Next Generation Sequencing Newsletter January 2013

Next Generation Sequencing Newsletter

January 2013

NextGenSeq@nature.com provides a feel for the current state of the art in next generation sequencing technologies and how these platforms are changing the face of biomedical research. The page hosts a collection of original research, commentary and reviews published by Nature Publishing Group. Sign up for monthly e-alerts from Next Generation Sequencing.

Highlighted articles Access these articles for FREE by visiting NextGenSeq@nature.com   Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing FREE Mainul Hoque, Zhe Ji, Dinghai Zheng, Wenting Luo, Wencheng Li, Bei You, Ji Yeon Park, Ghassan Yehia & Bin Tian Nature Methods doi:10.1038/nmeth.2288   ERRATUM: Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome FREE Bai Jiang, Xujun Liang, Yang Chen, Tao Ma, Liyang Liu, Junfeng Li, Rui Jiang, Ting Chen, Xuegong Zhang & Shao Li Scientific Reports doi:10.1038/srep01019   ChIP-Seq identification of weakly conserved heart enhancers FREE Matthew J Blow, David J McCulley, Zirong Li, Tao Zhang, Jennifer A Akiyama, Amy Holt, Ingrid Plajzer-Frick, Malak Shoukry, Crystal Wright, Feng Chen, Veena Afzal, James Bristow, Bing Ren, Brian L Black, Edward M Rubin, Axel Visel & Len A Pennacchio Nature Genetics doi:10.1038/ng.650   The cultural revolution FREE Nature Reviews Microbiology doi:10.1038/nrmicro2948 NPG journal-based collections of interest   Applications of next–generation sequencing (Series in Nature Reviews Genetics)   Focus on Next-Generation Sequencing (Supplement from Nature Biotechnology) Recent articles from NPG Access these articles by visiting NextGenSeq@nature.com   Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer Elise Ruark, Katie Snape, Peter Humburg, Chey Loveday, Ilirjana Bajrami, Rachel Brough, Daniel Nava Rodrigues, Anthony Renwick, Sheila Seal, Emma Ramsay, Silvana Del Vecchio Duarte, Manuel A. Rivas, Margaret Warren-Perry, Anna Zachariou, Adriana Campion-Flora, Sandra Hanks, Anne Murray, Naser Ansari Pour, Jenny Douglas, Lorna Gregory, Andrew Rimmer, Neil M. Walker, Tsun-Po Yang, Julian W. Adlard, Julian Barwell, Jonathan Berg, Angela F. Brady, Carole Brewer, Glen Brice, Cyril Chapman, Jackie Cook, Rosemarie Davidson, Alan Donaldson, Fiona Douglas, Diana Eccles, D. Gareth Evans, Lynn Greenhalgh, Alex Henderson, Louise Izatt, Ajith Kumar, Fiona Lalloo, Zosia Miedzybrodzka, Patrick J. Morrison, Joan Paterson, Mary Porteous, Mark T. Rogers, Susan Shanley, Lisa Walker, Martin Gore, Richard Houlston, Matthew A. Brown, Mark J. Caufield, Panagiotis Deloukas, Mark I. McCarthy, John A. Todd, Clare Turnbull, Jorge S. Reis-Filho, Alan Ashworth, Antonis C. Antoniou, Christopher J. Lord, Peter Donnelly, Nazneen Rahman Nature doi:10.1038/nature11725   Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans Ryan J Taft, Cas Simons, Satu Nahkuri, Harald Oey, Darren J Korbie, Timothy R Mercer, Jeff Holst, William Ritchie, Justin J-L Wong, John EJ Rasko, Daniel S Rokhsar, Bernard M Degnan & John S Mattick Nature Structural & Molecular Biology doi:10.1038/nsmb.1841   Conserved role of intragenic DNA methylation in regulating alternative promoters Alika K. Maunakea, Raman P. Nagarajan, Mikhail Bilenky, Tracy J. Ballinger, Cletus D'Souza, Shaun D. Fouse, Brett E. Johnson, Chibo Hong, Cydney Nielsen, Yongjun Zhao, Gustavo Turecki, Allen Delaney, Richard Varhol, Nina Thiessen, Ksenya Shchors, Vivi M. Heine, David H. Rowitch, Xiaoyun Xing, Chris Fiore, Maximiliaan Schillebeeckx, Steven J. M. Jones, David Haussler, Marco A. Marra, Martin Hirst, Ting Wang & Joseph F. Costello Nature doi:10.1038/nature09165   Food biotechnology: Good milk, bad milk Felix Cheung Nature China doi:10.1038/nchina.2010.74   Genome-wide analysis reveals a novel autosomal-recessive hearing loss locus DFNB80 on chromosome 2p16.1-p21 Mohamed Ali Mosrati, Isabelle Schrauwen, Mariem Ben Saiid, Mounira Aifa-Hmani, Erik Fransen, Malek Mneja, Abdelmonem Ghorbel, Guy Van Camp & Saber Masmoudi Journal of Human Genetics doi:10.1038/jhg.2012.141   FMRP targets distinct mRNA sequence elements to regulate protein expression Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B. Miller, Jeffrey D. Nusbaum, David L. Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner, Zev Williams, Uwe Ohler & Thomas Tuschl Nature doi:10.1038/nature11737

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