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TABLE OF CONTENTS |
October 2015 Volume 33, Issue 10 |
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| Editorials News Bioentrepreneur Opinion and Comment Features News and Views Computational Biology Research Careers and Recruitment
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Nature Microbiology: Call for Papers
Launching in January 2016, Nature Microbiology is now open for submissions and inviting high-quality submissions. The journal will cover all aspects of microorganisms be it their evolution, physiology and cell biology, their interactions with each other, with a host, with an environment, or their societal significance.
Submit your next research paper to the journal. | | | |
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Editorials | Top |
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Standing up for science p1009 doi:10.1038/nbt.3384 Smear campaigns against those speaking out against scaremongering on genetically modified (GM) crops highlight why support for scientists involved in public outreach is so important.
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No sample left behind p1010 doi:10.1038/nbt.3381 Maximizing the clinical impact of immune profiling will require dedicated immune monitoring facilities and community standards for handling patient samples.
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News | Top |
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Ebola vaccine trial falls short of homerun pp1011 - 1012 Laura DeFrancesco doi:10.1038/nbt1015-1011
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Roche gobbles Smarticles p1012 doi:10.1038/nbt1015-1012a
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Illumina opens Helix genomics store p1012 doi:10.1038/nbt1015-1012b
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First US biosimilar launch p1013 doi:10.1038/nbt1015-1013b
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GSK collaborates with Apple on ResearchKit pp1013 - 1014 Michael Eisenstein doi:10.1038/nbt1015-1013a
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First 3D-printed pill p1014 doi:10.1038/nbt1015-1014a
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Syngenta rebuffs Monsanto, again p1014 doi:10.1038/nbt1015-1014b
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Cat poop coffee goes biotech p1014 doi:10.1038/nbt1015-1014c
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Landmark green light for Mosquirix malaria vaccine pp1015 - 1016 Chris Morrison doi:10.1038/nbt1015-1015
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Around the world in a month p1016 doi:10.1038/nbt1015-1016
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Kirk, to boldly go into synthetic biology pp1017 - 1018 Emily Waltz doi:10.1038/nbt1015-1017
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News Feature |
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Gene drive overdrive pp1019 - 1021 doi:10.1038/nbt.3361 The recent publication of a simple procedure for creating a CRISPR-Cas9-mediated gene drive has some researchers sounding the alarm. What are the risks to populations in the wild and what precautions are necessary? Laura DeFrancesco investigates.
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Enhanced MALDI-TOF MS Performance and Flexibility From a linear-only system to a unique QIT-TOF configuration to a high-resolution, high-energy TOF-TOF, Shimadzu's suite of MALDI mass spectrometers easily meets the needs of researchers with varying applications and budgets. Mine your data using our comprehensive software solutions. Learn more. | | |
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Bioentrepreneur | Top |
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Building a business |
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Philanthropy's role in translating scientific innovation pp1022 - 1025 Hemai Parthasarathy and Lindy Fishburne doi:10.1038/nbt.3369
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Opinion and Comment | Top |
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Correspondence |
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Lessons in simplicity that should shape the future of drug delivery pp1026 - 1027 Koen Raemdonck and Stefaan C De Smedt doi:10.1038/nbt.3366
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Professionalism and ethics in animal research pp1027 - 1028 Nikola Biller-Andorno, Herwig Grimm and Rebecca L Walker doi:10.1038/nbt.3363
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Chinese government reaffirms backing for GM products p1029 Rongrong Li, Qiang Wang and Alan McHughen doi:10.1038/nbt.3362
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Increased bioavailable vitamin B6 in field-grown transgenic cassava for dietary sufficiency pp1029 - 1032 Kuan-Te Li, Michael Moulin, Nathalie Mangel, Monique Albersen, Nanda M Verhoeven-Duif et al. doi:10.1038/nbt.3318
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Features | Top |
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Patents |
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Gene patent practice across plant and human genomes pp1033 - 1038 Osmat A Jefferson, Deniz Kollhofer, Thomas H Ehrich and Richard A Jefferson doi:10.1038/nbt.3364 The uses of genetic sequences to inform, enable or create products or services for human biomedicine are substantially different from their uses in crop-based agriculture.
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Recent patents in synthetic nucleic acids and proteins p1039 doi:10.1038/nbt.3382
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News and Views | Top |
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Computational Biology | Top |
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Analysis |
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ConStrains identifies microbial strains in metagenomic datasets pp1045 - 1052 Chengwei Luo, Rob Knight, Heli Siljander, Mikael Knip, Ramnik J Xavier et al. doi:10.1038/nbt.3319 Different bacterial strains in a metagenome are distinguished using a method that detects SNPs in conserved genes.
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Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning pp1053 - 1060 Brian Cleary, Ilana Lauren Brito, Katherine Huang, Dirk Gevers, Terrance Shea et al. doi:10.1038/nbt.3329 Bacterial strains that make up as little as 0.00001% of a microbial community are detected in metagenomic sequencing data.
See also: News and Views by Brown
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Research | Top |
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Perspective |
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Systems strategies for developing industrial microbial strains pp1061 - 1072 Sang Yup Lee and Hyun Uk Kim doi:10.1038/nbt.3365
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Brief Communications |
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Subangstrom single-molecule measurements of motor proteins using a nanopore pp1073 - 1075 Ian M Derrington, Jonathan M Craig, Eric Stava, Andrew H Laszlo, Brian C Ross et al. doi:10.1038/nbt.3357 The movement of single motor proteins on DNA is measured at subangstrom resolution using a nanopore.
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Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering pp1076 - 1078 Dieter Blancquaert, Jeroen Van Daele, Simon Strobbe, Filip Kiekens, Sergei Storozhenko et al. doi:10.1038/nbt.3358 Folate stability in stored biofortified rice is improved by complexing to folate-binding proteins.
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Article |
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Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1 pp1079 - 1086 Tao Dao, Dmitry Pankov, Andrew Scott, Tatyana Korontsvit, Victoriya Zakhaleva et al. doi:10.1038/nbt.3349 A bi-specific antibody that binds both T cells and a tumor-specific intracellular antigen shows therapeutic promise in mouse models of cancer.
See also: News and Views by Salter & Riddell
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Letters |
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De novo sequencing and variant calling with nanopores using PoreSeq pp1087 - 1091 Tamas Szalay and Jene A Golovchenko doi:10.1038/nbt.3360 Nanopore sequencing of microbial genomes is achieved at low coverage without a reference genome using PoreSeq.
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Optogenetic control of endogenous Ca2+ channels in vivo pp1092 - 1096 Taeyoon Kyung, Sangkyu Lee, Jung Eun Kim, Taesup Cho, Hyerim Park et al. doi:10.1038/nbt.3350 A single-component optogenetic tool controls calcium fluxes with high dynamic range.
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Engineering pulmonary vasculature in decellularized rat and human lungs pp1097 - 1102 Xi Ren, Philipp T Moser, Sarah E Gilpin, Tatsuya Okamoto, Tong Wu et al. doi:10.1038/nbt.3354 In a step toward bioengineered lungs, the vasculature is regenerated in decellularized rat and human lung scaffolds.
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Resources |
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A catalog of the mouse gut metagenome pp1103 - 1108 Liang Xiao, Qiang Feng, Suisha Liang, Si Brask Sonne, Zhongkui Xia et al. doi:10.1038/nbt.3353 The mouse gut microbiome is catalogued and compared to the human microbiome.
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Errata |
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Erratum: Prediction of human population responses to toxic compounds by a collaborative competition p1109 Federica Eduati, Lara M Mangravite, Tao Wang, Hao Tang, J Christopher Bare et al. doi:10.1038/nbt1015-1109a
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Erratum: Drug pipeline: 2Q15 p1109 Laura DeFrancesco doi:10.1038/nbt1015-1109b
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Corrigendum |
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Corrigendum: Assembling large genomes with single-molecule sequencing and locality-sensitive hashing p1109 Konstantin Berlin, Sergey Koren, Chen-Shan Chin, James P Drake, Jane M Landolin et al. doi:10.1038/nbt1015-1109c
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Careers and Recruitment | Top |
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The right track for you in biotech and biomedical sciences pp1110 - 1111 Laxmi Ravi Iyer and Sandhya Sriram doi:10.1038/nbt.3376 In Singapore, a recent panel showcased the many career paths and options available for those in the biotech sector.
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People |
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People p1112 doi:10.1038/nbt.3379
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Nature Plants: Call for Papers
Nature Plants launched in January and covers all aspects of plants be it their evolution, genetics, development or metabolism, their interactions with the environment, or their societal significance. The journal welcomes high quality submissions and encourages you and your colleagues to consider submitting your next research paper to the journal.
Submit your next research paper to the journal. | | | |
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| | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com | | | | | |
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