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2013/09/24

Scientific Reports Table of Contents e-alert: 24 September 2013

  24 September 2013   
 
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Biological Sciences top
 
 
 
 
 
 
 

Connexin43 Functions as a Novel Interacting Partner of Heat Shock Cognate Protein 70

 
 

Tomoya Hatakeyama, Ping Dai, Yoshinori Harada et al.

 
 

Regulation of connexin43 (Cx43) expression affects cell proliferation, differentiation and apoptosis in a gap junctional intercellular communication (GJIC)-independent manner. …

 
 
 
 
 
 

Pharmacologically Controlled Protein Switch for ON-OFF Regulation of Growth Factor Activity

 
 

Maria Karlsson, Balder Rebmann, Philipp S. Lienemann et al.

 
 

The precise manipulation of growth factor signaling is central to the progress of tissue engineering. Methods for direct time-resolved activation of signaling pathways through …

 
 
 
 
 
 

Information Measure for Long-Range Correlated Sequences: the Case of the 24 Human Chromosomes

 
 

A. Carbone

 
 

A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to …

 
 
 
 
 
 

Transgenerational sex determination: the embryonic environment experienced by a male affects offspring sex ratio

 
 

Daniel A. Warner, Tobias Uller, Richard Shine

 
 

Conditions experienced during embryonic development can have lasting effects, even carrying across generations. Most evidence for transgenerational effects comes from studies of …

 
 
 
 
 
 

Early-light embryonic stimulation suggests a second route, via gene activation, to cerebral lateralization in vertebrates

 
 

Cinzia Chiandetti, Jessica Galliussi, Richard J. Andrew et al.

 
 

Genetic factors determine the asymmetrical position of vertebrate embryos allowing asymmetric environmental stimulation to shape cerebral lateralization. In birds, late-light …

 
 
 
 
 
 

Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2

 
 

Pritha Bhattacharjee, Somnath Paul, Mayukh Banerjee et al.

 
 

The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with regard to the homozygous deletion of the gene (GSTM1

 
 
 
 
 
 

Dynamically correlated mutations drive human Influenza A evolution

 
 

F. Tria, S. Pompei, V. Loreto

 
 

Human Influenza A virus undergoes recurrent changes in the hemagglutinin (HA) surface protein, primarily involved in the human antibody recognition. Relevant antigenic changes, …

 
 
 
 
 
 

A computational approach to chemical etiologies of diabetes

 
 

Karine Audouze, Søren Brunak, Philippe Grandjean

 
 

Computational meta-analysis can link environmental chemicals to genes and proteins involved in human diseases, thereby elucidating possible etiologies and pathogeneses of …

 
 
 
 
 
 

Anti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease

 
 

Katarina Jovanovic, Danielle Gonsalves, Bianca Da Costa Dias et al.

 
 

Alzheimer's disease (AD) is the most prevalent form of dementia. The amyloid beta (Aβ) peptide is the predominant candidate aetiological agent and is generated through the …

 
 
 
 
 
 

Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity

 
 

Bianca Da Costa Dias, Katarina Jovanovic, Danielle Gonsalves et al.

 
 

Alzheimer's disease (AD) is characterized by neurofibrillary tangles, senile plaques and neuronal loss. Amyloid beta (Aβ) is proposed to elicit neuronal loss through cell surface …

 
 
 
 
 
 

The impact of human-environment interactions on the stability of forest-grassland mosaic ecosystems

 
 

Clinton Innes, Madhur Anand, Chris T. Bauch

 
 

Forest-grassland mosaic ecosystems can exhibit alternative stables states, whereby under the same environmental conditions, the ecosystem could equally well reside either in one …

 
 
 
 
 
 

Nephrons require Rho-kinase for proximal-distal polarity development

 
 

Nils O. Lindström, Peter Hohenstein, Jamie A. Davies

 
 

Epithelial tubules must have the right length and pattern for proper function. In the nephron, planar cell polarity controls elongation along the proximal-distal axis. As the …

 
 
 
 
 
 

Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties

 
 

Joseph H. Taube, Gabriel G. Malouf, Emily Lu et al.

 
 

The epithelial-mesenchymal transition (EMT) imparts metastatic competence on otherwise non-metastatic cancer cells through decreased inter-cellular adhesions, increased migratory …

 
 
 
 
 
 

Good Agreements Make Good Friends

 
 

The Anh Han, Luís Moniz Pereira, Francisco C. Santos et al.

 
 

When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the …

 
 
 
 
 
 

Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation

 
 

Robert A. Whittington, Alexis Bretteville, László Virág et al.

 
 

Several anesthetics have been reported to suppress the transcription of a number of genes, including Arc, also known as Arg3.1, an immediate early gene that plays a significant …

 
 
 
 
 
 

Subicular activation preceding hippocampal ripples in vitro

 
 

Hiroaki Norimoto, Nobuyoshi Matsumoto, Takeyuki Miyawaki et al.

 
 

Sharp wave-ripple complexes (SW-Rs), a transient form of high-frequency field oscillations observed in the hippocampus, are thought to mediate memory consolidation. They are …

 
 
 
 
 
 

Music Cognition as Mental Time Travel

 
 

Freya Bailes, Roger T. Dean, Marcus T. Pearce

 
 

As we experience a temporal flux of events our expectations of future events change. Such expectations seem to be central to our perception of affect in music, but we have little …

 
 
 
 
 
 

Hypoxia Enhances Chondrogenesis and Prevents Terminal Differentiation through PI3K/Akt/FoxO Dependent Anti-Apoptotic Effect

 
 

Hsieh-Hsing Lee, Chia-Chi Chang, Ming-Jium Shieh et al.

 
 

Hypoxia, a common environmental condition, influences cell signals and functions. Here, we compared the effects of hypoxia (1% oxygen) and normoxia (air) on chondrogenic …

 
 
 
 
 
 

SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation

 
 

Kiwamu Takemoto, Tomoki Matsuda, Naoki Sakai et al.

 
 

Chromophore-assisted light inactivation (CALI) is a powerful technique for acute perturbation of biomolecules in a spatio-temporally defined manner in living specimen with …

 
 
 
 
 
 

In situ recognition of cell-surface glycans and targeted imaging of cancer cells

 
 

Xiao-Ding Xu, Han Cheng, Wei-Hai Chen et al.

 
 

Fluorescent sensors capable of recognizing cancer-associated glycans, such as sialyl Lewis X (sLex) tetrasaccharide, have great potential for cancer diagnosis and therapy. Studies …

 
 
 
 
 
 
 
 
SciBX is pleased to present:
SciBX Summit on Innovation in Drug Discovery and Development 2013
October 29-30, 2013
The Colonnade Hotel, Boston, MA, USA
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Chemical Sciences top
 
 
 
 
 
 
 

Ordered mesoporous porphyrinic carbons with very high electrocatalytic activity for the oxygen reduction reaction

 
 

Jae Yeong Cheon, Taeyoung Kim, YongMan Choi et al.

 
 

The high cost of the platinum-based cathode catalysts for the oxygen reduction reaction (ORR) has impeded the widespread application of polymer electrolyte fuel cells. We report …

 
 
 
 
 
 

Visible-light-driven photoelectrochemical and photocatalytic performances of Cr-doped SrTiO3/TiO2 heterostructured nanotube arrays

 
 

Zhengbo Jiao, Tao Chen, Jinyan Xiong et al.

 
 

Well-aligned TiO2 nanotube arrays have become of increasing significance because of their unique highly ordered array structure, high specific surface area, unidirectional charge …

 
 
 
 
 
 

Origin of New Broad Raman D and G Peaks in Annealed Graphene

 
 

Jinpyo Hong, Min Kyu Park, Eun Jung Lee et al.

 
 

Since graphene, a single sheet of graphite, has all of its carbon atoms on the surface, its property is very sensitive to materials contacting the surface. Herein, we report novel …

 
 
 
 
 
 

Ultrahigh humidity sensitivity of graphene oxide

 
 

Hengchang Bi, Kuibo Yin, Xiao Xie et al.

 
 

Humidity sensors have been extensively used in various fields, and numerous problems are encountered when using humidity sensors, including low sensitivity, long response and …

 
 
 
 
 
 

Single-crystalline, wormlike hematite photoanodes for efficient solar water splitting

 
 

Jae Young Kim, Ganesan Magesh, Duck Hyun Youn et al.

 
 

A hematite photoanode showing a stable, record-breaking performance of 4.32 mA/cm2 photoelectrochemical water oxidation current at 1.23 V vs. RHE under simulated 1-sun (100 mW/cm2

 
 
 
 
 
 
 
 
Physical Sciences top
 
 
 
 
 
 
 

High-temperature thermoelectric transport at small scales: Thermal generation, transport and recombination of minority carriers

 
 

Gokhan Bakan, Niaz Khan, Helena Silva et al.

 
 

Thermoelectric transport in semiconductors is usually considered under small thermal gradients and when it is dominated by the role of the majority carriers. Not much is known …

 
 
 
 
 
 

Reciprocity of weighted networks

 
 

Tiziano Squartini, Francesco Picciolo, Franco Ruzzenenti et al.

 
 

In directed networks, reciprocal links have dramatic effects on dynamical processes, network growth, and higher-order structures such as motifs and communities. While the …

 
 
 
 
 
 

Giant photoluminescence emission in crystalline faceted Si grains

 
 

Giuseppe Faraci, Agata R. Pennisi, Alessandra Alberti et al.

 
 

Empowering an indirect band-gap material like Si with optical functionalities, firstly light emission, represents a huge advancement constantly pursued in the realization of any …

 
 
 
 
 
 

Micromechanics of emergent patterns in plastic flows

 
 

Santidan Biswas, Martin Grant, Indradev Samajdar et al.

 
 

Crystalline solids undergo plastic deformation and subsequently flow when subjected to stresses beyond their elastic limit. In nature most crystalline solids exist in …

 
 
 
 
 
 

Ordered mesoporous porphyrinic carbons with very high electrocatalytic activity for the oxygen reduction reaction

 
 

Jae Yeong Cheon, Taeyoung Kim, YongMan Choi et al.

 
 

The high cost of the platinum-based cathode catalysts for the oxygen reduction reaction (ORR) has impeded the widespread application of polymer electrolyte fuel cells. We report …

 
 
 
 
 
 

Versatile multi-wavelength ultrafast fiber laser mode-locked by carbon nanotubes

 
 

Xueming Liu, Dongdong Han, Zhipei Sun et al.

 
 

Multi-wavelength lasers have widespread applications (e.g. fiber telecommunications, pump-probe measurements, terahertz generation). Here, we report a nanotube-mode-locked …

 
 
 
 
 
 

Information Measure for Long-Range Correlated Sequences: the Case of the 24 Human Chromosomes

 
 

A. Carbone

 
 

A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to …

 
 
 
 
 
 

Designed Synthesis of Transition Metal/Oxide Hierarchical Peapods Array with the Superior Lithium Storage Performance

 
 

Huijuan Zhang, Yuanjuan Bai, Yan Zhang et al.

 
 

In this report, a novel hierarchical peapoded array with Co3O4 nanoparticles encapsulated in graphitized carbon fiber is introduced for the first time. The unique peapoded …

 
 
 
 
 
 

Visible-light-driven photoelectrochemical and photocatalytic performances of Cr-doped SrTiO3/TiO2 heterostructured nanotube arrays

 
 

Zhengbo Jiao, Tao Chen, Jinyan Xiong et al.

 
 

Well-aligned TiO2 nanotube arrays have become of increasing significance because of their unique highly ordered array structure, high specific surface area, unidirectional charge …

 
 
 
 
 
 

Origin of New Broad Raman D and G Peaks in Annealed Graphene

 
 

Jinpyo Hong, Min Kyu Park, Eun Jung Lee et al.

 
 

Since graphene, a single sheet of graphite, has all of its carbon atoms on the surface, its property is very sensitive to materials contacting the surface. Herein, we report novel …

 
 
 
 
 
 

Ultrahigh humidity sensitivity of graphene oxide

 
 

Hengchang Bi, Kuibo Yin, Xiao Xie et al.

 
 

Humidity sensors have been extensively used in various fields, and numerous problems are encountered when using humidity sensors, including low sensitivity, long response and …

 
 
 
 
 
 

Solution-Processed Nanoparticle Super-Float-Gated Organic Field-Effect Transistor as Un-cooled Ultraviolet and Infrared Photon Counter

 
 

Yongbo Yuan, Qingfeng Dong, Bin Yang et al.

 
 

High sensitivity photodetectors in ultraviolet (UV) and infrared (IR) range have broad civilian and military applications. Here we report on an un-cooled solution-processed UV-IR …

 
 
 
 
 
 

Can Google Trends search queries contribute to risk diversification?

 
 

Ladislav Kristoufek

 
 

Portfolio diversification and active risk management are essential parts of financial analysis which became even more crucial (and questioned) during and after the years of the …

 
 
 
 
 
 

Quantum Conductance in Silicon Oxide Resistive Memory Devices

 
 

A. Mehonic, A. Vrajitoarea, S. Cueff et al.

 
 

Resistive switching offers a promising route to universal electronic memory, potentially replacing current technologies that are approaching their fundamental limits. In many …

 
 
 
 
 
 

Dynamically correlated mutations drive human Influenza A evolution

 
 

F. Tria, S. Pompei, V. Loreto

 
 

Human Influenza A virus undergoes recurrent changes in the hemagglutinin (HA) surface protein, primarily involved in the human antibody recognition. Relevant antigenic changes, …

 
 
 
 
 
 

An experimental proposal for revealing contextuality in almost all qutrit states

 
 

Jayne Thompson, Robert Pisarczyk, Paweł Kurzyński et al.

 
 

Contextuality is a foundational phenomenon underlying key differences between quantum theory and classical realistic descriptions of the world. Here we propose an experimental …

 
 
 
 
 
 

Broadband energy transfer to sensitizing dyes by mobile quantum dot mediators in solar cells

 
 

Gede Widia Pratama Adhyaksa, Ga In Lee, Se-Woong Baek et al.

 
 

The efficiency of solar cells depends on absorption intensity of the photon collectors. Herein, mobile quantum dots (QDs) functionalized with thiol ligands in electrolyte are …

 
 
 
 
 
 

The impact of human-environment interactions on the stability of forest-grassland mosaic ecosystems

 
 

Clinton Innes, Madhur Anand, Chris T. Bauch

 
 

Forest-grassland mosaic ecosystems can exhibit alternative stables states, whereby under the same environmental conditions, the ecosystem could equally well reside either in one …

 
 
 
 
 
 

Sb2Se3 under pressure

 
 

Ilias Efthimiopoulos, Jiaming Zhang, Melvin Kucway et al.

 
 

Selected members of the A2B3 (A=Sb, Bi; B=Se, Te) family are topological insulators. The Sb2Se3 compound does not exhibit any topological properties at ambient conditions; a …

 
 
 
 
 
 

Creep rupture as a non-homogeneous Poissonian process

 
 

Zsuzsa Danku, Ferenc Kun

 
 

Creep rupture of heterogeneous materials occurring under constant sub-critical external loads is responsible for the collapse of engineering constructions and for natural …

 
 
 
 
 
 

Heavy fermion properties of the Kondo Lattice model

 
 

Steffen Sykora, Klaus W. Becker

 
 

We study the S=1/2 Kondo lattice model which is widely used to describe heavy fermion behavior. In conventional treatments of the model the Kondo interaction is decoupled in …

 
 
 
 
 
 

Room temperature rubbing for few-layer two-dimensional thin flakes directly on flexible polymer substrates

 
 

Yan Yu, Shenglin Jiang, Wenli Zhou et al.

 
 

The functional layers of few-layer two-dimensional (2-D) thin flakes on flexible polymers for stretchable applications have attracted much interest. However, most fabrication …

 
 
 
 
 
 

MnO Nanoparticle@Mesoporous Carbon Composites Grown on Conducting Substrates Featuring High-performance Lithium-ion Battery, Supercapacitor and Sensor

 
 

Tianyu Wang, Zheng Peng, Yuhang Wang et al.

 
 

We demonstrate a facile, two-step coating/calcination approach to grow a uniform MnO nanoparticle@mesoporous carbon (MnO@C) composite on conducting substrates, by direct coating …

 
 
 
 
 
 

Pitch sensation involves stochastic resonance

 
 

Stefan Martignoli, Florian Gomez, Ruedi Stoop

 
 

Pitch is a complex hearing phenomenon that results from elicited and self-generated cochlear vibrations. Read-off vibrational information is relayed higher up the auditory …

 
 
 
 
 
 

All Carbon-Based Photodetectors: An eminent integration of graphite quantum dots and two dimensional graphene

 
 

Shih-Hao Cheng, Tong-Min Weng, Meng-Lin Luet al.

 
 

Photodetectors with ultrahigh sensitivity based on the composite made with all carbon-based materials consisting of graphite quantum dots (QDs), and two dimensional graphene …

 
 
 
 
 
 

Diversity of individual mobility patterns and emergence of aggregated scaling laws

 
 

Xiao-Yong Yan, Xiao-Pu Han, Bing-Hong Wang et al.

 
 

Uncovering human mobility patterns is of fundamental importance to the understanding of epidemic spreading, urban transportation and other socioeconomic dynamics embodying …

 
 
 
 
 
 

Good Agreements Make Good Friends

 
 

The Anh Han, Luís Moniz Pereira, Francisco C. Santos et al.

 
 

When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the …

 
 
 
 
 
 

Ionization with low-frequency fields in the tunneling regime

 
 

J. Dura, N. Camus, A. Thai et al.

 
 

Strong-field ionisation surprises with richness beyond current understanding despite decade long investigations. Ionisation with mid-IR light has promptly revealed unexpected …

 
 
 
 
 
 

Atomic Scale Verification of Oxide-Ion Vacancy Distribution near a Single Grain Boundary in YSZ

 
 

Jihwan An, Joong Sun Park, Ai Leen Koh et al.

 
 

This study presents atomic scale characterization of grain boundary defect structure in a functional oxide with implications for a wide range of electrochemical and electronic …

 
 
 
 
 
 

Higher order harmonic detection for exploring nonlinear interactions with nanoscale resolution

 
 

R. K. Vasudevan, M. Baris Okatan, I. Rajapaksa et al.

 
 

Nonlinear dynamics underpin a vast array of physical phenomena ranging from interfacial motion to jamming transitions. In many cases, insight into the nonlinear behavior can be …

 
 
 
 
 
 

Single-crystalline, wormlike hematite photoanodes for efficient solar water splitting

 
 

Jae Young Kim, Ganesan Magesh, Duck Hyun Youn et al.

 
 

A hematite photoanode showing a stable, record-breaking performance of 4.32 mA/cm2 photoelectrochemical water oxidation current at 1.23 V vs. RHE under simulated 1-sun (100 mW/cm2

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

The impact of human-environment interactions on the stability of forest-grassland mosaic ecosystems

 
 

Clinton Innes, Madhur Anand, Chris T. Bauch

 
 

Forest-grassland mosaic ecosystems can exhibit alternative stables states, whereby under the same environmental conditions, the ecosystem could equally well reside either in one …

 
 
 
 
 
 

New approach for earthquake/tsunami monitoring using dense GPS networks

 
 

Xingxing Li, Maorong Ge, Yong Zhang et al.

 
 

In recent times increasing numbers of high-rate GPS stations have been installed around the world and set-up to provide data in real-time. These networks provide a great …

 
 
 
 
 
 
 
Health Sciences top
 
 
 
 
 
 
 

A computational approach to chemical etiologies of diabetes

 
 

Karine Audouze, Søren Brunak, Philippe Grandjean

 
 

Computational meta-analysis can link environmental chemicals to genes and proteins involved in human diseases, thereby elucidating possible etiologies and pathogeneses of …

 
 
 
 
 
 

Music Cognition as Mental Time Travel

 
 

Freya Bailes, Roger T. Dean, Marcus T. Pearce

 
 

As we experience a temporal flux of events our expectations of future events change. Such expectations seem to be central to our perception of affect in music, but we have little …

 
 
 
 
 
 

Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation

 
 

Robert A. Whittington, Alexis Bretteville, László Virág et al.

 
 

Several anesthetics have been reported to suppress the transcription of a number of genes, including Arc, also known as Arg3.1, an immediate early gene that plays a significant …

 
 
 
 
 
 

In situ recognition of cell-surface glycans and targeted imaging of cancer cells

 
 

Xiao-Ding Xu, Han Cheng, Wei-Hai Chen et al.

 
 

Fluorescent sensors capable of recognizing cancer-associated glycans, such as sialyl Lewis X (sLex) tetrasaccharide, have great potential for cancer diagnosis and therapy. Studies …

 
 
 
 
 
 
 
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