Scientific Reports Table of Contents e-alert: 8 July 2014

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08 July 2014      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports             Jump to the content that matters to you ▼ Biological Sciences   ▼ Chemical Sciences   ▼ Physical Sciences   ▼ Earth & Environmental Sciences   ▼ Health Sciences               Biological Sciences ▲ top               ERRATUM: Kinetic behaviour of the cells touching substrate: the interfacial stiffness guides cell spreading ▶     Jianjun Li, Dong Han, Ya-Pu Zhao                 CORRIGENDUM: Src tyrosine kinase signaling antagonizes nuclear localization of FOXO and inhibits its transcription factor activity ▶     Margret H. Bülow, Torsten R. Bülow, Michael Hoch et al.                 A novel two-step sintering for nano-hydroxyapatite scaffolds for bone tissue engineering ▶     Pei Feng, Man Niu, Chengde Gao et al.     In this study, nano-hydroxyapatite scaffolds with high mechanical strength and an interconnected porous structure were prepared using NTSS for the first time. The first step was …             Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance ▶     Yi Chung Chen, Chin Lin Wong, Frederico Muzzi et al.     Fusarium oxysporum is a root-infecting fungal pathogen that causes wilt disease on a broad range of plant species, including Arabidopsis thaliana. Investigation of the defense …             Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1) ▶     Bart J. G. Broeckx, Frank Coopman, Geert E. C. Verhoeven et al.     Whole exome sequencing is a technique that aims to selectively sequence all exons of protein-coding genes. A canine whole exome sequencing enrichment kit was designed based on the …             Environmental variability and biodiversity of megabenthos on the Hebrides Terrace Seamount (Northeast Atlantic) ▶     Lea-Anne Henry, Johanne Vad, Helen S. Findlay et al.     We present the first remotely operated vehicle investigation of megabenthic communities (1004–1695 m water depth) on the Hebrides Terrace Seamount (Northeast Atlantic). …             WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes ▶     Fei Wang, Liang Zhang, Guang-Li Zhang et al.     Prior to their fertilization, oocytes undergo asymmetric division, which is regulated by actin filaments. Recently, WASH complex were identified as actin nucleation promoting …             Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish ▶     Yanyan Shi, Yu Zhang, Fangying Zhao et al.     The mechanisms underlying gut development, especially peristalsis, are widely studied topics. However, the causes of gut peristalsis-related diseases, especially Opioid-Induced …             Activation of the germ-cell potential of human bone marrow-derived cells by a chemical carcinogen ▶     Chunfang Liu, Zhan Ma, Songtao Xu et al.     Embryonic/germ cell traits are common in malignant tumors and are thought to be involved in malignant tumor behaviors. The reasons why tumors show strong embryonic/germline traits …             Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model ▶     Jia Xiao, Feiyue Xing, Jie Huo et al.     This study aimed to investigate the possible therapeutic effects and active components of Lycium barbarum polysaccharides (LBP) on a high fat diet-induced NASH rat model. We …             TR-FRET Assays of Huntingtin Protein Fragments Reveal Temperature and PolyQ Length-Dependent Conformational Changes ▶     Xiaotian Cui, Qingnan Liang, Yijian Liang et al.     Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) technology is a widely used immunoassay that enables high-throughput quantitative measurements of proteins of …             TGF-β1, IL-6, and TNF-α in Bronchoalveolar Lavage Fluid: Useful Markers for Lung Cancer? ▶     Zhongbo Chen, Zhiwei Xu, Shifang Sun et al.     Changes of cytokines in bronchoalveolar lavage fluid (BALF) reflect immunologic reactions of the lung in pulmonary malignancies. Detection of biomarkers in BALF might serve as an …             Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance ▶     Hongbiao Jing, Guoming Zhang, Lingsheng Meng et al.     Gankyrin is an important oncoprotein that is overexpressed in human hepatocellular carcinoma (HCC). However, the gradual alteration of Gankyrin in successive stages during human …             CORRIGENDUM: Dissecting the cell to nucleus, perinucleus and cytosol ▶     Tattym E. Shaiken, Antone R. Opekun                 Fluorescence detection of cellular nucleotide excision repair of damaged DNA ▶     Tatsuya Toga, Isao Kuraoka, Shun Watanabe et al.     To maintain genetic integrity, ultraviolet light-induced photoproducts in DNA must be removed by the nucleotide excision repair (NER) pathway, which is initiated by damage …             An early origin for detailed perception in Autism Spectrum Disorder: biased sensitivity for high-spatial frequency information. ▶     Luc Kéïta, Jacalyn Guy, Claude Berthiaume et al.     Autistics demonstrate superior performances on several visuo-spatial tasks where local or detailed information processing is advantageous. Altered spatial filtering properties at …             Computational prediction of microRNA networks incorporating environmental toxicity and disease etiology ▶     Jie Li, Zengrui Wu, Feixiong Cheng et al.     MicroRNAs (miRNAs) play important roles in multiple biological processes and have attracted much scientific attention recently. Their expression can be altered by environmental …             Delayed and time-cumulative toxicity of imidacloprid in bees, ants and termites ▶     Gary Rondeau, Francisco Sánchez-Bayo, Henk A. Tennekes et al.     Imidacloprid, one of the most commonly used insecticides, is highly toxic to bees and other beneficial insects. The regulatory challenge to determine safe levels of residual …             A design principle underlying the paradoxical roles of E3 ubiquitin ligases ▶     Daewon Lee, Minjin Kim, Kwang-Hyun Cho     E3 ubiquitin ligases are important cellular components that determine the specificity of proteolysis in the ubiquitin-proteasome system. However, an increasing number of studies …             Similar morphological and molecular signatures shared by female and male germline stem cells ▶     Wenhai Xie, Hu Wang, Ji Wu     The existence of mammalian female germline stem cells (FGSCs) indicates that mammalian ovaries possess germline stem cells analogous to testis, and continue to produce gametes …             Genomic methylation patterns in archaeological barley show de-methylation as a time-dependent diagenetic process ▶     Oliver Smith, Alan J. Clapham, Pam Rose et al.     Genomic methylation is variable under biotic and abiotic stresses in plants. In particular, viral infection is thought to significantly increase genomic methylation with …             Stress and self-efficacy predict psychological adjustment at diagnosis of prostate cancer ▶     Ruth Curtis, AnnMarie Groarke, Frank Sullivan     Prostate cancer is the most frequently non-skin cancer diagnosed among men. Diagnosis, a significant burden, generates many challenges which impact on emotional adjustment and so …             Distinguishing between cancer cell differentiation and resistance induced by all-trans retinoic acid using transcriptional profiles and functional pathway analysis ▶     Song-Mei Liu, Weiping Chen, Jin Wang     All-trans retinoic acid (ATRA) induces differentiation in various cell types and has been investigated extensively for its effective use in cancer prevention and treatment. …             Wide-field imaging and flow cytometric analysis of cancer cells in blood by fluorescent nanodiamond labeling and time gating ▶     Yuen Yung Hui, Long-Jyun Su, Oliver Yenjyh Chen et al.     Nanodiamonds containing high density ensembles of negatively charged nitrogen-vacancy (NV−) centers are promising fluorescent biomarkers due to their excellent photostability and …             Opinion Dynamics and Influencing on Random Geometric Graphs ▶     Weituo Zhang, Chjan C. Lim, G. Korniss et al.     We investigate the two-word Naming Game on two-dimensional random geometric graphs. Studying this model advances our understanding of the spatial distribution and propagation of …             Increased leukemia-associated gene expression in benzene-exposed workers ▶     Keqiu Li, Yaqing Jing, Caihong Yang et al.     Long-term exposure to benzene causes several adverse health effects, including an increased risk of acute myeloid leukemia. This study was to identify genetic alternations …             Molecular phylogeny of Orthetrum dragonflies reveals cryptic species of Orthetrum pruinosum ▶     Hoi Sen Yong, Phaik-Eem Lim, Ji Tan et al.     Dragonflies of the genus Orthetrum are members of the suborder Anisoptera, family Libellulidae. There are species pairs whose members are not easily separated from each other by …             Inhibition of cytomegalovirus infection and photothermolysis of infected cells using bioconjugated gold nanoparticles ▶     Bernadette M. DeRussy, Madeline A. Aylward, Zhen Fan et al.     Human cytomegalovirus (CMV) is a herpesvirus that causes major health problems in neonates as well as in immunocompromised individuals. At present, a vaccine is not available for …             Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule ▶     Tae-Wook Kang, Soon Won Choi, Se-Ran Yang et al.     Glioblastoma multiforme is the most common malignant brain tumor in adults, with an average survival of less than one year due to its resistance to therapy. Recent studies …             Deep rooting conferred by DEEPER ROOTING 1 enhances rice yield in paddy fields ▶     Yumiko Arai-Sanoh, Toshiyuki Takai, Satoshi Yoshinaga et al.     To clarify the effect of deep rooting on grain yield in rice (Oryza sativa L.) in an irrigated paddy field with or without fertilizer, we used the shallow-rooting IR64 and the …             Horizontal gene transfer of a bacterial insect toxin gene into the Epichloë fungal symbionts of grasses ▶     Karen V. Ambrose, Albrecht M. Koppenhöfer, Faith C. Belanger     Horizontal gene transfer is recognized as an important factor in genome evolution, particularly when the newly acquired gene confers a new capability to the recipient species. We …             Brain Network Informed Subject Community Detection In Early-Onset Schizophrenia ▶     Zhi Yang, Yong Xu, Ting Xu et al.     Early-onset schizophrenia (EOS) offers a unique opportunity to study pathophysiological mechanisms and development of schizophrenia. Using 26 drug-naïve, first-episode EOS …             Fetal and adult fibroblasts display intrinsic differences in tendon tissue engineering and regeneration ▶     Qiao-Mei Tang, Jia Lin Chen, Wei Liang Shen et al.     Injured adult tendons do not exhibit optimal healing through a regenerative process, whereas fetal tendons can heal in a regenerative fashion without scar formation. Hence, we …             Combining colour and temperature: A blue object is more likely to be judged as warm than a red object ▶     Hsin-Ni Ho, Daisuke Iwai, Yuki Yoshikawa et al.     It is commonly believed that reddish colour induces warm feelings while bluish colour induces cold feelings. We, however, demonstrate an opposite effect when the temperature …             Developmental tuning of reflexive attentional effect to biological motion cues ▶     Jing Zhao, Li Wang, Ying Wang et al.     The human visual system is extremely sensitive to the direction information retrieved from biological motion. In the current study, we investigate the functional impact of this …             Mice Deficient in Intestinal Epithelium Cytochrome P450 Reductase are Prone to Acute Toxin-induced Mucosal Damage ▶     Sarita Ahlawat, Fang Xie, Yi Zhu et al.     Cytochrome P450 (P450) enzymes are a superfamily of heme-containing enzymes involved in the metabolism of various endogenous compounds, including retinoids, glucocorticoids, and …             EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression ▶     Huihua Zhang, Xiaojia Chen, Jiakang Wang et al.     Early growth response 1 (EGR1) is a multifunctional transcription factor; Positive and negative functions of EGR1 in various tumors rely on the integrated functions of various …             Clinical implication of changes in serum adiponectin in patients with hepatogenic diabetes ▶     Zhongying Bao, Xiaodong Yuan, Shuhong Duan et al.     Adiponectin is a protein hormone that modulates glucose metabolism and fatty acid oxidation. We explored the clinical implication of serum adiponectin in hepatogenic diabetes. …             Protective Effect of Dl-3n-butylphthalide on Learning and Memory Impairment Induced by Chronic Intermittent Hypoxia-Hypercapnia Exposure ▶     Jing-jing Min, Xin-long Huo, ling-yun Xiang et al.     Cognitive impairment is a common finding in patients with chronic obstructive pulmonary disease (COPD), but little attention has been focused on therapeutic intervention for this …             The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ42 internalization ▶     Bianca Da Costa Dias, Katarina Jovanovic, Danielle Gonsalves et al.     Neuronal loss is a major neuropathological hallmark of Alzheimer's disease (AD). The associations between soluble Aβ oligomers and cellular components cause this neurotoxicity. …             Ancient harbour infrastructure in the Levant: tracking the birth and rise of new forms of anthropogenic pressure ▶     Nick Marriner, Christophe Morhange, David Kaniewski et al.     Beirut, Sidon and Tyre were major centres of maritime trade from the Bronze Age onwards. This economic prosperity generated increased pressures on the local environment, through …             Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition ▶     Tao Chen, Jing Wang, Chenhui Li et al.     Evidence suggests that thrombin, a blood coagulation serine protease, mediates neuronal injury in experimental cerebral ischemia. Here, we test the hypothesis that nafamostat …             Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses ▶     Tomoko Kobayashi, Junko S. Takeuchi, Fengrong Ren et al.     Primate lentiviruses including human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency viruses (SIVs) evolved through the acquisition of antagonists against …             Determination of Arabidopsis thaliana telomere length by PCR ▶     María I. Vaquero-Sedas, Miguel A. Vega-Palas     In humans, telomere length studies have acquired great relevance because the length of telomeres has been related to natural processes like disease, aging and cancer. However, …             Cooperation with both synergistic and local interactions can be worse than each alone ▶     Aming Li, Bin Wu, Long Wang     Cooperation is ubiquitous ranging from multicellular organisms to human societies. Population structures indicating individuals' limited interaction ranges are crucial to …             PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis ▶     Menghan Liu, Magdalene K. Montgomery, Corrine E. Fiveash et al.     Excess dietary lipid generally leads to fat deposition and impaired glucose homeostasis, but consumption of fish oil (FO) alleviates many of these detrimental effects. The …             Phosphines are ribonucleotide reductase reductants that act via C-terminal cysteines similar to thioredoxins and glutaredoxins ▶     Vladimir Domkin, Andrei Chabes     Ribonucleotide reductases (RNRs) catalyze the formation of 2′-deoxyribonucleotides. Each polypeptide of the large subunit of eukaryotic RNRs contains two redox-active cysteine …             NF-κB-to-AP-1 Switch: A Mechanism Regulating Transition From Endothelial Barrier Injury to Repair in Endotoxemic Mice ▶     Gang Liu, Xiaobing Ye, Edmund J. Miller et al.     Endothelial barrier disruption is a hallmark of multiple organ injury (MOI). However, mechanisms governing the restoration of endothelial barrier function are poorly understood. …             Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival ▶     Silke Fuchs, Ermelinda Rende, Andrea Crisanti et al.     Insecticide resistance amongst disease vectors is a growing problem and novel compounds are needed. Biogenic amines are important for neurotransmission and we have recently shown …             Cytotoxic activity of acyl phloroglucinols isolated from the leaves of Eucalyptus cinerea F. Muell. ex Benth. cultivated in Egypt ▶     Fathy M. Soliman, Magda M. Fathy, Maha M. Salama et al.     Two acyl phloroglucinol compounds namely; Sideroxylonal B (1) and Macrocarpal A (2) were isolated from the Sideroxylonal-Rich Extract (SRE) of the juvenile leaves of Eucalyptus …             A genetic screen for suppressors of a hypomorphic allele of Arabidopsis ARGONAUTE1 ▶     Rosa Micol-Ponce, Verónica Aguilera, María Rosa Ponce     ARGONAUTE1 (AGO1) encodes a key component of the complexes mediating microRNA (miRNA) function in Arabidopsis. To study the regulation, action and interactions of AGO1, we …             Ontogenesis of the HPI axis and molecular regulation of the cortisol stress response during early development in Dicentrarchus labrax. ▶     A. Tsalafouta, N. Papandroulakis, M. Gorissen et al.     The cortisol stress response and the molecular programming of the corticoid axis were characterized for the first time during early ontogeny in a Mediterranean marine teleost, the …             Effects of hydrogen-rich water on aging periodontal tissues in rats ▶     Takaaki Tomofuji, Yuya Kawabata, Kenta Kasuyama et al.     Oxidative damage is involved in age-related inflammatory reactions. The anti-oxidative effects of hydrogen-rich water suppress oxidative damage, which may aid in inhibiting …             Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells ▶     Betty Yuen Kwan Law, Wai Kit Chan, Su Wei Xu et al.     Resistance of cancer cells to chemotherapy is a significant problem in oncology, and the development of sensitising agents or small-molecules with new mechanisms of action to kill …             Effects of vegetative propagule pressure on the establishment of an introduced clonal plant, Hydrocotyle vulgaris ▶     Ruihua Liu, Qiuwen Chen, Bicheng Dong et al.     Some introduced clonal plants spread mainly by vegetative (clonal) propagules due to the absence of sexual reproduction in the introduced range. Propagule pressure (i.e. total …             Cisplatin modulates B-cell translocation gene 2 to attenuate cell proliferation of prostate carcinoma cells in both p53-dependent and p53-independent pathways ▶     Kun-Chun Chiang, Ke-Hung Tsui, Li-Chuan Chung et al.     Cisplatin is a widely used anti-cancer drug. The B-cell translocation gene 2 (BTG2) is involved in the cell cycle transition regulation. We evaluated the cisplatin effects on …             Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF ▶     Yoshiyuki Yamazaki, Yukihiko Hirai, Koichi Miyake et al.     Enzyme replacement via the cerebrospinal fluid (CSF) has been shown to ameliorate neurological symptoms in model animals with neuropathic metabolic disorders. Gene therapy via the …             An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E-/- mice ▶     Nan Peng, Ning Meng, ShengQing Wang et al.     Oxidized low-density lipoprotein (oxLDL) inhibits mammalian target of rapamycin (mTOR) and induces autophagy and apoptosis in vascular endothelial cells (VECs) that play very …             A ‘Clicked’ Tetrameric Hydroxamic Acid Glycopeptidomimetic Antagonizes Sugar-Lectin Interactions On The Cellular Level ▶     Hai-Lin Zhang, Yi Zang, Juan Xie et al.     A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent ‘click …             Graphene-protected copper and silver plasmonics ▶     V. G. Kravets, R. Jalil, Y.-J. Kim et al.     Plasmonics has established itself as a branch of physics which promises to revolutionize data processing, improve photovoltaics, and increase sensitivity of bio-detection. A …             Tumor regression achieved by encapsulating a moderately soluble drug into a polymeric thermogel ▶     Tianyuan Ci, Liang Chen, Lin Yu et al.     For cancer chemotherapy, a tumor regression without any surgical resection and severe side effects is greatly preferred to merely slowing down the growth of tumors. Here, we …                 Nature Medicine and Helmholtz Zentrum München present: 2nd Annual Helmholtz-Nature Medicine Diabetes Conference September 21-23, 2014 Lenbach Palais Rilano No.6 Munich, Germany Click here for more information or to register for this conference today!          Chemical Sciences ▲ top               One-step shell polymerization of inorganic nanoparticles and their applications in SERS/nonlinear optical imaging, drug delivery, and catalysis ▶     Tzu-Ming Liu, Jiashing Yu, C. Allen Chang et al.     Surface functionalized nanoparticles have found their applications in several fields including biophotonics, nanobiomedicine, biosensing, drug delivery, and catalysis. Quite …             Multifunctional Interface Modification of Energy Relay Dye in Quasi-solid Dye-sensitized Solar Cells ▶     Rui Gao, Yixiu Cui, Xiaojiang Liu et al.     In this paper, 4-(dicyanomethylene)-2-t-butyl-6(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB) has been used in interface modification of dye-sensitized solar cells (DSCs) …             Laser Actuation of Cantilevers for Picometre Amplitude Dynamic Force Microscopy ▶     Drew R. Evans, Ponlawat Tayati, Hongjie An et al.     As nanoscale and molecular devices become reality, the ability to probe materials on these scales is increasing in importance. To address this, we have developed a dynamic force …             Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's saliva samples using stochastic microsensors ▶     Raluca-Ioana Stefan-van Staden, Livia Alexandra Gugoaşă, Bogdan Calenic et al.     Stochastic microsensors based on diamond paste and three types of electroactive materials (maltodextrin (MD), α-cyclodextrin (α-CD) and 5,10,15,20-tetraphenyl-21H,23H porphyrin …             A ‘Clicked’ Tetrameric Hydroxamic Acid Glycopeptidomimetic Antagonizes Sugar-Lectin Interactions On The Cellular Level ▶     Hai-Lin Zhang, Yi Zang, Juan Xie et al.     A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent ‘click …                     Physical Sciences ▲ top               Demonstration of higher colour response with ambient refractive index in Papilio blumei as compared to Morphorhetenor ▶     Wanlin Wang, Wang Zhang, Xiaotian Fang et al.     Multilayer structures are known to produce vivid iridescent colouration in many butterflies. Morpho butterflies are well known for their high reflectance, which appears to remain …             One-step shell polymerization of inorganic nanoparticles and their applications in SERS/nonlinear optical imaging, drug delivery, and catalysis ▶     Tzu-Ming Liu, Jiashing Yu, C. Allen Chang et al.     Surface functionalized nanoparticles have found their applications in several fields including biophotonics, nanobiomedicine, biosensing, drug delivery, and catalysis. Quite …             Graphene/Si CMOS Hybrid Hall Integrated Circuits ▶     Le Huang, Huilong Xu, Zhiyong Zhang et al.     Graphene/silicon CMOS hybrid integrated circuits (ICs) should provide powerful functions which combines the ultra-high carrier mobility of graphene and the sophisticated functions …             ERRATUM: Kinetic behaviour of the cells touching substrate: the interfacial stiffness guides cell spreading ▶     Jianjun Li, Dong Han, Ya-Pu Zhao                 Crack Propagation in Bamboo's Hierarchical Cellular Structure ▶     Meisam K. Habibi, Yang Lu     Bamboo, as a natural hierarchical cellular material, exhibits remarkable mechanical properties including excellent flexibility and fracture toughness. As far as bamboo as a …             Room temperature electrical spin injection into GaAs by an oxide spin injector ▶     Shwetha G. Bhat, P. S. Anil Kumar     Spin injection, manipulation and detection are the integral parts of spintronics devices and have attracted tremendous attention in the last decade. It is necessary to judiciously …             Electronic correlations determine the phase stability of iron up to the melting temperature ▶     I. Leonov, A. I. Poteryaev, Yu. N. Gornostyrev et al.     We present theoretical results on the high-temperature phase stability and phonon spectra of paramagnetic bcc iron which explicitly take into account many-body effects. Several …             Spectromicroscopy of electronic phase separation in KxFe2−ySe2 superconductor ▶     M. Bendele, A. Barinov, B. Joseph et al.     Structural phase separation in AxFe2−ySe2 system has been studied by different experimental techniques, however, it should be important to know how the electronic uniformity is …             High-performance graphene-quantum-dot photodetectors ▶     Chang Oh Kim, Sung Won Hwang, Sung Kim et al.     Graphene quantum dots (GQDs) have received much attention due to their novel phenomena of charge transport and light absorption/emission. The optical transitions are known to be …             Laser Actuation of Cantilevers for Picometre Amplitude Dynamic Force Microscopy ▶     Drew R. Evans, Ponlawat Tayati, Hongjie An et al.     As nanoscale and molecular devices become reality, the ability to probe materials on these scales is increasing in importance. To address this, we have developed a dynamic force …             Opinion Dynamics and Influencing on Random Geometric Graphs ▶     Weituo Zhang, Chjan C. Lim, G. Korniss et al.     We investigate the two-word Naming Game on two-dimensional random geometric graphs. Studying this model advances our understanding of the spatial distribution and propagation of …             All-optical differential equation solver with constant-coefficient tunable based on a single microring resonator ▶     Ting Yang, Jianji Dong, Liangjun Lu et al.     Photonic integrated circuits for photonic computing open up the possibility for the realization of ultrahigh-speed and ultra wide-band signal processing with compact size and low …             Photoluminescence quenching in gold - MoS2 hybrid nanoflakes ▶     Udai Bhanu, Muhammad R. Islam, Laurene Tetard et al.     Achieving tunability of two dimensional (2D) transition metal dichalcogenides (TMDs) functions calls for the introduction of hybrid 2D materials by means of localized interactions …             Multifunctional Interface Modification of Energy Relay Dye in Quasi-solid Dye-sensitized Solar Cells ▶     Rui Gao, Yixiu Cui, Xiaojiang Liu et al.     In this paper, 4-(dicyanomethylene)-2-t-butyl-6(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB) has been used in interface modification of dye-sensitized solar cells (DSCs) …             An opto-magneto-mechanical quantum interface between distant superconducting qubits ▶     Keyu Xia, Michael R. Vanner, Jason Twamley     A quantum internet, where widely separated quantum devices are coherently connected, is a fundamental vision for local and global quantum information networks and processing. …             Magnetic field and temperature sensing with atomic-scale spin defects in silicon carbide ▶     H. Kraus, V. A. Soltamov, F. Fuchs et al.     Quantum systems can provide outstanding performance in various sensing applications, ranging from bioscience to nanotechnology. Atomic-scale defects in silicon carbide are very …             Wide-field imaging and flow cytometric analysis of cancer cells in blood by fluorescent nanodiamond labeling and time gating ▶     Yuen Yung Hui, Long-Jyun Su, Oliver Yenjyh Chen et al.     Nanodiamonds containing high density ensembles of negatively charged nitrogen-vacancy (NV−) centers are promising fluorescent biomarkers due to their excellent photostability and …             Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's saliva samples using stochastic microsensors ▶     Raluca-Ioana Stefan-van Staden, Livia Alexandra Gugoaşă, Bogdan Calenic et al.     Stochastic microsensors based on diamond paste and three types of electroactive materials (maltodextrin (MD), α-cyclodextrin (α-CD) and 5,10,15,20-tetraphenyl-21H,23H porphyrin …             Searching for superspreaders of information in real-world social media ▶     Sen Pei, Lev Muchnik, José S. Andrade, Jr. et al.     A number of predictors have been suggested to detect the most influential spreaders of information in online social media across various domains such as Twitter or Facebook. In …             Realization of Tunable Photonic Spin Hall Effect by Tailoring the Pancharatnam-Berry Phase ▶     Xiaohui Ling, Xinxing Zhou, Weixing Shu et al.     Recent developments in the field of photonic spin Hall effect (SHE) offer new opportunities for advantageous measurement of the optical parameters (refractive index, thickness, …             How congestion shapes cities: from mobility patterns to scaling ▶     Rémi Louf, Marc Barthelemy     The recent availability of data for cities has allowed scientists to exhibit scalings which present themselves in the form of a power-law dependence on population of various …             Encapsulated Annealing: Enhancing the Plasmon Quality Factor in Lithographically–Defined Nanostructures ▶     Michel Bosman, Lei Zhang, Huigao Duan et al.     Lithography provides the precision to pattern large arrays of metallic nanostructures with varying geometries, enabling systematic studies and discoveries of new phenomena in …             Mechanical Resonances of Helically Coiled Carbon Nanowires ▶     D. Saini, H. Behlow, R. Podila et al.     Despite their wide spread applications, the mechanical behavior of helically coiled structures has evaded an accurate understanding at any length scale (nano to macro) mainly due …             Extraordinary Second Harmonic Generation in Tungsten Disulfide Monolayers ▶     Corey Janisch, Yuanxi Wang, Ding Ma et al.     We investigate Second Harmonic Generation (SHG) in monolayer WS2 both deposited on a SiO2/Si substrate or suspended using transmission electron microscopy grids. We find unusually …             Realizing Synchronous Energy Harvesting and Ion Separation with Graphene Oxide Membranes ▶     Pengzhan Sun, Feng Zheng, Miao Zhu et al.     A synchronous ion separation and electricity generation process has been developed using G-O membranes. In addition to the size effect proposed prevsiouly, the separation of ions …             Cellulose Nanofiber Paper as an Ultra Flexible Nonvolatile Memory ▶     Kazuki Nagashima, Hirotaka Koga, Umberto Celano et al.     On the development of flexible electronics, a highly flexible nonvolatile memory, which is an important circuit component for the portability, is necessary. However, the …             Preparing two-dimensional microporous carbon from Pistachio nutshell with high areal capacitance as supercapacitor materials ▶     Jiandong Xu, Qiuming Gao, Yunlu Zhang et al.     Two-dimensional (2D) porous carbon AC-SPN-3 possessing of amazing high micropore volume ratio of 83% and large surface area of about 1069 m2 g−1 is high-yield obtained by …             Encoding a qubit with Majorana modes in superconducting circuits ▶     J. Q. You, Z. D. Wang, Wenxian Zhang et al.     Majorana fermions are long-sought exotic particles that are their own antiparticles. Here we propose to utilize superconducting circuits to construct two superconducting-qubit …             Anisotropic Fabry-Pérot resonant states confined within nano-steps on the topological insulator surface ▶     Zhen-Guo Fu, Ping Zhang, Mu Chen et al.     The peculiar nature of topological surface states, such as absence of backscattering, weak anti-localization, and quantum anomalous Hall effect, has been demonstrated mainly in …             Cooperation with both synergistic and local interactions can be worse than each alone ▶     Aming Li, Bin Wu, Long Wang     Cooperation is ubiquitous ranging from multicellular organisms to human societies. Population structures indicating individuals' limited interaction ranges are crucial to …             A ‘Clicked’ Tetrameric Hydroxamic Acid Glycopeptidomimetic Antagonizes Sugar-Lectin Interactions On The Cellular Level ▶     Hai-Lin Zhang, Yi Zang, Juan Xie et al.     A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent ‘click …             Multi-color broadband visible light source via GaN hexagonal annular structure ▶     Young-Ho Ko, Jie Song, Benjamin Leung et al.     Multi-color and broadband visible emission was realized thorough the hexagonal annular structure of GaN. The annular structure fabricated by selective-area growth emitted purple, …             Graphene-protected copper and silver plasmonics ▶     V. G. Kravets, R. Jalil, Y.-J. Kim et al.     Plasmonics has established itself as a branch of physics which promises to revolutionize data processing, improve photovoltaics, and increase sensitivity of bio-detection. A …             Atomic-Scale Observation of Migration and Coalescence of Au Nanoclusters on YSZ Surface by Aberration-Corrected STEM ▶     Junjie Li, Zhongchang Wang, Chunlin Chen et al.     Unraveling structural dynamics of noble metal nanoclusters on oxide supports is critical to understanding reaction process and origin of catalytic activity in heterogeneous …             Separating Oil-Water Nanoemulsions using Flux-Enhanced Hierarchical Membranes ▶     Brian R. Solomon, Md. Nasim Hyder, Kripa K. Varanasi     Membranes that separate oil-water mixtures based on contrasting wetting properties have recently received significant attention. Separation of nanoemulsions, i.e. oil-water …             Mesoporous TiO2 Bragg Stack Templated by Graft Copolymer for Dye-sensitized Solar Cells ▶     Jung Tae Park, Won Seok Chi, Sang Jin Kim et al.     Organized mesoporous TiO2 Bragg stacks (om-TiO2 BS) consisting of alternating high and low refractive index organized mesoporous TiO2 (om-TiO2) films were prepared to enhance dye …             Scale-estimation of quantum coherent energy transport in multiple-minima systems ▶     Tristan Farrow, Vlatko Vedral     A generic and intuitive model for coherent energy transport in multiple minima systems coupled to a quantum mechanical bath is shown. Using a simple spin-boson system, we …             Tumor regression achieved by encapsulating a moderately soluble drug into a polymeric thermogel ▶     Tianyuan Ci, Liang Chen, Lin Yu et al.     For cancer chemotherapy, a tumor regression without any surgical resection and severe side effects is greatly preferred to merely slowing down the growth of tumors. Here, we …               Earth & Environmental Sciences ▲ top               Charge-to-mass Ratio of Saltating Particles in Wind-Blown Sand ▶     Tian-Li Bo, Huan Zhang, Xiao-Jing Zheng     The electrification of sand particles plays an important role in aeolian events. In this paper, the charge-to-mass ratio vertical profiles of saltating particles in wind-blown …             Environmental variability and biodiversity of megabenthos on the Hebrides Terrace Seamount (Northeast Atlantic) ▶     Lea-Anne Henry, Johanne Vad, Helen S. Findlay et al.     We present the first remotely operated vehicle investigation of megabenthic communities (1004–1695 m water depth) on the Hebrides Terrace Seamount (Northeast Atlantic). …             Ancient harbour infrastructure in the Levant: tracking the birth and rise of new forms of anthropogenic pressure ▶     Nick Marriner, Christophe Morhange, David Kaniewski et al.     Beirut, Sidon and Tyre were major centres of maritime trade from the Bronze Age onwards. This economic prosperity generated increased pressures on the local environment, through …             Warming climate extends dryness-controlled areas of terrestrial carbon sequestration ▶     Chuixiang Yi, Suhua Wei, George Hendrey     At biome-scale, terrestrial carbon uptake is controlled mainly by weather variability. Observational data from a global monitoring network indicate that the sensitivity of …             Soot superaggregates from flaming wildfires and their direct radiative forcing ▶     Rajan K. Chakrabarty, Nicholas D. Beres, Hans Moosmüller et al.     Wildfires contribute significantly to global soot emissions, yet their aerosol formation mechanisms and resulting particle properties are poorly understood and parameterized in …               Health Sciences ▲ top               Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance ▶     Hongbiao Jing, Guoming Zhang, Lingsheng Meng et al.     Gankyrin is an important oncoprotein that is overexpressed in human hepatocellular carcinoma (HCC). However, the gradual alteration of Gankyrin in successive stages during human …             TR-FRET Assays of Huntingtin Protein Fragments Reveal Temperature and PolyQ Length-Dependent Conformational Changes ▶     Xiaotian Cui, Qingnan Liang, Yijian Liang et al.     Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) technology is a widely used immunoassay that enables high-throughput quantitative measurements of proteins of …             TGF-β1, IL-6, and TNF-α in Bronchoalveolar Lavage Fluid: Useful Markers for Lung Cancer? ▶     Zhongbo Chen, Zhiwei Xu, Shifang Sun et al.     Changes of cytokines in bronchoalveolar lavage fluid (BALF) reflect immunologic reactions of the lung in pulmonary malignancies. Detection of biomarkers in BALF might serve as an …             Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1) ▶     Bart J. G. Broeckx, Frank Coopman, Geert E. C. Verhoeven et al.     Whole exome sequencing is a technique that aims to selectively sequence all exons of protein-coding genes. A canine whole exome sequencing enrichment kit was designed based on the …             Computational prediction of microRNA networks incorporating environmental toxicity and disease etiology ▶     Jie Li, Zengrui Wu, Feixiong Cheng et al.     MicroRNAs (miRNAs) play important roles in multiple biological processes and have attracted much scientific attention recently. Their expression can be altered by environmental …             Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's saliva samples using stochastic microsensors ▶     Raluca-Ioana Stefan-van Staden, Livia Alexandra Gugoaşă, Bogdan Calenic et al.     Stochastic microsensors based on diamond paste and three types of electroactive materials (maltodextrin (MD), α-cyclodextrin (α-CD) and 5,10,15,20-tetraphenyl-21H,23H porphyrin …             Increased leukemia-associated gene expression in benzene-exposed workers ▶     Keqiu Li, Yaqing Jing, Caihong Yang et al.     Long-term exposure to benzene causes several adverse health effects, including an increased risk of acute myeloid leukemia. This study was to identify genetic alternations …             An early origin for detailed perception in Autism Spectrum Disorder: biased sensitivity for high-spatial frequency information. ▶     Luc Kéïta, Jacalyn Guy, Claude Berthiaume et al.     Autistics demonstrate superior performances on several visuo-spatial tasks where local or detailed information processing is advantageous. Altered spatial filtering properties at …             Stress and self-efficacy predict psychological adjustment at diagnosis of prostate cancer ▶     Ruth Curtis, AnnMarie Groarke, Frank Sullivan     Prostate cancer is the most frequently non-skin cancer diagnosed among men. Diagnosis, a significant burden, generates many challenges which impact on emotional adjustment and so …             Distinguishing between cancer cell differentiation and resistance induced by all-trans retinoic acid using transcriptional profiles and functional pathway analysis ▶     Song-Mei Liu, Weiping Chen, Jin Wang     All-trans retinoic acid (ATRA) induces differentiation in various cell types and has been investigated extensively for its effective use in cancer prevention and treatment. …             Protective Effect of Dl-3n-butylphthalide on Learning and Memory Impairment Induced by Chronic Intermittent Hypoxia-Hypercapnia Exposure ▶     Jing-jing Min, Xin-long Huo, ling-yun Xiang et al.     Cognitive impairment is a common finding in patients with chronic obstructive pulmonary disease (COPD), but little attention has been focused on therapeutic intervention for this …             Association between the MLX Interacting Protein-Like, BUD13 Homolog and Zinc Finger Protein 259 Gene Polymorphisms and Serum Lipid Levels ▶     Lynn-Htet-Htet Aung, Rui-Xing Yin, Jin-Zhen Wu et al.     This study aimed to detect the association between the MLX interacting protein-like (MLXIPL), BUD13 homolog (BUD13) and zinc finger protein 259 (ZNF259) single nucleotide …             Clinical implication of changes in serum adiponectin in patients with hepatogenic diabetes ▶     Zhongying Bao, Xiaodong Yuan, Shuhong Duan et al.     Adiponectin is a protein hormone that modulates glucose metabolism and fatty acid oxidation. We explored the clinical implication of serum adiponectin in hepatogenic diabetes. …             The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ42 internalization ▶     Bianca Da Costa Dias, Katarina Jovanovic, Danielle Gonsalves et al.     Neuronal loss is a major neuropathological hallmark of Alzheimer's disease (AD). The associations between soluble Aβ oligomers and cellular components cause this neurotoxicity. …             Mice Deficient in Intestinal Epithelium Cytochrome P450 Reductase are Prone to Acute Toxin-induced Mucosal Damage ▶     Sarita Ahlawat, Fang Xie, Yi Zhu et al.     Cytochrome P450 (P450) enzymes are a superfamily of heme-containing enzymes involved in the metabolism of various endogenous compounds, including retinoids, glucocorticoids, and …             EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression ▶     Huihua Zhang, Xiaojia Chen, Jiakang Wang et al.     Early growth response 1 (EGR1) is a multifunctional transcription factor; Positive and negative functions of EGR1 in various tumors rely on the integrated functions of various …             NF-κB-to-AP-1 Switch: A Mechanism Regulating Transition From Endothelial Barrier Injury to Repair in Endotoxemic Mice ▶     Gang Liu, Xiaobing Ye, Edmund J. Miller et al.     Endothelial barrier disruption is a hallmark of multiple organ injury (MOI). However, mechanisms governing the restoration of endothelial barrier function are poorly understood. …             Cytotoxic activity of acyl phloroglucinols isolated from the leaves of Eucalyptus cinerea F. Muell. ex Benth. cultivated in Egypt ▶     Fathy M. Soliman, Magda M. Fathy, Maha M. Salama et al.     Two acyl phloroglucinol compounds namely; Sideroxylonal B (1) and Macrocarpal A (2) were isolated from the Sideroxylonal-Rich Extract (SRE) of the juvenile leaves of Eucalyptus …             Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival ▶     Silke Fuchs, Ermelinda Rende, Andrea Crisanti et al.     Insecticide resistance amongst disease vectors is a growing problem and novel compounds are needed. Biogenic amines are important for neurotransmission and we have recently shown …             PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis ▶     Menghan Liu, Magdalene K. Montgomery, Corrine E. Fiveash et al.     Excess dietary lipid generally leads to fat deposition and impaired glucose homeostasis, but consumption of fish oil (FO) alleviates many of these detrimental effects. The …             Effects of hydrogen-rich water on aging periodontal tissues in rats ▶     Takaaki Tomofuji, Yuya Kawabata, Kenta Kasuyama et al.     Oxidative damage is involved in age-related inflammatory reactions. The anti-oxidative effects of hydrogen-rich water suppress oxidative damage, which may aid in inhibiting …             Dynamics of inflammation resolution and symptom recovery during AECOPD treatment ▶     Chun Chang, Zhiguo Guo, Ning Shen et al.     The association between increases in both systemic and airway inflammation and acute exacerbation of COPD (AECOPD) has been reported by many studies. However, relatively little is …             The association between air pollution and mortality in Thailand ▶     Yuming Guo, Shanshan Li, Benjawan Tawatsupa et al.     Bayesian statistical inference with a case-crossover design was used to examine the effects of air pollutants {Particulate matter <10 μm in aerodynamic diameter (PM10), sulphur …             Eupolyphaga sinensis Walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling ▶     Yanmin Zhang, Yingzhuan Zhan, Dongdong Zhang et al.     Tumor growth and metastasis are responsible for most cancer patients' deaths. Here, we report that eupolyphaga sinensis walker has an essential role in resisting hepatocellular …             Macroscopic Stiffness of Breast Tumors Predicts Metastasis ▶     Joseph Fenner, Amanda C. Stacer, Frank Winterroth et al.     Mechanical properties of tumors differ substantially from normal cells and tissues. Changes in stiffness or elasticity regulate pro-metastatic behaviors of cancer cells, but …             Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF ▶     Yoshiyuki Yamazaki, Yukihiko Hirai, Koichi Miyake et al.     Enzyme replacement via the cerebrospinal fluid (CSF) has been shown to ameliorate neurological symptoms in model animals with neuropathic metabolic disorders. 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