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2015/07/03

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One of the questions that has been particularly vexing is why the 1918 pandemic human influenza A virus killed so many young

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Exposure to previous strains of flu virus does offer some protection to new strains. This is because the immune system reacts to

 

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But why was that particular pandemic so deadly? Where did the virus come from and why was it so severe? These questions have dogged scientists ever since. Now, a new study led by the University of Arizona (UA) may have solved the mystery. Michael Worobey, a professor in UA College of Science's Department of Ecology and Evolutionary Biology, and colleagues describe their findings in the Proceedings of the National Academy of Sciences. They hope the study not only offers some new clues about the deadliness of the 1918 pandemic, but will also help improve strategies for vaccination and pandemic prevention, as Prof. Worobey explains: "If our model is correct, then current medical interventions, especially antibiotics and vaccines, against several pneumonia-causing bacteria, could be expected to dramatically reduce mortality, if we were faced today with a similar set of pandemic ingredients."

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