Immunology and Cell Biology - Table of Contents alert Volume 93 Issue 4

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The April 2015 issue contains a Special Feature on “Chemokines in cellular positioning and human disease”. Chemokines serve as critical extracellular mediators of cell migration and retention. Recent studies have highlighted the importance of how cells are positioned within peripheral and lymphoid tissues for the development of timely effector and memory responses. In addition, advances in structural determination of chemokine receptor-ligand complexes and the identification of genetic mutations that impact cell migration have brought us closer to targeting this system for the development of new anti-inflammatory and anti-tumor based drugs. Immunology and Cell Biology thanks the coordinator of this Special Feature - Joanna Groom - for her planning and input. TABLE OF CONTENTS Volume 93, Issue 4 (April 2015) In this issue News And Commentaries Editorial Reviews Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe News And Commentaries Top Boosting regulatory T-cell function with the humanized CD4-specific humanized monoclonal antibody Tregalizumab (BT-061) Stéphanie Humblet-Baron and Frédéric Baron Immunol Cell Biol 2015 93: 321-322; advance online publication, February 10, 2015; 10.1038/icb.2014.120 Full Text Multiple checkpoints on the long road towards cancer immunotherapy Tri Giang Phan, Georgina V Long and Richard A Scolyer Immunol Cell Biol 2015 93: 323-325; advance online publication, February 17, 2015; 10.1038/icb.2015.12 Full Text Prolonged access to thymic epithelial MHCI seals CD8+ lineage commitment Stephen R Daley Immunol Cell Biol 2015 93: 326-327; advance online publication, March 10, 2015; 10.1038/icb.2015.28 Full Text Editorial Top Chemokines in cellular positioning and human disease Joanna R Groom Immunol Cell Biol 2015 93: 328-329; 10.1038/icb.2015.27 Full Text | PDF Reviews Top Moving to the suburbs: T-cell positioning within lymph nodes during activation and memory Joanna R Groom Immunol Cell Biol 2015 93: 330-336; advance online publication, March 10, 2015; 10.1038/icb.2015.29 Abstract | Full Text The role of chemokines in cutaneous immunosurveillance Sioh-Yang Tan, Ben Roediger and Wolfgang Weninger Immunol Cell Biol 2015 93: 337-346; advance online publication, March 17, 2015; 10.1038/icb.2015.16 Abstract | Full Text Chemokine-mediated immune responses in the female genital tract mucosa Maud Deruaz and Andrew D Luster Immunol Cell Biol 2015 93: 347-354; advance online publication, March 17, 2015; 10.1038/icb.2015.20 Abstract | Full Text Controlling the fire — tissue-specific mechanisms of effector regulatory T-cell homing Zachary Chow, Ashish Banerjee and Michael J Hickey Immunol Cell Biol 2015 93: 355-363; advance online publication, January 13, 2015; 10.1038/icb.2014.117 Abstract | Full Text Chemokines, their receptors and human disease: the good, the bad and the itchy Vanessa L Bryant and Charlotte A Slade Immunol Cell Biol 2015 93: 364-371; 10.1038/icb.2015.23 Abstract | Full Text Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies Irina Kufareva, Catherina L Salanga and Tracy M Handel Immunol Cell Biol 2015 93: 372-383; advance online publication, February 24, 2015; 10.1038/icb.2015.15 Abstract | Full Text Original Articles Top The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model Ondřej Ballek, Jan Valečka, Jasper Manning and Dominik Filipp Immunol Cell Biol 2015 93: 384-395; advance online publication, November 25, 2014; 10.1038/icb.2014.100 Abstract | Full Text A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway OPEN Bianca Helling, Martin König, Benjamin Dälken, Andre Engling, Wolfgang Krömer, Katharina Heim, Holger Wallmeier, Jürgen Haas, Brigitte Wildemann, Brigitte Fritz, Helmut Jonuleit, Jan Kubach, Theodor Dingermann, Heinfried H Radeke, Frank Osterroth, Christoph Uherek, Niklas Czeloth and Jörg Schüttrumpf Immunol Cell Biol 2015 93: 396-405; advance online publication, December 16, 2014; 10.1038/icb.2014.102 Abstract | Full Text A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes Charles Sinclair, Masahiro Ono and Benedict Seddon Immunol Cell Biol 2015 93: 406-416; advance online publication, January 20, 2015; 10.1038/icb.2014.107 Abstract | Full Text Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3+ and Foxp3− T cells OPEN Dean Franckaert, James Dooley, Evelyne Roos, Stefan Floess, Jochen Huehn, Herve Luche, Hans Joerg Fehling, Adrian Liston, Michelle A Linterman and Susan M Schlenner Immunol Cell Biol 2015 93: 417-423; advance online publication, December 23, 2014; 10.1038/icb.2014.108 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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