Nature Reviews Cardiology - Table of Contents alert Volume 10 Issue 1

TABLE OF CONTENTS
January 2013 Volume 10 Number 1
Impact Factor 8.833 *	In this issue Research Highlights News and Views Reviews Also this month  Featured article: Vascular access and closure in coronary angiography and percutaneous intervention Robert A. Byrne, Salvatore Cassese, Maryam Linhardt & Adnan Kastrati
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RESEARCH HIGHLIGHTS Top Lipids: Antibodies against PCSK9—a new era of therapy Published online: 20 November 2012 p1 | doi:10.1038/nrcardio.2012.166 PDF Antiplatelet therapy: ARCTIC leaves platelet testing out in the cold Published online: 20 November 2012 p2 | doi:10.1038/nrcardio.2012.165 PDF Heart failure: Drugs outperform ultrafiltration in acute cardiorenal syndrome Published online: 20 November 2012 p2 | doi:10.1038/nrcardio.2012.173 PDF Heart failure: Promising data for serelaxin Published online: 20 November 2012 p3 | doi:10.1038/nrcardio.2012.174 PDF Atrial fibrillation: First-line catheter ablation therapy—too much too soon? Published online: 13 November 2012 p4 | doi:10.1038/nrcardio.2012.163 PDF Venous thromboembolism: Aspirin ASPIREs to reduce vascular events after VTE Published online: 20 November 2012 p4 | doi:10.1038/nrcardio.2012.168 PDF Diabetes: Dual RAAS blocker trial stopped prematurely Published online: 20 November 2012 p5 | doi:10.1038/nrcardio.2012.169 PDF Lipids: Dalcetrapib raises HDL-cholesterol level, but does not reduce cardiac risk Published online: 20 November 2012 p5 | doi:10.1038/nrcardio.2012.171 PDF Atrial fibrillation: New data on fish oil supplements Published online: 20 November 2012 p5 | doi:10.1038/nrcardio.2012.172 PDF Surgery: Mitral valve repair with CABG surgery Published online: 27 November 2012 p6 | doi:10.1038/nrcardio.2012.176 PDF Lipids: No need to fast before blood tests Published online: 04 December 2012 p6 | doi:10.1038/nrcardio.2012.179 PDF Cardiac resuscitation: Increased survival for patients after in-hospital cardiac arrest Published online: 04 December 2012 p6 | doi:10.1038/nrcardio.2012.180 PDF Prevention: Multivitamins do not reduce the risk of cardiovascular disease Published online: 20 November 2012 p7 | doi:10.1038/nrcardio.2012.175 PDF Arrhythmias: Refined programming accentuates the benefits of ICDs Published online: 27 November 2012 p7 | doi:10.1038/nrcardio.2012.177 PDF Coronary artery disease: FREEDOM trial results published Published online: 20 November 2012 p8 | doi:10.1038/nrcardio.2012.167 PDF Stem cells: Could it be TIME to abandon BMCs? Published online: 20 November 2012 p8 | doi:10.1038/nrcardio.2012.170 PDF Cardiology JOBS of the week PhD on the interface between metabolic states and gene regulation in heart disease The John Curtin School of Medical Research, The Australian National University Post-doctoral Fellow to Study Dystrophic Cardiomyopathy Medical College of Wiscnsin Postdoctoral Fellow Loyola University Chicago, Health Science Campus Postdoc Research Associate Washington University in St Louis (School of Medicine) MRes / PhD Studentships in Cardiovascular, respiratory and neurological sciences research University of Birmingham – College of Medical & Dental Sciences More Science jobs from Cardiology EVENT 3rd International Conference on Clinical & Experimental Cardiology 15.-17.04.13 LA, US More science events from
NEWS AND VIEWS		Top
Heart failure: Optimal postdischarge management of chronic HF Simonetta Scalvini & Amerigo Giordano Published online: 20 November 2012 p9 | doi:10.1038/nrcardio.2012.161 Not all strategies for the management of chronic heart failure have been shown to be equally effective in improving outcomes, and the ideal programme has yet to be defined. The WHICH? trial sheds some light on whether a clinical, in-hospital or a home-based strategy of care is superior and cost-effective. Full Text | PDF
Coronary artery disease: Are β-blockers truly helpful in patients with CAD? Nicolas Danchin & Stéphane Laurent Published online: 13 November 2012 p11 | doi:10.1038/nrcardio.2012.159 In a large, new, observational study, β-blocker treatment did not improve clinical outcomes in patients with coronary artery disease (CAD), including those with previous myocardial infarction, and was associated with more events in individuals with risk factors only. The role of β-blockers for secondary prevention in these patients should be reconsidered. Full Text | PDF
Biomarkers: Screening for C-reactive protein in CVD prediction Sanne A. E. Peters, Frank L. J. Visseren & Diederick E. Grobbee Published online: 20 November 2012 p12 | doi:10.1038/nrcardio.2012.164 Adding C-reactive protein (CRP) level to conventional cardiovascular risk models has been suggested to improve risk prediction for cardiovascular events. However, evaluation of the potential impact of CRP measurement in cardiovascular risk management will require studies designed to quantify the effect of additional CRP assessment on medical decision-making, patient outcomes, and cost-effectiveness. Full Text | PDF
REVIEWS		Top
Myofibroblast-mediated mechanisms of pathological remodelling of the heart Karl T. Weber, Yao Sun, Syamal K. Bhattacharya, Robert A. Ahokas & Ivan C. Gerling Published online: 04 December 2012 p15 | doi:10.1038/nrcardio.2012.158 In the diseased heart, cardiomyocytes undergo necrotic cell death. A healing response results in myofibroblast production of collagen and other matrix molecules, which initially serve to preserve the structural integrity of the myocardium. However, myofibroblast dispersion fails to occur in many cardiac diseases, and perpetual matrix formation leads to adverse remodelling of the heart. In this Review, Weber et al. discuss relevant mechanisms of cardiac fibrosis and consequent remodelling, and highlight potential strategies for cardioprotection. Abstract | Full Text | PDF
Vascular access and closure in coronary angiography and percutaneous intervention Robert A. Byrne, Salvatore Cassese, Maryam Linhardt & Adnan Kastrati Published online: 27 November 2012 p27 | doi:10.1038/nrcardio.2012.160 The success of transcatheter therapeutics relies heavily on the choice of vascular access site and on adequate arteriotomy closure. In this article, Byrne and colleagues review the state-of-the-art and future developments in vascular closure devices. They also compare the safety and efficacy of radial artery and femoral artery access for diagnostic and interventional procedures. Abstract | Full Text | PDF
Timely and optimal treatment of patients with STEMI Jens F. Lassen, Hans E. Bøtker & Christian J. Terkelsen Published online: 20 November 2012 p41 | doi:10.1038/nrcardio.2012.156 Timeliness of reperfusion is paramount in the management of patients with ST segment elevation myocardial infarction. Both fibrinolysis and primary percutaneous coronary intervention are inherently associated with patient and health-care system delays. In this Review, Jens F. Lassen and colleagues describe the types of delay to reperfusion and their effects on outcome, and discuss strategies to optimize reperfusion therapy in these patients. Abstract | Full Text | PDF
Screening for rheumatic heart disease: current approaches and controversies Kathryn Roberts, Samantha Colquhoun, Andrew Steer, Bo Reményi & Jonathan Carapetis Published online: 13 November 2012 p49 | doi:10.1038/nrcardio.2012.157 Rheumatic heart disease (RHD) is preventable, yet continues to be a leading cause of morbidity and mortality in children in developing countries. In this Review, Kathryn Roberts and colleagues examine whether RHD fulfils the 1994 Council of Europe criteria for a disease suitable for screening, assess cardiac auscultation and echocardiography as methods of screening for RHD, and discuss areas of controversy that require further research in order to make recommendations about screening for this disease. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2011. Nature Reviews Cardiology was previously published as Nature Clinical Practice Cardiovascular Medicine.

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