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2014/09/23

Scientific Reports Table of Contents e-alert: 23 September 2014

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Biological Sciences top
 
 
 
 
 
 
 

A sensitive method for the quantification of virion-sense and complementary-sense DNA strands of circular single-stranded DNA viruses

 
 

Edgar A. Rodríguez-Negrete, Sonia Sánchez-Campos, M. Carmen Cañizares et al.

 
 

Circular single-stranded DNA (ssDNA) viruses are the smallest viruses known to infect eukaryotes. High recombination and mutation rates have conferred these viruses with an …

 
 
 
 
 
 

The role of institutional incentives and the exemplar in promoting cooperation

 
 

Jia-Jia Wu, Cong Li, Bo-Yu Zhang et al.

 
 

People on average do not play their individually rational Nash equilibrium (NE) strategy in game experiments based on the public goods game (PGG) that model social dilemmas. …

 
 
 
 
 
 

Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies

 
 

Antonia A. Dominguez, H. Rosaria Chiang, Meena Sukhwani et al.

 
 

Turner syndrome is caused by complete or partial loss of the second sex chromosome and is characterized by spontaneous fetal loss in >90% of conceptions. Survivors possess an …

 
 
 
 
 
 

Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

 
 

Xiaolin Li, Evandro Fei Fang, Morten Scheibye-Knudsen et al.

 
 

Di-(2-ethylhexyl)-phthalate (DEHP) is a ubiquitously used endocrine disruptor.There is widespread exposure to DEHP in the general population which has raised substantial public …

 
 
 
 
 
 

Serum Stable Natural Peptides Designed by mRNA Display

 
 

Shannon M. Howell, Stephen V. Fiacco, Terry T. Takahashi et al.

 
 

Peptides constructed with the 20 natural amino acids are generally considered to have little therapeutic potential because they are unstable in the presence of proteases and …

 
 
 
 
 
 

CORRIGENDUM: CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes

 
 

Yuki Hasegawa, Dave Tang, Naoko Takahashi et al.

 
 

 
 
 
 
 
 

An Efficient Genotyping Method for Genome-modified Animals and Human Cells Generated with CRISPR/Cas9 System

 
 

Xiaoxiao Zhu, Yajie Xu, Shanshan Yu et al.

 
 

The rapid generation of various species and strains of laboratory animals using CRISPR/Cas9 technology has dramatically accelerated the interrogation of gene function in vivo. So …

 
 
 
 
 
 

Towards an in vitro model mimicking the foreign body response: tailoring the surface properties of biomaterials to modulate extracellular matrix

 
 

Febriyani F. R. Damanik, Tonia C. Rothuizen, Clemens van Blitterswijk et al.

 
 

Despite various studies to minimize host reaction following a biomaterial implantation, an appealing strategy in regenerative medicine is to actively use such an immune response …

 
 
 
 
 
 

Mechanosensitive Kinases Regulate Stiffness-Induced Cardiomyocyte Maturation

 
 

Jennifer L. Young, Kyle Kretchmer, Matthew G. Ondeck et al.

 
 

Cells secrete and assemble extracellular matrix throughout development, giving rise to time-dependent, tissue-specific stiffness. Mimicking myocardial matrix stiffening, i.e. …

 
 
 
 
 
 

Multiple interacting brain areas underlie successful spatiotemporal memory retrieval in humans

 
 

Amber M. Schedlbauer, Milagros S. Copara, Andrew J. Watrous et al.

 
 

Emerging evidence suggests that our memories for recent events depend on a dynamic interplay between multiple cortical brain regions, although previous research has also …

 
 
 
 
 
 

Cell-surface receptor control that depends on the size of a synthetic equilateral-triangular RNA-protein complex

 
 

Yoshihiko Fujita, Rie Furushima, Hirohisa Ohno et al.

 
 

A human cell surface displays many complex-structured receptors for receiving extracellular signals to regulate cellular functions. The use of precisely regulated signal-controls …

 
 
 
 
 
 

siRNAs targeted to Smad4 prevent renal fibrosis in vivo

 
 

Yoshiyuki Morishita, Hiromichi Yoshizawa, Minami Watanabe et al.

 
 

Renal fibrosis is the final common pathway leading to decreased renal function. No therapy has been established to prevent it. In order to establish a therapeutic approach and …

 
 
 
 
 
 

Prediction of post-earthquake depressive and anxiety symptoms: a longitudinal resting-state fMRI study

 
 

Jinyi Long, Xiaoqi Huang, Yi Liao et al.

 
 

Neurobiological markers of stress symptom progression for healthy survivors from a disaster (e.g., an earthquake) would greatly help with early intervention to prevent the …

 
 
 
 
 
 

Impact of Recombinant Globular Adiponectin on Early Warm Ischemia-Reperfusion Injury in Rat Bile Duct after Liver Transplantation

 
 

Yang Xia, Jian-Ping Gong

 
 

Adiponectin (APN) is an adipocyte protein with anti-diabetic properties, which has been recently revealed to have anti-inflammatory activity in organ ischemia- reperfusion injury …

 
 
 
 
 
 

Pathogenic Eukaryotes in Gut Microbiota of Western Lowland Gorillas as Revealed by Molecular Survey

 
 

Ibrahim Hamad, Mamadou B. Keita, Martine Peeters et al.

 
 

Although gorillas regarded as the largest extant species of primates and have a close phylogenetic relationship with humans, eukaryotic communities have not been previously …

 
 
 
 
 
 

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

 
 

Ulrike Mock, Kristoffer Riecken, Belinda Berdien et al.

 
 

TAL-effector nucleases (TALENs) are attractive tools for sequence-specific genome modifications, but their delivery still remains problematic. It is well known that the presence …

 
 
 
 
 
 

A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor

 
 

Bi-Feng Chen, Yick-Keung Suen, Shen Gu et al.

 
 

It was previously demonstrated that microRNA-199a (miR-199a) was down-regulated in testicular germ cell tumor (TGCT) partially caused by hypermethylation of its promoter. …

 
 
 
 
 
 

Describing Myxococcus xanthus Aggregation Using Ostwald Ripening Equations for Thin Liquid Films

 
 

Fatmagül Bahar, Philip C. Pratt-Szeliga, Stuart Angus et al.

 
 

When starved, a swarm of millions of Myxococcus xanthus cells coordinate their movement from outward swarming to inward coalescence. The cells then execute a synchronous program …

 
 
 
 
 
 

A broad spectrum of genomic changes in latinamerican patients with EXT1/EXT2-CDG

 
 

M. A. Delgado, G. Martinez-Domenech, P. Sarrión et al.

 
 

Multiple osteochondromatosis (MO), or EXT1/EXT2-CDG, is an autosomal dominant O-linked glycosylation disorder characterized by the formation of multiple cartilage-capped tumors …

 
 
 
 
 
 

Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology

 
 

Hui Yang, Jing-Jing Li, Shuai Liu et al.

 
 

Expansion of polyglutamine (polyQ) tract may cause protein misfolding and aggregation that lead to cytotoxicity and neurodegeneration, but the underlying mechanism remains to be …

 
 
 
 
 
 

A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine

 
 

Kuen-Haur Lee, Hsiang-Ling Lo, Wan-Chun Tang et al.

 
 

Berberine (BBR), a traditional Chinese herbal medicine, was shown to display anticancer activity. In this study, we attempted to provide a global view of the molecular pathways …

 
 
 
 
 
 

On-chip immobilization of planarians for in vivo imaging

 
 

Joseph P. Dexter, Mary B. Tamme, Christine H. Lind et al.

 
 

Planarians are an important model organism for regeneration and stem cell research. A complete understanding of stem cell and regeneration dynamics in these animals requires …

 
 
 
 
 
 

Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration

 
 

Ines M. L. Wolf, Zheng Fan, Manfred Rauh et al.

 
 

Malignant gliomas are characterized by neurodegenerative actions leading to the destruction of surrounding brain parenchyma. The disturbance in glutamate homeostasis caused by …

 
 
 
 
 
 

Micromonospora from nitrogen fixing nodules of alfalfa (Medicago sativa L.). A new promising Plant Probiotic Bacteria.

 
 

Pilar Martínez-Hidalgo, Purificación Galindo-Villardón, José M. Igual et al.

 
 

Biotic interactions can improve agricultural productivity without costly and environmentally challenging inputs. Micromonospora strains have recently been reported as natural …

 
 
 
 
 
 

Rapid comparison and correlation analysis among massive number of microbial community samples based on MDV data model

 
 

Xiaoquan Su, Jianqiang Hu, Shi Huang et al.

 
 

The research in microbial communities would potentially impact a vast number of applications in “bio”-related disciplines. Large-scale analyses became a clear trend in microbial …

 
 
 
 
 
 

Nickel oxide nanoparticles film produced by dead biomass of filamentous fungus

 
 

Marcia Regina Salvadori, Cláudio Augusto Oller Nascimento, Benedito Corrêa

 
 

The synthesis of nickel oxide nanoparticles in film form using dead biomass of the filamentous fungus Aspergillus aculeatus as reducing agent represents an environmentally …

 
 
 
 
 
 

Real Time Ligand-Induced Motion Mappings of AChBP and nAChR Using X-ray Single Molecule Tracking

 
 

Hiroshi Sekiguchi, Yasuhito Suzuki, Yuri Nishino et al.

 
 

We observed the dynamic three-dimensional (3D) single molecule behaviour of acetylcholine-binding protein (AChBP) and nicotinic acetylcholine receptor (nAChR) using a single …

 
 
 
 
 
 

Stem cell senescence. Effects of REAC technology on telomerase-independent and telomerase-dependent pathways

 
 

S. Rinaldi, M. Maioli, G. Pigliaru et al.

 
 

Decline in the gene expression of senescence repressor Bmi1, and telomerase, together with telomere shortening, underlay senescence of stem cells cultured for multiple passages. …

 
 
 
 
 
 

Demographic response of cutlassfish (Trichiurus japonicus and T. nanhaiensis) to fluctuating palaeo-climate and regional oceanographic conditions in the China seas

 
 

Lijun He, Aibing Zhang, David Weese et al.

 
 

Glacial cycles of the Quaternary have heavily influenced the demographic history of various species. To test the evolutionary impact of palaeo-geologic and climatic events on the …

 
 
 
 
 
 
 
 
The Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Nature Genetics, and Nature Reviews Cancer present: NUCLEAR REPROGRAMMING AND THE CANCER GENOME 2014
October 31- November 2, 2014
Ramada Plaza, Guangzhou, China
 
Click here for more information or to register for this conference today! 
 
 
 
 
Chemical Sciences top
 
 
 
 
 
 
 

How to be smart and energy efficient: A general discussion on thermochromic windows

 
 

Linshuang Long, Hong Ye

 
 

A window is a unique element in a building because of its simultaneous properties of being “opaque” to inclement weather yet transparent to the observer. However, these unique …

 
 
 
 
 
 

A Macroscopic Reaction: Direct Covalent Bond Formation between Materials Using a Suzuki-Miyaura Cross-Coupling Reaction

 
 

Tomoko Sekine, Takahiro Kakuta, Takashi Nakamura et al.

 
 

Cross-coupling reactions are important to form C–C covalent bonds using metal catalysts. Although many different cross-coupling reactions have been developed and applied to …

 
 
 
 
 
 

Touching polymer chains by organic field-effect transistors

 
 

Wei Shao, Huanli Dong, Zhigang Wang et al.

 
 

Organic field-effect transistors (OFETs) are used to directly “touch” the movement and dynamics of polymer chains, and then determine Tg. As a molecular-level probe, the …

 
 
 
 
 
 
 
 
Nature Insight Exoplanets
Almost 20 years after the discovery of the first exoplanet this Insight brings together a selection of reviews discussing our current theoretical understanding of exoplanets and their atmospheres, the missions that led to exoplanet discovery and the instruments, both present and future, that characterize planetary atmospheres.

Access the Insight online.

 
 
 
 
Physical Sciences top
 
 
 
 
 
 
 

Plasma nitriding induced growth of Pt-nanowire arrays as high performance electrocatalysts for fuel cells

 
 

Shangfeng Du, Kaijie Lin, Sairam K. Malladi et al.

 
 

In this work, we demonstrate an innovative approach, combing a novel active screen plasma (ASP) technique with green chemical synthesis, for a direct fabrication of uniform Pt …

 
 
 
 
 
 

Surface plasmon coupling dynamics in InGaN/GaN quantum-well structures and radiative efficiency improvement

 
 

Ahmed Fadil, Daisuke Iida, Yuntian Chen et al.

 
 

Surface plasmonics from metal nanoparticles have been demonstrated as an effective way of improving the performance of low-efficiency light emitters. However, reducing the …

 
 
 
 
 
 

Impurities as a quantum thermometer for a Bose-Einstein condensate

 
 

Carlos Sabín, Angela White, Lucia Hackermuller et al.

 
 

We introduce a primary thermometer which measures the temperature of a Bose-Einstein Condensate in the sub-nK regime. We show, using quantum Fisher information, that the …

 
 
 
 
 
 

Filling schemes at submicron scale: Development of submicron sized plasmonic colour filters

 
 

Ranjith Rajasekharan, Eugeniu Balaur, Alexander Minovich et al.

 
 

The pixel size imposes a fundamental limit on the amount of information that can be displayed or recorded on a sensor. Thus, there is strong motivation to reduce the pixel size …

 
 
 
 
 
 

Novel structural phases and superconductivity of iridium telluride under high pressures

 
 

Bin Li, Guiqin Huang, Jian Sun et al.

 
 

Transition metal selenide and telluride have recently receive considerable attention due to their possible structural relation to ferropnictide. Pressure is often used as an …

 
 
 
 
 
 

Low on-resistance diamond field effect transistor with high-k ZrO2 as dielectric

 
 

Jiangwei Liu, Meiyong Liao, Masataka Imura et al.

 
 

Although several high-k insulators have been deposited on the diamond for metal-insulator-semiconductor field effect transistors (MISFETs) fabrication, the k values and current …

 
 
 
 
 
 

Direct generation of 2-ps blue pulses from gain-switched InGaN VCSEL assessed by up-conversion technique

 
 

Akifumi Asahara, Shaoqiang Chen, Takashi Ito et al.

 
 

Ultra-short pulses in blue region generated from compact and low-cost semiconductor lasers have attracted much attention for a wide variety of applications. Nitride-based …

 
 
 
 
 
 

Double Charge Ordering States and Spin Ordering State Observed in a RFe2O4 System

 
 

Fei Sun, Rui Wang, C. Aku-Leh et al.

 
 

Charge, spin, and lattice degrees of orderings are of great interest in the layered quantum material RFe2O4 (R=Y, Er, Yb, Tm, and Lu) system. Recently many unique properties …

 
 
 
 
 
 

Dynamically fluctuating electric dipole moments in fullerene-based magnets

 
 

Takashi Kambe, Kokichi Oshima

 
 

We report here the direct evidence of the existence of a permanent electric dipole moment in both crystal phases of a fullerene-based magnet—the ferromagnetic α-phase and the …

 
 
 
 
 
 

How to be smart and energy efficient: A general discussion on thermochromic windows

 
 

Linshuang Long, Hong Ye

 
 

A window is a unique element in a building because of its simultaneous properties of being “opaque” to inclement weather yet transparent to the observer. However, these unique …

 
 
 
 
 
 

Spontaneous emission noise in long-range surface plasmon polariton waveguide based optical gyroscope

 
 

Yang-Yang Wang, Tong Zhang

 
 

Spontaneous emission noise is an important limit to the performance of active plasmonic devices. Here, we investigate the spontaneous emission noise in the long-range surface …

 
 
 
 
 
 

Additional modes in a waveguide system of zero-index-metamaterials with defects

 
 

Yangyang Fu, Yadong Xu, Huanyang Chen

 
 

Zero-index-metamaterials (ZIM) have drawn much attention due to their intriguing properties and novel applications. Particularly, in a parallel plated ZIM waveguide system with …

 
 
 
 
 
 

High performance organic transistor active-matrix driver developed on paper substrate

 
 

Boyu Peng, Xiaochen Ren, Zongrong Wang et al.

 
 

The fabrication of electronic circuits on unconventional substrates largely broadens their application areas. For example, green electronics achieved through utilization of …

 
 
 
 
 
 

Towards an in vitro model mimicking the foreign body response: tailoring the surface properties of biomaterials to modulate extracellular matrix

 
 

Febriyani F. R. Damanik, Tonia C. Rothuizen, Clemens van Blitterswijk et al.

 
 

Despite various studies to minimize host reaction following a biomaterial implantation, an appealing strategy in regenerative medicine is to actively use such an immune response …

 
 
 
 
 
 

A Macroscopic Reaction: Direct Covalent Bond Formation between Materials Using a Suzuki-Miyaura Cross-Coupling Reaction

 
 

Tomoko Sekine, Takahiro Kakuta, Takashi Nakamura et al.

 
 

Cross-coupling reactions are important to form C–C covalent bonds using metal catalysts. Although many different cross-coupling reactions have been developed and applied to …

 
 
 
 
 
 

Competitive growth mechanisms of AlN on Si (111) by MOVPE

 
 

Yuxia Feng, Hongyuan Wei, Shaoyan Yang et al.

 
 

To improve the growth rate and crystal quality of AlN, the competitive growth mechanisms of AlN under different parameters were studied. The mass transport limited mechanism was …

 
 
 
 
 
 

Extreme tunability in aluminum doped Zinc Oxide plasmonic materials for near-infrared applications

 
 

A. K. Pradhan, R. M. Mundle, Kevin Santiago et al.

 
 

Plasmonic materials (PMs), featuring large static or dynamic tunability, have significant impact on the optical properties due to their potential for applications in …

 
 
 
 
 
 

Symmetry restoration and quantumness reestablishment

 
 

Guo-Mo Zeng, Lian-Ao Wu, Hai-Jun Xing

 
 

A realistic quantum many-body system, characterized by a generic microscopic Hamiltonian, is accessible only through approximation methods. The mean field theories, as the …

 
 
 
 
 
 

Independent control of differently-polarized waves using anisotropic gradient-index metamaterials

 
 

Hui Feng Ma, Gui Zhen Wang, Wei Xiang Jiang et al.

 
 

We propose a kind of anisotropic gradient-index (GRIN) metamaterials, which can be used to control differently-polarized waves independently. We show that two three- dimensional …

 
 
 
 
 
 

Alloy Cu3Pt nanoframes through the structure evolution in Cu-Pt nanoparticles with a core-shell construction

 
 

Lin Han, Hui Liu, Penglei Cui et al.

 
 

Noble metal nanoparticles with hollow interiors and customizable shell compositions have immense potential for catalysis. Herein, we present an unique structure transformation …

 
 
 
 
 
 

Interfacing whispering-gallery microresonators and free space light with cavity enhanced Rayleigh scattering

 
 

Jiangang Zhu, Åžahin K. Özdemir, Huzeyfe Yilmaz et al.

 
 

Whispering gallery mode resonators (WGMRs) take advantage of strong light confinement and long photon lifetime for applications in sensing, optomechanics, microlasers and quantum …

 
 
 
 
 
 

Computational Study of In-Plane Phonon Transport in Si Thin Films

 
 

Xinjiang Wang, Baoling Huang

 
 

We have systematically investigated the in-plane thermal transport in Si thin films using an approach based on the first-principles calculations and lattice dynamics. The effects …

 
 
 
 
 
 

Negative Optical Torque

 
 

Jun Chen, Jack Ng, Kun Ding et al.

 
 

Light carries angular momentum, and as such it can exert torques on material objects. Applications of these opto-mechanical effects were limited initially due to their smallness …

 
 
 
 
 
 

Flat Focusing Mirror

 
 

Y. C. Cheng, S. Kicas, J. Trull et al.

 
 

The control of spatial propagation properties of narrow light beams such as divergence, focusing or imaging are main objectives in optics and photonics. In this letter, we …

 
 
 
 
 
 

Cerium; Crystal Structure and Position in The Periodic Table

 
 

Börje Johansson, Wei Luo, Sa Li et al.

 
 

The properties of the cerium metal have intrigued physicists and chemists for many decades. In particular a lot of attention has been directed towards its high pressure behavior, …

 
 
 
 
 
 

Touching polymer chains by organic field-effect transistors

 
 

Wei Shao, Huanli Dong, Zhigang Wang et al.

 
 

Organic field-effect transistors (OFETs) are used to directly “touch” the movement and dynamics of polymer chains, and then determine Tg. As a molecular-level probe, the …

 
 
 
 
 
 

Nickel oxide nanoparticles film produced by dead biomass of filamentous fungus

 
 

Marcia Regina Salvadori, Cláudio Augusto Oller Nascimento, Benedito Corrêa

 
 

The synthesis of nickel oxide nanoparticles in film form using dead biomass of the filamentous fungus Aspergillus aculeatus as reducing agent represents an environmentally …

 
 
 
 
 
 

Optofluidic lens with tunable focal length and asphericity

 
 

Kartikeya Mishra, Chandrashekhar Murade, Bruno Carreel et al.

 
 

Adaptive micro-lenses enable the design of very compact optical systems with tunable imaging properties. Conventional adaptive micro-lenses suffer from substantial spherical …

 
 
 
 
 
 

Strain-controlled thermal conductivity in ferroic twinned films

 
 

Suzhi Li, Xiangdong Ding, Jie Ren et al.

 
 

Large reversible changes of thermal conductivity are induced by mechanical stress, and the corresponding device is a key element for phononics applications. We show that the …

 
 
 
 
 
 

Imperfect chimera states for coupled pendula

 
 

Tomasz Kapitaniak, Patrycja Kuzma, Jerzy Wojewoda et al.

 
 

The phenomenon of chimera states in the systems of coupled, identical oscillators has attracted a great deal of recent theoretical and experimental interest. In such a state, …

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

Origin of cold bias over the Arabian Sea in Climate Models

 
 

S. Sandeep, R. S. Ajayamohan

 
 

Almost all climate models in Coupled Model Inter-comparison Project phase five (CMIP5) were found to have a cold bias in Sea Surface Temperature (SST) over the northern Arabian …

 
 
 
 
 
 

Nickel oxide nanoparticles film produced by dead biomass of filamentous fungus

 
 

Marcia Regina Salvadori, Cláudio Augusto Oller Nascimento, Benedito Corrêa

 
 

The synthesis of nickel oxide nanoparticles in film form using dead biomass of the filamentous fungus Aspergillus aculeatus as reducing agent represents an environmentally …

 
 
 
 
 
 

Demographic response of cutlassfish (Trichiurus japonicus and T. nanhaiensis) to fluctuating palaeo-climate and regional oceanographic conditions in the China seas

 
 

Lijun He, Aibing Zhang, David Weese et al.

 
 

Glacial cycles of the Quaternary have heavily influenced the demographic history of various species. To test the evolutionary impact of palaeo-geologic and climatic events on the …

 
 
 
 
 
 

Cyclic precipitation variation on the western Loess Plateau of China during the past four centuries

 
 

Liangcheng Tan, Zhisheng An, Chih-An Huh et al.

 
 

Precipitation variation on the Loess Plateau (LP) of China is not only important for rain-fed agriculture in this environmentally sensitive region, but also critical for the …

 
 
 
 
 
 
 
Health Sciences top
 
 
 
 
 
 
 

Serological evidence of H7, H5 and H9 avian influenza virus co-infection among herons in a city park in Jiangxi, China

 
 

Guirong Wang, Tao Zhang, Xiaowen Li et al.

 
 

Extensive surveillance of influenza A viruses in different avian species is critical for understanding its transmission. Here, a breeding colony of Little Egrets and …

 
 
 
 
 
 

A sensitive method for the quantification of virion-sense and complementary-sense DNA strands of circular single-stranded DNA viruses

 
 

Edgar A. Rodríguez-Negrete, Sonia Sánchez-Campos, M. Carmen Cañizares et al.

 
 

Circular single-stranded DNA (ssDNA) viruses are the smallest viruses known to infect eukaryotes. High recombination and mutation rates have conferred these viruses with an …

 
 
 
 
 
 

Impact of Recombinant Globular Adiponectin on Early Warm Ischemia-Reperfusion Injury in Rat Bile Duct after Liver Transplantation

 
 

Yang Xia, Jian-Ping Gong

 
 

Adiponectin (APN) is an adipocyte protein with anti-diabetic properties, which has been recently revealed to have anti-inflammatory activity in organ ischemia- reperfusion injury …

 
 
 
 
 
 

Pubertal Onset in Girls is Strongly Influenced by Genetic Variation Affecting FSH Action

 
 

Casper P. Hagen, Kaspar Sørensen, Lise Aksglaede et al.

 
 

Age at pubertal onset varies substantially in healthy girls. Although genetic factors are responsible for more than half of the phenotypic variation, only a small part has been …

 
 
 
 
 
 

Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis

 
 

Junichi Hirahashi, Kimito Kawahata, Makoto Arita et al.

 
 

Small-vessel vasculitis is a life-threatening autoimmune disease that is frequently associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Conventional immunotherapy …

 
 
 
 
 
 

Electrophysiological, behavioral and histological characterization of paclitaxel, cisplatin, vincristine and bortezomib-induced neuropathy in C57Bl/6 mice

 
 

Wolfgang Boehmerle, Petra Huehnchen, Sarah Peruzzaro et al.

 
 

Polyneuropathy is a frequent and potentially severe side effect of clinical tumor chemotherapy. The goal of this study was to characterize paclitaxel-, cisplatin-, vincristine- …

 
 
 
 
 
 

Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

 
 

Kristina Rydell-Törmänen, Kristofer Andréasson, Roger Hesselstrand et al.

 
 

The ECM exerts great effects on cells, and changed composition may therefore have profound impact. Small leucine-rich proteoglycans, e.g. fibromodulin, are essential in collagen …

 
 
 
 
 
 

Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology

 
 

Hui Yang, Jing-Jing Li, Shuai Liu et al.

 
 

Expansion of polyglutamine (polyQ) tract may cause protein misfolding and aggregation that lead to cytotoxicity and neurodegeneration, but the underlying mechanism remains to be …

 
 
 
 
 
 

The Effort-reward Imbalance work-stress model and daytime salivary cortisol and dehydroepiandrosterone (DHEA) among Japanese women

 
 

Atsuhiko Ota, Junji Mase, Nopporn Howteerakul et al.

 
 

We examined the influence of work-related effort–reward imbalance and overcommitment to work (OC), as derived from Siegrist's Effort–Reward Imbalance (ERI) model, on the …

 
 
 
 
 
 

Looking beyond endotoxin: a comparative study of pyrogen retention by ultrafilters used for the preparation of sterile dialyis fluid

 
 

Griet Glorieux, Michael Hulko, Rose Speidel et al.

 
 

Sterile single-use ultrafilters are used in dialysis for the preparation of the substitution fluid given to patients undergoing dialysis treatments with high convective fluid …

 
 
 
 
 
 
 
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