Special Feature: Stroke | |  | |  |
TABLE OF CONTENTS |  |  |  | Volume 34, Issue 1 (January 2013) Special Feature: Stroke This issue covers our current understanding of the pathophysiological roles of the ion channels and exchangers involved in non-glutamate mechanisms in cerebral ischemia and stroke, as well as their potential for therapeutic intervention. These non-glutamate mechanisms include TRP channels, KATP channels, chloride channels, acid-sensing ion channels, hemichannels, volume-regulated anion channels, adenosine receptors, nitrogen species, neural precursor cells, retinal ischemia, and neuron glial cells. The articles highlight novel therapeutic strategies for targeting non-glutamate mechanisms to prevent neuronal damage in stroke and to promote neuronal survival, regeneration and functional recovery after stroke, thus providing long-term economic, social, and healthcare benefits worldwide. |  | In this issue Editorial Research Highlights Reviews Original Articles
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| |  |  |  | | Advertisement |  | The January 2013 of APS (Acta Pharmacologica Sinica) contains a special section on stroke, which covers our current understanding of the pathophysiological roles of the ion channels and exchangers involved in non-glutamate mechanisms in cerebral ischemia and stroke, as well as their potential for therapeutic intervention. Access the Special Issue on Stroke today! | |  | | | Editorial | Top |  | Current mechanisms in stroke Hong-shuo Sun Acta Pharmacol Sin 2013 34: 1-2; advance online publication, December 24, 2012; 10.1038/aps.2012.174 Full Text | PDF |  | Research Highlights | Top |  | Restoring neuroprotection through a new preclinical paradigm: translational success for NA-1 in stroke therapy Ryan Instrum and Hong-shuo Sun Acta Pharmacol Sin 2013 34: 3-5; advance online publication, December 24, 2012; 10.1038/aps.2012.175 Full Text | PDF |  |  |  | The good and bad of microglia/macrophages: new hope in stroke therapeutics Ya-chi Huang and Zhong-ping Feng Acta Pharmacol Sin 2013 34: 6-7; advance online publication, December 24, 2012; 10.1038/aps.2012.178 Full Text | PDF |  |  |  | Dietary salt intake and stroke Ekaterina Turlova and Zhong-ping Feng Acta Pharmacol Sin 2013 34: 8-9; advance online publication, December 31, 2012; 10.1038/aps.2012.179 Full Text | PDF |  | Reviews | Top |  | Current understanding of TRPM7 pharmacology and drug development for stroke Christine You Jin Bae and Hong-shuo Sun Acta Pharmacol Sin 2013 34: 10-16; advance online publication, July 23, 2012; 10.1038/aps.2012.94 Abstract | Full Text |  |  |  | Chloride channels in stroke Ya-ping Zhang, Hao Zhang and Dayue Darrel Duan Acta Pharmacol Sin 2013 34: 17-23; advance online publication, October 29, 2012; 10.1038/aps.2012.140 Abstract | Full Text |  |  |  | Neuroprotective role of ATP-sensitive potassium channels in cerebral ischemia Hong-shuo Sun and Zhong-ping Feng Acta Pharmacol Sin 2013 34: 24-32; advance online publication, November 5, 2012; 10.1038/aps.2012.138 Abstract | Full Text |  |  |  | The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke intervention Tian-dong Leng and Zhi-gang Xiong Acta Pharmacol Sin 2013 34: 33-38; advance online publication, July 23, 2012; 10.1038/aps.2012.81 Abstract | Full Text |  |  |  | Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction Nicholas L Weilinger, Valentyna Maslieieva, Jennifer Bialecki, Sarup S Sridharan, Peter L Tang and Roger J Thompson Acta Pharmacol Sin 2013 34: 39-48; advance online publication, August 6, 2012; 10.1038/aps.2012.95 Abstract | Full Text |  |  |  | Loss of endoplasmic reticulum Ca2+ homeostasis: contribution to neuronal cell death during cerebral ischemia Ankur Bodalia, Hongbin Li and Michael F Jackson Acta Pharmacol Sin 2013 34: 49-59; advance online publication, October 29, 2012; 10.1038/aps.2012.139 Abstract | Full Text |  |  |  | Regulation of adenosine levels during cerebral ischemia Stephanie Chu, Wei Xiong, Dali Zhang, Hanifi Soylu, Chao Sun, Benedict C Albensi and Fiona E Parkinson Acta Pharmacol Sin 2013 34: 60-66; advance online publication, October 15, 2012; 10.1038/aps.2012.127 Abstract | Full Text |  |  |  | Targeting reactive nitrogen species: a promising therapeutic strategy for cerebral ischemia-reperfusion injury Xing-miao Chen, Han-sen Chen, Ming-jing Xu and Jian-gang Shen Acta Pharmacol Sin 2013 34: 67-77; advance online publication, July 30, 2012; 10.1038/aps.2012.82 Abstract | Full Text |  |  |  | Role of neural precursor cells in promoting repair following stroke Pooya Dibajnia and Cindi M Morshead Acta Pharmacol Sin 2013 34: 78-90; advance online publication, October 15, 2012; 10.1038/aps.2012.107 Abstract | Full Text |  |  |  | What can we learn about stroke from retinal ischemia models? Philippe M D'Onofrio and Paulo D Koeberle Acta Pharmacol Sin 2013 34: 91-103; advance online publication, December 3, 2012; 10.1038/aps.2012.165 Abstract | Full Text |  | Original Articles | Top |  | A novel approach to induction and rehabilitation of deficits in forelimb function in a rat model of ischemic stroke Jessica Mary Livingston-Thomas, Andrew Wilson Hume, Tracy Ann Doucette and Richard Andrew Tasker Acta Pharmacol Sin 2013 34: 104-112; advance online publication, October 29, 2012; 10.1038/aps.2012.106 Abstract | Full Text |  |  |  | Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury Ammar Alibrahim, Li-yan Zhao, Christine You-jin Bae, Andrew Barszczyk, Christopher Lf Sun, Guan-lei Wang and Hong-shuo Sun Acta Pharmacol Sin 2013 34: 113-118; advance online publication, December 3, 2012; 10.1038/aps.2012.148 Abstract | Full Text |  |  |  | WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats Jing Sun, Yin-quan Fang, Hong Ren, Tao Chen, Jing-jing Guo, Jun Yan, Shu Song, Lu-yong Zhang and Hong Liao Acta Pharmacol Sin 2013 34: 119-128; advance online publication, December 3, 2012; 10.1038/aps.2012.141 Abstract | Full Text |  |  |  | Voltage-gated K+ channels in adipogenic differentiation of bone marrow-derived human mesenchymal stem cells Mi-hyeon You, Min Seok Song, Seul Ki Lee, Pan Dong Ryu, So Yeong Lee and Dae-yong Kim Acta Pharmacol Sin 2013 34: 129-136; advance online publication, December 10, 2012; 10.1038/aps.2012.142 Abstract | Full Text |  |  |  | Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation Jian Liu, Jing-fang Zhang, Jin-zhi Lu, De-ling Zhang, Ke Li, Ke Su, Jing Wang, Ye-min Zhang, Nian Wang, Si-tu Yang, Lang Bu and Jing-ping Ou-yang Acta Pharmacol Sin 2013 34: 137-145; advance online publication, October 29, 2012; 10.1038/aps.2012.133 Abstract | Full Text |  |  |  | CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells Ewa Augustin, Barbara Borowa-Mazgaj, Agnieszka Kikulska, Milena Kordalewska and Monika Pawłowska Acta Pharmacol Sin 2013 34: 146-156; advance online publication, November 19, 2012; 10.1038/aps.2012.132 Abstract | Full Text |  |  |  | Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells Hai-yan Hu, Kun-peng Li, Xiu-ju Wang, Yuan Liu, Zhi-gang Lu, Rui-hong Dong, Hong-bo Guo and Mei-xia Zhang Acta Pharmacol Sin 2013 34: 157-166; advance online publication, December 17, 2012; 10.1038/aps.2012.161 Abstract | Full Text |  |  |  | Construction of lentivirus-based inhibitor of hsa-microRNA-338-3p with specific secondary structure Kai Sun, Chen Guo, Hai-jun Deng, Jing-qing Dong, Shang-tong Lei and Guo-xin Li Acta Pharmacol Sin 2013 34: 167-175; advance online publication, December 3, 2012; 10.1038/aps.2012.172 Abstract | Full Text |  |  |  | Galectin-3 gene silencing inhibits migration and invasion of human tongue cancer cells in vitro via downregulating β-catenin Dong Zhang, Zheng-gang Chen, Shao-hua Liu, Zuo-qing Dong, Martin Dalin, Shi-san Bao, Ying-wei Hu and Feng-cai Wei Acta Pharmacol Sin 2013 34: 176-184; advance online publication, October 29, 2012; 10.1038/aps.2012.150 Abstract | Full Text |  |  |  |  |  | | Advertisement |  | Ensure your access If you are unable to access the articles in this alert, your library may not subscribe to this journal. 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