Scientific Reports Biology Table of Contents e-alert: 17 June 2014

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17 June 2014      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports               Biological Sciences               A computational model unifies apparently contradictory findings concerning phantom pain ▶     Kim J. Boström, Marc H. E. de Lussanet, Thomas Weiss et al.     Amputation often leads to painful phantom sensations, whose pathogenesis is still unclear. Supported by experimental findings, an explanatory model has been proposed that …             Extending the viability of acute brain slices ▶     Yossi Buskila, Paul P. Breen, Jonathan Tapson et al.     The lifespan of an acute brain slice is approximately 6–12 hours, limiting potential experimentation time. We have designed a new recovery incubation system capable of extending …             Is ostension any more than attention? ▶     Joanna Szufnarowska, Katharina J. Rohlfing, Christine Fawcett et al.     According to natural pedagogy theory, infants are sensitive to particular ostensive cues that communicate to them that they are being addressed and that they can expect to learn …             Behavioural screening of zebrafish using neuroactive traditional Chinese medicine prescriptions and biological targets ▶     Ya-Nan Wang, Yuan-Yuan Hou, Ming-Zhu Sun et al.     The mechanism of the therapeutic action of antidepressants remains uncertain in traditional Chinese medicine (TCM). In this study, we selected 7 classical TCM prescriptions and …             Computational Analysis of Enhanced Magnetic Bioseparation in Microfluidic Systems with Flow-Invasive Magnetic Elements ▶     S. A. Khashan, A. Alazzam, E. P. Furlani     A microfluidic design is proposed for realizing greatly enhanced separation of magnetically-labeled bioparticles using integrated soft-magnetic elements. The elements are fixed …             MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo ▶     Takahiro Horie, Tomohiro Nishino, Osamu Baba et al.     MicroRNAs (miRs) are small non-protein-coding RNAs that bind to specific mRNAs and inhibit translation or promote mRNA degradation. Recent reports, including ours, indicated that …             CORRIGENDUM: Adaptor protein complexes-1 and 3 are involved at distinct stages of flavivirus life-cycle ▶     Tanvi Agrawal, Peter Schu, Guruprasad R. Medigeshi                 A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans ▶     Pénélope A. Andreux, Laurent Mouchiroud, Xu Wang et al.     Mitochondria are semi-autonomous organelles regulated by a complex network of proteins that are vital for many cellular functions. Because mitochondrial modulators can impact many …             Gibberellin deficiency pleiotropically induces culm bending in sorghum: an insight into sorghum semi-dwarf breeding ▶     Reynante L. Ordonio, Yusuke Ito, Asako Hatakeyama et al.     Regulation of symmetrical cell growth in the culm is important for proper culm development. So far, the involvement of gibberellin (GA) in this process has not yet been …             Synchrony and motor mimicking in chimpanzee observational learning ▶     Delia Fuhrmann, Andrea Ravignani, Sarah Marshall-Pescini et al.     Cumulative tool-based culture underwrote our species' evolutionary success, and tool-based nut-cracking is one of the strongest candidates for cultural transmission in our closest …             Omics-based interpretation of synergism in a soil-derived cellulose-degrading microbial community ▶     Yizhuang Zhou, Phillip B. Pope, Shaochun Li et al.     Reaching a comprehensive understanding of how nature solves the problem of degrading recalcitrant biomass may eventually allow development of more efficient biorefining processes. …             Tug-of-war of microtubule filaments at the boundary of a kinesin- and dynein-patterned surface ▶     Junya Ikuta, Nagendra K. Kamisetty, Hirofumi Shintaku et al.     Intracellular cargo is transported by multiple motor proteins. Because of the force balance of motors with mixed polarities, cargo moves bidirectionally to achieve biological …             DJ-1 contributes to adipogenesis and obesity-induced inflammation ▶     Jung-Min Kim, Hyun-Jun Jang, Soo Youn Choi et al.     Adipose tissue functions as an endocrine organ, and the development of systemic inflammation in adipose tissue is closely associated with metabolic diseases, such as obesity and …             A reversal of fortunes: climate change ‘winners’ and ‘losers’ in Antarctic Peninsula penguins ▶     Gemma V. Clucas, Michael J. Dunn, Gareth Dyke et al.     Climate change is a major threat to global biodiversity. Antarctic ecosystems are no exception. Investigating past species responses to climatic events can distinguish natural …             A pollen-specific calmodulin-binding protein, NPG1, interacts with putative pectate lyases ▶     Sung-Bong Shin, Maxim Golovkin, Anireddy S. N. Reddy     Previous genetic studies have revealed that a pollen-specific calmodulin-binding protein, No Pollen Germination 1 (NPG1), is required for pollen germination. However, its mode of …             Molecular Analysis of β-Lactamase Genes to Understand their Differential Expression in Strains of Yersinia enterocolitica Biotype 1A ▶     Neelja Singhal, Manish Kumar, Jugsharan Singh Virdi     Beta-lactams are used as major therapeutic agents against a number of infectious agents. Due to widespread use of β-lactams, β-lactamases have evolved at a rapid pace leading to …             Tongue adhesion in the horned frog Ceratophrys sp. ▶     Thomas Kleinteich, Stanislav N. Gorb     Frogs are well-known to capture elusive prey with their protrusible and adhesive tongues. However, the adhesive performance of frog tongues and the mechanism of the contact …             Fully automated high-throughput chromatin immunoprecipitation for ChIP-seq: Identifying ChIP-quality p300 monoclonal antibodies ▶     William C. Gasper, Georgi K. Marinov, Florencia Pauli-Behn et al.     Chromatin immunoprecipitation coupled with DNA sequencing (ChIP-seq) is the major contemporary method for mapping in vivo protein-DNA interactions in the genome. It identifies …             Richness and Diversity in Dust Stormborne Biomes at the Southeast Mediterranean ▶     Itzhak Katra, Luba Arotsker, Helena Krasnov et al.     Dust storms include particulate matter that is transported over land and sea with biota that could impact downwind ecosystems. In addition to the physico-chemical compositions, …             Spatial Elucidation of Spinal Cord Lipid- and Metabolite- Regulations in Amyotrophic Lateral Sclerosis ▶     Jörg Hanrieder, Andrew G. Ewing     Amyotrophic lateral sclerosis (ALS) is a devastating, rapidly progressing disease of the central nervous system that is characterized by motor neuron degeneration in the brain …             Stable acetate production in extreme-thermophilic (70°C) mixed culture fermentation by selective enrichment of hydrogenotrophic methanogens ▶     Fang Zhang, Yan Zhang, Jing Ding et al.     The control of metabolite production is difficult in mixed culture fermentation. This is particularly related to hydrogen inhibition. In this work, hydrogenotrophic methanogens …             The largest Silurian vertebrate and its palaeoecological implications ▶     Brian Choo, Min Zhu, Wenjin Zhao et al.     An apparent absence of Silurian fishes more than half-a-metre in length has been viewed as evidence that gnathostomes were restricted in size and diversity prior to the Devonian. …             Preliminary Study on Retinal Vascular and Oxygen-related Changes after Long-term Silicone Oil and Foldable Capsular Vitreous Body Tamponade ▶     Wei Yang, Yongguang Yuan, Yao Zong et al.     Silicone oil has been the only long-term vitreous substitute used in the treatment of retinal detachment since 1962 by Cibis. Nevertheless, its effects on retinal vascular …             Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis ▶     Lotte Hiddingh, Rajiv S. Raktoe, Judith Jeuken et al.     Drug resistance is a major issue in the treatment of glioblastoma. Almost all glioblastomas are intrinsically resistant to chemotherapeutic temozolomide (TMZ) or develop …             Parathyroid hormone and parathyroid hormone type-1 receptor accelerate myocyte differentiation ▶     Shigemi Kimura, Kowasi Yoshioka     The ZHTc6-MyoD embryonic stem cell line expresses the myogenic transcriptional factor MyoD under the control of a tetracycline-inducible promoter. Following induction, most of the …             Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders ▶     Ryoichi Fujiwara, Saya Takenaka, Mitsuhiro Hashimoto et al.     Solute carrier (SLC) transporters play important roles in absorption and disposition of drugs in cells; however, the expression pattern of human SLC transporters in the skin has …             Bemisia tabaci Q carrying tomato yellow leaf curl virus strongly suppresses host plant defenses ▶     Xiaobin Shi, Huipeng Pan, Hongyi Zhang et al.     The concurrence of tomato yellow leaf curl virus (TYLCV) with the spread of its vector Bemisia tabaci Q rather than B in China suggests a more mutualistic relationship between …             Separating the wheat from the chaff – a strategy to utilize plant genetic resources from ex situ genebanks ▶     Jens Keilwagen, Benjamin Kilian, Hakan Özkan et al.     The need for higher yielding and better-adapted crop plants for feeding the world's rapidly growing population has raised the question of how to systematically utilize large …             Cutting-Edge Analysis of Extracellular Microparticles using ImageStreamX Imaging Flow Cytometry ▶     Sarah E. Headland, Hefin R. Jones, Adelina S. V. D'Sa et al.     Interest in extracellular vesicle biology has exploded in the past decade, since these microstructures seem endowed with multiple roles, from blood coagulation to inter-cellular …             The maximum specific hydrogen-producing activity of anaerobic mixed cultures: definition and determination ▶     Yang Mu, Hou-Yun Yang, Ya-Zhou Wang et al.     Fermentative hydrogen production from wastes has many advantages compared to various chemical methods. Methodology for characterizing the hydrogen-producing activity of anaerobic …             Quantity and accessibility for specific targeting of receptors in tumours ▶     Sajid Hussain, Maria Rodriguez-Fernandez, Gary B. Braun et al.     Synaphic (ligand-directed) targeting of drugs is an important potential new approach to drug delivery, particularly in oncology. Considerable success with this approach has been …             A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases ▶     Ningning Liu, Chunjiao Liu, Xiaofen Li et al.     The successful development of bortezomib-based therapy for treatment of multiple myeloma has established proteasome inhibition as an effective therapeutic strategy, and both 20S …                     • Careers & Jobs           naturejobs.com Science jobs of the week       Group leader positions in Development & Stem Cells     IGBMC (Institute of Genetics & Molecular & Cellular Biology)/ CERBM GIE            Postdoctoral Research Scientist     Wellcome Trust Centre for Human Genetics            Wissenschaftliche / r Mitarbeiter / in / Postdoctoral research fellow     Robert Koch - Institut            Professor     Helmholtz Institute Erlangen-Nürnberg            Scientific employees (Postdoctoral Positions)     Philipps-University            Clinical Research Fellow in Surgery     University of Glasgow            Volunteer Studies and Clinical Services / Research Manager     Medical Research Council - Human Nutrition Research            Volunteer Studies and Clinical Services / Research Manager     Medical Research Council - Human Nutrition Research            Research Associate in Statistical Population Genetics     University College London (UCL)            Research Fellow, Synthetic Biology (Biological Sciences)     University of Essex          No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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