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2014/05/27

Scientific Reports Biology Table of Contents e-alert: 27 May 2014

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  27 May 2014   
 
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Welcome to your Table of Contents e-alert for Scientific Reports

 
 
   
 
 
 
Biological Sciences
 
 
 
 
 
 
 

What triggers the rising of an intraspecific biodiversity hotspot? Hints from the agile frog

 
 

Daniele Canestrelli, Roberta Bisconti, Florinda Sacco et al.

 
 

Hotspots of genetic diversity are regions of utmost importance for species survival and conservation, and their intimate link with the geographic location of glacial refugia has …

 
 
 
 
 
 

Nanoliter-Scale Protein Crystallization and Screening with a Microfluidic Droplet Robot

 
 

Ying Zhu, Li-Na Zhu, Rui Guo et al.

 
 

Large-scale screening of hundreds or even thousands of crystallization conditions while with low sample consumption is in urgent need, in current structural biology research. Here …

 
 
 
 
 
 

Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity

 
 

Zhiyao Fu, Feven Berhane, Alemu Fite et al.

 
 

Lipasin (also known as C19ORF80, RIFL, ANGPTL8 and betatrophin) is a newly discovered circulating factor that regulates lipid metabolism and promotes pancreatic β-cell …

 
 
 
 
 
 

Regulation of secondary cell wall biosynthesis by poplar R2R3 MYB transcription factor PtrMYB152 in Arabidopsis

 
 

Shucai Wang, Eryang Li, Ilga Porth et al.

 
 

Poplar has 192 annotated R2R3 MYB genes, of which only three have been shown to play a role in the regulation of secondary cell wall formation. Here we report the characterization …

 
 
 
 
 
 

Involvement of the Wbp pathway in the biosynthesis of Porphyromonas gingivalis lipopolysaccharide with anionic polysaccharide

 
 

Mikio Shoji, Keiko Sato, Hideharu Yukitake et al.

 
 

The periodontal pathogen Porphyromonas gingivalis has two different lipopolysaccharide (LPS) molecules, O-LPS and A-LPS. We have recently shown that P. gingivalis strain HG66 …

 
 
 
 
 
 

Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus

 
 

Yohei Matsubara, Tomoki Chiba, Kenichi Kashimada et al.

 
 

X-linked severe combined immunodeficiency (SCID-X1) caused by mutations in interleukin 2 receptor gamma (IL2RG) gene threatens the survival of affected boys during the first year …

 
 
 
 
 
 

Effects of externally supplied protein on root morphology and biomass allocation in Arabidopsis

 
 

Thierry G. A. Lonhienne, Yuri Trusov, Anthony Young et al.

 
 

Growth, morphogenesis and function of roots are influenced by the concentration and form of nutrients present in soils, including low molecular mass inorganic N (IN, ammonium, …

 
 
 
 
 
 

PCR amplification of repetitive DNA: a limitation to genome editing technologies and many other applications

 
 

Carl Maximilian Hommelsheim, Lamprinos Frantzeskakis, Mengmeng Huang et al.

 
 

Designer transcription-activator like effectors (TALEs) is a promising technology and made it possible to edit genomes with higher specificity. Such specific engineering and gene …

 
 
 
 
 
 

PHF8 and REST/NRSF co-occupy gene promoters to regulate proximal gene expression

 
 

Juan Wang, Xueqiu Lin, Su Wang et al.

 
 

Chromatin regulators play an important role in the development of human diseases. In this study, we focused on Plant Homeo Domain Finger protein 8 (PHF8), a chromatin regulator …

 
 
 
 
 
 

Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis

 
 

Takako Iitsuka, Kaoru Mita, Akiko Hozumi et al.

 
 

Maternal mRNAs play crucial roles during early embryogenesis of ascidians, but their functions are largely unknown. In this study, we developed a new method to specifically …

 
 
 
 
 
 

Strong non-classical induction forces in ion-surface interactions: General origin of Hofmeister effects

 
 

Xinmin Liu, Hang Li, Rui Li et al.

 
 

Hofmeister effects continue to defy all-encompassing theories, and their origin is still a matter of debate. We observed strong Hofmeister effects in Ca2/Na exchange on a …

 
 
 
 
 
 

Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations

 
 

Graham K. Sheridan, Kumlesh K. Dev

 
 

Fingolimod (FTY720) is an oral therapy for relapsing remitting multiple sclerosis (MS) and targets sphingosine 1-phosphate receptors (S1PRs). FTY720 also rescues animals from …

 
 
 
 
 
 

Peripheral blood miRNAs as a biomarker for chronic cardiovascular diseases

 
 

Yong Jiang, Hui-yan Wang, Hong-mei Cao et al.

 
 

Vascular diseases are the most prevalent diseases worldwide. This study intended to analyze peripheral blood miRNA levels and their correlation with NT-pro-BNP and cTN-I in …

 
 
 
 
 
 

No evident dose-response relationship between cellular ROS level and its cytotoxicity – a paradoxical issue in ROS-based cancer therapy

 
 

Chunpeng Zhu, Wei Hu, Hao Wu et al.

 
 

Targeting cancer via ROS-based mechanism has been proposed as a radical therapeutic approach. Cancer cells exhibit higher endogenous oxidative stress than normal cells and …

 
 
 
 
 
 

Characterizing the effect of population heterogeneity on evolutionary dynamics on complex networks

 
 

Shaolin Tan, Jinhu Lü

 
 

Recently, the impact of network structure on evolutionary dynamics has been at the center of attention when studying the evolutionary process of structured populations. This paper …

 
 
 
 
 
 

Impaired Frontal-Basal Ganglia Connectivity in Adolescents with Internet Addiction

 
 

Baojuan Li, Karl J. Friston, Jian Liu et al.

 
 

Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study …

 
 
 
 
 
 

Fabricating nanopores with diameters of sub-1 nm to 3 nm using multilevel pulse-voltage injection

 
 

Itaru Yanagi, Rena Akahori, Toshiyuki Hatano et al.

 
 

To date, solid-state nanopores have been fabricated primarily through a focused-electronic beam via TEM. For mass production, however, a TEM beam is not suitable and an …

 
 
 
 
 
 

Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

 
 

Jichuang Wang, Zhou Jiang, Liping Xiang et al.

 
 

Ursolic acid (UA) is a naturally bioactive product that exhibits potential anticancer effects. The relatively safe and effective molecule intrigued us to explore a way to further …

 
 
 
 
 
 

Expression of Arabidopsis MYB transcription factor, AtMYB111, in tobacco requires light to modulate flavonol content

 
 

Ashutosh Pandey, Prashant Misra, Sweta Bhambhani et al.

 
 

Flavonoids, due to their pharmacological attributes, have recently become target molecules for metabolic engineering in commonly consumed food crops. Strategies including …

 
 
 
 
 
 

Promoting Interspecies Electron Transfer with Biochar

 
 

Shanshan Chen, Amelia-Elena Rotaru, Pravin Malla Shrestha et al.

 
 

Biochar, a charcoal-like product of the incomplete combustion of organic materials, is an increasingly popular soil amendment designed to improve soil fertility. We investigated …

 
 
 
 
 
 

Cholesterol level affects surface charge of lipid membranes in saline solution

 
 

Aniket Magarkar, Vivek Dhawan, Paraskevi Kallinteri et al.

 
 

Cholesterol is an important component of all biological membranes as well as drug delivery liposomes. We show here that increasing the level of cholesterol in a phospholipid …

 
 
 
 
 
 

Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization

 
 

Yan-Qing Guan, Zhe Zheng, Zheng Huang et al.

 
 

Nanomagnetic materials offer exciting avenues for advancing cancer therapies. Most researches have focused on efficient delivery of drugs in the body by incorporating various drug …

 
 
 
 
 
 

Mapping Brain Injury with Symmetrical-channels' EEG Signal Analysis – A Pilot Study

 
 

LI Yi, LIU Xiao-ping, LING Xian-hong et al.

 
 

A technique for detecting brain injury at the bedside has great clinical value, but conventional imaging techniques (such as computed tomography [CT] and magnetic resonance …

 
 
 
 
 
 

Revealing Real-Time Emotional Responses: a Personalized Assessment based on Heartbeat Dynamics

 
 

Gaetano Valenza, Luca Citi, Antonio Lanatá et al.

 
 

Emotion recognition through computational modeling and analysis of physiological signals has been widely investigated in the last decade. Most of the proposed emotion recognition …

 
 
 
 
 
 

PEG Molecular Net-Cloth Grafted on Polymeric Substrates and Its Bio-Merits

 
 

Changwen Zhao, Zhifeng Lin, Huabing Yin et al.

 
 

Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for the first time, we report a non-swelling …

 
 
 
 
 
 
   
 
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