Nature Genetics Contents: Volume 54 Number 7

In this Issue: Editorial Comment News & Views Research Highlights Research Briefings Perspectives Articles Amendments & Corrections

Nature Genetics Contents: Volume 54 Issue 7

Editorial

Mendel, memories and meaning Editorial | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01146-4

Comment

30 years of progress from positional cloning to precision genome editing Kevin Davies Comment | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01128-6

Democratizing plant genomics to accelerate global food production Carol Nkechi Ibe Comment | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01122-y

News & Views

Deciphering the regulatory logic of a chromatin domain boundary A. Marieke Oudelaar News & Views | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01086-z

Automated sequence-based annotation and interpretation of the human genome Anshul Kundaje & Wouter Meuleman News & Views | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01123-x

Decoding the zebrafish genome Nathan D. Lawson News & Views | 04 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01080-5

Graph pangenomes find missing heritability David Edwards & Jacqueline Batley News & Views | 23 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01099-8

Research Highlights

Lineage tracing in lung cancer Safia Danovi Research Highlight | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01135-7

Mapping genetic variants to cellular contexts Michael Fletcher Research Highlight | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01136-6

Potato genome diversity Wei Li Research Highlight | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01137-5

FTO regulates LINE1 in early development Tiago Faial Research Highlight | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01138-4

Keeping the beat Kyle Vogan Research Highlight | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01139-3

Research Briefings

Linking genetic variants to kidney disease via the epigenome Research Briefing | 23 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01098-9

Identification of two intrinsic epithelial subtypes of colorectal cancer Research Briefing | 07 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01101-3

Perspectives

How did Mendel arrive at his discoveries? Peter J. van Dijk, Adrienne P. Jessop & T. H. Noel Ellis Perspective | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01109-9

From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill Brian Charlesworth, Michael E. Goddard, Karin Meyer, Peter M. Visscher, Bruce S. Weir et al. Perspective | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01103-1

Articles

A sequence-based global map of regulatory activity for deciphering human genetics Kathleen M. Chen, Aaron K. Wong, Olga G. Troyanskaya & Jian Zhou Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01102-2

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease Hongbo Liu, Tomohito Doke, Dong Guo, Xin Sheng, Ziyuan Ma et al. Article | 16 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01097-w

Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer Ignasius Joanito, Pratyaksha Wirapati, Nancy Zhao, Zahid Nawaz, Grace Yeo et al. Article | 30 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01100-4

A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells Mariangela Russo, Simone Pompei, Alberto Sogari, Mattia Corigliano, Giovanni Crisafulli et al. Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01105-z

Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer Winston R. Becker, Stephanie A. Nevins, Derek C. Chen, Roxanne Chiu, Aaron M. Horning et al. Article | 20 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01088-x

Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity Xiaoxiao Ma, Nadeem Riaz, Robert M. Samstein, Mark Lee, Vladimir Makarov et al. Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01108-w

DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution Shanshan Zhang, Dylan Plummer, Leina Lu, Jian Cui, Wanying Xu et al. Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01116-w

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation Chiara Anania, Rafael D. Acemel, Johanna Jedamzick, Adriano Bolondi, Giulia Cova et al. Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01117-9

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements Damir Baranasic, Matthias Hörtenhuber, Piotr J. Balwierz, Tobias Zehnder, Abdul Kadir Mukarram et al. Article | 04 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01089-w

Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development Lijiang Fei, Haide Chen, Lifeng Ma, Weigao E, Renying Wang et al. Article | 11 July 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01118-8

Amendments & Corrections

Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease Douglas P. Wightman, Iris E. Jansen, Jeanne E. Savage, Alexey A. Shadrin, Shahram Bahrami et al. Author Correction | 20 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01126-8

Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs Malgorzata Gozdecka, Eshwar Meduri, Milena Mazan, Konstantinos Tzelepis, Monika Dudek et al. Publisher Correction | 14 June 2022 Nature Genetics 54 | doi:10.1038/s41588-022-01060-9

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