TABLE OF CONTENTS
| | | | Volume 37, Issue 3 (March 2016) | | In this issue Reviews Original Articles
Also new AOP | | | | Reviews | Top | | Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseasesRui Liu and Christopher G Proud Acta Pharmacol Sin 2016 37: 285-294; advance online publication, January 25, 2016; 10.1038/aps.2015.123 Abstract | Full Text | | | | Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapyYu-shuang Zhang, Qiang Shen and Jing Li Acta Pharmacol Sin 2015 37: 295-302; advance online publication, December 28, 2015; 10.1038/aps.2015.116 Abstract | Full Text | | Original Articles | Top | | Activity- and development-dependent down-regulation of TARPγ8 and GluA1 in cultured rat hippocampal neuronsJian-gang Wang, Ya-li Wang, Fang Xu, Jing-xi Zhao, Si-yuan Zhou, Yi Yu, Paul L Chazot, Xiao-fang Wang and Cheng-biao Lu Acta Pharmacol Sin 2016 37: 303-311; advance online publication, January 4, 2016; 10.1038/aps.2015.112 Abstract | Full Text | | | | Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neuronsLei Shen, Wen-yu Cui, Ru-zhu Chen and Hai Wang Acta Pharmacol Sin 2016 37: 312-321; advance online publication, January 25, 2016; 10.1038/aps.2015.106 Abstract | Full Text | | | | Y-QA31, a novel dopamine D3 receptor antagonist, exhibits antipsychotic-like properties in preclinical animal models of schizophreniaXue Sun, Hong-yan Gou, Fei Li, Guan-yi Lu, Rui Song, Ri-fang Yang, Ning Wu, Rui-bin Su, Bin Cong and Jin Li Acta Pharmacol Sin 2016 37: 322-333; advance online publication, January 18, 2016; 10.1038/aps.2015.105 Abstract | Full Text | | | | A novel synthetic compound MCAP suppresses LPS-induced murine microglial activation in vitro via inhibiting NF-kB and p38 MAPK pathwaysByung-Wook Kim, Sandeep Vasant More, Yo-Sep Yun, Hyun-Myung Ko, Jae-Hwan Kwak, Heesoon Lee, Kyoungho Suk, In-Su Kim and Dong-Kug Choi Acta Pharmacol Sin 2016 37: 334-343; advance online publication, February 1, 2016; 10.1038/aps.2015.138 Abstract | Full Text | | | | Sulforaphane prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating SIRT1 and subsequently inhibiting ER stressYun-peng Li, Shu-lin Wang, Bei Liu, Lu Tang, Rong-ren Kuang, Xian-bao Wang, Cong Zhao, Xu-dong Song, Xue-ming Cao, Xiang Wu, Ping-zhen Yang, Li-zi Wang and Ai-hua Chen Acta Pharmacol Sin 2016 37: 344-353; advance online publication, January 18, 2016; 10.1038/aps.2015.130 Abstract | Full Text | | | | Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stressGuo-long Zhao, Li-ming Yu, Wen-li Gao, Wei-xun Duan, Bo Jiang, Xu-dong Liu, Bin Zhang, Zhen-hua Liu, Meng-en Zhai, Zhen-xiao Jin, Shi-qiang Yu and Yun Wang Acta Pharmacol Sin 2016 37: 354-367; advance online publication, January 25, 2016; 10.1038/aps.2015.136 Abstract | Full Text | | | | Ophiopogonin D maintains Ca2+ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stressWen-ting You, Tao Zhou, Zeng-chun Ma, Qian-de Liang, Cheng-rong Xiao, Xiang-lin Tang, Hong-ling Tan, Bo-li Zhang, Yu-guang Wang and Yue Gao Acta Pharmacol Sin 2016 37: 368-381; advance online publication, February 1, 2016; 10.1038/aps.2015.146 Abstract | Full Text | | | | Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathwayYi-ming Jiang, Ying Wang, Hua-sen Tan, Tao Yu, Xiao-mei Fan, Pan Chen, Hang Zeng, Min Huang and Hui-chang Bi Acta Pharmacol Sin 2016 37: 382-389; advance online publication, January 25, 2016; 10.1038/aps.2015.120 Abstract | Full Text | | | | Genetic variants of CDH13 determine the susceptibility to chronic obstructive pulmonary disease in a Chinese populationYi-ming Yuan, Jin-long Zhang, Si-cheng Xu, Ren-song Ye, Dan Xu, You Zhang, Yan-Jie Zhang, Yu-long Chen, Yu-lan Liu and Zhi-guang Su Acta Pharmacol Sin 2016 37: 390-397; advance online publication, January 25, 2016; 10.1038/aps.2015.158 Abstract | Full Text | | | | DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivoMeng-yuan Li, Yong-cong Lv, Lin-jiang Tong, Ting Peng, Rong Qu, Tao Zhang, Yi-ming Sun, Yi Chen, Li-xin Wei, Mei-yu Geng, Wen-hu Duan, Hua Xie and Jian Ding Acta Pharmacol Sin 2016 37: 398-407; advance online publication, January 25, 2016; 10.1038/aps.2015.117 Abstract | Full Text | | | | Pharmacokinetics and pharmacodynamics of SCT800, a new recombinant FVIII, in hemophilia A miceRuo-lan Gu, Liang Liu, Liang-zhi Xie, Wen-lin Gai, Si-shuo Cao, Zhi-yun Meng, Hui Gan, Zhuo-na Wu, Jian Li, Ying Zheng, Xiao-xia Zhu and Gui-fang Dou Acta Pharmacol Sin 2016 37: 408-414; advance online publication, January 25, 2016; 10.1038/aps.2015.121 Abstract | Full Text | | | | Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicityLei-lei Ma, Zhi-tao Wu, Le Wang, Xue-feng Zhang, Jing Wang, Chen Chen, Xuan Ni, Yun-fei Lin, Yi-yi Cao, Yang Luan and Guo-yu Pan Acta Pharmacol Sin 2016 37: 415-424; advance online publication, January 25, 2016; 10.1038/aps.2015.157 Abstract | Full Text | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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