Cell Death and Differentiation - Table of Contents alert Volume 22 Issue 3

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Special issue on Autophagy in cell stress and death Autophagy plays a major housekeeping function in cells in thus far that it constitutes the major mechanism through which dysfunctional organelles and protein aggregates can be turned over. In addition, autophagy is elicited by multiple stress pathways, allowing cells to adapt to changing metabolic and other environmental cues. Until a certain threshold, the experimental induction of autophagy may increase the robustness of biological systems and reduce aging-associated processes including neurodegeneration. Beyond this threshold, however, autophagy can also cause the demise of cells. The present collection of reviews and original articles on autophagy illustrates the multiple physiological functions of, and pathological aberrations in, this important process. TABLE OF CONTENTS Volume 22, Issue 3 (March 2015) In this issue Editorial Reviews Original Papers Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Editorial Top Autophagy in stress and disease M Chiara Maiuri and G Kroemer Cell Death Differ 2015 22: 365-366; 10.1038/cdd.2014.236 Full Text | PDF Reviews Top Autosis and autophagic cell death: the dark side of autophagy OPEN Y Liu and B Levine Cell Death Differ 2015 22: 367-376; advance online publication, September 26, 2014; 10.1038/cdd.2014.143 Abstract | Full Text Oxidative stress and autophagy: the clash between damage and metabolic needs OPEN G Filomeni, D De Zio and F Cecconi Cell Death Differ 2015 22: 377-388; advance online publication, September 26, 2014; 10.1038/cdd.2014.150 Abstract | Full Text Autophagy and regulation of cilia function and assembly I Orhon, N Dupont, O Pampliega, A M Cuervo and P Codogno Cell Death Differ 2015 22: 389-397; advance online publication, October 31, 2014; 10.1038/cdd.2014.171 Abstract | Full Text Autophagy in the physiology and pathology of the central nervous system OPEN V Nikoletopoulou, M-E Papandreou and N Tavernarakis Cell Death Differ 2015 22: 398-407; advance online publication, December 19, 2014; 10.1038/cdd.2014.204 Abstract | Full Text Original Papers Top Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis F Rossin, M D'Eletto, L Falasca, S Sepe, S Cocco, G M Fimia, M Campanella, P G Mastroberardino, M G Farrace and M Piacentini Cell Death Differ 2015 22: 408-418; advance online publication, July 25, 2014; 10.1038/cdd.2014.106 Abstract | Full Text AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1 OPEN F Strappazzon, F Nazio, M Corrado, V Cianfanelli, A Romagnoli, G M Fimia, S Campello, R Nardacci, M Piacentini, M Campanella and F Cecconi Cell Death Differ 2015 22: 419-432; advance online publication, September 12, 2014; 10.1038/cdd.2014.139 Abstract | Full Text Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity OPEN F M Menzies, M Garcia-Arencibia, S Imarisio, N C O'Sullivan, T Ricketts, B A Kent, M V Rao, W Lam, Z W Green-Thompson, R A Nixon, L M Saksida, T J Bussey, C J O'Kane and D C Rubinsztein Cell Death Differ 2015 22: 433-444; advance online publication, September 26, 2014; 10.1038/cdd.2014.151 Abstract | Full Text The generation of neutrophils in the bone marrow is controlled by autophagy S Rožman, S Yousefi, K Oberson, T Kaufmann, C Benarafa and H U Simon Cell Death Differ 2015 22: 445-456; advance online publication, October 17, 2014; 10.1038/cdd.2014.169 Abstract | Full Text Vps15 is required for stress induced and developmentally triggered autophagy and salivary gland protein secretion in Drosophila A L Anding and E H Baehrecke Cell Death Differ 2015 22: 457-464; advance online publication, October 24, 2014; 10.1038/cdd.2014.174 Abstract | Full Text DAPK2 is a novel regulator of mTORC1 activity and autophagy OPEN Y Ber, R Shiloh, Y Gilad, N Degani, S Bialik and A Kimchi Cell Death Differ 2015 22: 465-475; advance online publication, October 31, 2014; 10.1038/cdd.2014.177 Abstract | Full Text Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa N Rodríguez-Muela, A M Hernández-Pinto, A Serrano-Puebla, L García-Ledo, S H Latorre, E J de la Rosa and P Boya Cell Death Differ 2015 22: 476-487; advance online publication, December 12, 2014; 10.1038/cdd.2014.203 Abstract | Full Text Autophagy supports survival and phototransduction protein levels in rod photoreceptors Z Zhou, T A Doggett, A Sene, R S Apte and T A Ferguson Cell Death Differ 2015 22: 488-498; advance online publication, January 9, 2015; 10.1038/cdd.2014.229 Abstract | Full Text Phosphatidylethanolamine positively regulates autophagy and longevity OPEN P Rockenfeller, M Koska, F Pietrocola, N Minois, O Knittelfelder, V Sica, J Franz, D Carmona-Gutierrez, G Kroemer and F Madeo Cell Death Differ 2015 22: 499-508; advance online publication, January 9, 2015; 10.1038/cdd.2014.219 Abstract | Full Text Spermidine induces autophagy by inhibiting the acetyltransferase EP300 F Pietrocola, S Lachkar, D P Enot, M Niso-Santano, J M Bravo-San Pedro, V Sica, V Izzo, M C Maiuri, F Madeo, G Mariño and G Kroemer Cell Death Differ 2015 22: 509-516; advance online publication, December 19, 2014; 10.1038/cdd.2014.215 Abstract | Full Text Corrigendum Top AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1 F Strappazzon, F Nazio, M Corrado, V Cianfanelli, A Romagnoli, G M Fimia, S Campello, R Nardacci, M Piacentini, M Campanella and F Cecconi Cell Death Differ 2015 22: 517; 10.1038/cdd.2014.190 Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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