Nature Reviews Urology - Table of Contents alert Volume 11 Issue 7

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TABLE OF CONTENTS
July 2014 Volume 11 Number 7
Impact Factor 4.793*	In this issue Research Highlights News and Views Reviews Perspectives Correspondence Also this month  Featured article: Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer Woonyoung Choi, Bogdan Czerniak, Andrea Ochoa, Xiaoping Su, Arlene Siefker-Radtke, Colin Dinney & David J. McConkey
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RESEARCH HIGHLIGHTS Top Prostate cancer: Enzalutamide PREVAILs Published online: 17 June 2014 p361 | doi:10.1038/nrurol.2014.139 PDF Prostate cancer: Viral gene therapy can improve IMRT Published online: 17 June 2014 p362 | doi:10.1038/nrurol.2014.138 PDF Prostate cancer: Optimizing active surveillance: patient and protocol Published online: 24 June 2014 p362 | doi:10.1038/nrurol.2014.146 PDF Prostate cancer: Extended pelvic lymph node removal—extended survival Published online: 17 June 2014 p363 | doi:10.1038/nrurol.2014.137 PDF Basic research: Therapeutic action of BCG mediated by H2O2? Published online: 24 June 2014 p364 | doi:10.1038/nrurol.2014.140 PDF Surgery: Retroperitoneoscopic partial nephrectomy: practice is key Published online: 10 June 2014 p365 | doi:10.1038/nrurol.2014.133 PDF Basic research: Urethral sphincter regeneration using stem cells from amniotic fluid Published online: 10 June 2014 p365 | doi:10.1038/nrurol.2014.134 PDF Prostate cancer: Metformin—the new wonder drug? Published online: 10 June 2014 p366 | doi:10.1038/nrurol.2014.136 PDF Prostate cancer: An enzalutamide antiandrogen withdrawal syndrome Published online: 24 June 2014 p366 | doi:10.1038/nrurol.2014.145 PDF IN BRIEF Prostate cancer: Monoamine oxidase A—a therapeutic target? | Male factor infertility: Postacrosomal WW binding protein improves fertilization | Penile cancer: Predictors of cancer-specific mortality | Andrology: Predicting response to clomiphene citrate | From ASCO—prostate cancer: Upfront docetaxel with hormone therapy improves survival | From ASCO—bladder cancer: Promising results for immunotherapy drug | From ASCO—prostate cancer: Docetaxel and abiraterone combination therapy | From ASCO—bladder cancer: Predicting response to neoadjuvant chemotherapy PDF
NEWS AND VIEWS		Top
Testicular cancer: Risk stratification in adolescents with nonseminoma Leendert H. J. Looijenga Published online: 24 June 2014 p367 | doi:10.1038/nrurol.2014.141 Data are lacking on the role of histological risk factors (such as embryonal carcinoma and lymphovascular invasion) for occult metastasis in adolescents with testicular germ cell tumours. Investigators of a pilot study have now retrospectively reviewed a testis cancer database to identify risk stratification criteria in this population. Full Text | PDF
Prostate cancer: Intriguing data on inflammation and prostate cancer Linda Vignozzi & Mario Maggi Published online: 01 July 2014 p369 | doi:10.1038/nrurol.2014.143 A new case-control study shows that inflammation on biopsy is associated with diagnosis of prostate cancer. We think a large population-based prospective study, specifically designed to investigate the longitudinal association between inflammation and subsequent onset of prostate cancer, is required to elucidate the true relationship between inflammation and prostate carcinogenesis. Full Text | PDF
Prostate cancer: Cabazitaxel—the taxane of choice in the new mCRPC landscape? Stéphane Oudard & Antoine Angelergues Published online: 24 June 2014 p370 | doi:10.1038/nrurol.2014.144 Cabazitaxel, a next-generation taxane, retains its efficacy in patients with metastatic castration-resistant prostate cancer (mCRPC) who progress on new androgen receptor (AR)-targeted agents such as abiraterone acetate or enzalutamide. These findings are reinforced by in vitro preclinical data confirming cross-resistance between abiraterone and enzalutamide, but not between cabazitaxel and AR-targeted agents. Full Text | PDF
REVIEWS		Top
Pushing the boundaries of ureteroscopy: current status and future perspectives Petrisor Geavlete, Razvan Multescu & Bogdan Geavlete Published online: 03 June 2014 p373 | doi:10.1038/nrurol.2014.118 Ureteroscopy is a valuable technique for the treatment of urolithiasis and the diagnosis of other upper urinary tract pathologies, including malignancies. In this Review, the technological advances that have improved outcomes and expanded the indications for this retrograde endoscopic approach are discussed, and potential avenues for continued evolution of the methodology are highlighted. Abstract | Full Text | PDF
Diagnosis and management of intradiverticular bladder tumours Nicholas Faure Walker, Christine Gan, Jonathon Olsburgh & Muhammad Shamim Khan Published online: 17 June 2014 p383 | doi:10.1038/nrurol.2014.131 Faure Walker and colleagues review the existing literature on intradiverticular bladder tumours, highlighting the challenges that exist in the management of malignant and premalignant conditions within bladder diverticula. They outline the only guidelines currently available, and provide their own recommendations for the diagnosis and treatment of these conditions. Abstract | Full Text | PDF
Mechanisms of testicular torsion and potential protective agents Ersagun Karaguzel, Mustafa Kadihasanoglu & Omer Kutlu Published online: 17 June 2014 p391 | doi:10.1038/nrurol.2014.135 Testicular torsion is a urological emergency that occurs most commonly in adolescence. In this Review, the authors discuss the pathophysiological mechanisms of testicular torsion and reperfusion injury, before summarizing the large body of preclinical data that exists regarding potential therapies, including antioxidants, hormones, vitamins and plant extracts. Abstract | Full Text | PDF
Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer Woonyoung Choi, Bogdan Czerniak, Andrea Ochoa, Xiaoping Su, Arlene Siefker-Radtke, Colin Dinney & David J. McConkey Published online: 24 June 2014 p400 | doi:10.1038/nrurol.2014.129 New analyses show that muscle-invasive bladder cancers can be grouped into basal and luminal subtypes that are highly reminiscent of those found in breast cancer. Choi and colleagues introduce the newly identified basal and luminal subtypes of muscle-invasive bladder cancer and explain their implications for the clinical management of this disease. Abstract | Full Text | PDF
PERSPECTIVES		Top
ESSAY Fetal therapy for the treatment of congenital bladder neck obstruction Mark D. Kilby & R. Katie Morris Published online: 17 June 2014 p412 | doi:10.1038/nrurol.2014.132 Lower urinary tract obstruction is a morbid congenital anomaly that can be treated prenatally. Kilby & Morris discuss the importance of accurate diagnosis and case selection to optimize outcomes of in utero intervention, before reviewing the evidence and outcome data for in utero vesicostomy, vesicoamniotic shunting and fetal cystoscopy. Abstract | Full Text | PDF
CORRESPONDENCE		Top
A recipe for targeted therapy in prostate cancer Shigeo Masuda & Juan Carlos Izpisua Belmonte Published online: 01 July 2014 p419 | doi:10.1038/nrurol.2013.110-c1 Full Text | PDF
Normoxic regulation of HIF-1α in prostate cancer Weranja K. B. Ranasinghe, Graham S. Baldwin, Arthur Shulkes, Damien Bolton & Oneel Patel Published online: 01 July 2014 p419 | doi:10.1038/nrurol.2013.110-c2 Full Text | PDF
REPLY		Top
Targeting notch in prostate cancer—combination is the key Laure Marignol Published online: 01 July 2014 p419 | doi:10.1038/nrurol.2013.110-c3 Full Text | PDF
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*Journal Citation Reports, Thomson, 2013. Nature Reviews Urology was previously published as Nature Clinical Practice Urology.

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