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection C Agrati, C Castilletti, R Casetti, A Sacchi, L Falasca, F Turchi, N Tumino, V Bordoni, E Cimini, D Viola, E Lalle, L Bordi, S Lanini, F Martini, E Nicastri, N Petrosillo, V Puro, M Piacentini, A Di Caro, G P Kobinger, A Zumla, G Ippolito and M R Capobianchi Cell Death Dis 2016 7: e2164; 10.1038/cddis.2016.55 Abstract | Full Text p53MutaGene: an online tool to estimate the effect of p53 mutational status on gene regulation in cancer I Amelio, R A Knight, A Lisitsa, G Melino and A V Antonov Cell Death Dis 2016 7: e2148; 10.1038/cddis.2016.42 Abstract | Full Text Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells Y Bai, Q Shang, H Zhao, Z Pan, C Guo, L Zhang and Q Wang Cell Death Dis 2016 7: e2169; 10.1038/cddis.2016.75 Abstract | Full Text Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine D Cai, E Huang, B Luo, Y Yang, F Zhang, C Liu, Z Lin, W-B Xie and H Wang Cell Death Dis 2016 7: e2161; 10.1038/cddis.2016.67 Abstract | Full Text Sodium–hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertility Su-Ren Chen, M Chen, S-L Deng, X-X Hao, X-X Wang and Y-X Liu Cell Death Dis 2016 7: e2152; 10.1038/cddis.2016.65 Abstract | Full Text Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic target A Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, C A Wassif, W Zheng and F D Porter Cell Death Dis 2016 7: e2147; 10.1038/cddis.2016.16 Abstract | Full Text Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation E Datan, S G Roy, G Germain, N Zali, J E McLean, G Golshan, S Harbajan, R A Lockshin and Z Zakeri Cell Death Dis 2016 7: e2127; 10.1038/cddis.2015.409 Abstract | Full Text Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway C Dou, N Ding, J Xing, C Zhao, F Kang, T Hou, H Quan, Y Chen, Q Dai, F Luo, J Xu and S Dong Cell Death Dis 2016 7: e2162; 10.1038/cddis.2016.69 Abstract | Full Text NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism T Elmetwali, A Salman and D H Palmer Cell Death Dis 2016 7: e2146; 10.1038/cddis.2016.52 Abstract | Full Text The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis P Fortini, C Ferretti, E Iorio, M Cagnin, L Garribba, D Pietraforte, M Falchi, B Pascucci, S Baccarini, F Morani, S Phadngam, G De Luca, C Isidoro and E Dogliotti Cell Death Dis 2016 7: e2168; 10.1038/cddis.2016.50 Abstract | Full Text Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis S Grabow, G L Kelly, A R D Delbridge, P N Kelly, P Bouillet, J M Adams and A Strasser Cell Death Dis 2016 7: e2132; 10.1038/cddis.2016.43 Abstract | Full Text Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling Y Han, Z Wu, T Wu, Y Huang, Z Cheng, X Li, T Sun, X Xie, Y Zhou and Z Du Cell Death Dis 2016 7: e2123; 10.1038/cddis.2015.407 Abstract | Full Text Adipogenic placenta-derived mesenchymal stem cells are not lineage restricted by withdrawing extrinsic factors: developing a novel visual angle in stem cell biology C Hu, H Cao, X Pan, J Li, J He, Q Pan, J Xin, X Yu, J Li, Y Wang, D Zhu and L Li Cell Death Dis 2016 7: e2141; 10.1038/cddis.2016.1 Abstract | Full Text Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway Z Huang, L Zhang, Y Chen, H Zhang, Q Zhang, R Li, J Ma, Z Li, C Yu, Y Lai, T Lin, X Zhao, B Zhang, Z Ye, S Liu, W Wang, X Liang, R Liao and W Shi Cell Death Dis 2016 7: e2142; 10.1038/cddis.2016.51 Abstract | Full Text Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy J H Kang, J-S Lee, D Hong, S-H Lee, N Kim, W-K Lee, T-W Sung, Y-D Gong and S-Y Kim Cell Death Dis 2016 7: e2163; 10.1038/cddis.2016.14 Abstract | Full Text Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure A P Komarov, E A Komarova, K Green, L R Novototskaya, P S Baker, A Eroshkin, A L Osterman, A A Chenchick, C Frangou and A V Gudkov Cell Death Dis 2016 7: e2145; 10.1038/cddis.2016.45 Abstract | Full Text Glycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activation H J Lee, J M Ryu, Y H Jung, K H Lee, D I Kim and H J Han Cell Death Dis 2016 7: e2158; 10.1038/cddis.2015.410 Abstract | Full Text Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson’s disease S Lehmann, A C Costa, I Celardo, S H Y Loh and L M Martins Cell Death Dis 2016 7: e2166; 10.1038/cddis.2016.72 Abstract | Full Text A long non-coding RNA interacts with Gfra1 and maintains survival of mouse spermatogonial stem cells L Li, M Wang, M Wang, X Wu, L Geng, Y Xue, X Wei, Y Jia and X Wu Cell Death Dis 2016 7: e2140; 10.1038/cddis.2016.24 Abstract | Full Text Wnt activation protects against neomycin-induced hair cell damage in the mouse cochlea L Liu, Y Chen, J Qi, Y Zhang, Y He, W Ni, W Li, S Zhang, S Sun, M M Taketo, L Wang, R Chai and H Li Cell Death Dis 2016 7: e2136; 10.1038/cddis.2016.35 Abstract | Full Text miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma Y Liu, R Zhao, H Wang, Y Luo, X Wang, W Niu, Y Zhou, Q Wen, S Fan, X Li, W Xiong, J Ma, X Li, M Tan, G Li and M Zhou Cell Death Dis 2016 7: e2156; 10.1038/cddis.2016.64 Abstract | Full Text MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expression C Lou, M Xiao, S Cheng, X Lu, S Jia, Y Ren and Z Li Cell Death Dis 2016 7: e2159; 10.1038/cddis.2016.27 Abstract | Full Text ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells N Luo, J Guo, L Chen, W Yang, X Qu and Z Cheng Cell Death Dis 2016 7: e2157; 10.1038/cddis.2015.401 Abstract | Full Text Paravascular pathways contribute to vasculitis and neuroinflammation after subarachnoid hemorrhage independently of glymphatic control C Luo, X Yao, J Li, B He, Q Liu, H Ren, F Liang, M Li, H Lin, J Peng, T F Yuan, Z Pei and H Su Cell Death Dis 2016 7: e2160; 10.1038/cddis.2016.63 Abstract | Full Text From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitor Y Mu, Y Liu, J Xiang, Q Zhang, S Zhai, D P Russo, H Zhu, X Bai and B Yan Cell Death Dis 2016 7: e2143; 10.1038/cddis.2016.53 Abstract | Full Text GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling S Parida, I Pal, A Parekh, B Thakur, R Bharti, S Das and M Mandal Cell Death Dis 2016 7: e2154; 10.1038/cddis.2016.61 Abstract | Full Text Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells G Pathria, B Garg, V Borgdorff, K Garg, C Wagner, G Superti-Furga and S N Wagner Cell Death Dis 2016 7: e2135; 10.1038/cddis.2015.369 Abstract | Full Text Autophagy regulates odontoblast differentiation by suppressing NF-κB activation in an inflammatory environment F Pei, H S Wang, Z Chen and L Zhang Cell Death Dis 2016 7: e2122; 10.1038/cddis.2015.397 Abstract | Full Text Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α F Ren, L Zhang, X Zhang, H Shi, T Wen, L Bai, S Zheng, Y Chen, D Chen, L Li and Z Duan Cell Death Dis 2016 7: e2151; 10.1038/cddis.2016.56 Abstract | Full Text IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways J Shi, H Wang, H Guan, S Shi, Y Li, X Wu, N Li, C Yang, X Bai, W Cai, F Yang, X Wang, L Su, Z Zheng and D Hu Cell Death Dis 2016 7: e2133; 10.1038/cddis.2016.44 Abstract | Full Text MiR-125a-5p decreases after long non-coding RNA HOTAIR knockdown to promote cancer cell apoptosis by releasing caspase 2 L Tang, H Shen, X Li, Z Li, Z Liu, J Xu, S Ma, X Zhao, X Bai, M Li, Q Wang and J Ji Cell Death Dis 2016 7: e2137; 10.1038/cddis.2016.41 Abstract | Full Text LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway X Wang, W Zhang, J Tang, R Huang, J Li, D Xu, Y Xie, R Jiang, L Deng, X Zhang, Y Chai, X Qin and B Sun Cell Death Dis 2016 7: e2130; 10.1038/cddis.2016.26 Abstract | Full Text Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system K Wang, R Xu, A J Snider, J Schrandt, Y Li, A B Bialkowska, M Li, J Zhou, Y A Hannun, L M Obeid, V W Yang and C Mao Cell Death Dis 2016 7: e2124; 10.1038/cddis.2016.36 Abstract | Full Text Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation C Wang, C Qu, Y Alippe, S L Bonar, R Civitelli, Y Abu-Amer, M O Hottiger and G Mbalaviele Cell Death Dis 2016 7: e2153; 10.1038/cddis.2016.58 Abstract | Full Text Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy D W L Wong, W H Yiu, H J Wu, R X Li, Y Liu, K W Chan, J C K Leung, L Y Y Chan, K N Lai and S C W Tang Cell Death Dis 2016 7: e2155; 10.1038/cddis.2016.62 Abstract | Full Text Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus Y Xi, J S Dhaliwal, M Ceizar, M Vaculik, K L Kumar and D C Lagace Cell Death Dis 2016 7: e2127; 10.1038/cddis.2015.406 Abstract | Full Text Long non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemia Q Xu, F Deng, Z Xing, Z Wu, B Cen, S Xu, Z Zhao, R Nepomuceno, M I H Bhuiyan, D Sun, Q J Wang and A Ji Cell Death Dis 2016 7: e2173; 10.1038/cddis.2016.57 Abstract | Full Text Local proliferation initiates macrophage accumulation in adipose tissue during obesity C Zheng, Q Yang, J Cao, N Xie, K Liu, P Shou, F Qian, Y Wang and Y Shi Cell Death Dis 2016 7: e2167; 10.1038/cddis.2016.54 Abstract | Full Text The oncolytic peptide LTX-315 triggers immunogenic cell death H Zhou, S Forveille, A Sauvat, T Yamazaki, L Senovilla, Y Ma, P Liu, H Yang, L Bezu, K Müller, L Zitvogel, Ø Rekdal, O Kepp and G Kroemer Cell Death Dis 2016 7: e2134; 10.1038/cddis.2016.47 Abstract | Full Text Correspondence Top Rescue from early-onset hearing loss in a mouse model lacking the cyclin-dependent kinase inhibitor p19Ink4d Q Ma, M Grati, F Bai, J Pei, X-H Pei and X Liu Cell Death Dis 2016 7: e2131; 10.1038/cddis.2016.38 Full Text Meeting Report Top The 7th Barossa Meeting—Cell Signalling in Cancer Biology and Therapy in Barossa Valley, Australia M A Grimbaldeston, V M Dixit and M S Samuel Cell Death Dis 2016 7: e2129; 10.1038/cddis.2016.39 Full Text Advertisement Online-only and open access, Cell Death Discovery will publish scientifically sound research at the intersection of cell death and medicine. 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