Cell Death and Disease - Table of Contents alert Volume 5, February 2014

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TABLE OF CONTENTS Volume 5, February 2014 In this issue Editorial Reviews Original Articles Sign up for e-alerts Web feed Editorial Top The 1000th publication features protection of normal cells during chemotherapy: a land mark for Cell Death & Disease Y Shi Cell Death Dis 2014 5: e1062; 10.1038/cddis.2014.50 Full Text Reviews Top Metabolism addiction in pancreatic cancer R Blum and Y Kloog Cell Death Dis 2014 5: e1065; 10.1038/cddis.2014.38 Abstract | Full Text Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer Y Chen, L L Fu, X Wen, X Y Wang, J Liu, Y Cheng and J Huang Cell Death Dis 2014 5: e1047; 10.1038/cddis.2014.14 Abstract | Full Text Original Articles Top Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein W Abbas, K A Khan, A Kumar, M K Tripathy, I Dichamp, M Keita, U Mahlknecht, O Rohr and G Herbein Cell Death Dis 2014 5: e1080; 10.1038/cddis.2014.16 Abstract | Full Text DRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information I Amelio, M Gostev, R A Knight, A E Willis, G Melino and A V Antonov Cell Death Dis 2014 5: e1051; 10.1038/cddis.2014.9 Abstract | Full Text PlGF–MMP9-engineered iPS cells supported on a PEG–fibrinogen hydrogel scaffold possess an enhanced capacity to repair damaged myocardium C Bearzi, C Gargioli, D Baci, O Fortunato, K Shapira-Schweitzer, O Kossover, M V G Latronico, D Seliktar, G Condorelli and R Rizzi Cell Death Dis 2014 5: e1053; 10.1038/cddis.2014.12 Abstract | Full Text S100A2 is a BRCA1/p63 coregulated tumour suppressor gene with roles in the regulation of mutant p53 stability N E Buckley, Z D'Costa, M Kaminska and P B Mullan Cell Death Dis 2014 5: e1070; 10.1038/cddis.2014.31 Abstract | Full Text Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition P Chaudhry, F Fabi, M Singh, S Parent, V Leblanc and E Asselin Cell Death Dis 2014 5: e1044; 10.1038/cddis.2014.7 Abstract | Full Text A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways J Cheng, Y-H Fan, X Xu, H Zhang, J Dou, Y Tang, X Zhong, Y Rojas, Y Yu, Y Zhao, S A Vasudevan, H Zhang, J G Nuchtern, E S Kim, X Chen, F Lu and J Yang Cell Death Dis 2014 5: e1079; 10.1038/cddis.2014.54 Abstract | Full Text Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer S De Summa, R Pinto, B Pilato, D Sambiasi, L Porcelli, G Guida, E Mattioli, A Paradiso, G Merla, L Micale, P De Nittis and S Tommasi Cell Death Dis 2014 5: e1076; 10.1038/cddis.2014.30 Abstract | Full Text Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma M G Dionyssiou, S Ehyai, E Avrutin, M K Connor and J C McDermott Cell Death Dis 2014 5: e1094; 10.1038/cddis.2014.58 Abstract | Full Text DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury R K Dongworth, U A Mukherjee, A R Hall, R Astin, S-B Ong, Z Yao, A Dyson, G Szabadkai, S M Davidson, D M Yellon and D J Hausenloy Cell Death Dis 2014 5: e1082; 10.1038/cddis.2014.41 Abstract | Full Text Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling Y Feng, C Ke, Q Tang, H Dong, X Zheng, W Lin, J Ke, J Huang, S-CJ Yeung and H Zhang Cell Death Dis 2014 5: e1088; 10.1038/cddis.2014.59 Abstract | Full Text S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis M Fröhlich, B Dejanovic, H Kashkar, G Schwarz and S Nussberger Cell Death Dis 2014 5: e1057; 10.1038/cddis.2014.17 Abstract | Full Text The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion M Garg, N Ramdas, M Vijayalakshmi, G V Shivashankar and A Sarin Cell Death Dis 2014 5: e1058; 10.1038/cddis.2014.20 Abstract | Full Text Early and sustained altered expression of aging-related genes in young 3xTg-AD mice V Gatta, M D'Aurora, A Granzotto, L Stuppia and S L Sensi Cell Death Dis 2014 5: e1054; 10.1038/cddis.2014.11 Abstract | Full Text Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence D Gitenay, C Wiel, H Lallet-Daher, D Vindrieux, S Aubert, L Payen, H Simonnet and D Bernard Cell Death Dis 2014 5: e1089; 10.1038/cddis.2014.63 Abstract | Full Text MYCN gene expression is required for the onset of the differentiation programme in neuroblastoma cells L Guglielmi, C Cinnella, M Nardella, G Maresca, A Valentini, D Mercanti, A Felsani and I D'Agnano Cell Death Dis 2014 5: e1081; 10.1038/cddis.2014.42 Abstract | Full Text MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells M He, Y Lu, S Xu, L Mao, L Zhang, W Duan, C Liu, H Pi, Y Zhang, M Zhong, Z Yu and Z Zhou Cell Death Dis 2014 5: e1090; 10.1038/cddis.2014.60 Abstract | Full Text Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells Y-C Hsu, M-J Chen and T-Y Huang Cell Death Dis 2014 5: e1087; 10.1038/cddis.2014.22 Abstract | Full Text Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients Y A Ito, I S Goping, F Berry and M A Walter Cell Death Dis 2014 5: e1069; 10.1038/cddis.2014.8 Abstract | Full Text Nonthermal plasma induces head and neck cancer cell death: the potential involvement of mitogen-activated protein kinase-dependent mitochondrial reactive oxygen species S U Kang, J-H Cho, J W Chang, Y S Shin, K I Kim, J K Park, S S Yang, J-S Lee, E Moon, K Lee and C-H Kim Cell Death Dis 2014 5: e1056; 10.1038/cddis.2014.33 Abstract | Full Text High-dose of vitamin C supplementation reduces amyloid plaque burden and ameliorates pathological changes in the brain of 5XFAD mice S-Y Kook, K-M Lee, Y Kim, M-Y Cha, S Kang, S H Baik, H Lee, R Park and I Mook-Jung Cell Death Dis 2014 5: e1083; 10.1038/cddis.2014.26 Abstract | Full Text An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity U Krause, D M Ryan, B H Clough and C A Gregory Cell Death Dis 2014 5: e1093; 10.1038/cddis.2014.67 Abstract | Full Text miR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation J Kureel, M Dixit, A M Tyagi, M N Mansoori, K Srivastava, A Raghuvanshi, R Maurya, R Trivedi, A Goel and D Singh Cell Death Dis 2014 5: e1050; 10.1038/cddis.2014.4 Abstract | Full Text Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma T W Laetsch, X Liu, A Vu, M Sliozberg, M Vido, O U Elci, K C Goldsmith and M D Hogarty Cell Death Dis 2014 5: e1072; 10.1038/cddis.2014.40 Abstract | Full Text Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria K Liu, Y Shi, X H Guo, Y B Ouyang, S S Wang, D J Liu, A N Wang, N Li and D X Chen Cell Death Dis 2014 5: e1078; 10.1038/cddis.2014.51 Abstract | Full Text Akt and mTOR mediate programmed necrosis in neurons Q Liu, J Qiu, M Liang, J Golinski, K van Leyen, J E Jung, Z You, E H Lo, A Degterev and M J Whalen Cell Death Dis 2014 5: e1084; 10.1038/cddis.2014.69 Abstract | Full Text The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1 M G Mathieu, A K Miles, M Ahmad, M E Buczek, A G Pockley, R C Rees and T Regad Cell Death Dis 2014 5: e1061; 10.1038/cddis.2014.29 Abstract | Full Text Knockdown of BAG3 induces epithelial–mesenchymal transition in thyroid cancer cells through ZEB1 activation X Meng, D-H Kong, N Li, Z-H Zong, B-Q Liu, Z-X Du, Y Guan, L Cao and H-Q Wang Cell Death Dis 2014 5: e1092; 10.1038/cddis.2014.32 Abstract | Full Text Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L) K-j Min, B R Seo, Y C Bae, Y H Yoo and T K Kwon Cell Death Dis 2014 5: e1063; 10.1038/cddis.2014.35 Abstract | Full Text Necroptosis induced by RIPK3 requires MLKL but not Drp1 D M Moujalled, W D Cook, J M Murphy and D L Vaux Cell Death Dis 2014 5: e1086; 10.1038/cddis.2014.18 Abstract | Full Text Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer W Nakajima, M A Hicks, N Tanaka, G W Krystal and H Harada Cell Death Dis 2014 5: e1052; 10.1038/cddis.2014.6 Abstract | Full Text Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism S P Narayanan, Z Xu, N Putluri, A Sreekumar, T Lemtalsi, R W Caldwell and R B Caldwell Cell Death Dis 2014 5: e1075; 10.1038/cddis.2014.23 Abstract | Full Text Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc L Patrussi, N Capitani, E Cannizzaro, F Finetti, O M Lucherini, P G Pelicci and C T Baldari Cell Death Dis 2014 5: e1068; 10.1038/cddis.2014.44 Abstract | Full Text TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain A Pla, M Pascual, J Renau-Piqueras and C Guerri Cell Death Dis 2014 5: e1066; 10.1038/cddis.2014.46 Abstract | Full Text Impact of human papilloma virus infection on the response of head and neck cancers to anti-epidermal growth factor receptor antibody therapy M Pogorzelski, S Ting, T C Gauler, F Breitenbuecher, I Vossebein, S Hoffarth, J Markowetz, S Lang, C Bergmann, S Brandau, J A Jawad, K W Schmid, M Schuler and S Kasper Cell Death Dis 2014 5: e1091; 10.1038/cddis.2014.62 Abstract | Full Text Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure R C Poulsen, H J Knowles, A J Carr and P A Hulley Cell Death Dis 2014 5: e1074; 10.1038/cddis.2014.52 Abstract | Full Text HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype Y Qin, Y Chen, W Wang, Z Wang, G Tang, P Zhang, Z He, Y Liu, S-M Dai and Q Shen Cell Death Dis 2014 5: e1077; 10.1038/cddis.2014.48 Abstract | Full Text Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest S Raz, D Sheban, N Gonen, M Stark, B Berman and Y G Assaraf Cell Death Dis 2014 5: e1067; 10.1038/cddis.2014.39 Abstract | Full Text MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2 Q Ruan, P Wang, T Wang, J Qi, M Wei, S Wang, T Fan, D Johnson, X Wan, W Shi, H Sun and Y H Chen Cell Death Dis 2014 5: e1095; 10.1038/cddis.2014.47 Abstract | Full Text Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells K Shi, J An, L Shan, Q Jiang, F Li, Y Ci, P Wu, J Duan, K Hui, Y Yang and C Xu Cell Death Dis 2014 5: e1071; 10.1038/cddis.2014.34 Abstract | Full Text Mahogunin-mediated α-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation D Srivastava and O Chakrabarti Cell Death Dis 2014 5: e1064; 10.1038/cddis.2014.1 Abstract | Full Text A functional role for Smad7 in sustaining colon cancer cell growth and survival C Stolfi, V De Simone, A Colantoni, E Franzè, E Ribichini, M C Fantini, R Caruso, I Monteleone, G S Sica, P Sileri, T T MacDonald, F Pallone and G Monteleone Cell Death Dis 2014 5: e1073; 10.1038/cddis.2014.49 Abstract | Full Text Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells Y Teng, M Gao, J Wang, Q Kong, H Hua, T Luo and Y Jiang Cell Death Dis 2014 5: e1060; 10.1038/cddis.2014.24 Abstract | Full Text Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer R C Turkington, D B Longley, W L Allen, L Stevenson, K McLaughlin, P D Dunne, J K Blayney, M Salto-Tellez, S Van Schaeybroeck and P G Johnston Cell Death Dis 2014 5: e1046; 10.1038/cddis.2014.10 Abstract | Full Text miRNA let-7e targeting MMP9 is involved in adipose-derived stem cell differentiation toward epithelia M Ventayol, J L Viñas, A Sola, M Jung, B Brüne, F Pi, C Mastora and G Hotter Cell Death Dis 2014 5: e1048; 10.1038/cddis.2014.2 Abstract | Full Text Uracil DNA glycosylase (UNG) loss enhances DNA double strand break formation in human cancer cells exposed to pemetrexed L D Weeks, G E Zentner, P C Scacheri and S L Gerson Cell Death Dis 2014 5: e1045; 10.1038/cddis.2013.477 Abstract | Full Text The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells P Wu, K J Shi, J J An, Y L Ci, F Li, K Y Hui, Y Yang and C M Xu Cell Death Dis 2014 5: e1085; 10.1038/cddis.2014.13 Abstract | Full Text TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer W Xu, S Wang, Q Chen, Y Zhang, P Ni, X Wu, J Zhang, F Qiang, A Li, O D Røe, S Xu, M Wang, R Zhang and J Zhou Cell Death Dis 2014 5: e1055; 10.1038/cddis.2014.27 Abstract | Full Text PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons D-J Yang, X-L Wang, A Ismail, C J Ashman, C F Valori, G Wang, S Gao, A Higginbottom, P G Ince, M Azzouz, J Xu, P J Shaw and K Ning Cell Death Dis 2014 5: e1096; 10.1038/cddis.2014.55 Abstract | Full Text Suppression of tumor angiogenesis by targeting the protein neddylation pathway W-T Yao, J-F Wu, G-Y Yu, R Wang, K Wang, L-H Li, P Chen, Y-N Jiang, H Cheng, H W Lee, J Yu, H Qi, X-J Yu, P Wang, Y-W Chu, M Yang, Z-C Hua, H-Q Ying, R M Hoffman, L S Jeong and L-J Jia Cell Death Dis 2014 5: e1059; 10.1038/cddis.2014.21 Abstract | Full Text Galectin-1 stimulates motility of human umbilical cord blood-derived mesenchymal stem cells by downregulation of smad2/3-dependent collagen 3/5 and upregulation of NF-κB-dependent fibronectin/laminin 5 expression S P Yun, S-J Lee, Y H Jung and H J Han Cell Death Dis 2014 5: e1049; 10.1038/cddis.2014.3 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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