Scientific Reports Table of Contents e-alert: 25 March 2014

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25 March 2014      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports             Jump to the content that matters to you ▼ Biological Sciences   ▼ Chemical Sciences   ▼ Physical Sciences   ▼ Earth & Environmental Sciences   ▼ Health Sciences               Biological Sciences ▲ top               Induction of nuclear translocation of mutant cytoplasmic p53 by geranylgeranoic acid in a human hepatoma cell line ▶     Chieko Iwao, Yoshihiro Shidoji     Mutant p53 proteins in human hepatoma cell lines such as HuH-7 (Y220C) and PLC/PRF/5 (R249S) accumulate in the cytoplasm, and lose their transcriptional function. Geranylgeranoic …             Label-Free Characterization of Emerging Human Neuronal Networks ▶     Mustafa Mir, Taewoo Kim, Anirban Majumder et al.     The emergent self-organization of a neuronal network in a developing nervous system is the result of a remarkably orchestrated process involving a multitude of chemical, …             Antidepressant-like effects of auraptenol in mice ▶     Xiaosu Gu, Yong Zhou, Xiaomei Wu et al.     Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Current available antidepressants are …             Long-Term Exposure to High Altitude Affects Voluntary Spatial Attention at Early and Late Processing Stages ▶     Yan Wang, Hailin Ma, Shimin Fu et al.     The neurocognitive basis of the effect of long-term high altitude exposure on voluntary attention is unclear. Using event related potentials, the high altitude group (people born …             Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state ▶     Daisuke Morito, Kouki Nishikawa, Jun Hoseki et al.     Moyamoya disease is an idiopathic human cerebrovascular disorder that is characterized by progressive stenosis and abnormal collateral vessels. We recently identified …             Internal translation initiation and eIF4F/ATP-independent scanning of mRNA by eukaryotic ribosomal particles ▶     Sultan Ch. Agalarov, Pavel A. Sakharov, Dina Kh. Fattakhova et al.     The recombinant mRNAs with 5′-untranslated region, called omega leader, of tobacco mosaic virus RNA are known to be well translated in eukaryotic cell-free systems, even if …             Diel nitrogen fixation pattern of Trichodesmium: the interactive control of light and Ni ▶     Irene B. Rodriguez, Tung-Yuan Ho     Trichodesmium, a nonheterocystous cyanobacterium widely abundant in the surface water of the tropical and subtropical ocean, fixes dinitrogen under high light conditions while …             HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors ▶     Xun Liu, Ankit Shah, Mohitkumar R. Gangwani et al.     The prevalence of HIV-associated neurocognitive disorders (HAND) remains high in patients infected with HIV-1. The production of pro-inflammatory cytokines by astrocytes/microglia …             Sound management may sequester methane in grazed rangeland ecosystems ▶     Chengjie Wang, Guodong Han, Shiping Wang et al.     Considering their contribution to global warming, the sources and sinks of methane (CH4) should be accounted when undertaking a greenhouse gas inventory for grazed rangeland …             Structure and Permeability of Ion-channels by Integrated AFM and Waveguide TIRF Microscopy ▶     Srinivasan Ramachandran, Fernando Teran Arce, Nirav R. Patel et al.     Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels …             Novel Multiplex MethyLight Protocol for Detection of DNA Methylation in Patient Tissues and Bodily Fluids ▶     Ekaterina Olkhov-Mitsel, Darko Zdravic, Ken Kron et al.     Aberrant DNA methylation is a hallmark of cancer and is an important potential biomarker. Particularly, combined analysis of a panel of hypermethylated genes shows the most …             Immune privilege of the CNS is not the consequence of limited antigen sampling ▶     Melissa G. Harris, Paul Hulseberg, Changying Ling et al.     Central nervous system (CNS) immune privilege is complex, and it is still not understood how CNS antigens are sampled by the peripheral immune system under steady state …             Information content and analysis methods for Multi-Modal High-Throughput Biomedical Data ▶     Bisakha Ray, Mikael Henaff, Sisi Ma et al.     The spectrum of modern molecular high-throughput assaying includes diverse technologies such as microarray gene expression, miRNA expression, proteomics, DNA methylation, among …             A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material ▶     Min-Hui Wu, Liang-Ze Wan, Yu-Qing Zhang     A novel sodium N-fatty acyl amino acid (SFAAA) surfactant was synthesized using pupa oil and pupa protein hydrolysates (PPH) from a waste product of the silk industry. The …             Innovative strategy with potential to increase hemodialysis efficiency and safety ▶     Hsiao-Chien Chen, Hsiu-Chen Lin, Hsi-Hsien Chen et al.     Uremic toxins are mainly represented by blood urine nitrogen (BUN) and creatinine (Crea) whose removal is critically important in hemodialysis (HD) for kidney disease. Patients …             Effects of halving pesticide use on wheat production ▶     L. Hossard, A. Philibert, M. Bertrand et al.     Pesticides pose serious threats to both human health and the environment. In Europe, farmers are encouraged to reduce their use, and in France a recent environmental policy fixed …             Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin ▶     Xuesong Chen, Yu Li, Qiushi Lin et al.     To study the mechanism of tea polyphenols (TP)-induced apoptosis of breast cancer cells. Proliferation of MCF-7 and SK-BR-3 cells was evaluated by MTT assays. Cellular …             Identification of phenotype deterministic genes using systemic analysis of transcriptional response ▶     Jungsul Lee, Junseong Park, Chulhee Choi     Systemic identification of deterministic genes for different phenotypes is a primary application of high-throughput expression profiles. However, gene expression differences …             Genome wide identification of Fruitless targets suggests a role in upregulating genes important for neural circuit formation ▶     Sonja C. Vernes     The fruitless gene (fru) encodes a set of transcription factors (Fru) that display sexually dimorphic gene expression in the brain of the fruit-fly; Drosophila melanogaster. …             Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models ▶     Karolina Chwalek, Mikhail V. Tsurkan, Uwe Freudenberg et al.     Angiogenesis, the outgrowth of blood vessels, is crucial in development, disease and regeneration. Studying angiogenesis in vitro remains challenging because the capillary …             An evolutionarily conserved protein CHORD regulates scaling of dendritic arbors with body size ▶     Kohei Shimono, Kazuto Fujishima, Takafumi Nomura et al.     Most organs scale proportionally with body size through regulation of individual cell size and/or cell number. Here we addressed how postmitotic and morphologically complex cells …             Hybrid hydrogels containing vertically aligned carbon nanotubes with anisotropic electrical conductivity for muscle myofiber fabrication ▶     Samad Ahadian, Javier Ramón-Azcón, Mehdi Estili et al.     Biological scaffolds with tunable electrical and mechanical properties are of great interest in many different fields, such as regenerative medicine, biorobotics, and biosensing. …             Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment ▶     Zobeida Cruz-Monserrate, Christina L. Roland, Defeng Deng et al.     Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA, accounting for ~40,000 deaths annually. The dismal prognosis for PDAC is largely …             The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures ▶     Romain Pacaud, Emeline Brocard, Lisenn Lalier et al.     Several genetic and epigenetic signatures characterize cancer cells. However, the relationships (causal or consequence link, existence due to a same origin) between these 2 types …             Evidence For Rapid Spatiotemporal Changes in Genetic Structure of an Alien Whitefly During Initial Invasion ▶     Dong Chu, Dong Guo, Yunli Tao et al.     The sweetpotato whitefly Bemisia tabaci Q species is a recent invader and important pest of agricultural crops in China. This research tested the hypothesis that the Q populations …             Comprehensive profiling of the vaginal microbiome in HIV positive women using massive parallel semiconductor sequencing ▶     Adam Ameur, Tracy L. Meiring, Ignas Bunikis et al.     Infections by HIV increase the risk of acquiring secondary viral and bacterial infections and methods are needed to determine the spectrum of co-infections for proper treatment. …             Mussels realize Weierstrassian Lévy walks as composite correlated random walks ▶     Andy M. Reynolds     Composite correlated random walks (CCRW) have been posited as a potential replacement for Lévy walks and it has also been suggested that CCRWs have been mistaken for Lévy walks. …             One-step antibody immobilization-based rapid and highly-sensitive sandwich ELISA procedure for potential in vitro diagnostics ▶     Sandeep Kumar Vashist, E. Marion Schneider, Edmond Lam et al.     An improved enzyme-linked immunosorbent (ELISA) assay using one-step antibody immobilization has been developed for the detection of human fetuin A (HFA), a specific biomarker for …             Boundary layer flow and heat transfer over a nonlinearly permeable stretching/shrinking sheet in a nanofluid ▶     Khairy Zaimi, Anuar Ishak, Ioan Pop     The steady boundary layer flow and heat transfer of a nanofluid past a nonlinearly permeable stretching/shrinking sheet is numerically studied. The governing partial differential …                 Nature Reviews Immunology Focus on Homeostatic immune responses   Read the Focus online: http://bit.ly/OzsLTf           Chemical Sciences ▲ top               Carbon nanocages: A new support material for Pt catalyst with remarkably high durability ▶     Xiao Xia Wang, Zhe Hua Tan, Min Zeng et al.     Low durability is the major challenge hindering the large-scale implementation of proton exchange membrane fuel cell (PEMFC) technology, and corrosion of carbon support materials …             Molecular Structure – Optical Property Relationships for a Series of Non-Centrosymmetric Two-photon Absorbing Push-Pull Triarylamine Molecules ▶     Marcelo G. Vivas, Daniel L. Silva, Jérémy Malinge et al.     This article reports on a comprehensive study of the two-photon absorption (2PA) properties of six novel push-pull octupolar triarylamine compounds as a function of the nature of …             Thin-Layer Polymer Wrapped Enzymes Encapsulated in Hierarchically Mesoporous Silica with High Activity and Enhanced Stability ▶     Fang Zhang, Meitao Wang, Chao Liang et al.     A novel soft-hard cooperative approach was developed to synthesize bioactive mesoporous composite by pre-wrapping Penicillin G amidase with poly(acrylaimde) nanogel skin and …             Bismuthoxyiodide Nanoflakes/Titania Nanotubes Arrayed p-n Heterojunction and Its Application for Photoelectrochemical Bioanalysis ▶     Wei-Wei Zhao, Zhao Liu, Shu Shan et al.     We have developed sensitive detection of cancer biomarker vascular endothelial growth factor (VEGF) using the p-n heterojunction comprised of p-type BiOI nanoflakes (NFs) array …             Inorganic Nanovehicle Targets Tumor in an Orthotopic Breast Cancer Model ▶     Goeun Choi, Oh-Joon Kwon, Yeonji Oh et al.     The clinical efficacy of conventional chemotherapeutic agent, methotrexate (MTX), can be limited by its very short plasma half-life, the drug resistance, and the high dosage …             Hybrid silver nanoparticle/conjugated polyelectrolyte nanocomposites exhibiting controllable metal-enhanced fluorescence ▶     Xiaoyu Wang, Fang He, Xi Zhu et al.     Metal-enhanced fluorescence of conjugated polyelectrolytes (CPs) is realized using a simple, green hybrid Ag nanocomposite film. Ag nanoparticles (Ag NPs) are pre-prepared by …             Resistive Memory for Harsh Electronics: Immunity to Surface Effect and High Corrosion Resistance via Surface Modification ▶     Teng-Han Huang, Po-Kang Yang, Der-Hsien Lien et al.     The tolerance/resistance of the electronic devices to extremely harsh environments is of supreme interest. Surface effects and chemical corrosion adversely affect stability and …                     Physical Sciences ▲ top               All-optical manipulation and probing of the d–f exchange interaction in EuTe ▶     R. R. Subkhangulov, A. B. Henriques, P. H. O. Rappl et al.     We demonstrate that the ultrafast fast dynamics of the d–f exchange interaction, between conduction band electrons and lattice spins in EuTe, can be accessed using an all-optical …             Unusual Compression Behavior of Nanocrystalline CeO2 ▶     Qiming Wang, Duanwei He, Fang Peng et al.     The x-ray diffraction study of 12 nm CeO2 was carried out up to ~40 GPa using an angle dispersive synchrotron-radiation in a diamond-anvil cell with different pressure …             Fracture Characteristics of Monolayer CVD-Graphene ▶     Yun Hwangbo, Choong-Kwang Lee, Sang-Min Kim et al.     We have observed and analyzed the fracture characteristics of the monolayer CVD-graphene using pressure bulge testing setup. The monolayer CVD-graphene has appeared to undergo …             Carbon nanocages: A new support material for Pt catalyst with remarkably high durability ▶     Xiao Xia Wang, Zhe Hua Tan, Min Zeng et al.     Low durability is the major challenge hindering the large-scale implementation of proton exchange membrane fuel cell (PEMFC) technology, and corrosion of carbon support materials …             A multimode electromechanical parametric resonator array ▶     I. Mahboob, M. Mounaix, K. Nishiguchi et al.     Electromechanical resonators have emerged as a versatile platform in which detectors with unprecedented sensitivities and quantum mechanics in a macroscopic context can be …             Investigation on the structure and upconversion fluorescence of Yb3+/Ho3+ co-doped fluorapatite crystals for potential biomedical applications ▶     Xiyu Li, Jingxian Zhu, Zhentao Man et al.     Rare-earth Yb3 and Ho3 co-doped fluorapatite (FA:Yb3/Ho3) crystals were prepared by hydrothermal synthesis, and their structure, upconversion properties, cell proliferation and …             Biased imitation in coupled evolutionary games in interdependent networks ▶     M. D. Santos, S. N. Dorogovtsev, J. F. F. Mendes     We explore the evolutionary dynamics of two games—the Prisoner's Dilemma and the Snowdrift Game—played within distinct networks (layers) of interdependent networks. In these …             Molecular Structure – Optical Property Relationships for a Series of Non-Centrosymmetric Two-photon Absorbing Push-Pull Triarylamine Molecules ▶     Marcelo G. Vivas, Daniel L. Silva, Jérémy Malinge et al.     This article reports on a comprehensive study of the two-photon absorption (2PA) properties of six novel push-pull octupolar triarylamine compounds as a function of the nature of …             Label-Free Characterization of Emerging Human Neuronal Networks ▶     Mustafa Mir, Taewoo Kim, Anirban Majumder et al.     The emergent self-organization of a neuronal network in a developing nervous system is the result of a remarkably orchestrated process involving a multitude of chemical, …             Generation of ultra-sound during tape peeling ▶     Jeremy O. Marston, Paul W. Riker, Sigurdur T. Thoroddsen     We investigate the generation of the screeching sound commonly heard during tape peeling using synchronised high-speed video and audio acquisition. We determine the peak …             Discrete-time quantum walk with feed-forward quantum coin ▶     Yutaka Shikano, Tatsuaki Wada, Junsei Horikawa     Constructing a discrete model like a cellular automaton is a powerful method for understanding various dynamical systems. However, the relationship between the discrete model and …             Thin-Layer Polymer Wrapped Enzymes Encapsulated in Hierarchically Mesoporous Silica with High Activity and Enhanced Stability ▶     Fang Zhang, Meitao Wang, Chao Liang et al.     A novel soft-hard cooperative approach was developed to synthesize bioactive mesoporous composite by pre-wrapping Penicillin G amidase with poly(acrylaimde) nanogel skin and …             Robust longitudinal spin-Seebeck effect in Bi-YIG thin films ▶     Gene Siegel, Megan Campbell Prestgard, Shiang Teng et al.     In recent years, the coupling of magnetic insulators (bismuth-doped yttrium iron garnet, Bi-YIG) with platinum has garnered significant interest in spintronics research due to …             Bismuthoxyiodide Nanoflakes/Titania Nanotubes Arrayed p-n Heterojunction and Its Application for Photoelectrochemical Bioanalysis ▶     Wei-Wei Zhao, Zhao Liu, Shu Shan et al.     We have developed sensitive detection of cancer biomarker vascular endothelial growth factor (VEGF) using the p-n heterojunction comprised of p-type BiOI nanoflakes (NFs) array …             Inorganic Nanovehicle Targets Tumor in an Orthotopic Breast Cancer Model ▶     Goeun Choi, Oh-Joon Kwon, Yeonji Oh et al.     The clinical efficacy of conventional chemotherapeutic agent, methotrexate (MTX), can be limited by its very short plasma half-life, the drug resistance, and the high dosage …             Elementary Process for CVD Graphene on Cu(110): Size-selective Carbon Clusters ▶     Jialin Zhang, Zhunzhun Wang, Tianchao Niu et al.     Revealing the graphene growth mechanism at the atomic-scale is of great importance for achieving high quality graphene. However, the lack of direct experimental observation and …             Innovative strategy with potential to increase hemodialysis efficiency and safety ▶     Hsiao-Chien Chen, Hsiu-Chen Lin, Hsi-Hsien Chen et al.     Uremic toxins are mainly represented by blood urine nitrogen (BUN) and creatinine (Crea) whose removal is critically important in hemodialysis (HD) for kidney disease. Patients …             A General Method for Preparing Anatase TiO2 Treelike-Nanoarrays on Various Metal Wires for Fiber Dye-Sensitized Solar Cells ▶     Liang Chu, Luying Li, Jun Su et al.     Anatase TiO2 tree-like nanoarrays were prepared on various metal wires (Ti, W, Ni, etc.) through one-step facile hydrothermal reaction. The anatase TiO2 tree-like nanoarrays …             Porous Nanocomposites with Integrated Internal Domains: Application to Separation Membranes ▶     Wenle Li, John Y. Walz     Asymmetric membranes with layered structure have made significant achievements due to their balanced properties and multi-functionalities that come from a combination of multiple …             A novel radioguided surgery technique exploiting β− decays ▶     E. Solfaroli Camillocci, G. Baroni, F. Bellini et al.     The background induced by the high penetration power of the radiation is the main limiting factor of the current radio-guided surgery (RGS). To partially mitigate it, a RGS with β…             Average structure and local configuration of excess oxygen in UO2+x ▶     Jianwei Wang, Rodney C. Ewing, Udo Becker     Determination of the local configuration of interacting defects in a crystalline, periodic solid is problematic because defects typically do not have a long-range periodicity. Ur…             Hybrid hydrogels containing vertically aligned carbon nanotubes with anisotropic electrical conductivity for muscle myofiber fabrication ▶     Samad Ahadian, Javier Ramón-Azcón, Mehdi Estili et al.     Biological scaffolds with tunable electrical and mechanical properties are of great interest in many different fields, such as regenerative medicine, biorobotics, and biosensing. …             Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment ▶     Zobeida Cruz-Monserrate, Christina L. Roland, Defeng Deng et al.     Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA, accounting for ~40,000 deaths annually. The dismal prognosis for PDAC is largely …             Resistive Memory for Harsh Electronics: Immunity to Surface Effect and High Corrosion Resistance via Surface Modification ▶     Teng-Han Huang, Po-Kang Yang, Der-Hsien Lien et al.     The tolerance/resistance of the electronic devices to extremely harsh environments is of supreme interest. Surface effects and chemical corrosion adversely affect stability and …             Submerged Liquid Plasma for the Synchronized Reduction and Functionalization of Graphene Oxide ▶     Jaganathan Senthilnathan, Yung-Fang Liu, Kodepelly Sanjeeva Rao et al.     Formation of reduced and functionalized graphene oxide (r-FGO) at ambient temperature and pressure is demonstrated by generating liquid plasma submerged in acetonitrile and …             Atomistic observation of a crack tip approaching coherent twin boundaries ▶     L. Liu, J. Wang, S. K. Gong et al.     Coherent twin boundaries (CTBs) in nano-twinned materials could improve crack resistance. However, the role of the CTBs during crack penetration has never been explored at atomic …             Synthesis, cytotoxicity, and hydroxyapatite formation in 27-Tris-SBF for sol-gel based CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses ▶     Gurbinder Kaur, G. Pickrell, G. Kimsawatde et al.     CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses were prepared via an optimized sol–gel method. The current investigation was focused on producing novel zinc based calcium …             Microyielding of Core-Shell Crystal Dendrites in a Bulk-metallic-glass Matrix Composite ▶     E-Wen Huang, Junwei Qiao, Bartlomiej Winiarski et al.     In-situ synchrotron x-ray experiments have been used to follow the evolution of the diffraction peaks for crystalline dendrites embedded in a bulk metallic glass matrix subjected …             Hybrid silver nanoparticle/conjugated polyelectrolyte nanocomposites exhibiting controllable metal-enhanced fluorescence ▶     Xiaoyu Wang, Fang He, Xi Zhu et al.     Metal-enhanced fluorescence of conjugated polyelectrolytes (CPs) is realized using a simple, green hybrid Ag nanocomposite film. Ag nanoparticles (Ag NPs) are pre-prepared by …             Printable, wide band-gap chalcopyrite thin films for power generating window applications ▶     Sung Hwan Moon, Se Jin Park, Yun Jeong Hwang et al.     Printable, wide band-gap chalcopyrite compound films (CuInGaS2, CIGS) were synthesized on transparent conducting oxide substrates. The wide band-gap and defective nature of the …             Straightforward fabrication of stable white LEDs by embedding of inorganic UV-LEDs into bulk polymerized polymethyl-methacrylate doped with organic dyes ▶     Daniela Di Martino, Luca Beverina, Mauro Sassi et al.     Stable white-emitting down-converted LEDs are straightforwardly prepared by bulk polymerization of an organic dye doped polymethyl-methacrylate (PMMA) shell directly on top of a …             Theoretical modeling of relative humidity on contact electrification of sand particles ▶     XiaoJing Zheng, Rui Zhang, HaoJie Huang     Contact electrification of identical insulating particles has crucial significance for industrial and environmental science, especially in wind-blown granular systems. At the same …             Boundary layer flow and heat transfer over a nonlinearly permeable stretching/shrinking sheet in a nanofluid ▶     Khairy Zaimi, Anuar Ishak, Ioan Pop     The steady boundary layer flow and heat transfer of a nanofluid past a nonlinearly permeable stretching/shrinking sheet is numerically studied. The governing partial differential …               Earth & Environmental Sciences ▲ top               Methane formation and consumption processes in Xiangxi Bay of the Three Gorges Reservoir ▶     Chenghao Wang, Shangbin Xiao, Yingchen Li et al.     Indoor simulation experiment was carried out to evaluate the formation and consumption rates of methane (CH4) in Xiangxi Bay of the Three Gorges Reservoir (TGR), China. The …             Sound management may sequester methane in grazed rangeland ecosystems ▶     Chengjie Wang, Guodong Han, Shiping Wang et al.     Considering their contribution to global warming, the sources and sinks of methane (CH4) should be accounted when undertaking a greenhouse gas inventory for grazed rangeland …             Diel nitrogen fixation pattern of Trichodesmium: the interactive control of light and Ni ▶     Irene B. Rodriguez, Tung-Yuan Ho     Trichodesmium, a nonheterocystous cyanobacterium widely abundant in the surface water of the tropical and subtropical ocean, fixes dinitrogen under high light conditions while …             A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material ▶     Min-Hui Wu, Liang-Ze Wan, Yu-Qing Zhang     A novel sodium N-fatty acyl amino acid (SFAAA) surfactant was synthesized using pupa oil and pupa protein hydrolysates (PPH) from a waste product of the silk industry. The …             Rheological decoupling at the Moho and implication to Venusian tectonics ▶     Shintaro Azuma, Ikuo Katayama, Tomoeki Nakakuki     Plate tectonics is largely responsible for material and heat circulation in Earth, but for unknown reasons it does not exist on Venus. The strength of planetary materials is a key …             Madagascar corals track sea surface temperature variability in the Agulhas Current core region over the past 334 years ▶     J. Zinke, B. R. Loveday, C. J. C. Reason et al.     The Agulhas Current (AC) is the strongest western boundary current in the Southern Hemisphere and is key for weather and climate patterns, both regionally and globally. Its heat …             Theoretical modeling of relative humidity on contact electrification of sand particles ▶     XiaoJing Zheng, Rui Zhang, HaoJie Huang     Contact electrification of identical insulating particles has crucial significance for industrial and environmental science, especially in wind-blown granular systems. At the same …               Health Sciences ▲ top               HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors ▶     Xun Liu, Ankit Shah, Mohitkumar R. Gangwani et al.     The prevalence of HIV-associated neurocognitive disorders (HAND) remains high in patients infected with HIV-1. The production of pro-inflammatory cytokines by astrocytes/microglia …             Innovative strategy with potential to increase hemodialysis efficiency and safety ▶     Hsiao-Chien Chen, Hsiu-Chen Lin, Hsi-Hsien Chen et al.     Uremic toxins are mainly represented by blood urine nitrogen (BUN) and creatinine (Crea) whose removal is critically important in hemodialysis (HD) for kidney disease. Patients …             Novel Multiplex MethyLight Protocol for Detection of DNA Methylation in Patient Tissues and Bodily Fluids ▶     Ekaterina Olkhov-Mitsel, Darko Zdravic, Ken Kron et al.     Aberrant DNA methylation is a hallmark of cancer and is an important potential biomarker. Particularly, combined analysis of a panel of hypermethylated genes shows the most …             Information content and analysis methods for Multi-Modal High-Throughput Biomedical Data ▶     Bisakha Ray, Mikael Henaff, Sisi Ma et al.     The spectrum of modern molecular high-throughput assaying includes diverse technologies such as microarray gene expression, miRNA expression, proteomics, DNA methylation, among …             Involvement of Autophagy in Antitumor Activity of Folate-appended Methyl-β-cyclodextrin ▶     Risako Onodera, Keiichi Motoyama, Nao Tanaka et al.     Autophagy, the major lysosomal pathway for recycling intracellular components including organelles, is emerging as a key process regulating tumorigenesis and cancer therapy. Most …             A novel radioguided surgery technique exploiting β− decays ▶     E. Solfaroli Camillocci, G. Baroni, F. Bellini et al.     The background induced by the high penetration power of the radiation is the main limiting factor of the current radio-guided surgery (RGS). To partially mitigate it, a RGS with β…             One-step antibody immobilization-based rapid and highly-sensitive sandwich ELISA procedure for potential in vitro diagnostics ▶     Sandeep Kumar Vashist, E. Marion Schneider, Edmond Lam et al.     An improved enzyme-linked immunosorbent (ELISA) assay using one-step antibody immobilization has been developed for the detection of human fetuin A (HFA), a specific biomarker for …                 • Careers & Jobs           naturejobs.com Science jobs of the week       Postdoctoral Fellowship     The National Heart, Lung, and Blood Institute (NHLBI)             Research Associate     King's College London            Postdoctoral Fellow     Centre for Integrative Biology (CIBio) - University of Trento            PhD Studentship     The Pirbright Institute            Postdoctoral Scholar     University of Chicago            PhD Student positions     Goethe University Frankfurt a.M., Institute for Biochemistry II            Research Technician     University of Edinburgh            Postdoctoral Research Associate     Princeton University            Research Fellow     The University of Warwick            PhD Fellowship     Albert Ludwig University Medical Center Freiburg          No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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