TABLE OF CONTENTS |  |  |  | Volume 35, Issue 8 (August 2014) |  | In this issue Review Original Articles
Also new    AOP
| |  |  |  | | Advertisement |  | | |  |  | Review | Top |  | Alcohol use disorders and current pharmacological therapies: the role of GABAA receptors Jing Liang and Richard W Olsen Acta Pharmacol Sin 2014 35: 981-993; 10.1038/aps.2014.50 Abstract | Full Text |  | Original Articles | Top |  | MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression Hong Yan, Yan-ling Ma, Yu-zhou Gui, Shu-mei Wang, Xin-bo Wang, Fei Gao and Yi-ping Wang Acta Pharmacol Sin 2014 35: 994-1004; advance online publication, July 21, 2014; 10.1038/aps.2014.52 Abstract | Full Text |  |  |  | Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice Li-qing Weng, Wen-bin Zhang, Yong Ye, Pei-pei Yin, Jie Yuan, Xing-xu Wang, Le Kang, Sha-sha Jiang, Jie-yun You, Jian Wu, Hui Gong, Jun-bo Ge and Yun-zeng Zou Acta Pharmacol Sin 2014 35: 1005-1014; advance online publication, July 7, 2014; 10.1038/aps.2014.45 Abstract | Full Text |  |  |  | Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice Fan Fan, Quan Cao, Cong Wang, Xin Ma, Cheng Shen, Xiang-wei Liu, Li-ping Bu, Yun-zeng Zou, Kai Hu, Ai-jun Sun and Jun-bo Ge Acta Pharmacol Sin 2014 35: 1015-1022; advance online publication, July 7, 2014; 10.1038/aps.2014.46 Abstract | Full Text |  |  |  | Somatostatin receptor type 2 contributes to the self-renewal of murine embryonic stem cells Xin-xiu Xu, Li-hong Zhang and Xin Xie Acta Pharmacol Sin 2014 35: 1023-1030; advance online publication, July 7, 2014; 10.1038/aps.2014.51 Abstract | Full Text |  |  |  | Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis Jian-ping Li, Yan Gao, Shi-feng Chu, Zhao Zhang, Cong-yuan Xia, Zheng Mou, Xiu-yun Song, Wen-bin He, Xiao-feng Guo and Nai-hong Chen Acta Pharmacol Sin 2014 35: 1031-1044; advance online publication, June 30, 2014; 10.1038/aps.2014.41 Abstract | Full Text |  |  |  | Inhibition of STAT3 acetylation is associated with angiotesin renal fibrosis in the obstructed kidney Jun Ni, Yang Shen, Zhen Wang, De-cui Shao, Jia Liu, Lan-jun Fu, Ya-li Kong, Li Zhou, Hong Xue, Yu Huang, Wei Zhang, Chen Yu and Li-min Lu Acta Pharmacol Sin 2014 35: 1045-1054; advance online publication, June 30, 2014; 10.1038/aps.2014.42 Abstract | Full Text |  |  |  | G226, a novel epipolythiodioxopiperazine derivative, induces autophagy and caspase-dependent apoptosis in human breast cancer cells in vitro Peng-xing He, Yong-sheng Che, Qiao-jun He, Yi Chen and Jian Ding Acta Pharmacol Sin 2014 35: 1055-1064; 10.1038/aps.2014.47 Abstract | Full Text |  |  |  | α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway Tao Shan, Xi-juan Cui, Wei Li, Wan-run Lin, Hong-wei Lu, Yi-ming Li, Xi Chen and Tao Wu Acta Pharmacol Sin 2014 35: 1065-1073; advance online publication, June 30, 2014; 10.1038/aps.2014.43 Abstract | Full Text |  |  |  | Discovering novel anti-HCV compounds with inhibitory activities toward HCV NS3/4A protease Ye Yu, Jing-feng Jing, Xian-kun Tong, Pei-lan He, Yuan-chao Li, You-hong Hu, Wei Tang and Jian-ping Zuo Acta Pharmacol Sin 2014 35: 1074-1081; advance online publication, July 21, 2014; 10.1038/aps.2014.55 Abstract | Full Text |  |  |  | Discovery of novel aromatase inhibitors using a homogeneous time-resolved fluorescence assay Jin-zi Ji, Ke-jing Lao, Jie Hu, Tao Pang, Zhen-zhou Jiang, Hao-liang Yuan, Jing-shan Miao, Xin Chen, Shan-shan Ning, Hua Xiang, Yu-meng Guo, Ming Yan and Lu-yong Zhang Acta Pharmacol Sin 2014 35: 1082-1092; advance online publication, July 21, 2014; 10.1038/aps.2014.51 Abstract | Full Text |  |  |  | Novel Bayesian classification models for predicting compounds blocking hERG potassium channels Li-li Liu, Jing Lu, Yin Lu, Ming-yue Zheng, Xiao-min Luo, Wei-liang Zhu, Hua-liang Jiang and Kai-xian Chen Acta Pharmacol Sin 2014 35: 1093-1102; advance online publication, June 30, 2014; 10.1038/aps.2014.35 Abstract | Full Text |  |  |  |  | | Advertisement |  | Submit Your Next Paper to APS
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