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October 2016 Volume 17 Number 10 | Advertisement | ||||||||||||||||||||||||||||||||||||||||||||||
In this issue Comment Research Highlights Reviews Correspondence
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Article series: Scaling up neuroscience Comment: The rise of team neuroscience James L. Olds p601 | doi:10.1038/nrn.2016.116 James Olds argues that gaining a true understanding of brain structure and function will require neuroscientists to adopt a team-based approach to research and considers some of the challenges that this presents for the field. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
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REVIEWS | Top | ||||||||||||||||||||||||||||||||||||||||||||||
The cellular mechanisms that maintain neuronal polarity Marvin Bentley & Gary Banker p611 | doi:10.1038/nrn.2016.100 Axons and dendrites contain distinct complements of membrane proteins, consistent with their different roles in electrochemical signalling. In this Review, Bentley and Banker discuss the intracellular machinery that ensures that axonal and dendritic proteins are accurately targeted to the correct domains. Abstract | Full Text | PDF | Supplementary information | |||||||||||||||||||||||||||||||||||||||||||||||
Emerging roles of GluN3-containing NMDA receptors in the CNS Isabel Pérez-Otaño, Rylan S. Larsen & John F. Wesseling p623 | doi:10.1038/nrn.2016.92 NMDA receptors that contain GluN3 subunits have several non-conventional properties that set them apart from 'classical' NMDA receptors. Pérez-Otaño and colleagues describe the important roles of these receptors in CNS development and their potential involvement in CNS disease. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
Region-specific roles of the corticotropin-releasing factor-urocortin system in stress Marloes J. A. G. Henckens, Jan M. Deussing & Alon Chen p636 | doi:10.1038/nrn.2016.94 Corticotropin-releasing factor (CRF) and urocortins have traditionally been proposed to promote stress and stress recovery, respectively. However, recent findings suggest that this view is overly simplistic. Chen and colleagues review evidence showing that CRF-receptor signalling is region- and cell type-specific and influenced by the individual's experience. Abstract | Full Text | PDF | Supplementary information | |||||||||||||||||||||||||||||||||||||||||||||||
The effects of childhood maltreatment on brain structure, function and connectivity Martin H. Teicher, Jacqueline A. Samson, Carl M. Anderson & Kyoko Ohashi p652 | doi:10.1038/nrn.2016.111 Adverse childhood experiences have a wide range of effects on the structure, function and connectivity of the developing brain. Teicher et al. suggest that such changes might reflect adaptive modifications that, in some susceptible individuals, could contribute to psychopathology. Abstract | Full Text | PDF | Supplementary information | |||||||||||||||||||||||||||||||||||||||||||||||
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Future directions for identifying the neural correlates of consciousness Kristian Sandberg, Stefan Frässle & Michael Pitts p666 | doi:10.1038/nrn.2016.104 Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
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Posterior and anterior cortex — where is the difference that makes the difference? Christof Koch, Marcello Massimini, Melanie Boly & Giulio Tononi p666 | doi:10.1038/nrn.2016.105 Full Text | PDF | |||||||||||||||||||||||||||||||||||||||||||||||
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