Nature Reviews Cardiology - Table of Contents alert Volume 12 Issue 3

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TABLE OF CONTENTS
March 2015 Volume 12 Number 3
Impact Factor 10.154 *	In this issue Research Highlights News and Views Correspondence Reviews Also this month  Featured article: MicroRNAs in myocardial infarction Reinier A. Boon & Stefanie Dimmeler
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RESEARCH HIGHLIGHTS Top Biomarkers: High-sensitivity troponin assays for the diagnosis of AMI—sex-specific differences? Published online: 10 February 2015 p129 | doi:10.1038/nrcardio.2015.15 PDF Genetics: TTR and HF in black Americans Published online: 20 January 2015 p130 | doi:10.1038/nrcardio.2015.1 PDF Imaging: Combining IVUS and NIRS improves accuracy of fibroatheroma detection Published online: 27 January 2015 p130 | doi:10.1038/nrcardio.2015.3 PDF Dyslipidaemia: Statin therapy in men versus women Published online: 27 January 2015 p131 | doi:10.1038/nrcardio.2015.4 PDF Arrhythmias: Scar dechannelling limits amount of ablation needed to treat VT Published online: 03 February 2015 p131 | doi:10.1038/nrcardio.2015.8 PDF Interventional cardiology: TAVR improves survival in inoperable patients with severe aortic stenosis Published online: 03 February 2015 p131 | doi:10.1038/nrcardio.2015.9 PDF Risk factors: CVD risk prevention—40-year programme improves outcomes Published online: 03 February 2015 p132 | doi:10.1038/nrcardio.2015.10 PDF IN BRIEF Anticoagulation therapy: Dabigatran and rivaroxaban use in dialysis patients with AF | Atrial fibrillation: Digoxin use is associated with increased mortality in patients with AF regardless of concomitant heart failure | Lipids: Small, dense HDL subfractions are the most efficient mediators of cholesterol efflux PDF Cardiology JOBS of the week Two Independent Junior Research Group Leader Positions ? Vascular Biology - Neuroinflammation Institute for Stroke and Dementia Research (ISD) NIH funded postdoctoral position in the area of cardiac signal processing Massachusetts General Hospital PhD Studentship in Cardiac Modelling Gent University POSTDOC in Cardiopulmonary Molecular Biology Hannover Medical School (MHH) Scientist - Cardiovascular Pathology University Health Network (Toronto) More Science jobs from Cardiology EVENT World Congress of Cardiology & Cardiovascular Health 2016 04.06.16 Mexico City, Mexico More science events from
NEWS AND VIEWS		Top
Anticoagulation therapy: Perioperative anticoagulation—are we at 'a bridge too far'? James D. Douketis Published online: 03 February 2015 p133 | doi:10.1038/nrcardio.2015.7 The perioperative management of patients with atrial fibrillation who require an elective surgical or other invasive procedure is an area of ongoing uncertainty. Accumulating evidence from observational studies suggests that the use of bridging anticoagulation with heparin, although well-intentioned, might not reduce perioperative thromboembolism and can increase bleeding. Full Text | PDF
CORRESPONDENCE		Top
Early detection of pulmonary arterial hypertension: do not forget the right ventricle Gaetano Ruocco & Alberto Palazzuoli Published online: 13 January 2015 p134 | doi:10.1038/nrcardio.2014.191-c1 Full Text | PDF
REVIEWS		Top
MicroRNAs in myocardial infarction Reinier A. Boon & Stefanie Dimmeler Published online: 16 December 2014 p135 | doi:10.1038/nrcardio.2014.207 MicroRNAs regulate the processes that underlie cardiac remodelling after myocardial infarction, including angiogenesis and cardiomyocyte apoptosis and proliferation. In this Review, Boon and Dimmeler summarize the microRNAs that are involved with these postischaemic pathways, and discuss potential therapeutic interventions to enhance cardiac regeneration in patients with acute myocardial infarction. Abstract | Full Text | PDF
Early detection of pulmonary arterial hypertension Edmund M. T. Lau, Marc Humbert & David S. Celermajer Published online: 25 November 2014 p143 | doi:10.1038/nrcardio.2014.191 Pulmonary arterial hypertension (PAH) is an incurable disease associated with high mortality, but early detection of PAH improves long-term survival. In this Review, Lau and colleagues discuss which individuals warrant screening for PAH, such as those with systemic sclerosis, and summarize the variety of diagnostic tests that could be combined into a multimodal approach to optimize the performance of screening algorithms. Abstract | Full Text | PDF
Intramyocardial haemorrhage after acute myocardial infarction Ryanne P. Betgem, Guus A. de Waard, Robin Nijveldt, Aernout M. Beek, Javier Escaned & Niels van Royen Published online: 18 November 2014 p156 | doi:10.1038/nrcardio.2014.188 Although PCI can restore epicardial patency, microvascular blockage can occur in up to 50% of patients with acute myocardial infacrtion and lead to intramyocardial haemorrhage. In this Review, Betgem and colleagues discuss the pathophysiology, diagnostic options, and clinical relevance of intramyocardial haemorrhage, as well as potential future therapies to treat this condition. Abstract | Full Text | PDF
Cardiorheumatology: cardiac involvement in systemic rheumatic disease Megha Prasad, Joerg Hermann, Sherine E. Gabriel, Cornelia M. Weyand, Sharon Mulvagh, Rekha Mankad, Jae K. Oh, Eric L. Matteson & Amir Lerman Published online: 23 December 2014 p168 | doi:10.1038/nrcardio.2014.206 Rheumatological diseases can have a broad spectrum of cardiovascular manifestations that, whilst sometimes mild or clinically silent, can often increase morbidity and mortality. In this Review, Prasad et al. explore the underlying pathophysiology and available management strategies of cardiovascular complications in patients with autoimmune rheumatic diseases, and focus on the vascular aspects of the emerging field of 'cardiorheumatology'. Abstract | Full Text | PDF
Treatment of degenerative mitral regurgitation in elderly patients Maurizio Taramasso, Oliver Gaemperli & Francesco Maisano Published online: 23 December 2014 p177 | doi:10.1038/nrcardio.2014.210 In elderly patients with degenerative mitral regurgitation who are not ideal candidates for conventional surgical valve repair or replacement, percutaneous valve repair is emerging as an alternative therapeutic option. While percutaneous valve repair is associated with clinical improvement, faster recovery, and reduced perioperative mortality, it should only be considered in patients who will gain the most benefit from it. In this Review, Taramasso and colleagues discuss the treatment options and indications for degenerative mitral regurgitation in elderly patients. Abstract | Full Text | PDF
Diuretic response in acute heart failure—pathophysiology, evaluation, and therapy Jozine M. ter Maaten, Mattia A. E. Valente, Kevin Damman, Hans L. Hillege, Gerjan Navis & Adriaan A. Voors Published online: 06 January 2015 p184 | doi:10.1038/nrcardio.2014.215 Resistance to diuretic therapy to achieve decongestion is common in patients with acute heart failure. In this Review, ter Maaten and colleagues describe the pathophysiology and mechanisms of diuretic resistance, how to evaluate diuretic response, and propose a treatment strategy for patients with acute heart failure who are diuretic resistant. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2013. Nature Reviews Cardiology was previously published as Nature Clinical Practice Cardiovascular Medicine.

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