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2015/01/13

Scientific Reports Table of Contents e-alert: 13 January 2015

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  13 January 2015   
 
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Asymmetrical disassortative pollination in a distylous primrose: the complementary roles of bumblebee nectar robbers and syrphid flies

 
 

Xing-Fu Zhu, Xian-Feng Jiang, Li Li et al.

 
 

Heterostyly is a floral polymorphism characterized by reciprocal herkogamy maintained through high levels of mating between morphs, serviced by appropriate pollinators. We …

 
 
 
 
 
 

3D-Printed Microfluidic Device for the Detection of Pathogenic Bacteria Using Size-based Separation in Helical Channel with Trapezoid Cross-Section

 
 

Wonjae Lee, Donghoon Kwon, Woong Choi et al.

 
 

A facile method has been developed to detect pathogenic bacteria using magnetic nanoparticle clusters (MNCs) and a 3D-printed helical microchannel. Antibody-functionalized MNCs …

 
 
 
 
 
 

The effects of disruptions in ribosomal active sites and in intersubunit contacts on ribosomal degradation in Escherichia coli

 
 

Anton Paier, Margus Leppik, Aksel Soosaar et al.

 
 

Although ribosomes are very stable under most conditions, ribosomal degradation does occur in diverse groups of organisms in response to specific stresses or environmental …

 
 
 
 
 
 

Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level

 
 

Anton P. Pereverzev, Nadya G. Gurskaya, Galina V. Ermakova et al.

 
 

Nonsense-mediated mRNA decay (NMD) is a ubiquitous mechanism of degradation of transcripts with a premature termination codon. NMD eliminates aberrant mRNA species derived from …

 
 
 
 
 
 

Water balance altered in cucumber plants infected with Fusarium oxysporum f. sp. cucumerinum

 
 

Min Wang, Yuming Sun, Guomei Sun et al.

 
 

Fusarium wilt is caused by the infection and growth of the fungus Fusarium oxysporum in the xylem of host plants. The physiological responses of cucumbers that are infected with

 
 
 
 
 
 

Multiplex Imaging and Cellular Target Identification of Kinase Inhibitors via an Affinity-Based Proteome Profiling Approach

 
 

Ying Su, Sijun Pan, Zhengqiu Li et al.

 
 

MLN8237 is a highly potent and presumably selective inhibitor of Aurora kinase A (AKA) and has shown promising antitumor activities. Like other kinase inhibitors which target the …

 
 
 
 
 
 

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

 
 

Sophie E. Darch, Alan McNally, Freya Harrison et al.

 
 

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant …

 
 
 
 
 
 

Dendritic spine dynamics leading to spine elimination after repeated inductions of LTD

 
 

Sho Hasegawa, Shigeo Sakuragi, Keiko Tominaga-Yoshino et al.

 
 

Memory is fixed solidly by repetition. However, the cellular mechanism underlying this repetition-dependent memory consolidation/reconsolidation remains unclear. In our previous …

 
 
 
 
 
 

The effects of phytochrome-mediated light signals on the developmental acquisition of photoperiod sensitivity in rice

 
 

Yoshihiro Yoshitake, Takayuki Yokoo, Hiroki Saito et al.

 
 

Plants commonly rely on photoperiodism to control flowering time. Rice development before floral initiation is divided into two successive phases: the basic vegetative growth …

 
 
 
 
 
 

Palladin is Upregulated in Kidney Disease and Contributes to Epithelial Cell Migration After Injury

 
 

Emily H. Chang, Adil H. Gasim, Michael L. Kerber et al.

 
 

Recovery from acute kidney injury involving tubular epithelial cells requires proliferation and migration of healthy cells to the area of injury. In this study, we show that …

 
 
 
 
 
 

Silencing SlELP2L, a tomato Elongator complex protein 2-like gene, inhibits leaf growth, accelerates leaf, sepal senescence, and produces dark-green fruit

 
 

Mingku Zhu, Yali Li, Guoping Chen et al.

 
 

The multi-subunit complex Elongator interacts with elongating RNA polymerase II (RNAPII) and is thought to facilitate transcription through histone acetylation. Elongator is …

 
 
 
 
 
 

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production

 
 

Lidia Daszkiewicz, Cristina Vázquez-Mateo, Gorjana Rackov et al.

 
 

Self/non-self discrimination characterizes immunity and allows responses against pathogens but not self-antigens. Understanding the principles that govern this process is …

 
 
 
 
 
 

Epigenetic Heterogeneity in HIV-1 Latency Establishment

 
 

Yuka Matsuda, Mie Kobayashi-Ishihara, Dai Fujikawa et al.

 
 

Despite prolonged antiretroviral therapy, HIV-1 persists as transcriptionally inactive proviruses. The HIV-1 latency remains a principal obstacle in curing AIDS. It is important …

 
 
 
 
 
 

Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration

 
 

Fuxiang Ye, Hiroki Kaneko, Yosuke Nagasaka et al.

 
 

Choroidal neovascularization (CNV) is the main pathogenesis of age-related macular degeneration (AMD), which leads to severe vision loss in many aged patients in most advanced …

 
 
 
 
 
 

Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells

 
 

Jianhong Yang, Yongzhao Zhou, Xia Cheng et al.

 
 

To overcome drug resistance caused by apoptosis deficiency in patients with non-small cell lung carcinoma (NSCLC), there is a need to identify other means of triggering …

 
 
 
 
 
 

A Highly Efficient Approach to Protein Interactome Mapping Based on Collaborative Filtering Framework

 
 

Xin Luo, Zhuhong You, Mengchu Zhou et al.

 
 

The comprehensive mapping of protein-protein interactions (PPIs) is highly desired for one to gain deep insights into both fundamental cell biology processes and the pathology of …

 
 
 
 
 
 

A unique mechanism of successful fertilization in a domestic bird

 
 

Tomohiro Sasanami, Shunsuke Izumi, Naoki Sakurai et al.

 
 

Fertilization is an indispensable step for formation of a zygote in sexual reproduction, leading to species survival. When mating occurs, sperm is transported to the female …

 
 
 
 
 
 

Decreased deformability of lymphocytes in chronic lymphocytic leukemia

 
 

Yi Zheng, Jun Wen, John Nguyen et al.

 
 

This paper reports the first study of stiffness/deformability changes of lymphocytes in chronic lymphocytic leukemia (CLL) patients, demonstrating that at the single cell level, …

 
 
 
 
 
 

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C

 
 

Sara R. Selitsky, Jeanette Baran-Gale, Masao Honda et al.

 
 

Persistent infections with hepatitis B virus (HBV) or hepatitis C virus (HCV) account for the majority of cases of hepatic cirrhosis and hepatocellular carcinoma (HCC) worldwide. …

 
 
 
 
 
 

Consumption of Bt rice pollen containing Cry1C or Cry2A does not pose a risk to Propylea japonica (Thunberg) (Coleoptera: Coccinellidae)

 
 

Yunhe Li, Xiaojie Zhang, Xiuping Chen et al.

 
 

As a pollen feeder, Propylea japonica would be directly exposed to Cry proteins in Bacillus thuringiensis (Bt)-transgenic rice fields. The effect of Cry1C- or Cry2A-containing …

 
 
 
 
 
 

Characterization and immunological activity of different forms of recombinant secreted Hc of botulinum neurotoxin serotype B products expressed in yeast

 
 

Bo Liu, DanYang Shi, ShaoHong Chang et al.

 
 

The recombinant Hc proteins of botulinum neurotoxins and tetanus toxin are exclusively produced by intracellular heterologous expression in Pichia pastoris for use in subunit …

 
 
 
 
 
 

Differential profiles of direct and indirect modification of vector feeding behaviour by a plant virus

 
 

Wen-Bo He, Jie Li, Shu-Sheng Liu

 
 

Plant viruses interact with their insect vectors directly and indirectly via host plants, and this tripartite interaction may produce fitness benefits to both the vectors and the …

 
 
 
 
 
 

Control of microtubule trajectory within an electric field by altering surface charge density

 
 

Naoto Isozaki, Suguru Ando, Tasuku Nakahara et al.

 
 

One of challenges for using microtubules (MTs) driven by kinesin motors in microfluidic environments is to control their direction of movement. Although applying physical biases …

 
 
 
 
 
 

β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure

 
 

Yao Wang, Jiamin Yuan, Zhiyong Qian et al.

 
 

β2-AR activation increases the risk of sudden cardiac death (SCD) in heart failure (HF) patients. Non-selective β-AR blockers have greater benefits on survival than selective …

 
 
 
 
 
 

A conserved P-loop anchor limits the structural dynamics that mediate nucleotide dissociation in EF-Tu

 
 

Evan Mercier, Dylan Girodat, Hans-Joachim Wieden

 
 

The phosphate-binding loop (P-loop) is a conserved sequence motif found in mononucleotide-binding proteins. Little is known about the structural dynamics of this region and its …

 
 
 
 
 
 

Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair

 
 

Francesco Marchetti, Jack Bishop, John Gingerich et al.

 
 

De novo point mutations and chromosomal structural aberrations (CSA) detected in offspring of unaffected parents show a preferential paternal origin with higher risk for older …

 
 
 
 
 
 

The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection

 
 

Fei Huang, Weishan Huang, Jessica Briggs et al.

 
 

Vaccine efficacy depends on strong long-term development of immune memory and the formation of memory CD8 T cells is critical for recall responses to infection. Upon antigen …

 
 
 
 
 
 

Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy

 
 

Ilya Chumakov, Serguei Nabirotchkin, Nathalie Cholet et al.

 
 

Alzheimer disease (AD) represents a major medical problem where mono-therapeutic interventions demonstrated only a limited efficacy so far. We explored the possibility of …

 
 
 
 
 
 

Enhanced multiple vibrational resonances by Na+ and K+ dynamics in a neuron model

 
 

Xing-Xing Wu, Chenggui Yao, Jianwei Shuai

 
 

Some neuronal receptors perceive external input in the form of hybrid periodic signals. The signal detection may be based on the mechanism of vibrational resonance, in which a …

 
 
 
 
 
 

The Effectiveness of RECIST on Survival in Patients with NSCLC Receiving Chemotherapy with or without Target Agents as First-Line Treatment

 
 

Ting Zhou, Lie Zheng, Zhihuang Hu et al.

 
 

We analyzed the correlation between survival and antitumor effect evaluated by RECIST in advanced NSCLC patients with chemotherapy plus target therapy or not as first-line …

 
 
 
 
 
 

HPV16 early gene E5 specifically reduces miRNA-196a in cervical cancer cells

 
 

Chanzhen Liu, Jianfei Lin, Lianqin Li et al.

 
 

High-risk human papillomavirus (HPV) type 16, which is responsible for greater than 50% of cervical cancer cases, is the most prevalent and lethal HPV type. However, the …

 
 
 
 
 
 

Deep down on a Caribbean reef: lower mesophotic depths harbor a specialized coral-endosymbiont community

 
 

Pim Bongaerts, Pedro R. Frade, Kyra B. Hay et al.

 
 

The composition, ecology and environmental conditions of mesophotic coral ecosystems near the lower limits of their bathymetric distributions remain poorly understood. Here we …

 
 
 
 
 
 

Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K

 
 

Naoya Yamaguchi, Takeomi Mizutani, Kazushige Kawabata et al.

 
 

Collective cell migration plays a crucial role in several biological processes, such as embryonic development, wound healing, and cancer metastasis. Here, we focused on …

 
 
 
 
 
 

Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection

 
 

Muhammad Ayaz Anwar, Suresh Panneerselvam, Masaud Shah et al.

 
 

TLR4 in complex with MD2 senses the presence of lipid A (LA) and initiates a signaling cascade that curb the infection. This complex is evolutionarily conserved and can initiate …

 
 
 
 
 
 

Three CCT domain-containing genes were identified to regulate heading date by candidate gene-based association mapping and transformation in rice

 
 

Li Zhang, Qiuping Li, Haijiao Dong et al.

 
 

CCT domain-containing genes generally control flowering in plants. Currently, only six of the 41 CCT family genes have been confirmed to control flowering in rice. To efficiently …

 
 
 
 
 
 

Plectoneme tip bubbles: Coupled denaturation and writhing in supercoiled DNA

 
 

Christian Matek, Thomas E. Ouldridge, Jonathan P. K. Doye et al.

 
 

We predict a novel conformational regime for DNA, where denaturation bubbles form at the tips of plectonemes, and study its properties using coarse-grained simulations. For …

 
 
 
 
 
 

PIP2-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6

 
 

Marina A. Kasimova, Mark A. Zaydman, Jianmin Cui et al.

 
 

Among critical aspects of voltage-gated potassium (Kv) channels' functioning is the effective communication between their two composing domains, the voltage sensor (VSD) and the …

 
 
 
 
 
 

Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress

 
 

Yong-Juan Xin, Bo Yuan, Bin Yu et al.

 
 

Epigenetic regulations including DNA methylation and demethylation play critical roles in neural development. However, whether DNA methylation and demethylation may play a role …

 
 
 
 
 
 

Hyaluronic acid prevents immunosuppressive drug-induced ovarian damage via up-regulating PGRMC1 expression

 
 

Guangfeng Zhao, Guijun Yan, Jie Cheng et al.

 
 

Chemotherapy treatment in women can frequently cause damage to the ovaries, which may lead to primary ovarian insufficiency (POI). In this study, we assessed the preventative …

 
 
 
 
 
 

Selective and contagious prosocial resource donation in capuchin monkeys, chimpanzees and humans

 
 

Nicolas Claidière, Andrew Whiten, Mary C. Mareno et al.

 
 

Prosocial acts benefitting others are widespread amongst humans. By contrast, chimpanzees have failed to demonstrate such a disposition in several studies, leading some authors …

 
 
 
 
 
 

Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing

 
 

Rebecca E. Lane, Darren Korbie, Will Anderson et al.

 
 

Exosomes are vesicles which have garnered interest due to their diagnostic and therapeutic potential. Isolation of pure yields of exosomes from complex biological fluids whilst …

 
 
 
 
 
 

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

 
 

Guy Griebel, Philippe Pichat, Sandra Beeské et al.

 
 

Monoacylglycerol lipase (MAGL) represents a primary degradation enzyme of the endogenous cannabinoid (eCB), 2-arachidonoyglycerol (2-AG). This study reports a potent covalent …

 
 
 
 
 
 

MicroRNA-574-3p, identified by microRNA library-based functional screening, modulates tamoxifen response in breast cancer

 
 

T. Ujihira, K. Ikeda, T. Suzuki et al.

 
 

Most primary breast cancers express estrogen receptor α and can be treated via endocrine therapy using anti-estrogens such as tamoxifen; however, acquired endocrine resistance is …

 
 
 
 
 
 

Role of indigenous iron in improving sludge dewaterability through peroxidation

 
 

Xu Zhou, Guangming Jiang, Qilin Wang et al.

 
 

Improvement of sludge dewaterability is important for reducing the total costs for the treatment and disposal of sludge in wastewater treatment plants. In this study, we …

 
 
 
 
 
 

Predicting learning plateau of working memory from whole-brain intrinsic network connectivity patterns

 
 

Masahiro Yamashita, Mitsuo Kawato, Hiroshi Imamizu

 
 

Individual learning performance of cognitive function is related to functional connections within ‘task-activated’ regions where activities increase during the corresponding …

 
 
 
 
 
 

A controllable on-off strategy for the reproductive containment of fish

 
 

Yunsheng Zhang, Ji Chen, Xiaojuan Cui et al.

 
 

A major impediment to the commercialization and cultivation of transgenic fish is the potential ecological risks they pose to natural environments: a problem that could be solved …

 
 
 
 
 
 

MLST-based inference of genetic diversity and population structure of clinical Klebsiella pneumoniae, China

 
 

Chenyi Guo, Xianwei Yang, Yarong Wu et al.

 
 

Multilocus sequence typing was applied to a collection of 327 clinical isolates of Klebsiella pneumoniae from China, which was proven to be a good representative of the global …

 
 
 
 
 
 

Limb-bud and Heart (LBH) Functions as a Tumor Suppressor of Nasopharyngeal Carcinoma by Inducing G1/S Cell Cycle Arrest

 
 

Qicai Liu, Xiaoying Guan, Jingli Lv et al.

 
 

Epstein–Barr virus-encoded latent membrane protein-1 (LMP1) plays a fundamental role in the malignant transformation of nasopharyngeal carcinoma (NPC), although the mechanism is …

 
 
 
 
 
 

Cdc48-independent proteasomal degradation coincides with a reduced need for ubiquitylation

 
 

Daniela Gödderz, Christian Heinen, Francesco P. Marchese et al.

 
 

Ubiquitin fusion degradation (UFD) substrates are delivered at the proteasome by a handover mechanism involving the ubiquitin-selective chaperone Cdc48 and the ubiquitin shuttle …

 
 
 
 
 
 

Development and Validation of A 48-Target Analytical Method for High-throughput Monitoring of Genetically Modified Organisms

 
 

Xiaofei Li, Yuhua Wu, Jun Li et al.

 
 

The rapid increase in the number of genetically modified (GM) varieties has led to a demand for high-throughput methods to detect genetically modified organisms (GMOs). We …

 
 
 
 
 
 

A Pliable Electroporation Patch (ep-Patch) for Efficient Delivery of Nucleic Acid Molecules into Animal Tissues with Irregular Surface Shapes

 
 

Zewen Wei, Yuanyu Huang, Deyao Zhao et al.

 
 

Delivery of nucleic acids into animal tissues by electroporation is an appealing approach for various types of gene therapy, but efficiency of existing methodsis not …

 
 
 
 
 
 

Effects of weight loss via high fat vs. low fat alternate day fasting diets on free fatty acid profiles

 
 

Krista A. Varady, Vi T. Dam, Monica C. Klempel et al.

 
 

Cardiovascular disease risk is associated with excess body weight and elevated plasma free fatty acid (FFA) concentrations. This study examines how an alternate-day fasting (ADF) …

 
 
 
 
 
 

Interlayer Water Regulates the Bio-nano Interface of a β-sheet Protein stacking on Graphene

 
 

Wenping Lv, Guiju Xu, Hongyan Zhang et al.

 
 

Using molecular dynamics simulations, we investigated an integrated bio-nano interface consisting of a β-sheet protein stacked onto graphene. We found that the stacking assembly …

 
 
 
 
 
 

Cave spiders choose optimal environmental factors with respect to the generated entropy when laying their cocoon

 
 

Eliodoro Chiavazzo, Marco Isaia, Stefano Mammola et al.

 
 

The choice of a suitable area to spiders where to lay eggs is promoted in terms of Darwinian fitness. Despite its importance, the underlying factors behind this key decision are …

 
 
 
 
 
 

Characterization of a Novel Reassortant Influenza A Virus (H2N2) from a Domestic Duck in Eastern China

 
 

Mai-Juan Ma, Xiao-Xian Yang, Yan-Hua Qian et al.

 
 

While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt …

 
 
 
 
 
 

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

 
 

Katsuhiko Warita, Tomoko Warita, Colin H. Beckwitt et al.

 
 

The cholesterol reducing drugs, statins, exhibit anti-tumor effects against cancer stem cells and various cancer cell lines, exert potent additivity or synergy with existing …

 
 
 
 
 
 

Social networks in primates: smart and tolerant species have more efficient networks

 
 

Cristian Pasquaretta, Marine Levé, Nicolas Claidière et al.

 
 

Network optimality has been described in genes, proteins and human communicative networks. In the latter, optimality leads to the efficient transmission of information with a …

 
 
 
 
 
 

Insulin-producing cells from embryonic stem cells rescues hyperglycemia via intra-spleen migration

 
 

Meng Ren, Changzhen Shang, Xiaomei Zhong et al.

 
 

Implantation of embryonic stem cells (ESC)-derived insulin-producing cells has been extensively investigated for treatment of diabetes in animal models. However, the in vivo …

 
 
 
 
 
 

Asymmetric parental genome engineering by Cas9 during mouse meiotic exit

 
 

Toru Suzuki, Maki Asami, Anthony C. F. Perry

 
 

Mammalian genomes can be edited by injecting pronuclear embryos with Cas9 cRNA and guide RNA (gRNA) but it is unknown whether editing can also occur during the onset of embryonic …

 
 
 
 
 
 

Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice

 
 

Lillia V. Ryazanova, Zhixian Hu, Sayuri Suzuki et al.

 
 

TRPM7 is an unusual bi-functional protein containing an ion channel covalently linked to a protein kinase domain. TRPM7 is implicated in regulating cellular and systemic …

 
 
 
 
 
 

Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer

 
 

Jun Ho Yi, In-Gu Do, Jiryeon Jang et al.

 
 

To investigate the prognostic role of the estrogen receptor (ER) in gastric cancer (GC) patients, tumor tissues from 932 patients with advanced GC were assessed for ER expression …

 
 
 
 
 
 

Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration

 
 

Ke Wang, Jia Xiao, Bo Peng et al.

 
 

Retinitis pigmentosa (RP) is a heterogeneous group of inherited disorders caused by mutations in a variety of genes that are mostly expressed by rod cells, which results in …

 
 
 
 
 
 

Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate

 
 

P. Edward Purdue, Tania N. Crotti, Zhenxin Shen et al.

 
 

As the only cells capable of efficiently resorbing bone, osteoclasts are central mediators of both normal bone remodeling and pathologies associates with excessive bone …

 
 
 
 
 
 

Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling

 
 

S. Tsukamoto, T. Mizuta, M. Fujimoto et al.

 
 

Smad1, Smad5 and Smad9 (also known as Smad8) are activated by phosphorylation by bone morphogenetic protein (BMP)-bound type I receptor kinases. We examined the role of Smad1, …

 
 
 
 
 
 

G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

 
 

Matthias R. Meyer, Natalie C. Fredette, Tamara A. Howard et al.

 
 

Coronary atherosclerosis and myocardial infarction in postmenopausal women have been linked to inflammation and reduced nitric oxide (NO) formation. Natural estrogen exerts …

 
 
 
 
 
 

Cardiac endothelial cell-derived exosomes induce specific regulatory B cells

 
 

Jiangping Song, Xiao Chen, Mangyuan Wang et al.

 
 

The mechanism of immune tolerance is to be further understood. The present study aims to investigate the role of the Cardiac endothelial cell (CEC)-derived exosomes in the …

 
 
 
 
 
 

The awareness, perceptions and experiences of primary open angle glaucoma patients in Lagos Nigeria

 
 

Chigozie Anuli Mbadugha, Adeola Olukorede Onakoya

 
 

The awareness, perceptions and experiences of Nigerian Primary Open Angle Glaucoma (POAG) patients were assessed using a hospital based cross-sectional study design. One hundred …

 
 
 
 
 
 

A Simplified Method to Recover Urinary Vesicles for Clinical Applications, and Sample Banking

 
 

Luca Musante, Dorota Tataruch, Dongfeng Gu et al.

 
 

Urinary extracellular vesicles provide a novel source for valuable biomarkers for kidney and urogenital diseases: Current isolation protocols include laborious, sequential …

 
 
 
 
 
 

Induced apoptosis in melanocytes cancer cell and oxidation in biomolecules through deuterium oxide generated from atmospheric pressure non-thermal plasma jet

 
 

Naresh Kumar, Pankaj Attri, Dharmendra Kumar Yadav et al.

 
 

Recently, atmospheric-pressure non-thermal plasma-jets (APPJ) are being for the cancer treatment. However, APPJ still has drawbacks such as efficiency and rise in temperature …

 
 
 
 
 
 
   
 
 
Chemical Sciences top
 
 
 
 
 
 
 

Microfluidic-SANS: flow processing of complex fluids

 
 

Carlos G. Lopez, Takaichi Watanabe, Anne Martel et al.

 
 

Understanding and engineering the flow-response of complex and non-Newtonian fluids at a molecular level is a key challenge for their practical utilisation. Here we demonstrate …

 
 
 
 
 
 

Molecularly imprinted polymer decorated nanoporous gold for highly selective and sensitive electrochemical sensors

 
 

Yingchun Li, Yuan Liu, Jie Liu et al.

 
 

Electrochemical nanosensors based on nanoporous gold leaf (NPGL) and molecularly imprinted polymer (MIP) are developed for pharmaceutical analysis by using metronidazole (MNZ) as …

 
 
 
 
 
 

Hollow carbon nanospheres/silicon/alumina core-shell film as an anode for lithium-ion batteries

 
 

Bing Li, Fei Yao, Jung Jun Bae et al.

 
 

Hollow carbon nanospheres/silicon/alumina (CNS/Si/Al2O3) core-shell films obtained by the deposition of Si and Al2O3 on hollow CNS interconnected films are used as the anode …

 
 
 
 
 
 

One-dimensional manganese-cobalt oxide nanofibres as bi-functional cathode catalysts for rechargeable metal-air batteries

 
 

Kyu-Nam Jung, Soo Min Hwang, Min-Sik Park et al.

 
 

Rechargeable metal-air batteries are considered a promising energy storage solution owing to their high theoretical energy density. The major obstacles to realising this …

 
 
 
 
 
 

Electrochemical performance and carbon deposition resistance of M-BaZr0.1Ce0.7Y0.1Yb0.1O3-δ (M=Pd, Cu, Ni or NiCu) anodes for solid oxide fuel cells

 
 

Meng Li, Bin Hua, Jian Pu et al.

 
 

Pd-, Cu-, Ni- and NiCu-BaZr0.1Ce0.7Y0.1Yb0.1O3-δ anodes, designated as M-BZCYYb, were prepared by impregnating M-containing solution into BZCYYb scaffold, and investigated in the …

 
 
 
 
 
 

Graphene-Co3O4 nanocomposite as electrocatalyst with high performance for oxygen evolution reaction

 
 

Yufei Zhao, Shuangqiang Chen, Bing Sun et al.

 
 

Graphene-Co3O4 composite with a unique sandwich-architecture was successfully synthesized and applied as an efficient electrocatalyst for oxygen evolution reaction. Field …

 
 
 
 
 
 

Energy Efficient Glazing for Adaptive Solar Control Fabricated with Photothermotropic Hydrogels Containing Graphene Oxide

 
 

Dowan Kim, Eunsu Lee, Heon Sang Lee et al.

 
 

Glazing for adaptive solar control is the most promising for energy efficient development, because the use of this technology in buildings can be expected to significantly impact …

 
 
 
 
 
 

Trapping of microwave radiation in hollow polypyrrole microsphere through enhanced internal reflection: A novel approach

 
 

Ritwik Panigrahi, Suneel K. Srivastava

 
 

In present work, spherical core (polystyrene, PS)/shell (polypyrrole, PPy) has been synthesized via in situ chemical oxidative copolymerization of pyrrole (Py) on the surface of …

 
 
 
 
 
 

Synthesis and Characterization of Water-Soluble Polythiophene Derivatives for Cell Imaging

 
 

Fengyan Wang, Meng Li, Bing Wang et al.

 
 

In this work, four water-soluble polythiophene derivatives (PT, PT-DDA, PT-ADA, and PT-ADA-PPR) with different pendant moieties were synthesized via oxidative copolymerization by …

 
 
 
 
 
 

A Strategy for Fabricating Porous PdNi@Pt Core-shell Nanostructures and Their Enhanced Activity and Durability for the Methanol Electrooxidation

 
 

Xinyu Liu, Guangrui Xu, Yu Chen et al.

 
 

Three-dimensionally (3D) porous morphology of nanostructures can effectively improve their electrocatalytic activity and durability for various electrochemical reactions owing to …

 
 
 
 
 
 

Interlayer Water Regulates the Bio-nano Interface of a β-sheet Protein stacking on Graphene

 
 

Wenping Lv, Guiju Xu, Hongyan Zhang et al.

 
 

Using molecular dynamics simulations, we investigated an integrated bio-nano interface consisting of a β-sheet protein stacked onto graphene. We found that the stacking assembly …

 
 
 
 
 
 

A lithium-ion sulfur battery using a polymer, polysulfide-added membrane

 
 

Marco Agostini, Jusef Hassoun

 
 

In this paper we report the performances of a lithium-ion sulfur battery characterized by a polymer configuration. The cell, based on a sulfur-carbon cathode, a Li-Sn-C …

 
 
 
 
 
 

Laser Induced Breakdown Spectroscopy Based on Single Beam Splitting and Geometric Configuration for Effective Signal Enhancement

 
 

Guang Yang, Qingyu Lin, Yu Ding et al.

 
 

A new laser induced breakdown spectroscopy (LIBS) based on single-beam-splitting (SBS) and proper optical geometric configuration has been initially explored in this work for …

 
 
 
 
 
 

One-pot synthesis of core-shell Cu@SiO2 nanospheres and their catalysis for hydrolytic dehydrogenation of ammonia borane and hydrazine borane

 
 

Qilu Yao, Zhang-Hui Lu, Zhujun Zhang et al.

 
 

Ultrafine copper nanoparticles (Cu NPs) within porous silica nanospheres (Cu@SiO2) were prepared via a simple one-pot synthetic route in a reverse micelle system and …

 
 
 
 
 
 
   
 
 
Physical Sciences top
 
 
 
 
 
 
 

Hybrid optical fiber add-drop filter based on wavelength dependent light coupling between micro/nano fiber ring and side-polished fiber

 
 

Jianhui Yu, Shaoshen Jin, Qingsong Wei et al.

 
 

In this paper, we report our experimental study on directly coupling a micro/nano fiber (MNOF) ring with a side-polished fiber(SPF). As a result of the study, the behavior of an …

 
 
 
 
 
 

Microfluidic-SANS: flow processing of complex fluids

 
 

Carlos G. Lopez, Takaichi Watanabe, Anne Martel et al.

 
 

Understanding and engineering the flow-response of complex and non-Newtonian fluids at a molecular level is a key challenge for their practical utilisation. Here we demonstrate …

 
 
 
 
 
 

Strong-field plasmonic photoemission in the mid-IR at <1 GW/cm2 intensity

 
 

S. M. Teichmann, P. Rácz, M. F. Ciappina et al.

 
 

We investigated nonlinear photoemission from plasmonic films with femtosecond, mid-infrared pulses at 3.1 μm wavelength. Transition between regimes of multi-photon-induced and …

 
 
 
 
 
 

Synergy of elastic and inelastic energy loss on ion track formation in SrTiO3

 
 

William J. Weber, Eva Zarkadoula, Olli H. Pakarinen et al.

 
 

While the interaction of energetic ions with solids is well known to result in inelastic energy loss to electrons and elastic energy loss to atomic nuclei in the solid, the …

 
 
 
 
 
 

Pressure control of magnetic clusters in strongly inhomogeneous ferromagnetic chalcopyrites

 
 

Temirlan R. Arslanov, Akhmedbek Yu. Mollaev, Ibragimkhan K. Kamilov et al.

 
 

Room-temperature ferromagnetism in Mn-doped chalcopyrites is a desire aspect when applying those materials to spin electronics. However, dominance of high Curie-temperatures due …

 
 
 
 
 
 

Organic-on-silicon complementary metal–oxide–semiconductor colour image sensors

 
 

Seon-Jeong Lim, Dong-Seok Leem, Kyung-Bae Park et al.

 
 

Complementary metal–oxide–semiconductor (CMOS) colour image sensors are representative examples of light-detection devices. To achieve extremely high resolutions, the pixel sizes …

 
 
 
 
 
 

Improved All-Carbon Spintronic Device Design

 
 

Zachary Bullard, Eduardo Costa Girão, Jonathan R. Owens et al.

 
 

The discovery of magnetism in carbon structures containing zigzag edges has stimulated new directions in the development and design of spintronic devices. However, many of the …

 
 
 
 
 
 

Crystalline structures of polymeric hydrocarbon with 3,4-fold helical chains

 
 

Chao-Sheng Lian, Han-Dong Li, Jian-Tao Wang

 
 

Molecular hydrocarbons are well-known to polymerize under pressure to form covalently bonded frameworks. Here we predict by ab initio calculations two distinct three-dimensional …

 
 
 
 
 
 

Giant electrocaloric effect in ferroelectric nanotubes near room temperature

 
 

Man Liu, Jie Wang

 
 

Ferroelectric perovskite oxides possess large electrocaloric effect, but only at high temperature, which limits their potential as next generation solid state cooling devices. …

 
 
 
 
 
 

Hexagonal-like Nb2O5 Nanoplates-Based Photodetectors and Photocatalyst with High Performances

 
 

Hui Liu, Nan Gao, Meiyong Liao et al.

 
 

Ultraviolet (UV) photodetectors are important tools in the fields of optical imaging, environmental monitoring, and air and water sterilization, as well as flame sensing and …

 
 
 
 
 
 

Growing perovskite into polymers for easy-processable optoelectronic devices

 
 

Sofia Masi, Silvia Colella, Andrea Listorti et al.

 
 

Here we conceive an innovative nanocomposite to endow hybrid perovskites with the easy processability of polymers, providing a tool to control film quality and material …

 
 
 
 
 
 

Molecularly imprinted polymer decorated nanoporous gold for highly selective and sensitive electrochemical sensors

 
 

Yingchun Li, Yuan Liu, Jie Liu et al.

 
 

Electrochemical nanosensors based on nanoporous gold leaf (NPGL) and molecularly imprinted polymer (MIP) are developed for pharmaceutical analysis by using metronidazole (MNZ) as …

 
 
 
 
 
 

Strain-Induced Extrinsic High-Temperature Ferromagnetism in the Fe-Doped Hexagonal Barium Titanate

 
 

A. Zorko, M. Pregelj, M. Gomilšek et al.

 
 

Diluted magnetic semiconductors possessing intrinsic static magnetism at high temperatures represent a promising class of multifunctional materials with high application …

 
 
 
 
 
 

Characterization of efficiency-limiting resistance losses in monolithically integrated Cu(In,Ga)Se2 solar modules

 
 

Ju-Heon Yoon, Jong-Keuk Park, Won Mok Kim et al.

 
 

The cell-to-module efficiency gap in Cu(In,Ga)Se2 (CIGS) monolithically integrated solar modules is enhanced by contact resistance between the Al-doped ZnO (AZO) and Mo back …

 
 
 
 
 
 

Electrotunable Lubricity with Ionic Liquid Nanoscale Films

 
 

O. Y. Fajardo, F. Bresme, A. A. Kornyshev et al.

 
 

One of the main challenges in tribology is finding the way for an in situ control of friction without changing the lubricant. One of the ways for such control is via the …

 
 
 
 
 
 

A Highly Efficient Approach to Protein Interactome Mapping Based on Collaborative Filtering Framework

 
 

Xin Luo, Zhuhong You, Mengchu Zhou et al.

 
 

The comprehensive mapping of protein-protein interactions (PPIs) is highly desired for one to gain deep insights into both fundamental cell biology processes and the pathology of …

 
 
 
 
 
 

Decreased deformability of lymphocytes in chronic lymphocytic leukemia

 
 

Yi Zheng, Jun Wen, John Nguyen et al.

 
 

This paper reports the first study of stiffness/deformability changes of lymphocytes in chronic lymphocytic leukemia (CLL) patients, demonstrating that at the single cell level, …

 
 
 
 
 
 

Unforeseen high temperature and humidity stability of FeCl3 intercalated few layer graphene

 
 

Dominique Joseph Wehenkel, Thomas Hardisty Bointon, Tim Booth et al.

 
 

We present the first systematic study of the stability of the structure and electrical properties of FeCl3 intercalated few-layer graphene to high levels of humidity and high …

 
 
 
 
 
 

Luminescence signature of free exciton dissociation and liberated electron transfer across the junction of graphene/GaN hybrid structure

 
 

Jun Wang, Changcheng Zheng, Jiqiang Ning et al.

 
 

Large-area graphene grown on Cu foil with chemical vapor deposition was transferred onto intentionally undoped GaN epilayer to form a graphene/GaN Schottky junction. Optical …

 
 
 
 
 
 

Superior intrinsic thermoelectric performance with zT of 1.8 in single-crystal and melt-quenched highly dense Cu2-xSe bulks

 
 

Lan-ling Zhao, Xiao-lin Wang, Ji-yang Wang et al.

 
 

Practical applications of the high temperature thermoelectric materials developed so far are partially obstructed by the costly and complicated fabrication process. In this work, …

 
 
 
 
 
 

Universal Order Parameters and Quantum Phase Transitions: A Finite-Size Approach

 
 

Qian-Qian Shi, Huan-Qiang Zhou, Murray T. Batchelor

 
 

We propose a method to construct universal order parameters for quantum phase transitions in many-body lattice systems. The method exploits the H-orthogonality of a few …

 
 
 
 
 
 

Thermally reduced kaolin-graphene oxide nanocomposites for gas sensing

 
 

Renyun Zhang, Viviane Alecrim, Magnus Hummelgård et al.

 
 

Highly sensitive graphene-based gas sensors can be made using large-area single layer graphene, but the cost of large-area pure graphene is high, making the simpler reduced …

 
 
 
 
 
 

Inter-cluster distance dependence of electrical conduction in nanocluster assembled films of silver: a new paradigm for design of nanostructures

 
 

Chandrahas Bansal, S. G. Praveen, J. T. T. Kumaran et al.

 
 

The transport properties of films assembled from metal nanoclusters can be significantly different from the metals in their bulk or thin film forms due to quantum confinement …

 
 
 
 
 
 

Artificial magnetic field induced by an evanescent wave

 
 

Małgorzata Mochol, Krzysztof Sacha

 
 

Cold atomic gases are perfect laboratories for realization of quantum simulators. In order to simulate solid state systems in the presence of magnetic fields special effort has …

 
 
 
 
 
 

A growth model for directed complex networks with power-law shape in the out-degree distribution

 
 

J. Esquivel-Gómez, E. Stevens-Navarro, U. Pineda-Rico et al.

 
 

Many growth models have been published to model the behavior of real complex networks. These models are able to reproduce several of the topological properties of such networks. …

 
 
 
 
 
 

Enhanced multiple vibrational resonances by Na+ and K+ dynamics in a neuron model

 
 

Xing-Xing Wu, Chenggui Yao, Jianwei Shuai

 
 

Some neuronal receptors perceive external input in the form of hybrid periodic signals. The signal detection may be based on the mechanism of vibrational resonance, in which a …

 
 
 
 
 
 

Rapid Synthesis of Monodisperse Au Nanospheres through a Laser Irradiation -Induced Shape Conversion, Self-Assembly and Their Electromagnetic Coupling SERS Enhancement

 
 

Dilong Liu, Cuncheng Li, Fei Zhou et al.

 
 

We develop a facile and effective strategy to prepare monodispersed Au spherical nanoparticles by two steps. Large-scale monocrystalline Au nanooctahedra with uniform size were …

 
 
 
 
 
 

Rapid assessment of nonlinear optical propagation effects in dielectrics

 
 

J. del Hoyo, A. Ruiz de la Cruz, E. Grace et al.

 
 

Ultrafast laser processing applications need fast approaches to assess the nonlinear propagation of the laser beam in order to predict the optimal range of processing parameters …

 
 
 
 
 
 

A proposal for the experimental detection of CSL induced random walk

 
 

Sayantani Bera, Bhawna Motwani, Tejinder P. Singh et al.

 
 

Continuous Spontaneous Localization (CSL) is one possible explanation for dynamically induced collapse of the wave-function during a quantum measurement. The collapse is mediated …

 
 
 
 
 
 

Probing dynamics and pinning of single vortices in superconductors at nanometer scales

 
 

L. Embon, Y. Anahory, A. Suhov et al.

 
 

The dynamics of quantized magnetic vortices and their pinning by materials defects determine electromagnetic properties of superconductors, particularly their ability to carry …

 
 
 
 
 
 

Hollow carbon nanospheres/silicon/alumina core-shell film as an anode for lithium-ion batteries

 
 

Bing Li, Fei Yao, Jung Jun Bae et al.

 
 

Hollow carbon nanospheres/silicon/alumina (CNS/Si/Al2O3) core-shell films obtained by the deposition of Si and Al2O3 on hollow CNS interconnected films are used as the anode …

 
 
 
 
 
 

Artificial tektites: an experimental technique for capturing the shapes of spinning drops

 
 

Kyle A. Baldwin, Samuel L. Butler, Richard J. A. Hill

 
 

Determining the shapes of a rotating liquid droplet bound by surface tension is an archetypal problem in the study of the equilibrium shapes of a spinning and charged droplet, a …

 
 
 
 
 
 

Plectoneme tip bubbles: Coupled denaturation and writhing in supercoiled DNA

 
 

Christian Matek, Thomas E. Ouldridge, Jonathan P. K. Doye et al.

 
 

We predict a novel conformational regime for DNA, where denaturation bubbles form at the tips of plectonemes, and study its properties using coarse-grained simulations. For …

 
 
 
 
 
 

One-dimensional manganese-cobalt oxide nanofibres as bi-functional cathode catalysts for rechargeable metal-air batteries

 
 

Kyu-Nam Jung, Soo Min Hwang, Min-Sik Park et al.

 
 

Rechargeable metal-air batteries are considered a promising energy storage solution owing to their high theoretical energy density. The major obstacles to realising this …

 
 
 
 
 
 

Electrochemical performance and carbon deposition resistance of M-BaZr0.1Ce0.7Y0.1Yb0.1O3-δ (M=Pd, Cu, Ni or NiCu) anodes for solid oxide fuel cells

 
 

Meng Li, Bin Hua, Jian Pu et al.

 
 

Pd-, Cu-, Ni- and NiCu-BaZr0.1Ce0.7Y0.1Yb0.1O3-δ anodes, designated as M-BZCYYb, were prepared by impregnating M-containing solution into BZCYYb scaffold, and investigated in the …

 
 
 
 
 
 

Polarization response of nanowires à la carte

 
 

Alberto Casadei, Esther Alarcon Llado, Francesca Amaduzzi et al.

 
 

Thanks to their special interaction with light, semiconductor nanowires have opened new avenues in photonics, quantum optics and solar energy harvesting. One of the major …

 
 
 
 
 
 

Room-Temperature Single-photon level Memory for Polarization States

 
 

Connor Kupchak, Thomas Mittiga, Bertus Jordaan et al.

 
 

An optical quantum memory is a stationary device that is capable of storing and recreating photonic qubits with a higher fidelity than any classical device. Thus far, these two …

 
 
 
 
 
 

Skyrmion-skyrmion and skyrmion-edge repulsions in skyrmion-based racetrack memory

 
 

Xichao Zhang, G. P. Zhao, Hans Fangohr et al.

 
 

Magnetic skyrmions are promising for building next-generation magnetic memories and spintronic devices due to their stability, small size and the extremely low currents needed to …

 
 
 
 
 
 

Following the dynamics of matter with femtosecond precision using the X-ray streaking method

 
 

C. David, P. Karvinen, M. Sikorski et al.

 
 

X-ray Free Electron Lasers (FELs) can produce extremely intense and very short pulses, down to below 10 femtoseconds (fs). Among the key applications are ultrafast time-resolved …

 
 
 
 
 
 

Graphene-Co3O4 nanocomposite as electrocatalyst with high performance for oxygen evolution reaction

 
 

Yufei Zhao, Shuangqiang Chen, Bing Sun et al.

 
 

Graphene-Co3O4 composite with a unique sandwich-architecture was successfully synthesized and applied as an efficient electrocatalyst for oxygen evolution reaction. Field …

 
 
 
 
 
 

Energy Efficient Glazing for Adaptive Solar Control Fabricated with Photothermotropic Hydrogels Containing Graphene Oxide

 
 

Dowan Kim, Eunsu Lee, Heon Sang Lee et al.

 
 

Glazing for adaptive solar control is the most promising for energy efficient development, because the use of this technology in buildings can be expected to significantly impact …

 
 
 
 
 
 

Preparation and Upconversion Emission Modification of Crystalline Colloidal Arrays and Rare Earth Fluoride Microcrystal Composites

 
 

Jiayan Liao, Zhengwen Yang, Jinbo Sun et al.

 
 

In this paper, highly ordered crystalline colloidal arrays containing rare earth fluoride microcrystals were fabricated. The upconversion emission property of rare earth fluoride …

 
 
 
 
 
 

Orientation in multi-layer chitosan hydrogel: morphology, mechanism, and design principle

 
 

Jingyi Nie, Wentao Lu, Jianjun Ma et al.

 
 

Hydrogels with organized structure have attracted remarkable attentions for bio-related applications. Among the preparation of hierarchical hydrogel materials, fabrication of …

 
 
 
 
 
 

Trapping of microwave radiation in hollow polypyrrole microsphere through enhanced internal reflection: A novel approach

 
 

Ritwik Panigrahi, Suneel K. Srivastava

 
 

In present work, spherical core (polystyrene, PS)/shell (polypyrrole, PPy) has been synthesized via in situ chemical oxidative copolymerization of pyrrole (Py) on the surface of …

 
 
 
 
 
 

High-Pressure Orthorhombic Ferromagnesite as a Potential Deep-Mantle Carbon Carrier

 
 

Jin Liu, Jung-Fu Lin, Vitali B. Prakapenka

 
 

Knowledge of the physical and chemical properties of candidate deep-carbon carriers such as ferromagnesite [(Mg,Fe)CO3] at high pressure and temperature of the deep mantle is …

 
 
 
 
 
 

Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing

 
 

Rebecca E. Lane, Darren Korbie, Will Anderson et al.

 
 

Exosomes are vesicles which have garnered interest due to their diagnostic and therapeutic potential. Isolation of pure yields of exosomes from complex biological fluids whilst …

 
 
 
 
 
 

Ultra-low percolation threshold in ferrite-metal cofired ceramics brings both high permeability and high permittivity

 
 

Liang Wang, Yang Bai, Xuefei Lu et al.

 
 

High permeability and high permittivity are hard to be achieved simultaneously, either in single-phased materials or in composite materials, such as ferrite-ferroelectric ceramic …

 
 
 
 
 
 

Synthesis and Characterization of Water-Soluble Polythiophene Derivatives for Cell Imaging

 
 

Fengyan Wang, Meng Li, Bing Wang et al.

 
 

In this work, four water-soluble polythiophene derivatives (PT, PT-DDA, PT-ADA, and PT-ADA-PPR) with different pendant moieties were synthesized via oxidative copolymerization by …

 
 
 
 
 
 

A Strategy for Fabricating Porous PdNi@Pt Core-shell Nanostructures and Their Enhanced Activity and Durability for the Methanol Electrooxidation

 
 

Xinyu Liu, Guangrui Xu, Yu Chen et al.

 
 

Three-dimensionally (3D) porous morphology of nanostructures can effectively improve their electrocatalytic activity and durability for various electrochemical reactions owing to …

 
 
 
 
 
 

Simulation of the ground states of spin rings with cavity-assisted neutral atoms

 
 

Peng Xue, Xiang Zhan, Zhihao Bian

 
 

Quantum phase transitions occur when the ground state of a Hamiltonian undergoes qualitative changes with a control parameter changing. In this paper we consider a particular …

 
 
 
 
 
 

Laser Induced Breakdown Spectroscopy Based on Single Beam Splitting and Geometric Configuration for Effective Signal Enhancement

 
 

Guang Yang, Qingyu Lin, Yu Ding et al.

 
 

A new laser induced breakdown spectroscopy (LIBS) based on single-beam-splitting (SBS) and proper optical geometric configuration has been initially explored in this work for …

 
 
 
 
 
 

Interlayer Water Regulates the Bio-nano Interface of a β-sheet Protein stacking on Graphene

 
 

Wenping Lv, Guiju Xu, Hongyan Zhang et al.

 
 

Using molecular dynamics simulations, we investigated an integrated bio-nano interface consisting of a β-sheet protein stacked onto graphene. We found that the stacking assembly …

 
 
 
 
 
 

A lithium-ion sulfur battery using a polymer, polysulfide-added membrane

 
 

Marco Agostini, Jusef Hassoun

 
 

In this paper we report the performances of a lithium-ion sulfur battery characterized by a polymer configuration. The cell, based on a sulfur-carbon cathode, a Li-Sn-C …

 
 
 
 
 
 

Dielectric tube waveguides with absorptive cladding for broadband, low-dispersion and low loss THz guiding

 
 

Hualong Bao, Kristian Nielsen, Ole Bang et al.

 
 

Research on terahertz waveguides is experiencing a tremendous growth due to their importance for compact and robust THz systems. However, designing compact, broadband, …

 
 
 
 
 
 

High-sensitivity strain sensor based on in-fiber rectangular air bubble

 
 

Shen Liu, Kaiming Yang, Yiping Wang et al.

 
 

We demonstrated a unique rectangular air bubble by means of splicing two sections of standard single mode fibers together and tapering the splicing joint. Such an air bubble can …

 
 
 
 
 
 

Porphyrin conjugated SiC/SiOx nanowires for X-ray-excited photodynamic therapy

 
 

F. Rossi, E. Bedogni, F. Bigi et al.

 
 

The development of innovative nanosystems opens new perspectives for multidisciplinary applications at the frontier between materials science and nanomedicine. Here we present a …

 
 
 
 
 
 

Long-range Cooper pair splitter with high entanglement production rate

 
 

Wei Chen, D. N. Shi, D. Y. Xing

 
 

Cooper pairs in the superconductor are a natural source of spin entanglement. The existing proposals of the Cooper pair splitter can only realize a low efficiency of entanglement …

 
 
 
 
 
 

Cave spiders choose optimal environmental factors with respect to the generated entropy when laying their cocoon

 
 

Eliodoro Chiavazzo, Marco Isaia, Stefano Mammola et al.

 
 

The choice of a suitable area to spiders where to lay eggs is promoted in terms of Darwinian fitness. Despite its importance, the underlying factors behind this key decision are …

 
 
 
 
 
 

One-pot synthesis of core-shell Cu@SiO2 nanospheres and their catalysis for hydrolytic dehydrogenation of ammonia borane and hydrazine borane

 
 

Qilu Yao, Zhang-Hui Lu, Zhujun Zhang et al.

 
 

Ultrafine copper nanoparticles (Cu NPs) within porous silica nanospheres (Cu@SiO2) were prepared via a simple one-pot synthetic route in a reverse micelle system and …

 
 
 
 
 
 

Magnetic structure and Magnetic transport Properties of Graphene Nanoribbons With Sawtooth Zigzag Edges

 
 

D. Wang, Z. Zhang, Z. Zhu et al.

 
 

The magnetic structure and magnetic transport properties of hydrogen-passivated sawtooth zigzag-edge graphene nanoribbons (STGNRs) are investigated theoretically. It is found …

 
 
 
 
 
 

In-situ and tunable nitrogen-doping of MoS2 nanosheets

 
 

Si Qin, Weiwei Lei, Dan Liu et al.

 
 

Molybdenum disulfide (MoS2) nanosheets have unique physical and chemical properties, which make it a perfect candidate for next generation electronic and energy storage …

 
 
 
 
 
 

An error-resilient non-volatile magneto-elastic universal logic gate with ultralow energy-delay product

 
 

Ayan K. Biswas, Jayasimha Atulasimha, Supriyo Bandyopadhyay

 
 

A long-standing goal of computer technology is to process and store digital information with the same device in order to implement new architectures. One way to accomplish this …

 
 
 
 
 
 

Influence of Interconfigurational Electronic States on Fe, Co, Ni-Silicene Materials Selection for Spintronics

 
 

Harman Johll, Michael Dao Kang Lee, Sean Peng Nam Ng et al.

 
 

Growth through controlled adsorption of ferromagnetic elements such as Fe, Co and Ni on two-dimensional silicene provides an alternative route for silicon-based spintronics. …

 
 
 
 
 
 

Hydrogen bonds in Al2O3 as dissipative two-level systems in superconducting qubits

 
 

Luke Gordon, Hazem Abu-Farsakh, Anderson Janotti et al.

 
 

Dissipative two-level systems (TLS) have been a long-standing problem in glassy solids over the last fifty years, and have recently gained new relevance as sources of decoherence …

 
 
 
 
 
 

Induced apoptosis in melanocytes cancer cell and oxidation in biomolecules through deuterium oxide generated from atmospheric pressure non-thermal plasma jet

 
 

Naresh Kumar, Pankaj Attri, Dharmendra Kumar Yadav et al.

 
 

Recently, atmospheric-pressure non-thermal plasma-jets (APPJ) are being for the cancer treatment. However, APPJ still has drawbacks such as efficiency and rise in temperature …

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

Growing perovskite into polymers for easy-processable optoelectronic devices

 
 

Sofia Masi, Silvia Colella, Andrea Listorti et al.

 
 

Here we conceive an innovative nanocomposite to endow hybrid perovskites with the easy processability of polymers, providing a tool to control film quality and material …

 
 
 
 
 
 

A new tool for predicting drought: An application over India

 
 

M. N. Kulkarni

 
 

This is the first attempt of application of atmospheric electricity for rainfall prediction. The atmospheric electrical columnar resistance based on the model calculations …

 
 
 
 
 
 

Artificial tektites: an experimental technique for capturing the shapes of spinning drops

 
 

Kyle A. Baldwin, Samuel L. Butler, Richard J. A. Hill

 
 

Determining the shapes of a rotating liquid droplet bound by surface tension is an archetypal problem in the study of the equilibrium shapes of a spinning and charged droplet, a …

 
 
 
 
 
 

Detailed investigation of the microbial community in foaming activated sludge reveals novel foam formers

 
 

Feng Guo, Zhi-Ping Wang, Ke Yu et al.

 
 

Foaming of activated sludge (AS) causes adverse impacts on wastewater treatment operation and hygiene. In this study, we investigated the microbial communities of foam, foaming …

 
 
 
 
 
 

High-Pressure Orthorhombic Ferromagnesite as a Potential Deep-Mantle Carbon Carrier

 
 

Jin Liu, Jung-Fu Lin, Vitali B. Prakapenka

 
 

Knowledge of the physical and chemical properties of candidate deep-carbon carriers such as ferromagnesite [(Mg,Fe)CO3] at high pressure and temperature of the deep mantle is …

 
 
 
 
 
 

Role of indigenous iron in improving sludge dewaterability through peroxidation

 
 

Xu Zhou, Guangming Jiang, Qilin Wang et al.

 
 

Improvement of sludge dewaterability is important for reducing the total costs for the treatment and disposal of sludge in wastewater treatment plants. In this study, we …

 
 
 
 
 
 
 
Health Sciences top
 
 
 
 
 
 
 

Systematic Review and Meta-analysis of the Survival Outcomes of First-line Treatment Options in High-risk Prostate Cancer

 
 

Jun H. Lei, Liang R. Liu, Qiang Wei et al.

 
 

Prostate cancer (PCa) is the most common non-dermatologic cancer in the western countries in western countries. High-risk PCa accounts for 15% of the diagnosed cases. In this …

 
 
 
 
 
 

Prevalence and genetic characteristics of Saffold cardiovirus in China from 2009 to 2012

 
 

Xiao-Ai Zhang, Qing-Bin Lu, Ying Wo et al.

 
 

The epidemiology and clinical features of the Saffold cardiovirus (SAFV) remain ambiguous. The present study was designed to systematically and intensively investigate the …

 
 
 
 
 
 

Observational Study of Effects of Saroglitazar on Glycaemic and Lipid Parameters on Indian Patients with Type 2 Diabetes

 
 

Sanjay Chatterjee, Anirban Majumder, Subir Ray

 
 

Cardiovascular risk reduction is an important issue in the management of patients with Type 2 diabetes mellitus. Peroxisome proliferator activated receptor (PPAR) agonists …

 
 
 
 
 
 

Interleukin 13-positive mast cells are increased in immunoglobulin G4-related sialadenitis

 
 

Mai Takeuchi, Kyotaro Ohno, Katsuyoshi Takata et al.

 
 

Interleukin (IL)-13 is a T helper 2 (Th2) cytokine that plays important roles in the pathogenesis of asthma. IL-13 induces hypersensitivity of the airways, increased mucous …

 
 
 
 
 
 

Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration

 
 

Fuxiang Ye, Hiroki Kaneko, Yosuke Nagasaka et al.

 
 

Choroidal neovascularization (CNV) is the main pathogenesis of age-related macular degeneration (AMD), which leads to severe vision loss in many aged patients in most advanced …

 
 
 
 
 
 

Palladin is Upregulated in Kidney Disease and Contributes to Epithelial Cell Migration After Injury

 
 

Emily H. Chang, Adil H. Gasim, Michael L. Kerber et al.

 
 

Recovery from acute kidney injury involving tubular epithelial cells requires proliferation and migration of healthy cells to the area of injury. In this study, we show that …

 
 
 
 
 
 

Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells

 
 

Jianhong Yang, Yongzhao Zhou, Xia Cheng et al.

 
 

To overcome drug resistance caused by apoptosis deficiency in patients with non-small cell lung carcinoma (NSCLC), there is a need to identify other means of triggering …

 
 
 
 
 
 

Nausea and Vomiting in Early Pregnancy and the Risk of Neural Tube Defects: a Case-Control Study

 
 

Qing-Bin Lu, Zhi-Ping Wang, Li-Jie Gao et al.

 
 

There has been considerable professional debate on the association between nausea and vomiting in early pregnancy (NVP) and neural tube defects (NTDs) risk. This study explored …

 
 
 
 
 
 

An injured tissue affects the opposite intact peritoneum during postoperative adhesion formation

 
 

Tatsuya Suzuki, Toru Kono, Hiroki Bochimoto et al.

 
 

The pathophysiology of adhesion formation needs to be clarified to reduce the adhesion-related morbidity. The epithelial characteristics of the peritoneum suggest a protective …

 
 
 
 
 
 

The Effectiveness of RECIST on Survival in Patients with NSCLC Receiving Chemotherapy with or without Target Agents as First-Line Treatment

 
 

Ting Zhou, Lie Zheng, Zhihuang Hu et al.

 
 

We analyzed the correlation between survival and antitumor effect evaluated by RECIST in advanced NSCLC patients with chemotherapy plus target therapy or not as first-line …

 
 
 
 
 
 

The occurrence and progression of outer retinal tubulation in Chinese patients after intravitreal injections of ranibizumab

 
 

Rui Hua, Limin Liu, Yuedong Hu et al.

 
 

To investigate the occurrence and progression of outer retinal tubulation (ORT) in Chinese patients after intravitreal ranibizumab injections, using spectral domain optical …

 
 
 
 
 
 

A long-term, prospective, cohort study on the performance of right ventricular pacing leads: comparison of active-fixation with passive-fixation leads

 
 

Lie Liu, Jiaojiao Tang, Hu Peng et al.

 
 

Active-fixation pacing leads allow the use of selective pacing sites. We evaluated their long-term performance versus passive-fixation leads in 199 newly implanted patients (n=…

 
 
 
 
 
 

Constitutively Active AR-V7 Plays an Essential Role in the Development and Progression of Castration-Resistant Prostate Cancer

 
 

Yuanyuan Qu, Bo Dai, Dingwei Ye et al.

 
 

This study aimed to investigate the role of AR-V7 in development of castration-resistant prostate cancer (CRPC) and to determine whether the AR-V7 expression in CRPC tissues can …

 
 
 
 
 
 

Thyrotropin and Obesity: Increased Adipose Triglyceride Content Through Glycerol-3-Phosphate Acyltransferase 3

 
 

Shizhan Ma, Fei Jing, Chao Xu et al.

 
 

Epidemiological evidence indicates that thyrotropin (TSH) is positively correlated with the severity of obesity. However, the mechanism remains unclear. Here, we show that TSH …

 
 
 
 
 
 

Hyaluronic acid prevents immunosuppressive drug-induced ovarian damage via up-regulating PGRMC1 expression

 
 

Guangfeng Zhao, Guijun Yan, Jie Cheng et al.

 
 

Chemotherapy treatment in women can frequently cause damage to the ovaries, which may lead to primary ovarian insufficiency (POI). In this study, we assessed the preventative …

 
 
 
 
 
 

MicroRNA-574-3p, identified by microRNA library-based functional screening, modulates tamoxifen response in breast cancer

 
 

T. Ujihira, K. Ikeda, T. Suzuki et al.

 
 

Most primary breast cancers express estrogen receptor α and can be treated via endocrine therapy using anti-estrogens such as tamoxifen; however, acquired endocrine resistance is …

 
 
 
 
 
 

A panel of five serum miRNAs as a potential diagnostic tool for early-stage renal cell carcinoma

 
 

Cheng Wang, Jicheng Hu, Meiling Lu et al.

 
 

Circulating microRNAs (miRNAs) are emerging as clinically useful tools for cancer detection; however, little is known about their early diagnostic impact on RCC. The levels of …

 
 
 
 
 
 

Effects of weight loss via high fat vs. low fat alternate day fasting diets on free fatty acid profiles

 
 

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Cardiovascular disease risk is associated with excess body weight and elevated plasma free fatty acid (FFA) concentrations. This study examines how an alternate-day fasting (ADF) …

 
 
 
 
 
 

G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

 
 

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Coronary atherosclerosis and myocardial infarction in postmenopausal women have been linked to inflammation and reduced nitric oxide (NO) formation. Natural estrogen exerts …

 
 
 
 
 
 

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Chigozie Anuli Mbadugha, Adeola Olukorede Onakoya

 
 

The awareness, perceptions and experiences of Nigerian Primary Open Angle Glaucoma (POAG) patients were assessed using a hospital based cross-sectional study design. One hundred …

 
 
 
 
 
 

Cardiac endothelial cell-derived exosomes induce specific regulatory B cells

 
 

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The mechanism of immune tolerance is to be further understood. The present study aims to investigate the role of the Cardiac endothelial cell (CEC)-derived exosomes in the …

 
 
 
 
 
 

A Simplified Method to Recover Urinary Vesicles for Clinical Applications, and Sample Banking

 
 

Luca Musante, Dorota Tataruch, Dongfeng Gu et al.

 
 

Urinary extracellular vesicles provide a novel source for valuable biomarkers for kidney and urogenital diseases: Current isolation protocols include laborious, sequential …

 
 
 
 
 
 
 
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