Nature Reviews Cardiology - Table of Contents alert Volume 11 Issue 8

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TABLE OF CONTENTS
August 2014 Volume 11 Number 8
Impact Factor 10.400 *	In this issue Research Highlights News and Views Correspondence Reviews Also this month  Featured article: Strategies to improve cardiac resynchronization therapy Kevin Vernooy, Caroline J. M. van Deursen, Marc Strik & Frits W. Prinzen
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RESEARCH HIGHLIGHTS Top Risk factors: Mechanistic insights into the cardiovascular benefits of a Mediterranean diet Published online: 01 July 2014 p433 | doi:10.1038/nrcardio.2014.92 PDF Heart failure: Processed meat and heart failure Published online: 01 July 2014 p434 | doi:10.1038/nrcardio.2014.93 PDF Risk factors: Effects of alcohol consumption on MI risk—evidence from INTERHEART Published online: 01 July 2014 p434 | doi:10.1038/nrcardio.2014.94 PDF Hypertension: Benefits of combined therapy Published online: 17 June 2014 p435 | doi:10.1038/nrcardio.2014.86 PDF Prevention: High-potency statins associated with increased diabetes risk Published online: 17 June 2014 p435 | doi:10.1038/nrcardio.2014.87 PDF Prevention: Smoke-free legislation and acute MI Published online: 24 June 2014 p435 | doi:10.1038/nrcardio.2014.90 PDF Atrial fibrillation: FGF-23 associated with incident AF—a link with CKD? Published online: 01 July 2014 p436 | doi:10.1038/nrcardio.2014.95 PDF Acute coronary syndromes: Promising data for losmapimod in NSTEMI Published online: 01 July 2014 p436 | doi:10.1038/nrcardio.2014.96 PDF Cardiology JOBS of the week Postdoctoral Research Scientist for Cardio-Vascular Responses, Cardiovascular and Metabolic Drug Discovery Unit Takeda Pharmaceutical Company Limited PhD studentship positions at the Dept. of Pharmacology, Max Planck Institute for Heart and Lung Research Max Planck Institute for Heart and Lung Research Research Assistant / Associate - Developmental Programming of Heart Disease University of Cambridge More Science jobs from Cardiology EVENT 2014 Cardiometabolic Health Congress 22.10.14 Boston, USA More science events from
NEWS AND VIEWS		Top
Interventional cardiology: Transformation to transradial—safe and effective Ian C. Gilchrist Published online: 03 June 2014 p437 | doi:10.1038/nrcardio.2014.79 Analysis of cardiovascular registry data suggests that cardiologists who practice femoral cardiac catheterization can convert to safer transradial approaches with a learning experience of 30-50 procedures. This conversion is associated with no loss of procedural success and no increase in serious adverse outcomes. Full Text | PDF
Prevention: Aspirin in primary prevention needs individual judgements Charles H. Hennekens & David L. DeMets Published online: 24 June 2014 p438 | doi:10.1038/nrcardio.2014.88 In May 2014, the FDA astutely stated that any decision to use aspirin should be an individual clinical judgement by health-care providers. Almost simultaneously, the MESA investigators formulated, but did not test, a hypothesis that coronary artery calcification scoring might aid health-care providers in making this judgement. Full Text | PDF
Acute coronary syndromes: Treatment for low-risk patients with STEMI—challenges remain Tariq Ahmad & Matthew T. Roe Published online: 24 June 2014 p440 | doi:10.1038/nrcardio.2014.89 Mineralocorticoid-receptor antagonists (MRAs) have been shown to reduce adverse cardiovascular outcomes in high-risk patients with ST-segment elevation myocardial infarction (STEMI). Preliminary data suggest that MRAs might improve natriuretic-peptide profiles in patients with STEMI who do not have heart failure, but their clinical efficacy in this patient population requires further study. Full Text | PDF
CORRESPONDENCE		Top
CORP-2 trial and the role of colchicine in nonidiopathic pericarditis Lovely Chhabra, Kirandeep Dua & David H. Spodick Published online: 01 July 2014 p442 | doi:10.1038/nrcardio.2014.71-c1 Full Text | PDF
REVIEWS		Top
PET imaging of inflammation in atherosclerosis Jason M. Tarkin, Francis R. Joshi & James H. F. Rudd Published online: 10 June 2014 p443 | doi:10.1038/nrcardio.2014.80 18F-FDG is the most-commonly used tracer in PET imaging of atherosclerosis. 18F-FDG uptake can be used to identify patients at the highest risk of clinical events and as a surrogate end point in clinical trials of antiatherosclerotic therapies. However, background myocardial uptake of 18F-FDG can make identifying high-risk coronary artery plaque difficult. Several novel PET tracers have, therefore, also been tested in atherosclerosis imaging. Here, Tarkin et al. review the role of state-of-the-art PET imaging of inflammation in atherosclerosis, including the rationale for this modality, and its current and future uses. Abstract | Full Text | PDF
Contemporary overview and clinical perspectives of chronic total occlusions Loes P. Hoebers, Bimmer E. Claessen, George D. Dangas, Truls Råmunddal, Roxana Mehran & José P. S. Henriques Published online: 27 May 2014 p458 | doi:10.1038/nrcardio.2014.74 Percutaneous coronary intervention (PCI) for a chronic total occlusion (CTO) is currently infrequently performed due to technical difficulty or perceived risk of complication. In this Review, Hoebers et al. provide a comprehensive overview of CTO-PCI and the selection criteria for those patients who might benefit from the procedure, which the authors believe should be performed more frequently to treat CTOs. The authors also discuss emerging technologies that might improve CTO-PCI. Abstract | Full Text | PDF
Cardiac imaging for assessment of left atrial appendage stasis and thrombosis Jorge Romero, Jie J. Cao, Mario J. Garcia & Cynthia C. Taub Published online: 10 June 2014 p470 | doi:10.1038/nrcardio.2014.77 The left atrial appendage (LAA) is the main location of thrombus formation in patients with atrial fibrillation. This Review by Romero et al. is focused on the pathophysiology, assessment, and clinical implications of stasis and thrombus formation in the LAA. The advantages and disadvantages of the available imaging modalities for LAA assessment are discussed, and the authors explore the role of cardiac imaging in the therapeutic use of LAA closure devices. Abstract | Full Text | PDF
Strategies to improve cardiac resynchronization therapy Kevin Vernooy, Caroline J. M. van Deursen, Marc Strik & Frits W. Prinzen Published online: 20 May 2014 p481 | doi:10.1038/nrcardio.2014.67 Cardiac resynchronization can be a useful therapy for patients with heart failure and abnormal ventricular contraction. However, up to half of patients do not respond to therapy. In this Review, Vernooy and colleagues discuss the selection of patients, positioning of pacing leads, timing of pacing, and management of patients after device implantation to improve the outcomes from cardiac resynchronization therapy. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2012. Nature Reviews Cardiology was previously published as Nature Clinical Practice Cardiovascular Medicine.

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