Scientific Reports Biology Table of Contents e-alert: 1 July 2014

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01 July 2014      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports               Biological Sciences               Semi-supervised learning for potential human microRNA-disease associations inference ▶     Xing Chen, Gui-Ying Yan     MicroRNAs play critical role in the development and progression of various diseases. Predicting potential miRNA-disease associations from vast amount of biological data is an …             Bluffing promotes overconfidence on social networks ▶     Kun Li, Rui Cong, Te Wu et al.     The overconfidence, a well-established bias, in fact leads to unrealistic expectations or faulty assessment. So it remains puzzling why such psychology of self-deception is …             Network dynamics of 3D engineered neuronal cultures: a new experimental model for in-vitro electrophysiology ▶     Monica Frega, Mariateresa Tedesco, Paolo Massobrio et al.     Despite the extensive use of in-vitro models for neuroscientific investigations and notwithstanding the growing field of network electrophysiology, all studies on cultured cells …             Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes ▶     Chi Liu, Ryosuke Kurokawa, Masayuki Fujino et al.     Hydrogen exerts beneficial effects in disease animal models of ischemia-reperfusion injury as well as inflammatory and neurological disease. Additionally, molecular hydrogen is …             The image-scratch paradigm: a new paradigm for evaluating infants' motivated gaze control ▶     Michiko Miyazaki, Hideyuki Takahashi, Matthias Rolf et al.     Human infants show spontaneous behaviours such as general movement, goal-directed behaviour, and self-motivated behaviour from a very early age. However, it is unclear how these …             Preparation of protein imprinted materials by hierarchical imprinting techniques and application in selective depletion of albumin from human serum ▶     Jinxiang Liu, Qiliang Deng, Dingyin Tao et al.     Hierarchical imprinting was developed to prepare the protein imprinted materials, as the artificial antibody, for the selective depletion of HSA from the human serum proteome. …             HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation ▶     Elizabeth Lokich, Rakesh K. Singh, Alex Han et al.     Antiestrogens including tamoxifen and fulvestrant have been evaluated as chemotherapeutics for ovarian cancer, particularly in cases of platinum resistant disease. Human …             Defection and extortion as unexpected catalysts of unconditional cooperation in structured populations ▶     Attila Szolnoki, Matjaž Perc     We study the evolution of cooperation in the spatial prisoner's dilemma game, where besides unconditional cooperation and defection, tit-for-tat, win-stay-lose-shift and extortion …             Decomposition of Phragmites australis litter retarded by invasive Solidago canadensis in mixtures: an antagonistic non-additive effect ▶     Ling Zhang, Yaojun Zhang, Jianwen Zou et al.     Solidago canadensis is an aggressive invader in China. Solidago invasion success is partially attributed to allelopathic compounds release and more benefits from AM fungi, which …             Spectral and structural comparison between bright and dim green fluorescent proteins in Amphioxus ▶     Erin K. Bomati, Joy E. Haley, Joseph P. Noel et al.     The cephalochordate Amphioxus naturally co-expresses fluorescent proteins (FPs) with different brightness, which thus offers the rare opportunity to identify FP molecular …             Subdigital setae of chameleon feet: Friction-enhancing microstructures for a wide range of substrate roughness ▶     Marlene Spinner, Guido Westhoff, Stanislav N. Gorb     Hairy adhesive systems of microscopic setae with triangular flattened tips have evolved convergently in spiders, insects and arboreal lizards. The ventral sides of the feet and …             CORRIGENDUM: FasL Gene -844T/C Mutation of Esophageal Cancer in South China and Its Clinical Significance ▶     Hongguang Zhao, Linfeng Zheng, Xinru Li et al.                 RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus biofilm inhibition by ursolic acid and resveratrol ▶     Nan Qin, Xiaojuan Tan, Yinming Jiao et al.     Bacterial biofilms are particularly problematic since they become resistant to most available antibiotics. Hence, novel potential antagonists to inhibit biofilm formation are …             Real-time Measurement of Membrane Conformational States Induced by Antimicrobial Peptides: Balance Between Recovery and Lysis ▶     Kristopher Hall, Tzong-Hsien Lee, Adam I. Mechler et al.     The disruption of membranes by antimicrobial peptides is a multi-state process involving significant structural changes in the phospholipid bilayer. However, direct measurement of …             Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity ▶     Auke P. Verhaar, Elmer Hoekstra, Angela S. W. Tjon et al.     Space flight strongly moderates human immunity but is in general well tolerated. Elucidation of the mechanisms by which zero gravity interacts with human immunity may provide …             Ataxia telangiectasia derived iPS cells show preserved x-ray sensitivity and decreased chromosomal instability ▶     Yoshihiro Fukawatase, Masashi Toyoda, Kohji Okamura et al.     Ataxia telangiectasia is a neurodegenerative inherited disease with chromosomal instability and hypersensitivity to ionizing radiation. iPS cells lacking ATM (AT-iPS cells) …             Elucidating a Key Anti-HIV-1 and Cancer-Associated Axis: The Structure of CCL5 (Rantes) in Complex with CCR5 ▶     Phanourios Tamamis, Christodoulos A. Floudas     CCL5 (RANTES) is an inflammatory chemokine which binds to chemokine receptor CCR5 and induces signaling. The CCL5:CCR5 associated chemotactic signaling is of critical biological …             Scaling of nitrogen and phosphorus across plant organs in shrubland biomes across Northern China ▶     Xian Yang, Zhiyao Tang, Chengjun Ji et al.     Allocation of limiting resources, such as nutrients, is an important adaptation strategy for plants. Plants may allocate different nutrients within a specific organ or the same …             Genome-wide identification of transcription factors and transcription-factor binding sites in oleaginous microalgae Nannochloropsis ▶     Jianqiang Hu, Dongmei Wang, Jing Li et al.     Nannochloropsis spp. are a group of oleaginous microalgae that harbor an expanded array of lipid-synthesis related genes, yet how they are transcriptionally regulated remains …             Dark-operative protochlorophyllide oxidoreductase generates substrate radicals by an iron-sulphur cluster in bacteriochlorophyll biosynthesis ▶     Jiro Nomata, Toru Kondo, Tadashi Mizoguchi et al.     Photosynthesis converts solar energy to chemical energy using chlorophylls (Chls). In a late stage of biosynthesis of Chls, dark-operative protochlorophyllide (Pchlide) …             Zn2+ Blocks Annealing of Complementary Single-Stranded DNA in a Sequence-Selective Manner ▶     Shunwen Lu     Zinc is the second most abundant trace element essential for all living organisms. In human body, 30–40% of the total zinc ion (Zn2) is localized in the nucleus. Intranuclear free …             Phosphoinositides: Minor Lipids Make a Major Impact on Photoreceptor Cell Functions ▶     Raju V. S. Rajala, Ammaji Rajala, Andrew J. Morris et al.     Activation of the phosphoinositide (PI) cycle generates the second messengers that control various aspects of cellular signaling. We have previously shown that two PI cycle …             Non-invasive analysis of intestinal development in preterm and term infants using RNA-Sequencing ▶     Jason M. Knight, Laurie A. Davidson, Damir Herman et al.     The state and development of the intestinal epithelium is vital for infant health, and increased understanding in this area has been limited by an inability to directly assess …             A preliminary study of the relationship between breast cancer metastasis and loss of heterozygosity by using exome sequencing ▶     Hongsheng Li, Bo Yang, Ke Xing et al.     We explored the feasibility of studying loss of heterozygosity (LOH) by using exome sequencing and compared the differences in genetic LOH between primary breast tumors and …             Baicalin, a metabolite of baicalein with antiviral activity against dengue virus ▶     Ehsan Moghaddam, Boon-Teong Teoh, Sing-Sin Sam et al.     Baicalin, a flavonoid derived from Scutellaria baicalensis, is the main metabolite of baicalein released following administration in different animal models and human. We …             Isolation, plant colonization potential, and phenanthrene degradation performance of the endophytic bacterium Pseudomonas sp. Ph6-gfp ▶     Kai Sun, Juan Liu, Yanzheng Gao et al.     This investigation provides a novel method of endophyte-aided removal of polycyclic aromatic hydrocarbons (PAHs) from plant bodies. A phenanthrene-degrading endophytic bacterium …             Assortative mating between two sympatric closely-related specialists: inferred from molecular phylogenetic analysis and behavioral data ▶     Huai-Jun Xue, Wen-Zhu Li, Xing-Ke Yang     Host plant shifting of phytophagous insects can lead to the formation of host associated differentiation and ultimately speciation. In some cases, host plant specificity alone …             Quorum quenching bacteria Bacillus sp. QSI-1 protect zebrafish (Danio rerio) from Aeromonas hydrophila infection ▶     Weihua Chu, Shuxin Zhou, Wei Zhu et al.     Quorum Sensing (QS) is a bacterial regulatory mechanism, which is responsible for controlling the expression of various biological macromolecules such as the virulence factors in …             Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells ▶     Katsuhiro Uzawa, Atsushi Kasamatsu, Toshihiro Shimizu et al.     No definitive therapy exists to treat human metastatic tumors. We reported previously that down-regulation of Lin-7C is essential for metastasis of human squamous cell carcinomas …             Spatio-temporal mapping of variation potentials in leaves of Helianthus annuus L. seedlings in situ using multi-electrode array ▶     Dong-Jie Zhao, Zhong-Yi Wang, Lan Huang et al.     Damaging thermal stimuli trigger long-lasting variation potentials (VPs) in higher plants. Owing to limitations in conventional plant electrophysiological recording techniques, …             Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice ▶     G. B. Rogers, J. Kozlowska, J. Keeble et al.     Despite the fundamental contribution of the gut microbiota to host physiology, the extent of its variation in genetically-identical animals used in research is not known. We …             Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+γδ T-cells are effective killers of protozoan parasites ▶     R. K. Peckham, R. Brill, D. S. Foster et al.     IL-17 has emerged as a key player in the immune system, exhibiting roles in protection from infectious diseases and promoting inflammation in autoimmunity. Initially thought to be …             A New Biocompatible and Antibacterial Phosphate Free Glass-Ceramic for Medical Applications ▶     Belén Cabal, Luís Alou, Fabio Cafini et al.     In the attempt to find valid alternatives to classic antibiotics and in view of current limitations in the efficacy of antimicrobial-coated or loaded biomaterials, this work is …             Changes of statistical structural fluctuations unveils an early compacted degraded stage of PNS myelin ▶     Nicola Poccia, Gaetano Campi, Alessandro Ricci et al.     Degradation of the myelin sheath is a common pathology underlying demyelinating neurological diseases from Multiple Sclerosis to Leukodistrophies. Although large malformations of …             Controlled glucose consumption in yeast using a transistor-like device ▶     Yang Song, Jiapeng Wang, Siu-Tung Yau     From the point of view of systems biology, insight into controlling the functioning of biological systems is conducive to the understanding of their complexness. The development …             Alternative hypotheses to explain why biodiversity-ecosystem functioning relationships are concave-up in some natural ecosystems but concave-down in manipulative experiments ▶     Camilo Mora, Roberto Danovaro, Michel Loreau     Recent studies of the relationship between biodiversity and functioning in marine ecosystems have yielded non-saturating patterns that contrast sharply with the results of …             Evolutionary optimality in sex differences of longevity and athletic performances ▶     Hiromi Asanuma, Satoshi Kakishima, Hiromu Ito et al.     Many sexual differences are known in human and animals. It is well known that females are superior in longevity, while males in athletic performances. Even though some sexual …             Small molecule inhibitors of HCV replication from Pomegranate ▶     B. Uma Reddy, Ranajoy Mullick, Anuj Kumar et al.     Hepatitis C virus (HCV) is the causative agent of end-stage liver disease. Recent advances in the last decade in anti HCV treatment strategies have dramatically increased the …             Microinjection free delivery of miRNA inhibitor into zygotes ▶     Jin Young Joo, Jonghwan Lee, Hae Young Ko et al.     The development of gene delivery systems into embryos is challenging due to technical difficulties, delivery efficiency and toxicity. Here, we developed an organic compound …             PPARβ/δ activation of CD300a controls intestinal immunity ▶     Toshiya Tanaka, Satoko Tahara-Hanaoka, Tsukasa Nabekura et al.     Macrophages are important for maintaining intestinal immune homeostasis. Here, we show that PPARβ/δ (peroxisome proliferator-activated receptor β/δ) directly regulates CD300a in …             CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes ▶     Yuki Hasegawa, Dave Tang, Naoko Takahashi et al.     Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely …             A Minimally Invasive Method for Retrieving Single Adherent Cells of Different Types from Cultures ▶     Jia Zeng, Aida Mohammadreza, Weimin Gao et al.     The field of single-cell analysis has gained a significant momentum over the last decade. Separation and isolation of individual cells is an indispensable step in almost all …             Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling ▶     Jian-Guo Ren, Pankaj Seth, Clary B. Clish et al.     Mitochondrial malic enzyme 2 (ME2) catalyzes the oxidative decarboxylation of malate to yield CO2 and pyruvate, with concomitant reduction of dinucleotide cofactor NAD or NADP. We …             Two different approaches for pharmacokinetic modeling of exhaled drug concentrations ▶     S. Kreuer, A. Hauschild, T. Fink et al.     Online measurement of drug concentrations in patient's breath is a promising approach for individualized dosage. A direct transfer from breath- to blood-concentrations is not …                     A new online open access multi-and interdisciplinary journal dedicated to publishing the finest research on microbial biofilms and microbiomes. 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