Acta Pharmacologica Sinica - Table of Contents alert Volume 36 Issue 1

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Nuclear receptors are DNA-binding and ligand-regulated transcriptional factors that play crucial roles in many aspects of human physiology and consist of an important family of drug targets. This year marked the 30th anniversary of the cloning of the first member of the nuclear receptor family and 25th year of the discovery of orphan nuclear receptors, for which no cognate ligands were known at the time of their cloning. Since then we have witnessed a tremendous expansion of our knowledge of this family of receptors. In this special issue, 11 review articles highlight our key understanding of structure, function, disease relevance, and drug discovery of nuclear receptors. TABLE OF CONTENTS Volume 36, Issue 1 (January 2015) In this issue Editorial Reviews Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Editorial Top Family reunion of nuclear hormone receptors: structures, diseases, and drug discovery H Eric Xu Acta Pharmacol Sin 2015 36: 1-2; 10.1038/aps.2014.140 Full Text | PDF Reviews Top Androgen receptor: structure, role in prostate cancer and drug discovery OPEN MH Eileen Tan, Jun Li, H Eric Xu, Karsten Melcher and Eu-leong Yong Acta Pharmacol Sin 2015 36: 3-23; advance online publication, June 9, 2014; 10.1038/aps.2014.18 Abstract | Full Text Identification of estrogen-responsive genes based on the DNA binding properties of estrogen receptors using high-throughput sequencing technology Kazuhiro Ikeda, Kuniko Horie-Inoue and Satoshi Inoue Acta Pharmacol Sin 2015 36: 24-31; advance online publication, December 15, 2014; 10.1038/aps.2014.123 Abstract | Full Text The role of the orphan nuclear receptor COUP-TFII in tumorigenesis OPEN Mafei Xu, Jun Qin, Sophia Y Tsai and Ming-jer Tsai Acta Pharmacol Sin 2015 36: 32-36; advance online publication, October 6, 2014; 10.1038/aps.2014.86 Abstract | Full Text FXR and liver carcinogenesis Xiong-fei Huang, Wei-yu Zhao and Wen-dong Huang Acta Pharmacol Sin 2015 36: 37-43; advance online publication, December 15, 2014; 10.1038/aps.2014.117 Abstract | Full Text Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis Yang Jiao, Yan Lu and Xiao-ying Li Acta Pharmacol Sin 2015 36: 44-50; advance online publication, December 15, 2014; 10.1038/aps.2014.116 Abstract | Full Text The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases Étienne Audet-walsh and Vincent Giguére Acta Pharmacol Sin 2015 36: 51-61; advance online publication, December 15, 2014; 10.1038/aps.2014.121 Abstract | Full Text Deciphering the roles of the constitutive androstane receptor in energy metabolism Jiong Yan, Baian Chen, Jing Lu and Wen Xie Acta Pharmacol Sin 2015 36: 62-70; advance online publication, December 15, 2014; 10.1038/aps.2014.102 Abstract | Full Text ROR nuclear receptors: structures, related diseases, and drug discovery Yan Zhang, Xiao-yu Luo, Dong-hai Wu and Yong Xu Acta Pharmacol Sin 2015 36: 71-87; advance online publication, December 15, 2014; 10.1038/aps.2014.120 Abstract | Full Text A structural perspective on nuclear receptors as targets of environmental compounds Vanessa Delfosse, Albane le Maire, Patrick Balaguer and William Bourguet Acta Pharmacol Sin 2015 36: 88-101; advance online publication, December 15, 2014; 10.1038/aps.2013.133 Abstract | Full Text Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites Xiao-kun Zhang, Ying Su, Liqun Chen, Fan Chen, Jie Liu and Hu Zhou Acta Pharmacol Sin 2015 36: 102-112; advance online publication, December 1, 2014; 10.1038/aps.2014.109 Abstract | Full Text Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis Shuangwei Li, Andrew Ni and Gen-sheng Feng Acta Pharmacol Sin 2015 36: 113-118; advance online publication, December 15, 2014; 10.1038/aps.2014.118 Abstract | Full Text Original Articles Top Sitagliptin protects rat kidneys from acute ischemia-reperfusion injury via upregulation of GLP-1 and GLP-1 receptors Meng-wei Chang, Chih-hung Chen, Yi-ching Chen, Ying-chun Wu, Yen-yi Zhen, Steve Leu, Tzu-hsien Tsai, Sheung-fat Ko, Pei-hsun Sung, Chih-chau Yang, Hsin-ju Chiang, Hsueh-wen Chang, Yen-ta Chen and Hon-kan Yip Acta Pharmacol Sin 2015 36: 119-130; advance online publication, December 15, 2014; 10.1038/aps.2014.98 Abstract | Full Text β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation Hai-bing Wang and Xiao-qiong Ma Acta Pharmacol Sin 2015 36: 131-138; advance online publication, December 1, 2014; 10.1038/aps.2014.108 Abstract | Full Text Oral delivery of capsaicin using MPEG-PCL nanoparticles Wei Peng, Xin-yi Jiang, Yuan Zhu, E Omari-Siaw, Wen-wen Deng, Jiang-nan Yu, Xi-ming Xu and Wei-ming Zhang Acta Pharmacol Sin 2015 36: 139-148; advance online publication, December 1, 2014; 10.1038/aps.2014.113 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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