The EMBO Journal Table of Contents for 2 June 2014; Vol. 33, No. 11

2 June 2014 | Volume 33, Number 11 Submit Table of Contents Have you seen? Review Articles Corrigendum Volume 33, Number 11 Have you seen? The uncommon roles of common gene regulatory factors in the genomes of differentiating cells The integration of various ‘systems‐level’ analyses reveals functional, rather than opportunistic, promoter binding of a common set of hematopoietic transcription factors to govern tissue‐specific gene expression. Eric H Davidson Published online 30.04.2014 The ER under rapid fire Combining the iPSC technology with genome‐editing/genome‐sequencing and cell‐biological tools offers intriguing novel insights into the molecular aberrations that cause fatal motoneuron death in ALS patients. Benjamin M Schwenk and Dieter Edbauer Published online 30.04.2014 Review Playing TETris with DNA modifications While new functions of Ten Eleven Translocation (TET) enzymes are rapidly emerging, this review aims to summarize crucial aspects of their enzymatic activities, roles in reprogramming and disease with a particular emphasis on neuronal disorders. Benjamin Delatte, Rachel Deplus, and François Fuks Published online 13.05.2014 Articles Key regulators control distinct transcriptional programmes in blood progenitor and mast cells Comparative profiling of ten key haematopoietic transcription factors in blood progenitors versus mast cells demonstrates tissue‐specific binding profiles that functionally determine cellular identify. Fernando J Calero‐Nieto, Felicia S Ng, Nicola K Wilson, Rebecca Hannah, Victoria Moignard, Ana I Leal‐Cervantes, Isabel Jimenez‐Madrid, Evangelia Diamanti, Lorenz Wernisch, and Berthold Göttgens Published online 23.04.2014 ICK is essential for cell type‐specific ciliogenesis and the regulation of ciliary transport Intestinal cell kinase (ICK) phosphorylates the kinesin‐2 subunit Kif3a to regulate intraflagellar transport and therefore ciliary morphogenesis. ICK deficiency leads to cell type‐specific loss of cilia and defective Sonic Hedgehog signaling during central nervous system development. Taro Chaya, Yoshihiro Omori, Ryusuke Kuwahara, and Takahisa Furukawa Published online 05.05.2014 STAG3‐mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis A hypomorphic allele of the meiosis‐specific cohesin subunit STAG3/SA3 reveals its essential functions in meiotic chromosome organization and gametogenesis in mice. Tomoyuki Fukuda, Nanaho Fukuda, Ana Agostinho, Abrahan Hernández‐Hernández, Anna Kouznetsova, and Christer Höög Published online 05.05.2014 Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion Mice lacking STAG3/SA3, the least understood meiosis‐specific cohesin subunit, are found to exhibit the strongest phenotype of any meiotic cohesin protein deficiency analyzed so far. Tristan Winters, Francois McNicoll, and Rolf Jessberger Published online 05.05.2014 MiR‐135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF‐β/BMP signaling A genome‐wide association study on the neural inducer Pax6 identifies miR‐135b as a novel Pax6 target that promotes neuroectoderm induction by antagonizing BMP and Activin/Nodal signals. Akshay Bhinge, Jeremie Poschmann, Seema C Namboori, Xianfeng Tian, Sharon Jia Hui Loh, Anna Traczyk, Shyam Prabhakar, and Lawrence W Stanton Published online 06.05.2014 Corrigendum Origin plasticity during budding yeast DNA replication in vitro Julien Gros, Sujan Devbhandari, and Dirk Remus Published online 02.06.2014   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2014 by the European Molecular Biology Organisation.