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2012/11/13

Scientific Reports Table of Contents e-alert: 13 November 2012

  13 November 2012   
 
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Biological Sciences top
 
 
 
 
 
 
 

Hapten Mediated Display and Pairing of Recombinant Antibodies Accelerates Assay Assembly for Biothreat Countermeasures

 
 

Laura J. Sherwood, Andrew Hayhurst

 
 

A bottle-neck in recombinant antibody sandwich immunoassay development is pairing, demanding protein purification and modification to distinguish captor from tracer. We developed …

 
 
 
 
 
 

Virus-induced gene complementation reveals a transcription factor network in modulation of tomato fruit ripening

 
 

Tao Zhou, Hang Zhang, Tongfei Lai et al.

 
 

Plant virus technology, in particular virus-induced gene silencing, is a widely used reverse- and forward-genetics tool in plant functional genomics. However the potential of …

 
 
 
 
 
 

You mob my owl, I’ll mob yours: birds play tit-for-tat game

 
 

Tatjana Krama, Jolanta Vrublevska, Todd M. Freeberg et al.

 
 

Reciprocity is fundamental to cooperative behaviour and has been verified in theoretical models. However, there is still limited experimental evidence for reciprocity in …

 
 
 
 
 
 

Quantitative, spectrally-resolved intraoperative fluorescence imaging

 
 

Pablo A. Valdés, Frederic Leblond, Valerie L. Jacobs et al.

 
 

Intraoperative visual fluorescence imaging (vFI) has emerged as a promising aid to surgical guidance, but does not fully exploit the potential of the fluorescent agents that are …

 
 
 
 
 
 

Assignment and secondary structure of the YadA membrane protein by solid-state MAS NMR

 
 

Shakeel A. Shahid, Stefan Markovic, Dirk Linke et al.

 
 

We report the complete solid-state MAS NMR resonance assignment of a medium-sized, trimeric membrane protein, YadA-M. The protein YadA (Yersinia adhesin A) is an important …

 
 
 
 
 
 

BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice

 
 

H. Fukui, H. T. Wong, L. A. Beyer et al.

 
 

Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a procedure that …

 
 
 
 
 
 

Biomaterial evolution parallels behavioral innovation in the origin of orb-like spider webs

 
 

Todd A. Blackledge, Matjaž Kuntner, Mohammad Marhabaie et al.

 
 

Correlated evolution of traits can act synergistically to facilitate organism function. But, what happens when constraints exist on the evolvability of some traits, but not …

 
 
 
 
 
 

Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

 
 

Noritaka Kawasaki, Rie Asada, Atsushi Saito et al.

 
 

Adipose tissue plays a central role in maintaining metabolic homeostasis under normal conditions. Metabolic diseases such as obesity and type 2 diabetes are often accompanied by …

 
 
 
 
 
 

RETRACTION: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals

 
 

Hisashi Moriguchi, Yue Zhang, Makoto Mihara et al.

 
 

 
 
 
 
 
 

RETRACTION: Successful cryopreservation of human ovarian cortex tissues using supercooling

 
 

Hisashi Moriguchi, Yue Zhang, Makoto Mihara et al.

 
 

 
 
 
 
 
 

Characterization of coagulation factor synthesis in nine human primary cell types

 
 

Monireh Dashty, Vishtaseb Akbarkhanzadeh, Clark J. Zeebregts et al.

 
 

The coagulation/fibrinolysis system is essential for wound healing after vascular injury. According to the standard paradigm, the synthesis of most coagulation factors is …

 
 
 
 
 
 

A Novel Tumor suppressor network in squamous malignancies

 
 

Clotilde Costa, Mirentxu Santos, Carmen Segrelles et al.

 
 

The specific ablation of Rb1 gene in stratified epithelia (RbF/F;K14cre) promotes proliferation and altered differentiation but is insufficient to produce spontaneous tumors. The …

 
 
 
 
 
 

Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

 
 

Hiroshi Ueki, Tomona Mizushina, Titaree Laoharatchatathanin et al.

 
 

Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether …

 
 
 
 
 
 

Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1

 
 

Raquel Bienes-Martínez, Angel Ordóñez, Mónica Feijoo-Cuaresma et al.

 
 

Thrombospondin-1 is a matricellular protein with potent antitumour activities, the levels of which determine the fate of many different tumours, including renal carcinomas. …

 
 
 
 
 
 

Sequential detection of temporal communities by estrangement confinement

 
 

Vikas Kawadia, Sameet Sreenivasan

 
 

Temporal communities are the result of a consistent partitioning of nodes across multiple snapshots of an evolving network, and they provide insights into how dense clusters in a …

 
 
 
 
 
 

Nano-visualization of oriented-immobilized IgGs on immunosensors by high-speed atomic force microscopy

 
 

Masumi Iijima, Masaharu Somiya, Nobuo Yoshimoto et al.

 
 

Oriented immobilization of sensing molecules on solid phases is an important issue in biosensing. In case of immunosensors, it is essential to scrutinize not only the direction …

 
 
 
 
 
 

Multimodal imaging of human cerebellum - merging X-ray phase microtomography, magnetic resonance microscopy and histology

 
 

Georg Schulz, Conny Waschkies, Franz Pfeiffer et al.

 
 

Imaging modalities including magnetic resonance imaging and X-ray computed tomography are established methods in daily clinical diagnosis of human brain. Clinical equipment does …

 
 
 
 
 
 

Modulating DNA Translocation by a Controlled Deformation of a PDMS Nanochannel Device

 
 

Paola Fanzio, Chiara Manneschi, Elena Angeli et al.

 
 

Several strategies have been developed for the control of DNA translocation in nanopores and nanochannels. However, the possibility to reduce the molecule speed is still …

 
 
 
 
 
 

ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo

 
 

Carlos Barcia, Carmen María Ros, Valentina Annese et al.

 
 

The role of microglial motility in the context of adult neurodegeneration is poorly understood. In the present work, we investigated the microanatomical details of …

 
 
 
 
 
 

Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy

 
 

Chin-Chih Lin, Tsung-Lin Cheng, Wen-Hui Tsai et al.

 
 

To investigate whether altered energy metabolism induces the Warburg effect and results in tumor malignancy, the respiratory enzyme citrate synthase (CS) was examined, silenced, …

 
 
 
 
 
 

A chemical genomic study identifying diversity in cell migration signaling in cancer cells

 
 

Shigeyuki Magi, Etsu Tashiro, Masaya Imoto

 
 

The aim of this study was to analyze the diversity and consistency of regulatory signaling in cancer cell migration, using a chemical genomic approach. The effects of 34 small …

 
 
 
 
 
 

RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence

 
 

Mei-Ling Kuo, Alexander J. Sy, Lijun Xue et al.

 
 

RRM2B is the DNA damage-inducible small subunit of ribonucleotide reductase, the rate-limiting enzyme in de novo deoxyribonucleoside triphosphate synthesis. Although RRM2B is …

 
 
 
 
 
 

Characterisation of the organophosphate hydrolase catalytic activity of SsoPox

 
 

Julien Hiblot, Guillaume Gotthard, Eric Chabriere et al.

 
 

SsoPox is a lactonase endowed with promiscuous phosphotriesterase activity isolated from Sulfolobus solfataricus that belongs to the Phosphotriesterase-Like Lactonase family. …

 
 
 
 
 
 

Targeted transcript profiling by sequencing

 
 

Pawel Zajac, Afshin Ahmadian

 
 

In this work we present a targeted gene expression strategy employing trinucleotide threading (TnT) amplification and massive parallel sequencing. We have previously shown that …

 
 
 
 
 
 

Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes

 
 

Mingyong Liu, Keqiang Chen, Teizo Yoshimura et al.

 
 

Listeria monocytogenes (Listeria) causes opportunistic infection in immunocompromised hosts with high mortality. Resistance to Listeria depends on immune responses and recruitment …

 
 
 
 
 
 

A functioning artificial secretory cell

 
 

Lisa Simonsson, Michael E. Kurczy, Raphaël Trouillon et al.

 
 

We present an amperometric study of content release from individual vesicles in an artificial secretory cell designed with the minimal components required to carry out exocytosis. …

 
 
 
 
 
 

Fluorescence laser microdissection reveals a distinct pattern of gene activation in the mouse hippocampal region

 
 

Wataru Yoshioka, Nozomi Endo, Akie Kurashige et al.

 
 

A histoanatomical context is imperative in an analysis of gene expression in a cell in a tissue to elucidate physiological function of the cell. In this study, we made technical …

 
 
 
 
 
 
 
 
Chemical Sciences top
 
 
 
 
 
 
 

Asymmetric light propagation in composition-graded semiconductor nanowires

 
 

Jinyou Xu, Xiujuan Zhuang, Pengfei Guo et al.

 
 

Asymmetric light propagation is crucial to the development of optical-based functional components in nanophotonics. Diverse configurations and structures have been proposed to …

 
 
 
 
 
 

Surface-plasmon-enhanced deep-UV light emitting diodes based on AlGaN multi-quantum wells

 
 

Na Gao, Kai Huang, Jinchai Li et al.

 
 

We report the development of complete structural AlGaN-based deep-ultraviolet light-emitting diodes with an aluminum thin layer for increasing light extraction efficiency. A 217% …

 
 
 
 
 
 

Size effects in Atomic-Level Epitaxial Redistribution Process of RuO2 over TiO2

 
 

Guolei Xiang, Xuejun Shi, Yulong Wu et al.

 
 

Controls over the atomic dispersity and particle shape of noble metal catalysts are the major qualities determining their usability in industrial runs, but they are usually …

 
 
 
 
 
 

Floating nematic phase in colloidal platelet-sphere mixtures

 
 

Daniel de las Heras, Nisha Doshi, Terence Cosgrove et al.

 
 

The phase behaviour of colloidal dispersions is interesting for fundamental reasons and for technological applications such as photonic crystals and electronic paper. …

 
 
 
 
 
 

A functioning artificial secretory cell

 
 

Lisa Simonsson, Michael E. Kurczy, Raphaël Trouillon et al.

 
 

We present an amperometric study of content release from individual vesicles in an artificial secretory cell designed with the minimal components required to carry out exocytosis. …

 
 
 
 
 
 

A real-time dynamic holographic material using a fast photochromic molecule

 
 

Norihito Ishii, Tetsuya Kato, Jiro Abe

 
 

We have developed a real-time, dynamic holographic material that exhibits rapid colouration upon irradiation with UV light and successive fast thermal bleaching within tens of …

 
 
 
 
 
 

Inexpensive method for producing macroporous silicon particulates (MPSPs) with pyrolyzed polyacrylonitrile for lithium ion batteries

 
 

Madhuri Thakur, Steven L. Sinsabaugh, Mark J. Isaacson et al.

 
 

One of the most exciting areas in lithium ion batteries is engineering structured silicon anodes. These new materials promise to lead the next generation of batteries with …

 
 
 
 
 
 

Radiation-Suppressed plasmonic open resonators designed by nonmagnetic transformation optics

 
 

Hongyi Xu, Xingjue Wang, Tianyuan Yu et al.

 
 

How to confine light energy associated with surface plasmon polaritons (SPPs) in a physical space with minimal radiation loss whereas creating maximum interacting section with …

 
 
 
 
 
 
 
 
Physical Sciences top
 
 
 
 
 
 
 

A monolithically integrated polarization entangled photon pair source on a silicon chip

 
 

Nobuyuki Matsuda, Hanna Le Jeannic, Hiroshi Fukuda et al.

 
 

Integrated photonic circuits are one of the most promising platforms for large-scale photonic quantum information systems due to their small physical size and stable …

 
 
 
 
 
 

Leidenfrost levitation: beyond droplets

 
 

Ali Hashmi, Yuhao Xu, Benjamin Coder et al.

 
 

Friction is a major inhibitor in almost every mechanical system. Enlightened by the Leidenfrost effect – a droplet can be levitated by its own vapor layer on a sufficiently hot …

 
 
 
 
 
 

Asymmetric light propagation in composition-graded semiconductor nanowires

 
 

Jinyou Xu, Xiujuan Zhuang, Pengfei Guo et al.

 
 

Asymmetric light propagation is crucial to the development of optical-based functional components in nanophotonics. Diverse configurations and structures have been proposed to …

 
 
 
 
 
 

Vortex Domain Structure in Ferroelectric Nanoplatelets and Control of its Transformation by Mechanical Load

 
 

W. J. Chen, Yue Zheng, Biao Wang

 
 

Vortex domain patterns in low-dimensional ferroelectrics and multiferroics have been extensively studied with the aim of developing nanoscale functional devices. However, control …

 
 
 
 
 
 

Surface-plasmon-enhanced deep-UV light emitting diodes based on AlGaN multi-quantum wells

 
 

Na Gao, Kai Huang, Jinchai Li et al.

 
 

We report the development of complete structural AlGaN-based deep-ultraviolet light-emitting diodes with an aluminum thin layer for increasing light extraction efficiency. A 217% …

 
 
 
 
 
 

Time-Gated Orthogonal Scanning Automated Microscopy (OSAM) for High-speed Cell Detection and Analysis

 
 

Yiqing Lu, Peng Xi, James A. Piper et al.

 
 

We report a new development of orthogonal scanning automated microscopy (OSAM) incorporating time-gated detection to locate rare-event organisms regardless of autofluorescent …

 
 
 
 
 
 

Optical trapping, driving, and arrangement of particles using a tapered fibre probe

 
 

Hongbao Xin, Rui Xu, Baojun Li

 
 

The ability of manipulating mesoscopic objects with high precision and flexibility is extremely important for a wide variety of fields from physics, biochemistry, to biomedicine. …

 
 
 
 
 
 

Comparing the performance of FA, DFA and DMA using different synthetic long-range correlated time series

 
 

Ying-Hui Shao, Gao-Feng Gu, Zhi-Qiang Jiang et al.

 
 

Notwithstanding the significant efforts to develop estimators of long-range correlations (LRC) and to compare their performance, no clear consensus exists on what is the best …

 
 
 
 
 
 

Biomaterial evolution parallels behavioral innovation in the origin of orb-like spider webs

 
 

Todd A. Blackledge, Matjaž Kuntner, Mohammad Marhabaie et al.

 
 

Correlated evolution of traits can act synergistically to facilitate organism function. But, what happens when constraints exist on the evolvability of some traits, but not …

 
 
 
 
 
 

Quantitative, spectrally-resolved intraoperative fluorescence imaging

 
 

Pablo A. Valdés, Frederic Leblond, Valerie L. Jacobs et al.

 
 

Intraoperative visual fluorescence imaging (vFI) has emerged as a promising aid to surgical guidance, but does not fully exploit the potential of the fluorescent agents that are …

 
 
 
 
 
 

Size effects in Atomic-Level Epitaxial Redistribution Process of RuO2 over TiO2

 
 

Guolei Xiang, Xuejun Shi, Yulong Wu et al.

 
 

Controls over the atomic dispersity and particle shape of noble metal catalysts are the major qualities determining their usability in industrial runs, but they are usually …

 
 
 
 
 
 

Floating nematic phase in colloidal platelet-sphere mixtures

 
 

Daniel de las Heras, Nisha Doshi, Terence Cosgrove et al.

 
 

The phase behaviour of colloidal dispersions is interesting for fundamental reasons and for technological applications such as photonic crystals and electronic paper. …

 
 
 
 
 
 

Exchange coupling driven omnidirectional rotatable anisotropy in ferrite doped CoFe thin film

 
 

Guozhi Chai, Nguyen N. Phuoc, C. K. Ong

 
 

Isotropic magnetic materials with high resonant frequencies are useful for applications in microwave devices. Undoped CoFe thin films, as common soft magnetic materials with high …

 
 
 
 
 
 

Modulating DNA Translocation by a Controlled Deformation of a PDMS Nanochannel Device

 
 

Paola Fanzio, Chiara Manneschi, Elena Angeli et al.

 
 

Several strategies have been developed for the control of DNA translocation in nanopores and nanochannels. However, the possibility to reduce the molecule speed is still …

 
 
 
 
 
 

The Origin of Fluorescence from Graphene Oxide

 
 

Jingzhi Shang, Lin Ma, Jiewei Li et al.

 
 

Time-resolved fluorescence measurements of graphene oxide in water show multiexponential decay kinetics ranging from 1 ps to 2 ns. Electron-hole recombination from the bottom of …

 
 
 
 
 
 

Sequential detection of temporal communities by estrangement confinement

 
 

Vikas Kawadia, Sameet Sreenivasan

 
 

Temporal communities are the result of a consistent partitioning of nodes across multiple snapshots of an evolving network, and they provide insights into how dense clusters in a …

 
 
 
 
 
 

Nano-visualization of oriented-immobilized IgGs on immunosensors by high-speed atomic force microscopy

 
 

Masumi Iijima, Masaharu Somiya, Nobuo Yoshimoto et al.

 
 

Oriented immobilization of sensing molecules on solid phases is an important issue in biosensing. In case of immunosensors, it is essential to scrutinize not only the direction …

 
 
 
 
 
 

Multimodal imaging of human cerebellum - merging X-ray phase microtomography, magnetic resonance microscopy and histology

 
 

Georg Schulz, Conny Waschkies, Franz Pfeiffer et al.

 
 

Imaging modalities including magnetic resonance imaging and X-ray computed tomography are established methods in daily clinical diagnosis of human brain. Clinical equipment does …

 
 
 
 
 
 

High temperatures-related elderly mortality varied greatly from year to year: important information for heat-warning systems

 
 

Yuming Guo, Adrian G. Barnett, Shilu Tong

 
 

We examined the variation in association between high temperatures and elderly mortality (age ≥ 75 years) from year to year in 83 US cities between 1987 and 2000. We used a Poisson …

 
 
 
 
 
 

In science “there is no bad publicity”: Papers criticized in comments have high scientific impact

 
 

Filippo Radicchi

 
 

Comments are special types of publications whose aim is to correct or criticize previously published papers. For this reason, comments are believed to make commented papers less …

 
 
 
 
 
 

Modular networks of word correlations on Twitter

 
 

Joachim Mathiesen, Pernille Yde, Mogens H. Jensen

 
 

Complex networks are important tools for analyzing the information flow in many aspects of nature and human society. Using data from the microblogging service Twitter, we study …

 
 
 
 
 
 

There is More than a Power Law in Zipf

 
 

Matthieu Cristelli, Michael Batty, Luciano Pietronero

 
 

The largest cities, the most frequently used words, the income of the richest countries, and the most wealthy billionaires, can be all described in terms of Zipf’s Law, a …

 
 
 
 
 
 

Inexpensive method for producing macroporous silicon particulates (MPSPs) with pyrolyzed polyacrylonitrile for lithium ion batteries

 
 

Madhuri Thakur, Steven L. Sinsabaugh, Mark J. Isaacson et al.

 
 

One of the most exciting areas in lithium ion batteries is engineering structured silicon anodes. These new materials promise to lead the next generation of batteries with …

 
 
 
 
 
 

A functioning artificial secretory cell

 
 

Lisa Simonsson, Michael E. Kurczy, Raphaël Trouillon et al.

 
 

We present an amperometric study of content release from individual vesicles in an artificial secretory cell designed with the minimal components required to carry out exocytosis. …

 
 
 
 
 
 

A real-time dynamic holographic material using a fast photochromic molecule

 
 

Norihito Ishii, Tetsuya Kato, Jiro Abe

 
 

We have developed a real-time, dynamic holographic material that exhibits rapid colouration upon irradiation with UV light and successive fast thermal bleaching within tens of …

 
 
 
 
 
 

Radiation-Suppressed plasmonic open resonators designed by nonmagnetic transformation optics

 
 

Hongyi Xu, Xingjue Wang, Tianyuan Yu et al.

 
 

How to confine light energy associated with surface plasmon polaritons (SPPs) in a physical space with minimal radiation loss whereas creating maximum interacting section with …

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

High temperatures-related elderly mortality varied greatly from year to year: important information for heat-warning systems

 
 

Yuming Guo, Adrian G. Barnett, Shilu Tong

 
 

We examined the variation in association between high temperatures and elderly mortality (age ≥ 75 years) from year to year in 83 US cities between 1987 and 2000. We used a Poisson …

 
 
 
 
 
 

Inexpensive method for producing macroporous silicon particulates (MPSPs) with pyrolyzed polyacrylonitrile for lithium ion batteries

 
 

Madhuri Thakur, Steven L. Sinsabaugh, Mark J. Isaacson et al.

 
 

One of the most exciting areas in lithium ion batteries is engineering structured silicon anodes. These new materials promise to lead the next generation of batteries with …

 
 
 
 
 
 
 
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