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2013/11/18

Nature Reviews Genetics Contents December 2013 Volume 14 Number 12 pp 821-894

Nature Reviews Genetics


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TABLE OF CONTENTS
 
December 2013 Volume 14 Number 12
Nature Reviews Genetics cover
Impact Factor 41.063 *
In this issue
Research Highlights
Reviews
Correspondence


Also this month
Article series:
Non-coding RNA
 Featured article:
Evolution of crop species: genetics of domestication and diversification
Rachel S. Meyer & Michael D. Purugganan
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RESEARCH HIGHLIGHTSTop

Small RNAs: Antiviral RNAi in mammals
p821 | doi:10.1038/nrg3616
PDF


Evolution: Proteins partner up in a vigorous relationship
p822 | doi:10.1038/nrg3617
PDF


Gene expression: Controls and roles for trans-splicing
p822 | doi:10.1038/nrg3618
PDF


Development: Seeing the pattern
p823 | doi:10.1038/nrg3619
PDF


Clinical genetics: Exomes in the clinic
p824 | doi:10.1038/nrg3620
PDF


Human evolution: Reprogrammed cells dissect ape retrotransposition
p824 | doi:10.1038/nrg3621
PDF


Gene regulation: From genetic variation to phenotype via chromatin
p824 | doi:10.1038/nrg3622
PDF



IN BRIEF

Gene regulation: Key role for translation in cell cycle control | Synthetic biology: Recoding bacterial genomes | Molecular evolution: Bypassing indels | Technology: Amplifying single-cell cDNA without bias | Regeneration: Key role for polyploidization in wound healing | Development: Enhancers 'fine-tune' face and skull shape | Cancer genomics: Explaining aneuploidy patterns
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REVIEWSTop
Genome dynamics during experimental evolution
Jeffrey E. Barrick & Richard E. Lenski
p827 | doi:10.1038/nrg3564
This Review describes how whole-genome sequencing of experimental populations of microorganisms and other species is yielding new insights into evolutionary processes. These details include variation in mutation rates, diverse genetic routes to adaptation and dynamic interactions within and between populations.
Abstract | Full Text | PDF
Evolution of crop species: genetics of domestication and diversification
Rachel S. Meyer & Michael D. Purugganan
p840 | doi:10.1038/nrg3605
The recent improvement in technologies to identify genetic variants linked with quantitative traits has allowed the identification of variants that are associated with crop domestication. This Review considers these approaches and their application to the study of crop domestication.
Abstract | Full Text | PDF | Supplementary information
A new world of Polycombs: unexpected partnerships and emerging functions
Yuri B. Schwartz & Vincenzo Pirrotta
p853 | doi:10.1038/nrg3603
Polycomb group (PcG) proteins have long been known to have repressive functions. Recently, novel complexes of PcG proteins have been identified and have been shown to have novel molecular and biological functions, which are discussed in this Review.
Abstract | Full Text | PDF
High-resolution network biology: connecting sequence with function
Colm J. Ryan, Peter Cimermancic, Zachary A. Szpiech, Andrej Sali, Ryan D. Hernandez & Nevan J. Krogan
p865 | doi:10.1038/nrg3574
Network analyses of protein-protein, genetic and drug-gene interactions have typically been limited to analyses at the whole-protein and whole-gene levels. This Review discusses how high-resolution network analyses at the domain and residue levels are providing valuable insights into diverse research fields that range from structural biology to human disease.
Abstract | Full Text | PDF
Article series: Non-coding RNA
Gene regulation by antisense transcription
Vicent Pelechano & Lars M. Steinmetz
p880 | doi:10.1038/nrg3594
Antisense transcription is increasingly being recognized as an important regulator of gene expression across all kingdoms of life and through a range of regulatory modes. Antisense transcripts are also emerging as facilitators of rapid evolution of gene regulation.
Abstract | Full Text | PDF
 
CORRESPONDENCETop
Correspondence: A commentary on Pitfalls of predicting complex traits from SNPs
Gustavo de los Campos & Daniel A. Sorensen
p894 | doi:10.1038/nrg3457-c1
Full Text | PDF
 
Top
Reply: Author reply to A commentary on Pitfalls of predicting complex traits from SNPs
Naomi R. Wray, Jian Yang, Ben J. Hayes, Alkes L. Price, Michael E. Goddard & Peter M. Visscher
p894 | doi:10.1038/nrg3457-c2
Full Text | PDF
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