TABLE OF CONTENTS
|  |  |  | Volume 20, Issue 12 (December 2012) |  | In this issue Editorial In This Issue Research Highlights Commentary Original Articles Erratum Corrigendum
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Submit your next research to Scientific Reports *mean time for papers published in September 2012 | |  | | | Editorial | Top |  | European Union Support of Gene Therapy Research: A Success StoryDavid Gancberg, Charles Kessler, Arnd Hoeveler and Ruxandra Draghia-Akli Mol Ther 2012 20: 2191-2193; 10.1038/mt.2012.242 Full Text |  | In This Issue | Top |  | In This IssueMol Ther 2012 20: 2194; 10.1038/mt.2012.238 Full Text |  | Research Highlights | Top |  | Research HighlightsMol Ther 2012 20: 2195; 10.1038/mt.2012.239 Full Text |  | Commentary | Top |  | Adenovirus Immunity: X Marks the SpotMasataka Suzuki and Cliona M Rooney Mol Ther 2012 20: 2197-2198; 10.1038/mt.2012.240 Full Text |  |  |  | Still Seeking an Effective “One–Two” Malaria Vaccine PunchJoseph D Smith and Brandon K Sack Mol Ther 2012 20: 2198-2200; 10.1038/mt.2012.241 Full Text |  | Original Articles | Top |  | Pharmacological Enhancement of α-Glucosidase by the Allosteric Chaperone N-acetylcysteineCaterina Porto, Maria C Ferrara, Massimiliano Meli, Emma Acampora, Valeria Avolio, Margherita Rosa, Beatrice Cobucci-Ponzano, Giorgio Colombo, Marco Moracci, Generoso Andria and Giancarlo Parenti Mol Ther 2012 20: 2201-2211; advance online publication, September 18, 2012; 10.1038/mt.2012.152 Abstract | Full Text |  |  |  | AAV9-mediated VEGF-B Gene Transfer Improves Systolic Function in Progressive Left Ventricular HypertrophyJenni Huusko, Line Lottonen, Mari Merentie, Erika Gurzeler, Andrey Anisimov, Atsushi Miyanohara, Kari Alitalo, Pasi Tavi and Seppo Ylä-Herttuala Mol Ther 2012 20: 2212-2221; advance online publication, October 23, 2012; 10.1038/mt.2012.145 Abstract | Full Text |  |  |  | A Tumor-stroma Targeted Oncolytic Adenovirus Replicated in Human Ovary Cancer Samples and Inhibited Growth of Disseminated Solid Tumors in MiceM Veronica Lopez, Angel A Rivera, Diego L Viale, Lorena Benedetti, Nicasio Cuneo, Kristopher J Kimball, Minghui Wang, Joanne T Douglas, Zeng B Zhu, Alicia I Bravo, Manuel Gidekel, Ronald D Alvarez, David T Curiel and Osvaldo L Podhajcer Mol Ther 2012 20: 2222-2233; advance online publication, September 4, 2012; 10.1038/mt.2012.147 Abstract | Full Text |  |  |  | Inflammation, Apoptosis, and Necrosis Induced by Neoadjuvant Fas Ligand Gene Therapy Improves Survival of Dogs With Spontaneous Bone CancerJaime F Modiano, Donald Bellgrau, Gary R Cutter, Susan E Lana, Nicole P Ehrhart, EJ Ehrhart, Vicki L Wilke, J Brad Charles, Sibyl Munson, Milcah C Scott, John Pozniak, Cathy S Carlson, Jerome Schaack and Richard C Duke Mol Ther 2012 20: 2234-2243; advance online publication, July 31, 2012; 10.1038/mt.2012.149 Abstract | Full Text |  |  |  | Targeting TCTP as a New Therapeutic Strategy in Castration-resistant Prostate CancerVirginie Baylot, Maria Katsogiannou, Claudia Andrieu, David Taieb, Julie Acunzo, Sophie Giusiano, Ladan Fazli, Martin Gleave, Carmen Garrido and Palma Rocchi Mol Ther 2012 20: 2244-2256; advance online publication, August 14, 2012; 10.1038/mt.2012.155 Abstract | Full Text |  |  |  | A TLR and Non-TLR Mediated Innate Response to Lentiviruses Restricts Hepatocyte Entry and Can be Ameliorated by Pharmacological BlockadeJudith Agudo, Albert Ruzo, Kipyegon Kitur, Ravi Sachidanandam, J Magarian Blander and Brian D Brown Mol Ther 2012 20: 2257-2267; advance online publication, August 7, 2012; 10.1038/mt.2012.150 Abstract | Full Text |  |  |  | Ad5:Ad48 Hexon Hypervariable Region Substitutions Lead to Toxicity and Increased Inflammatory Responses Following Intravenous DeliveryLynda Coughlan, Angela C Bradshaw, Alan L Parker, Hollie Robinson, Katie White, Jerome Custers, Jaap Goudsmit, Nico Van Roijen, Dan H Barouch, Stuart A Nicklin and Andrew H Baker Mol Ther 2012 20: 2268-2281; advance online publication, August 28, 2012; 10.1038/mt.2012.162 Abstract | Full Text |  |  |  | Buffering Capacity and Size of siRNA Polyplexes Influence Cytokine LevelsQixin Leng, Szu-Ting Chou, Puthupparampil V Scaria, Martin C Woodle and A James Mixson Mol Ther 2012 20: 2282-2290; advance online publication, October 2, 2012; 10.1038/mt.2012.206 Abstract | Full Text |  |  |  | Targeting Axl With an High-affinity Inhibitory AptamerLaura Cerchia, Carla L Esposito, Simona Camorani, Anna Rienzo, Loredana Stasio, Luigi Insabato, Andrea Affuso and Vittorio de Franciscis Mol Ther 2012 20: 2291-2303; advance online publication, August 21, 2012; 10.1038/mt.2012.163 Abstract | Full Text |  |  |  | Robust Suppression of HIV Replication by Intracellularly Expressed Reverse Transcriptase Aptamers Is Independent of Ribozyme ProcessingMargaret J Lange, Tarun K Sharma, Angela S Whatley, Linda A Landon, Michael A Tempesta, Marc C Johnson and Donald H Burke Mol Ther 2012 20: 2304-2314; advance online publication, September 4, 2012; 10.1038/mt.2012.158 Abstract | Full Text |  |  |  | Nonviral Delivery of Small Interfering RNA Into Pancreas-associated Immune Cells Prevents Autoimmune DiabetesWilhem Leconet, Pierre Petit, Sylvie Peraldi-Roux and Damien Bresson Mol Ther 2012 20: 2315-2325; advance online publication, September 18, 2012; 10.1038/mt.2012.190 Abstract | Full Text |  |  |  | Targeted Expression of miR-34a Using the T-VISA System Suppresses Breast Cancer Cell Growth and InvasionLaisheng Li, Xinhua Xie, Jinmei Luo, Min Liu, Shaoyan Xi, Jiaoli Guo, Yanan Kong, Minqing Wu, Jie Gao, Zeming Xie, Jun Tang, Xi Wang, Weidong Wei, Mingtian Yang, Mien-Chie Hung and Xiaoming Xie Mol Ther 2012 20: 2326-2334; advance online publication, October 2, 2012; 10.1038/mt.2012.201 Abstract | Full Text |  |  |  | CD166pos Subpopulation From Differentiated Human ES and iPS Cells Support Repair of Acute Lung InjuryBoon Seng Soh, Dahai Zheng, Julie Su Li Yeo, Henry He Yang, Shi Yan Ng, Lan Hiong Wong, Wencai Zhang, Pin Li, Massimo Nichane, Atasha Asmat, Poo Sing Wong, Peng Cheang Wong, Lin Lin Su, Sakis A Mantalaris, Jia Lu, Wa Xian, Frank McKeon, Jianzhu Chen, Elaine Hsuen Lim and Bing Lim Mol Ther 2012 20: 2335-2346; advance online publication, September 11, 2012; 10.1038/mt.2012.182 Abstract | Full Text |  |  |  | Mesenchymal Stromal Cells Treatment Attenuates Dry Eye in Patients With Chronic Graft-versus-host DiseaseJianyu Weng, Chang He, Peilong Lai, Chenwei Luo, Rong Guo, Suijing Wu, Suxia Geng, Andy Xiangpeng, Xialin Liu and Xin Du Mol Ther 2012 20: 2347-2354; advance online publication, October 16, 2012; 10.1038/mt.2012.208 Abstract | Full Text |  |  |  | ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in HumansSusanne H Sheehy, Christopher JA Duncan, Sean C Elias, Prateek Choudhary, Sumi Biswas, Fenella D Halstead, Katharine A Collins, Nick J Edwards, Alexander D Douglas, Nicholas A Anagnostou, Katie J Ewer, Tom Havelock, Tabitha Mahungu, Carly M Bliss, Kazutoyo Miura, Ian D Poulton, Patrick J Lillie, Richard D Antrobus, Eleanor Berrie, Sarah Moyle, Katherine Gantlett, Stefano Colloca, Riccardo Cortese, Carole A Long, Robert E Sinden, Sarah C Gilbert, Alison M Lawrie, Tom Doherty, Saul N Faust, Alfredo Nicosia, Adrian VS Hill and Simon J Draper Mol Ther 2012 20: 2355-2368; advance online publication, October 23, 2012; 10.1038/mt.2012.223 Abstract | Full Text |  | Erratum | Top |  | Human Erythropoietin Gene Delivery Using an Arginine-grafted Bioreducible Polymer SystemMol Ther 2012 20: 2369; 10.1038/mt.2012.253 Full Text |  | Corrigendum | Top |  | A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing HeartMol Ther 2011 20: 2370; 10.1038/mt.2012.254 Full Text |  |  |  | Molecular Therapy-Nucleic Acids Online.Open Access.High-Quality Research. 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