Molecular Therapy - Table of Contents alert Volume 23 Issue 1

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TABLE OF CONTENTS Volume 23, Issue 1 (January 2015) In this issue Editorial In This Issue Research Highlights Commentary Original Articles Corrigendum Sign up for e-alerts Recommend to your library Web feed Subscribe Editorial Top The Molecular Therapy Family: Past, Present, and Future Seppo Ylä-Herttuala Mol Ther 2015 23: 1; 10.1038/mt.2014.227 Full Text In This Issue Top In This Issue Mol Ther 2015 23: 2; 10.1038/mt.2014.228 Full Text Research Highlights Top Research Highlights Mol Ther 2015 23: 3; 10.1038/mt.2014.229 Full Text Commentary Top Hitting the Target Without Pulling the Trigger Thierry VandenDriessche and Marinee K Chuah Mol Ther 2015 23: 4-6; 10.1038/mt.2014.230 Full Text Original Articles Top Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice Emilie Macé, Romain Caplette, Olivier Marre, Abhishek Sengupta, Antoine Chaffiol, Peggy Barbe, Mélissa Desrosiers, Ernst Bamberg, Jose-Alain Sahel, Serge Picaud, Jens Duebel and Deniz Dalkara Mol Ther 2015 23: 7-16; advance online publication, August 6, 2014; 10.1038/mt.2014.154 Abstract | Full Text Fractalkine Over Expression Suppresses α-Synuclein-mediated Neurodegeneration Kevin R Nash, Peter Moran, Dylan J Finneran, Charles Hudson, Jesse Robinson, Dave Morgan and Paula C Bickford Mol Ther 2015 23: 17-23; advance online publication, September 8, 2014; 10.1038/mt.2014.175 Abstract | Full Text A Functional Variant of Elafin With Improved Anti-inflammatory Activity for Pulmonary Inflammation Donna M Small, Marie-Louise Zani, Derek J Quinn, Sandrine Dallet-Choisy, Arlene MA Glasgow, Cecilia O'Kane, Danny F McAuley, Paul McNally, Sinéad Weldon, Thierry Moreau and Clifford C Taggart Mol Ther 2015 23: 24-31; advance online publication, September 5, 2014; 10.1038/mt.2014.162 Abstract | Full Text EZH2 Modulates Angiogenesis In Vitro and in a Mouse Model of Limb IschemiaMTOPEN Tijana Mitić, Andrea Caporali, Ilaria Floris, Marco Meloni, Micol Marchetti, Raul Urrutia, Gianni D Angelini and Costanza Emanueli Mol Ther 2015 23: 32-42; advance online publication, September 5, 2014; 10.1038/mt.2014.163 Abstract | Full Text Genome-wide Computational Analysis Reveals Cardiomyocyte-specific Transcriptional Cis-regulatory Motifs That Enable Efficient Cardiac Gene TherapyMTOPEN Melvin Y Rincon, Shilpita Sarcar, Dina Danso-Abeam, Marleen Keyaerts, Janka Matrai, Ermira Samara-Kuko, Abel Acosta-Sanchez, Takis Athanasopoulos, George Dickson, Tony Lahoutte, Pieter De Bleser, Thierry VandenDriessche and Marinee K Chuah Mol Ther 2015 23: 43-52; advance online publication, September 8, 2014; 10.1038/mt.2014.178 Abstract | Full Text Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice Jacob I Ayers, Susan Fromholt, Olga Sinyavskaya, Zoe Siemienski, Awilda M Rosario, Andrew Li, Keith W Crosby, Pedro E Cruz, Nadia M DiNunno, Christopher Janus, Carolina Ceballos-Diaz, David R Borchelt, Todd E Golde, Paramita Chakrabarty and Yona Levites Mol Ther 2015 23: 53-62; advance online publication, September 17, 2014; 10.1038/mt.2014.180 Abstract | Full Text CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells Christian Brendel, Benjamin Goebel, Abriss Daniela, Martijn Brugman, Sabrina Kneissl, Joachim Schwäble, Kerstin B Kaufmann, Uta Müller-Kuller, Hana Kunkel, Linping Chen-Wichmann, Tobias Abel, Hubert Serve, Leonid Bystrykh, Christian J Buchholz and Manuel Grez Mol Ther 2015 23: 63-70; advance online publication, September 5, 2014; 10.1038/mt.2014.173 Abstract | Full Text Antitumor Activity of miR-1280 in Melanoma by Regulation of Src Vera Sun, Wen B Zhou, Mehdi Nosrati, Shahana Majid, Suresh Thummala, David de Semir, Vladimir Bezrookove, Sebastien de Feraudy, Liane Chun, Dirk Schadendorf, Robert Debs, Mohammed Kashani-Sabet and Altaf A Dar Mol Ther 2015 23: 71-78; advance online publication, September 8, 2014; 10.1038/mt.2014.176 Abstract | Full Text Baculovirus-Mediated miRNA Regulation to Suppress Hepatocellular Carcinoma Tumorigenicity and Metastasis Chiu-Ling Chen, Jaw-Ching Wu, Guan-Yu Chen, Pei-Hsiang Yuan, Yen-Wen Tseng, Kuei-Chang Li, Shiaw-Min Hwang and Yu-Chen Hu Mol Ther 2015 23: 79-88; advance online publication, July 15, 2014; 10.1038/mt.2014.126 Abstract | Full Text miR-382 Inhibits Osteosarcoma Metastasis and Relapse by Targeting Y Box-Binding Protein 1 Meng Xu, Hua Jin, Cheng-Xiong Xu, Bo Sun, Zhi-Gang Song, Wen-Zhi Bi and Yan Wang Mol Ther 2015 23: 89-98; advance online publication, October 8, 2014; 10.1038/mt.2014.197 Abstract | Full Text Use of miRNA Response Sequences to Block Off-target Replication and Increase the Safety of an Unattenuated, Glioblastoma-targeted Oncolytic HSV Lucia Mazzacurati, Marco Marzulli, Bonnie Reinhart, Yoshitaka Miyagawa, Hiroaki Uchida, William F Goins, Aofei Li, Balveen Kaur, Michael Caligiuri, Timothy Cripe, Nino Chiocca, Nduka Amankulor, Justus B Cohen, Joseph C Glorioso and Paola Grandi Mol Ther 2015 23: 99-107; advance online publication, September 9, 2014; 10.1038/mt.2014.177 Abstract | Full Text Encapsulated Stem Cells Loaded With Hyaluronidase-expressing Oncolytic Virus for Brain Tumor Therapy Jordi Martinez-Quintanilla, Derek He, Hiroaki Wakimoto, Ramon Alemany and Khalid Shah Mol Ther 2015 23: 108-118; advance online publication, October 29, 2014; 10.1038/mt.2014.204 Abstract | Full Text Interventional Magnetic Resonance Imaging-guided Cell Transplantation Into the Brain With Radially Branched Deployment Matthew T Silvestrini, Dali Yin, Alastair J Martin, Valerie G Coppes, Preeti Mann, Paul S Larson, Philip A Starr, Xianmin Zeng, Nalin Gupta, S S Panter, Tejal A Desai and Daniel A Lim Mol Ther 2015 23: 119-129; advance online publication, August 20, 2014; 10.1038/mt.2014.155 Abstract | Full Text Mesenchymal Stem Cells Improve Motor Functions and Decrease Neurodegeneration in Ataxic Mice Jonathan Jones, Alicia Estirado, Carolina Redondo, Jesus Pacheco-Torres, Maria-Salomé Sirerol-Piquer, José M Garcia-Verdugo and Salvador Martinez Mol Ther 2015 23: 130-138; advance online publication, July 29, 2014; 10.1038/mt.2014.143 Abstract | Full Text Mesenchymal Stem/Stromal Cells Protect the Ocular Surface by Suppressing Inflammation in an Experimental Dry Eye Min Joung Lee, Ah Young Ko, Jung Hwa Ko, Hyun Ju Lee, Mee Kum Kim, Won Ryang Wee, Sang In Khwarg and Joo Youn Oh Mol Ther 2015 23: 139-146; advance online publication, August 25, 2014; 10.1038/mt.2014.159 Abstract | Full Text An AAVS1-Targeted Minigene Platform for Correction of iPSCs From All Five Types of Chronic Granulomatous Disease Randall K Merling, Colin L Sweeney, Jessica Chu, Aaron Bodansky, Uimook Choi, Debra Long Priel, Douglas B Kuhns, Hongmei Wang, Sam Vasilevsky, Suk See De Ravin, Thomas Winkler, Cynthia E Dunbar, Jizhong Zou, Kol A Zarember, John I Gallin, Steven M Holland and Harry L Malech Mol Ther 2015 23: 147-157; advance online publication, October 7, 2014; 10.1038/mt.2014.195 Abstract | Full Text SCL/TAL1-mediated Transcriptional Network Enhances Megakaryocytic Specification of Human Embryonic Stem Cells Miguel G Toscano, Oscar Navarro-Montero, Veronica Ayllon, Veronica Ramos-Mejia, Xiomara Guerrero-Carreno, Clara Bueno, Tamara Romero, Mar Lamolda, Marien Cobo, Francisco Martin, Pablo Menendez and Pedro J Real Mol Ther 2015 23: 158-170; advance online publication, October 8, 2014; 10.1038/mt.2014.196 Abstract | Full Text Engager T Cells: A New Class of Antigen-specific T Cells That Redirect Bystander T Cells Kota Iwahori, Sunitha Kakarla, Mireya P Velasquez, Feng Yu, Zongzhen Yi, Claudia Gerken, Xiao-Tong Song and Stephen Gottschalk Mol Ther 2015 23: 171-178; advance online publication, August 21, 2014; 10.1038/mt.2014.156 Abstract | Full Text Graft Versus Leukemia Response Without Graft-versus-host Disease Elicited By Adoptively Transferred Multivirus-specific T-cells Jan J Melenhorst, Paul Castillo, Patrick J Hanley, Michael D Keller, Robert A Krance, Judith Margolin, Ann M Leen, Helen E Heslop, A John Barrett, Cliona M Rooney and Catherine M Bollard Mol Ther 2015 23: 179-183; advance online publication, September 30, 2014; 10.1038/mt.2014.192 Abstract | Full Text Treatment of CD33-directed Chimeric Antigen Receptor-modified T Cells in One Patient With Relapsed and Refractory Acute Myeloid Leukemia Quan-shun Wang, Yao Wang, Hai-yan Lv, Qing-wang Han, Hui Fan, Bo Guo, Li-li Wang and Wei-dong Han Mol Ther 2015 23: 184-191; advance online publication, September 1, 2014; 10.1038/mt.2014.164 Abstract | Full Text A Phase 1/2a Follistatin Gene Therapy Trial for Becker Muscular Dystrophy Jerry R Mendell, Zarife Sahenk, Vinod Malik, Ana M Gomez, Kevin M Flanigan, Linda P Lowes, Lindsay N Alfano, Katherine Berry, Eric Meadows, Sarah Lewis, Lyndsey Braun, Kim Shontz, Maria Rouhana, Kelly Reed Clark, Xiomara Q Rosales, Samiah Al-Zaidy, Alessandra Govoni, Louise R Rodino-Klapac, Mark J Hogan and Brian K Kaspar Mol Ther 2015 23: 192-201; advance online publication, October 17, 2014; 10.1038/mt.2014.200 Abstract | Full Text First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity Herbert J Zeh, Stephanie Downs-Canner, J Andrea McCart, Zong Sheng Guo, Uma N M Rao, Lekshmi Ramalingam, Stephen H Thorne, Heather L Jones, Pawel Kalinski, Eva Wieckowski, Mark E O'Malley, Manijeh Daneshmand, Kang Hu, John C Bell, Tae-Ho Hwang, Anne Moon, Caroline J Breitbach, David H Kirn and David L Bartlett Mol Ther 2015 23: 202-214; advance online publication, October 8, 2014; 10.1038/mt.2014.194 Abstract | Full Text Corrigendum Top Corrigendum to “Use of miRNA Response Sequences to Block Off-target Replication and Increase the Safety of an Unattenuated, Glioblastoma-targeted Oncolytic HSV” Mol Ther 2015 23: 215; 10.1038/mt.2014.216 Full Text Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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