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2013/01/07

Acta Pharmacologica Sinica - Table of Contents alert Volume 34 Issue 1


Special Feature: Stroke


TABLE OF CONTENTS

Volume 34, Issue 1 (January 2013)

Special Feature: Stroke

This issue covers our current understanding of the pathophysiological roles of the ion channels and exchangers involved in non-glutamate mechanisms in cerebral ischemia and stroke, as well as their potential for therapeutic intervention. These non-glutamate mechanisms include TRP channels, KATP channels, chloride channels, acid-sensing ion channels, hemichannels, volume-regulated anion channels, adenosine receptors, nitrogen species, neural precursor cells, retinal ischemia, and neuron glial cells. The articles highlight novel therapeutic strategies for targeting non-glutamate mechanisms to prevent neuronal damage in stroke and to promote neuronal survival, regeneration and functional recovery after stroke, thus providing long-term economic, social, and healthcare benefits worldwide.

In this issue
Editorial
Research Highlights
Reviews
Original Articles

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The January 2013 of APS (Acta Pharmacologica Sinica) contains a special section on stroke, which covers our current understanding of the pathophysiological roles of the ion channels and exchangers involved in non-glutamate mechanisms in cerebral ischemia and stroke, as well as their potential for therapeutic intervention.
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Editorial

Top

Current mechanisms in stroke

Hong-shuo Sun

Acta Pharmacol Sin 2013 34: 1-2; advance online publication, December 24, 2012; 10.1038/aps.2012.174

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Research Highlights

Top

Restoring neuroprotection through a new preclinical paradigm: translational success for NA-1 in stroke therapy

Ryan Instrum and Hong-shuo Sun

Acta Pharmacol Sin 2013 34: 3-5; advance online publication, December 24, 2012; 10.1038/aps.2012.175

Full Text | PDF

The good and bad of microglia/macrophages: new hope in stroke therapeutics

Ya-chi Huang and Zhong-ping Feng

Acta Pharmacol Sin 2013 34: 6-7; advance online publication, December 24, 2012; 10.1038/aps.2012.178

Full Text | PDF

Dietary salt intake and stroke

Ekaterina Turlova and Zhong-ping Feng

Acta Pharmacol Sin 2013 34: 8-9; advance online publication, December 31, 2012; 10.1038/aps.2012.179

Full Text | PDF

Reviews

Top

Current understanding of TRPM7 pharmacology and drug development for stroke

Christine You Jin Bae and Hong-shuo Sun

Acta Pharmacol Sin 2013 34: 10-16; advance online publication, July 23, 2012; 10.1038/aps.2012.94

Abstract | Full Text

Chloride channels in stroke

Ya-ping Zhang, Hao Zhang and Dayue Darrel Duan

Acta Pharmacol Sin 2013 34: 17-23; advance online publication, October 29, 2012; 10.1038/aps.2012.140

Abstract | Full Text

Neuroprotective role of ATP-sensitive potassium channels in cerebral ischemia

Hong-shuo Sun and Zhong-ping Feng

Acta Pharmacol Sin 2013 34: 24-32; advance online publication, November 5, 2012; 10.1038/aps.2012.138

Abstract | Full Text

The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke intervention

Tian-dong Leng and Zhi-gang Xiong

Acta Pharmacol Sin 2013 34: 33-38; advance online publication, July 23, 2012; 10.1038/aps.2012.81

Abstract | Full Text

Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction

Nicholas L Weilinger, Valentyna Maslieieva, Jennifer Bialecki, Sarup S Sridharan, Peter L Tang and Roger J Thompson

Acta Pharmacol Sin 2013 34: 39-48; advance online publication, August 6, 2012; 10.1038/aps.2012.95

Abstract | Full Text

Loss of endoplasmic reticulum Ca2+ homeostasis: contribution to neuronal cell death during cerebral ischemia

Ankur Bodalia, Hongbin Li and Michael F Jackson

Acta Pharmacol Sin 2013 34: 49-59; advance online publication, October 29, 2012; 10.1038/aps.2012.139

Abstract | Full Text

Regulation of adenosine levels during cerebral ischemia

Stephanie Chu, Wei Xiong, Dali Zhang, Hanifi Soylu, Chao Sun, Benedict C Albensi and Fiona E Parkinson

Acta Pharmacol Sin 2013 34: 60-66; advance online publication, October 15, 2012; 10.1038/aps.2012.127

Abstract | Full Text

Targeting reactive nitrogen species: a promising therapeutic strategy for cerebral ischemia-reperfusion injury

Xing-miao Chen, Han-sen Chen, Ming-jing Xu and Jian-gang Shen

Acta Pharmacol Sin 2013 34: 67-77; advance online publication, July 30, 2012; 10.1038/aps.2012.82

Abstract | Full Text

Role of neural precursor cells in promoting repair following stroke

Pooya Dibajnia and Cindi M Morshead

Acta Pharmacol Sin 2013 34: 78-90; advance online publication, October 15, 2012; 10.1038/aps.2012.107

Abstract | Full Text

What can we learn about stroke from retinal ischemia models?

Philippe M D'Onofrio and Paulo D Koeberle

Acta Pharmacol Sin 2013 34: 91-103; advance online publication, December 3, 2012; 10.1038/aps.2012.165

Abstract | Full Text

Original Articles

Top

A novel approach to induction and rehabilitation of deficits in forelimb function in a rat model of ischemic stroke

Jessica Mary Livingston-Thomas, Andrew Wilson Hume, Tracy Ann Doucette and Richard Andrew Tasker

Acta Pharmacol Sin 2013 34: 104-112; advance online publication, October 29, 2012; 10.1038/aps.2012.106

Abstract | Full Text

Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury

Ammar Alibrahim, Li-yan Zhao, Christine You-jin Bae, Andrew Barszczyk, Christopher Lf Sun, Guan-lei Wang and Hong-shuo Sun

Acta Pharmacol Sin 2013 34: 113-118; advance online publication, December 3, 2012; 10.1038/aps.2012.148

Abstract | Full Text

WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats

Jing Sun, Yin-quan Fang, Hong Ren, Tao Chen, Jing-jing Guo, Jun Yan, Shu Song, Lu-yong Zhang and Hong Liao

Acta Pharmacol Sin 2013 34: 119-128; advance online publication, December 3, 2012; 10.1038/aps.2012.141

Abstract | Full Text

Voltage-gated K+ channels in adipogenic differentiation of bone marrow-derived human mesenchymal stem cells

Mi-hyeon You, Min Seok Song, Seul Ki Lee, Pan Dong Ryu, So Yeong Lee and Dae-yong Kim

Acta Pharmacol Sin 2013 34: 129-136; advance online publication, December 10, 2012; 10.1038/aps.2012.142

Abstract | Full Text

Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation

Jian Liu, Jing-fang Zhang, Jin-zhi Lu, De-ling Zhang, Ke Li, Ke Su, Jing Wang, Ye-min Zhang, Nian Wang, Si-tu Yang, Lang Bu and Jing-ping Ou-yang

Acta Pharmacol Sin 2013 34: 137-145; advance online publication, October 29, 2012; 10.1038/aps.2012.133

Abstract | Full Text

CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells

Ewa Augustin, Barbara Borowa-Mazgaj, Agnieszka Kikulska, Milena Kordalewska and Monika Pawłowska

Acta Pharmacol Sin 2013 34: 146-156; advance online publication, November 19, 2012; 10.1038/aps.2012.132

Abstract | Full Text

Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells

Hai-yan Hu, Kun-peng Li, Xiu-ju Wang, Yuan Liu, Zhi-gang Lu, Rui-hong Dong, Hong-bo Guo and Mei-xia Zhang

Acta Pharmacol Sin 2013 34: 157-166; advance online publication, December 17, 2012; 10.1038/aps.2012.161

Abstract | Full Text

Construction of lentivirus-based inhibitor of hsa-microRNA-338-3p with specific secondary structure

Kai Sun, Chen Guo, Hai-jun Deng, Jing-qing Dong, Shang-tong Lei and Guo-xin Li

Acta Pharmacol Sin 2013 34: 167-175; advance online publication, December 3, 2012; 10.1038/aps.2012.172

Abstract | Full Text

Galectin-3 gene silencing inhibits migration and invasion of human tongue cancer cells in vitro via downregulating β-catenin

Dong Zhang, Zheng-gang Chen, Shao-hua Liu, Zuo-qing Dong, Martin Dalin, Shi-san Bao, Ying-wei Hu and Feng-cai Wei

Acta Pharmacol Sin 2013 34: 176-184; advance online publication, October 29, 2012; 10.1038/aps.2012.150

Abstract | Full Text

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