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TABLE OF CONTENTS
| | | | Volume 7, March 2016 | | In this issue News and Commentaries Review Original Articles Correspondence Meeting Report | | | | | Advertisement | | Cell Death & Disease has now published over 2,000 open access articles.
Spanning the breadth of translational implications of cell death, the journal seeks to promote diverse and integrated areas of experimental and internal medicine with its specialities, including cancer, cancer metabolism, immunity and neuroscience.
Explore all content available. | | | | | | News and Commentaries | Top | | αTAT1: a potential therapeutic target in cancer?J-Y Chien and C-H Lin Cell Death Dis 2016 7: e2172; 10.1038/cddis.2016.46 Full Text | | | | Preventing cell death with a ‘check valve’ in mitochondrial complex I?E Fontaine, D Detaille and G Vial Cell Death Dis 2016 7: e2165; 10.1038/cddis.2016.71 Full Text | | | | Mitochondrial DNA as an initiator of tumorigenesisW T Y Lee and J C St. John Cell Death Dis 2016 7: e2171; 10.1038/cddis.2016.77 Full Text | | | | NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cellsP Ruggeri, L Cappabianca, A R Farina, L Gneo and A R Mackay Cell Death Dis 2016 7: e2139; 10.1038/cddis.2016.49 Full Text | | | | Fat, sex and caspase-2C H Wilson, L Dorstyn and S Kumar Cell Death Dis 2016 7: e2125; 10.1038/cddis.2016.40 Full Text | | | | Cathepsin B pulls the emergency brake on cellular necrosisF S Wouters and G Bunt Cell Death Dis 2016 7: e2170; 10.1038/cddis.2016.76 Full Text | | | | Diet-driven interferon-γ enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagyX-j Xia, Y-y Che, J Zhang, Y-y Gao, C-j Ao, H-j Yang, J-x Liu, G-w Liu, W-y Han, Y-p Wang, J-q Wang and L-C Lei Cell Death Dis 2016 7: e2138; 10.1038/cddis.2016.48 Full Text | | | | Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectorsC K Yang and S D He Cell Death Dis 2016 7: e2126; 10.1038/cddis.2016.25 Full Text | | Review | Top | | Necroptosis in acute kidney injury: a shedding lightS Wang, C Zhang, L Hu and C Yang Cell Death Dis 2016 7: e2125; 10.1038/cddis.2016.37 Abstract | Full Text | | Original Articles | Top | | Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infectionC Agrati, C Castilletti, R Casetti, A Sacchi, L Falasca, F Turchi, N Tumino, V Bordoni, E Cimini, D Viola, E Lalle, L Bordi, S Lanini, F Martini, E Nicastri, N Petrosillo, V Puro, M Piacentini, A Di Caro, G P Kobinger, A Zumla, G Ippolito and M R Capobianchi Cell Death Dis 2016 7: e2164; 10.1038/cddis.2016.55 Abstract | Full Text | | | | p53MutaGene: an online tool to estimate the effect of p53 mutational status on gene regulation in cancerI Amelio, R A Knight, A Lisitsa, G Melino and A V Antonov Cell Death Dis 2016 7: e2148; 10.1038/cddis.2016.42 Abstract | Full Text | | | | Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cellsY Bai, Q Shang, H Zhao, Z Pan, C Guo, L Zhang and Q Wang Cell Death Dis 2016 7: e2169; 10.1038/cddis.2016.75 Abstract | Full Text | | | | Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamineD Cai, E Huang, B Luo, Y Yang, F Zhang, C Liu, Z Lin, W-B Xie and H Wang Cell Death Dis 2016 7: e2161; 10.1038/cddis.2016.67 Abstract | Full Text | | | | Sodium–hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertilitySu-Ren Chen, M Chen, S-L Deng, X-X Hao, X-X Wang and Y-X Liu Cell Death Dis 2016 7: e2152; 10.1038/cddis.2016.65 Abstract | Full Text | | | | Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic targetA Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, C A Wassif, W Zheng and F D Porter Cell Death Dis 2016 7: e2147; 10.1038/cddis.2016.16 Abstract | Full Text | | | | Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activationE Datan, S G Roy, G Germain, N Zali, J E McLean, G Golshan, S Harbajan, R A Lockshin and Z Zakeri Cell Death Dis 2016 7: e2127; 10.1038/cddis.2015.409 Abstract | Full Text | | | | Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathwayC Dou, N Ding, J Xing, C Zhao, F Kang, T Hou, H Quan, Y Chen, Q Dai, F Luo, J Xu and S Dong Cell Death Dis 2016 7: e2162; 10.1038/cddis.2016.69 Abstract | Full Text | | | | NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanismT Elmetwali, A Salman and D H Palmer Cell Death Dis 2016 7: e2146; 10.1038/cddis.2016.52 Abstract | Full Text | | | | The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesisP Fortini, C Ferretti, E Iorio, M Cagnin, L Garribba, D Pietraforte, M Falchi, B Pascucci, S Baccarini, F Morani, S Phadngam, G De Luca, C Isidoro and E Dogliotti Cell Death Dis 2016 7: e2168; 10.1038/cddis.2016.50 Abstract | Full Text | | | | Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesisS Grabow, G L Kelly, A R D Delbridge, P N Kelly, P Bouillet, J M Adams and A Strasser Cell Death Dis 2016 7: e2132; 10.1038/cddis.2016.43 Abstract | Full Text | | | | Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signalingY Han, Z Wu, T Wu, Y Huang, Z Cheng, X Li, T Sun, X Xie, Y Zhou and Z Du Cell Death Dis 2016 7: e2123; 10.1038/cddis.2015.407 Abstract | Full Text | | | | Adipogenic placenta-derived mesenchymal stem cells are not lineage restricted by withdrawing extrinsic factors: developing a novel visual angle in stem cell biologyC Hu, H Cao, X Pan, J Li, J He, Q Pan, J Xin, X Yu, J Li, Y Wang, D Zhu and L Li Cell Death Dis 2016 7: e2141; 10.1038/cddis.2016.1 Abstract | Full Text | | | | Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathwayZ Huang, L Zhang, Y Chen, H Zhang, Q Zhang, R Li, J Ma, Z Li, C Yu, Y Lai, T Lin, X Zhao, B Zhang, Z Ye, S Liu, W Wang, X Liang, R Liao and W Shi Cell Death Dis 2016 7: e2142; 10.1038/cddis.2016.51 Abstract | Full Text | | | | Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagyJ H Kang, J-S Lee, D Hong, S-H Lee, N Kim, W-K Lee, T-W Sung, Y-D Gong and S-Y Kim Cell Death Dis 2016 7: e2163; 10.1038/cddis.2016.14 Abstract | Full Text | | | | Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failureA P Komarov, E A Komarova, K Green, L R Novototskaya, P S Baker, A Eroshkin, A L Osterman, A A Chenchick, C Frangou and A V Gudkov Cell Death Dis 2016 7: e2145; 10.1038/cddis.2016.45 Abstract | Full Text | | | | Glycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activationH J Lee, J M Ryu, Y H Jung, K H Lee, D I Kim and H J Han Cell Death Dis 2016 7: e2158; 10.1038/cddis.2015.410 Abstract | Full Text | | | | Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson’s diseaseS Lehmann, A C Costa, I Celardo, S H Y Loh and L M Martins Cell Death Dis 2016 7: e2166; 10.1038/cddis.2016.72 Abstract | Full Text | | | | A long non-coding RNA interacts with Gfra1 and maintains survival of mouse spermatogonial stem cellsL Li, M Wang, M Wang, X Wu, L Geng, Y Xue, X Wei, Y Jia and X Wu Cell Death Dis 2016 7: e2140; 10.1038/cddis.2016.24 Abstract | Full Text | | | | Wnt activation protects against neomycin-induced hair cell damage in the mouse cochleaL Liu, Y Chen, J Qi, Y Zhang, Y He, W Ni, W Li, S Zhang, S Sun, M M Taketo, L Wang, R Chai and H Li Cell Death Dis 2016 7: e2136; 10.1038/cddis.2016.35 Abstract | Full Text | | | | miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinomaY Liu, R Zhao, H Wang, Y Luo, X Wang, W Niu, Y Zhou, Q Wen, S Fan, X Li, W Xiong, J Ma, X Li, M Tan, G Li and M Zhou Cell Death Dis 2016 7: e2156; 10.1038/cddis.2016.64 Abstract | Full Text | | | | MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expressionC Lou, M Xiao, S Cheng, X Lu, S Jia, Y Ren and Z Li Cell Death Dis 2016 7: e2159; 10.1038/cddis.2016.27 Abstract | Full Text | | | | ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cellsN Luo, J Guo, L Chen, W Yang, X Qu and Z Cheng Cell Death Dis 2016 7: e2157; 10.1038/cddis.2015.401 Abstract | Full Text | | | | Paravascular pathways contribute to vasculitis and neuroinflammation after subarachnoid hemorrhage independently of glymphatic controlC Luo, X Yao, J Li, B He, Q Liu, H Ren, F Liang, M Li, H Lin, J Peng, T F Yuan, Z Pei and H Su Cell Death Dis 2016 7: e2160; 10.1038/cddis.2016.63 Abstract | Full Text | | | | From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitorY Mu, Y Liu, J Xiang, Q Zhang, S Zhai, D P Russo, H Zhu, X Bai and B Yan Cell Death Dis 2016 7: e2143; 10.1038/cddis.2016.53 Abstract | Full Text | | | | GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signalingS Parida, I Pal, A Parekh, B Thakur, R Bharti, S Das and M Mandal Cell Death Dis 2016 7: e2154; 10.1038/cddis.2016.61 Abstract | Full Text | | | | Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cellsG Pathria, B Garg, V Borgdorff, K Garg, C Wagner, G Superti-Furga and S N Wagner Cell Death Dis 2016 7: e2135; 10.1038/cddis.2015.369 Abstract | Full Text | | | | Autophagy regulates odontoblast differentiation by suppressing NF-κB activation in an inflammatory environmentF Pei, H S Wang, Z Chen and L Zhang Cell Death Dis 2016 7: e2122; 10.1038/cddis.2015.397 Abstract | Full Text | | | | Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor αF Ren, L Zhang, X Zhang, H Shi, T Wen, L Bai, S Zheng, Y Chen, D Chen, L Li and Z Duan Cell Death Dis 2016 7: e2151; 10.1038/cddis.2016.56 Abstract | Full Text | | | | IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathwaysJ Shi, H Wang, H Guan, S Shi, Y Li, X Wu, N Li, C Yang, X Bai, W Cai, F Yang, X Wang, L Su, Z Zheng and D Hu Cell Death Dis 2016 7: e2133; 10.1038/cddis.2016.44 Abstract | Full Text | | | | MiR-125a-5p decreases after long non-coding RNA HOTAIR knockdown to promote cancer cell apoptosis by releasing caspase 2L Tang, H Shen, X Li, Z Li, Z Liu, J Xu, S Ma, X Zhao, X Bai, M Li, Q Wang and J Ji Cell Death Dis 2016 7: e2137; 10.1038/cddis.2016.41 Abstract | Full Text | | | | LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathwayX Wang, W Zhang, J Tang, R Huang, J Li, D Xu, Y Xie, R Jiang, L Deng, X Zhang, Y Chai, X Qin and B Sun Cell Death Dis 2016 7: e2130; 10.1038/cddis.2016.26 Abstract | Full Text | | | | Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune systemK Wang, R Xu, A J Snider, J Schrandt, Y Li, A B Bialkowska, M Li, J Zhou, Y A Hannun, L M Obeid, V W Yang and C Mao Cell Death Dis 2016 7: e2124; 10.1038/cddis.2016.36 Abstract | Full Text | | | | Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturationC Wang, C Qu, Y Alippe, S L Bonar, R Civitelli, Y Abu-Amer, M O Hottiger and G Mbalaviele Cell Death Dis 2016 7: e2153; 10.1038/cddis.2016.58 Abstract | Full Text | | | | Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathyD W L Wong, W H Yiu, H J Wu, R X Li, Y Liu, K W Chan, J C K Leung, L Y Y Chan, K N Lai and S C W Tang Cell Death Dis 2016 7: e2155; 10.1038/cddis.2016.62 Abstract | Full Text | | | | Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampusY Xi, J S Dhaliwal, M Ceizar, M Vaculik, K L Kumar and D C Lagace Cell Death Dis 2016 7: e2127; 10.1038/cddis.2015.406 Abstract | Full Text | | | | Long non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemiaQ Xu, F Deng, Z Xing, Z Wu, B Cen, S Xu, Z Zhao, R Nepomuceno, M I H Bhuiyan, D Sun, Q J Wang and A Ji Cell Death Dis 2016 7: e2173; 10.1038/cddis.2016.57 Abstract | Full Text | | | | Local proliferation initiates macrophage accumulation in adipose tissue during obesityC Zheng, Q Yang, J Cao, N Xie, K Liu, P Shou, F Qian, Y Wang and Y Shi Cell Death Dis 2016 7: e2167; 10.1038/cddis.2016.54 Abstract | Full Text | | | | The oncolytic peptide LTX-315 triggers immunogenic cell deathH Zhou, S Forveille, A Sauvat, T Yamazaki, L Senovilla, Y Ma, P Liu, H Yang, L Bezu, K Müller, L Zitvogel, Ø Rekdal, O Kepp and G Kroemer Cell Death Dis 2016 7: e2134; 10.1038/cddis.2016.47 Abstract | Full Text | | Correspondence | Top | | Rescue from early-onset hearing loss in a mouse model lacking the cyclin-dependent kinase inhibitor p19Ink4dQ Ma, M Grati, F Bai, J Pei, X-H Pei and X Liu Cell Death Dis 2016 7: e2131; 10.1038/cddis.2016.38 Full Text | | Meeting Report | Top | | The 7th Barossa Meeting—Cell Signalling in Cancer Biology and Therapy in Barossa Valley, AustraliaM A Grimbaldeston, V M Dixit and M S Samuel Cell Death Dis 2016 7: e2129; 10.1038/cddis.2016.39 Full Text | | | | | Advertisement | | Online-only and open access, Cell Death Discovery will publish scientifically sound research at the intersection of cell death and medicine. Increasing the reproducibility of research, the journal will foster a dynamic dialogue with a focus on cancer, neurobiology and inflammation research.
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