Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 96 Issue 1

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TABLE OF CONTENTS Volume 96, Issue 1 (July 2014) In this issue In This Issue Editorial News & Views Perspectives Clinical Trial State of the Art Reviews Research Also new AOP Sign up for CPT: Pharmacometrics & Systems Pharmacology e-alerts Sign up for e-alerts Recommend to your library Web feed Subscribe In This Issue Top In This Issue Clin Pharmacol Ther 2014 96: 1; 10.1038/clpt.2014.104 Full Text Editorial Top Reducing Elevated Plasma LDL Cholesterol: The Central Role of the LDL Receptor J Vincent Clin Pharmacol Ther 2014 96: 3-7; 10.1038/clpt.2014.95 Abstract | Full Text News & Views Top HIGHLIGHTS Clin Pharmacol Ther 2014 96: 8-9; 10.1038/clpt.2014.103 Full Text ASCPT NEWS Clin Pharmacol Ther 2014 96: 10-13; 10.1038/clpt.2014.91 Full Text Perspectives Top POINT/COUNTERPOINT Patients Benefit From Genetics-Guided Coumarin Anticoagulant Therapy A H Maitland-van der Zee, A K Daly, F Kamali, V G Manolopoulous, T I Verhoef, M Wadelius, A de Boer and M Pirmohamed ; on behalf of the EU-PACT Study Group Clin Pharmacol Ther 2014 96: 15-17; 10.1038/clpt.2014.44 Abstract | Full Text New Oral Anticoagulants vs. Warfarin Treatment: No Need for Pharmacogenomics? W L Baker and K W Chamberlin Clin Pharmacol Ther 2014 96: 17-19; 10.1038/clpt.2014.48 Abstract | Full Text COMMENTARIES Measurement of Low-Density Lipoprotein Cholesterol in Assessment and Management of Cardiovascular Disease Risk I Jialal and A T Remaley Clin Pharmacol Ther 2014 96: 20-22; 10.1038/clpt.2014.69 Abstract | Full Text Warfarin Pharmacogenetics: To Genotype or Not to Genotype, That Is the Question L H Cavallari and E A Nutescu Clin Pharmacol Ther 2014 96: 22-24; 10.1038/clpt.2014.78 Abstract | Full Text LETTERS TO THE EDITOR Clinically Actionable Genotypes Among Brazilians G Suarez-Kurtz Clin Pharmacol Ther 2014 96: 25-26; advance online publication, March 5, 2014; 10.1038/clpt.2014.56 Full Text Response to “Clinically Actionable Genotypes Among Brazilians” S L Van Driest and D M Roden Clin Pharmacol Ther 2014 96: 26; advance online publication, March 28, 2014; 10.1038/clpt.2014.71 Full Text Clinical Trial Top Sorafenib Dose Escalation Is Not Uniformly Associated With Blood Pressure Elevations in Normotensive Patients With Advanced Malignancies S Karovic, Y Wen, T G Karrison, G L Bakris, M R Levine, L K House, K Wu, V Thomeas, M A Rudek, J J Wright, E E W Cohen, G F Fleming, M J Ratain and M L Maitland Clin Pharmacol Ther 2014 96: 27-35; advance online publication, March 17, 2014; 10.1038/clpt.2014.63 Abstract | Full Text State of the Art Top Pharmacogenomics, Lipid Disorders, and Treatment Options S E Gryn and R A Hegele Clin Pharmacol Ther 2014 96: 36-47; advance online publication, April 10, 2014; 10.1038/clpt.2014.82 Abstract | Full Text High-Density Lipoproteins in the Prevention of Cardiovascular Disease: Changing the Paradigm S Tuteja and D J Rader Clin Pharmacol Ther 2014 96: 48-56; advance online publication, April 8, 2014; 10.1038/clpt.2014.79 Abstract | Full Text An Overview of the New Frontiers in the Treatment of Atherogenic Dyslipidemias F H Rached, M J Chapman and A Kontush Clin Pharmacol Ther 2014 96: 57-63; advance online publication, April 11, 2014; 10.1038/clpt.2014.85 Abstract | Full Text Reviews Top The Ebbs and Flows in the Development of Cholesterol-Lowering Drugs: Prospects for the Future R Hajhosseiny, I Sabir, K Khavandi and A S Wierzbicki Clin Pharmacol Ther 2014 96: 64-73; advance online publication, April 3, 2014; 10.1038/clpt.2014.76 Abstract | Full Text A Current Approach to Statin Intolerance R Tompkins, A Schwartzbard, E Gianos, E Fisher and H Weintraub Clin Pharmacol Ther 2014 96: 74-80; advance online publication, April 11, 2014; 10.1038/clpt.2014.84 Abstract | Full Text Research Top ARTICLES Association Analysis of Genetic Polymorphisms in Genes Related to Sunitinib Pharmacokinetics, Specifically Clearance of Sunitinib and SU12662 M H M Diekstra, H J Klümpen, M P J K Lolkema, H Yu, J S L Kloth, H Gelderblom, R H N van Schaik, H Gurney, J J Swen, A D R Huitema, N Steeghs and R H J Mathijssen Clin Pharmacol Ther 2014 96: 81-89; advance online publication, February 24, 2014; 10.1038/clpt.2014.47 Abstract | Full Text Identification of the Effect of Multiple Polymorphisms on the Pharmacokinetics of Simvastatin and Simvastatin Acid Using a Population-Modeling Approach N Tsamandouras, G Dickinson, Y Guo, S Hall, A Rostami-Hodjegan, A Galetin and L Aarons Clin Pharmacol Ther 2014 96: 90-100; advance online publication, March 5, 2014; 10.1038/clpt.2014.55 Abstract | Full Text Prediction of Clinical Irrelevance of PK Differences in Atorvastatin Using PK/PD Models Derived From Literature-Based Meta-Analyses OPEN R Vargo, A Adewale, M O Behm, J Mandema and T Kerbusch Clin Pharmacol Ther 2014 96: 101-109; advance online publication, March 28, 2014; 10.1038/clpt.2014.66 Abstract | Full Text Antiretroviral Therapy–Induced Mitochondrial Toxicity: Potential Mechanisms Beyond Polymerase-γ Inhibition S Selvaraj, M Ghebremichael, M Li, Y Foli, A Langs-Barlow, A Ogbuagu, L Barakat, E Tubridy, R Edifor, W Lam, Y-C Cheng and E Paintsil Clin Pharmacol Ther 2014 96: 110-120; advance online publication, March 17, 2014; 10.1038/clpt.2014.64 Abstract | Full Text Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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