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2015/02/17

Scientific Reports Table of Contents e-alert: 17 February 2015

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  17 February 2015   
 
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Nature Reviews Clinical Oncology 
FREE POSTER: BREAST CANCER INTRINSIC SUBTYPES 
 
This special Poster highlights recent achievements and development of our genetic understanding of the intrinsic subtypes of molecular breast cancer subtypes.
 
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Effects of subconscious and conscious emotions on human cue–reward association learning

 
 

Noriya Watanabe, Masahiko Haruno

 
 

Life demands that we adapt our behaviour continuously in situations in which much of our incoming information is emotional and unrelated to our immediate behavioural goals. Such …

 
 
 
 
 
 

A Novel Protocol for Model Calibration in Biological Wastewater Treatment

 
 

Ao Zhu, Jianhua Guo, Bing-Jie Ni et al.

 
 

Activated sludge models (ASMs) have been widely used for process design, operation and optimization in wastewater treatment plants. However, it is still a challenge to achieve an …

 
 
 
 
 
 

Diverse fungi associated with partial irregular heartwood of Dalbergia odorifera

 
 

Sisheng Sun, Xu Zeng, Dawei Zhang et al.

 
 

Dalbergia odorifera T. Chen is a medium-sized evergreen tree that produces purple-brown heartwood called JiangXiang in traditional Chinese medicine, the formation process of …

 
 
 
 
 
 

Double minute amplification of mutant PDGF receptor α in a mouse glioma model

 
 

Hongyan Zou, Rui Feng, Yong Huang et al.

 
 

In primary brain tumors, oncogenes are frequently amplified and maintained on extrachromosomal DNA as double minutes (DM), but the underlying mechanisms remain poorly understood. …

 
 
 
 
 
 

hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold

 
 

Ruodan Xu, Mehmet Berat Taskin, Marina Rubert et al.

 
 

Fibroblasts are ubiquitous cells that constitute the stroma of virtually all tissues and play vital roles in homeostasis. The poor innate healing capacity of fibroblastic tissues …

 
 
 
 
 
 

Lentivirus-mediated Inhibition of Tumour Necrosis Factor-α improves motor function associated with PRDX6 in spinal cord contusion rats

 
 

Xiao Zhang, Lan-lan Shi, Xia Gao et al.

 
 

The recovery of motor function in rats is inhibited following contusion spinal cord injury (cSCI). However, the mechanism of tumour necrosis factor α (TNF-α) in motor function …

 
 
 
 
 
 

Defoliation of interior Douglas-fir elicits carbon transfer and stress signalling to ponderosa pine neighbors through ectomycorrhizal networks

 
 

Yuan Yuan Song, Suzanne W. Simard, Allan Carroll et al.

 
 

Extensive regions of interior Douglas-fir (Pseudotsuga menziesii var. glauca, IDF) forests in North America are being damaged by drought and western spruce budworm (Choristoneura …

 
 
 
 
 
 

Illumina sequencing-based analysis of free-living bacterial community dynamics during an Akashiwo sanguine bloom in Xiamen sea, China

 
 

Caiyun Yang, Yi Li, Benjamin Zhou et al.

 
 

Although phytoplankton are the major source of marine dissolved organic matter (DOM), their blooms are a global problem that can greatly affect marine ecological systems, …

 
 
 
 
 
 

An integrative analysis of TFBS-clustered regions reveals new transcriptional regulation models on the accessible chromatin landscape

 
 

Hebing Chen, Hao Li, Feng Liu et al.

 
 

DNase I hypersensitive sites (DHSs) define the accessible chromatin landscape and have revolutionised the discovery of distinct cis-regulatory elements in diverse organisms. …

 
 
 
 
 
 

Carnival or football, is there a real risk for acquiring dengue fever in Brazil during holidays seasons?

 
 

Maíra Aguiar, Filipe Rocha, José Eduardo Marques Pessanha et al.

 
 

More than 600,000 football fans, coming from all over the world, were expected to visit Brazil during the FIFA World Cup 2014. International travel can become a public health …

 
 
 
 
 
 

Temperature and solids retention time control microbial population dynamics and volatile fatty acid production in replicated anaerobic digesters

 
 

Inka Vanwonterghem, Paul D. Jensen, Korneel Rabaey et al.

 
 

Anaerobic digestion is a widely used technology for waste stabilization and generation of biogas, and has recently emerged as a potentially important process for the production …

 
 
 
 
 
 

ERRATUM: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions

 
 

Jin Young Joo, Hyun Woo Choi, Min Jung Kim et al.

 
 

 
 
 
 
 
 

Revealing the favorable dissociation pathway of type II kinase inhibitors via enhanced sampling simulations and two-end-state calculations

 
 

Huiyong Sun, Sheng Tian, Shunye Zhou et al.

 
 

How does a type II inhibitor bind to/unbind from a kinase target is still a confusing question because the small molecule occupies both the ATP pocket and the allosteric pocket …

 
 
 
 
 
 

A neuro-inspired model-based closed-loop neuroprosthesis for the substitution of a cerebellar learning function in anesthetized rats

 
 

Roni Hogri, Simeon A. Bamford, Aryeh H. Taub et al.

 
 

Neuroprostheses could potentially recover functions lost due to neural damage. Typical neuroprostheses connect an intact brain with the external environment, thus replacing …

 
 
 
 
 
 

On forward inferences of fast and slow readers. An eye movement study

 
 

Stefan Hawelka, Sarah Schuster, Benjamin Gagl et al.

 
 

Unimpaired readers process words incredibly fast and hence it was assumed that top-down processing, such as predicting upcoming words, would be too slow to play an appreciable …

 
 
 
 
 
 

An ESCRT module is required for neuron pruning

 
 

Nicolas Loncle, Monica Agromayor, Juan Martin-Serrano et al.

 
 

Neural circuits are refined by both functional and structural changes. Structural remodeling by large-scale pruning occurs where relatively long neuronal branches are cut away …

 
 
 
 
 
 

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

 
 

Pulin Che, Youfeng Yang, Xiaosi Han et al.

 
 

S100A4 expression is associated with poor clinical outcomes of patients with pancreatic cancer. The effects of loss or gain of S100A4 were examined in pancreatic cancer cell …

 
 
 
 
 
 

Terahertz in-line digital holography of human hepatocellular carcinoma tissue

 
 

Lu Rong, Tatiana Latychevskaia, Chunhai Chen et al.

 
 

Terahertz waves provide a better contrast in imaging soft biomedical tissues than X-rays, and unlike X-rays, they cause no ionisation damage, making them a good option for …

 
 
 
 
 
 

How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila

 
 

R. Faville, B. Kottler, G. J. Goodhill et al.

 
 

The fruitfly, Drosophila melanogaster, has become a critical model system for investigating sleep functions. Most studies use duration of inactivity to measure sleep. However, a …

 
 
 
 
 
 

ycf1, the most promising plastid DNA barcode of land plants

 
 

Wenpan Dong, Chao Xu, Changhao Li et al.

 
 

A DNA barcode is a DNA fragment used to identify species. For land plants, DNA fragments of plastid genome could be the primary consideration. Unfortunately, most of the plastid …

 
 
 
 
 
 

Differential regulation of the hmsCDE operon in Yersinia pestis and Yersinia pseudotuberculosis by the Rcs phosphorelay system

 
 

Xiao-Peng Guo, Gai-Xian Ren, Hui Zhu et al.

 
 

Yersinia pestis, the agent of plague, forms a biofilm in its flea vector to enhance transmission. Y. pestis biofilm development is positively regulated by hmsT and hmsD, encoding …

 
 
 
 
 
 

Community structure of gut fungi during different developmental stages of the Chinese white pine beetle (Dendroctonus armandi)

 
 

Xia Hu, Ming Li, Hui Chen

 
 

The Chinese white pine beetle is arguably the most destructive forest insect in the Qinling Mountains in Northern China. Little is known about the structure of the fungal …

 
 
 
 
 
 

The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains

 
 

J. L. Perez Velazquez, R. Guevara Erra, M. Rosenblum

 
 

The rhythmic activity observed in nervous systems, in particular in epilepsies and Parkinson's disease, has often been hypothesized to originate from a macroscopic self-sustained …

 
 
 
 
 
 

Winners and losers in a world where the high seas is closed to fishing

 
 

U. Rashid Sumaila, Vicky W. Y. Lam, Dana D. Miller et al.

 
 

Fishing takes place in the high seas and Exclusive Economic Zones (EEZs) of maritime countries. Closing the former to fishing has recently been proposed in the literature and is …

 
 
 
 
 
 

Mechanistic insight into the functional transition of the enzyme guanylate kinase induced by a single mutation

 
 

Yuebin Zhang, Huiyan Niu, Yan Li et al.

 
 

Dramatic functional changes of enzyme usually require scores of alterations in amino acid sequence. However, in the case of guanylate kinase (GK), the functional novelty is …

 
 
 
 
 
 

A proof-of-principle study of multi-site real-time functional imaging at 3T and 7T: Implementation and validation

 
 

Sebastian Baecke, Ralf Lützkendorf, Johannes Mallow et al.

 
 

Real-time functional Magnetic Resonance Imaging (rtfMRI) is used mainly for neurofeedback or for brain-computer interfaces (BCI). But multi-site rtfMRI could in fact help in the …

 
 
 
 
 
 

The metabolic responses to hepatitis B virus infection shed new light on pathogenesis and targets for treatment

 
 

Hongde Li, Wandi Zhu, Leike Zhang et al.

 
 

Chronic infection caused by the hepatitis B virus (HBV), is strongly associated with hepatitis, fatty liver and hepatocellular carcinoma. To investigate the underlying …

 
 
 
 
 
 

A statistically inferred microRNA network identifies breast cancer target miR-940 as an actin cytoskeleton regulator

 
 

Ricky Bhajun, Laurent Guyon, Amandine Pitaval et al.

 
 

MiRNAs are key regulators of gene expression. By binding to many genes, they create a complex network of gene co-regulation. Here, using a network-based approach, we identified …

 
 
 
 
 
 

The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines

 
 

Kazuyoshi Kobayashi, Kouhei Sakurai, Hiroaki Hiramatsu et al.

 
 

In epithelial cells, miRNA-199a-5p/-3p and Brm, a catalytic subunit of the SWI/SNF complex were previously shown to form a double-negative feedback loop through EGR1, by which …

 
 
 
 
 
 

Climate change as an unexpected co-factor promoting coral eating seastar (Acanthaster planci) outbreaks

 
 

S. Uthicke, M. Logan, M. Liddy et al.

 
 

Coral reefs face a crisis due to local and global anthropogenic stressors. A large proportion of the ~50% coral loss on the Great Barrier Reef has been attributed to outbreaks of …

 
 
 
 
 
 

CORRIGENDUM: A Comparative Study of Fast-Track Versus Conventional Surgery in Patients Undergoing Laparoscopic Radical Cystectomy and Ileal Conduit Diversion: Chinese Experience

 
 

Xiao Guan, Longfei Liu, Xiang Lei et al.

 
 

 
 
 
 
 
 

Transcriptional response to petiole heat girdling in cassava

 
 

Yang Zhang, Zehong Ding, Fangfang Ma et al.

 
 

To examine the interactions of starch and sugar metabolism on photosynthesis in cassava, a heat-girdling treatment was applied to petioles of cassava leaves at the end of the …

 
 
 
 
 
 

Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase

 
 

Elena Formoso, Vittorio Limongelli, Michele Parrinello

 
 

Adenylate Kinase (AK) is a signal transducing protein that regulates cellular energy homeostasis balancing between different conformations. An alteration of its activity can lead …

 
 
 
 
 
 

Chromatin modifications and genomic contexts linked to dynamic DNA methylation patterns across human cell types

 
 

Haidan Yan, Dongwei Zhang, Hongbo Liu et al.

 
 

DNA methylation is related closely to sequence contexts and chromatin modifications; however, their potential differences in different genomic regions across cell types remain …

 
 
 
 
 
 

SIRT2 is involved in the modulation of depressive behaviors

 
 

Rui Liu, Wei Dang, Ying Du et al.

 
 

Exposure to chronic stress produces negative effects on mood and hippocampus-dependent memory formation. SIRT2 alteration has been reported in mood disorders; however, the role …

 
 
 
 
 
 

CORRIGENDUM: Micromonospora from nitrogen fixing nodules of alfalfa (Medicago sativa L.). A new promising Plant Probiotic Bacteria

 
 

Pilar Martínez-Hidalgo, Purificación Galindo-Villardón, Martha E. Trujillo et al.

 
 

 
 
 
 
 
 

Fear renewal preferentially activates ventral hippocampal neurons projecting to both amygdala and prefrontal cortex in rats

 
 

Jingji Jin, Stephen Maren

 
 

Anxiety, trauma and stress-related disorders are often characterized by a loss of context-appropriate emotional responding. The contextual retrieval of emotional memory involves …

 
 
 
 
 
 

A genetic contribution from the Far East into Ashkenazi Jews via the ancient Silk Road

 
 

Jiao-Yang Tian, Hua-Wei Wang, Yu-Chun Li et al.

 
 

Contemporary Jews retain a genetic imprint from their Near Eastern ancestry, but obtained substantial genetic components from their neighboring populations during their history. …

 
 
 
 
 
 

CORRIGENDUM: DNA methylome in spleen of avian pathogenic escherichia coli-challenged broilers and integration with mRNA expression

 
 

Haiping Xu, Xuenong Zhu, Yongsheng Hu et al.

 
 

 
 
 
 
 
 

Involvement of dachshund and Distal-less in distal pattern formation of the cricket leg during regeneration

 
 

Yoshiyasu Ishimaru, Taro Nakamura, Tetsuya Bando et al.

 
 

Cricket nymphs have the remarkable ability to regenerate a functional leg following amputation, indicating that the regenerating blastemal cells contain information for leg …

 
 
 
 
 
 

Integrin-Linked Kinase links Dynactin-1/Dynactin-2 with cortical Integrin receptors to orient the mitotic spindle relative to the substratum

 
 

Edward James Morris, Kiran Assi, Baljinder Salh et al.

 
 

Cells must divide strictly along a plane to form an epithelial layer parallel to the basal lamina. The axis of cell division is primarily governed by the orientation of the …

 
 
 
 
 
 

Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia

 
 

Julien Hiblot, Janek Bzdrenga, Charlotte Champion et al.

 
 

A new representative of the Phosphotriesterase-Like Lactonases (PLLs) family from the hyperthermophilic crenarchaeon Vulcanisaeta moutnovskia has been characterized and …

 
 
 
 
 
 

Circadian rhythm phase shifts and endogenous free-running circadian period differ between African-Americans and European-Americans

 
 

Charmane I. Eastman, Christina Suh, Victoria A. Tomaka et al.

 
 

Successful adaptation to modern civilization requires the internal circadian clock to make large phase shifts in response to circumstances (e.g., jet travel and shift work) that …

 
 
 
 
 
 

A Green Strategy to Prepare Metal Oxide Superstructure from Metal-Organic Frameworks

 
 

Yonghai Song, Xia Li, Changting Wei et al.

 
 

Metal or metal oxides with diverse superstructures have become one of the most promising functional materials in sensor, catalysis, energy conversion, etc. In this work, a novel …

 
 
 
 
 
 

Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation

 
 

Theerthankar Das, Samuel K. Kutty, Roya Tavallaie et al.

 
 

Bacterial resistance to conventional antibiotics necessitates the identification of novel leads for infection control. Interference with extracellular phenomena, such as quorum …

 
 
 
 
 
 

Down-Regulation of Human Enteric Antimicrobial Peptides by NOD2 during Differentiation of the Paneth Cell Lineage

 
 

Gao Tan, Run-hua Li, Chen Li et al.

 
 

Ileal Crohn's disease (CD) arising from the alteration of intestinal homeostasis is characterized by two features, namely a decrease in Paneth cell-produced antimicrobial …

 
 
 
 
 
 

Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain

 
 

Jennifer Fazzari, Hanxin Lin, Cecilia Murphy et al.

 
 

Glutamate is an important signaling molecule in a wide variety of tissues. Aberrant glutamatergic signaling disrupts normal tissue homeostasis and induces several disruptive …

 
 
 
 
 
 

Fitness Profiling Links Topoisomerase II Regulation of Centromeric Integrity to Doxorubicin Resistance in Fission Yeast

 
 

Thi Thuy Trang Nguyen, Julia Sze Lynn Lim, Richard Ming Yi Tang et al.

 
 

Doxorubicin, a chemotherapeutic agent, inhibits the religation step of topoisomerase II (Top2). However, the downstream ramifications of this action are unknown. Here we …

 
 
 
 
 
 

Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells

 
 

Aeyung Kim, Minju Im, Jin Yeul Ma

 
 

Remotiflori radix is the root of Mosidae, which has long been used as a traditional medicine to treat chills, fever, and phlegm discharge. The ethanol extract of Mosidae leaves …

 
 
 
 
 
 

The Genetics of POAG in Black South Africans: A Candidate Gene Association Study

 
 

Susan E. I. Williams, Trevor R. Carmichael, R. Rand Allingham et al.

 
 

Multiple loci have been associated with either primary open angle glaucoma (POAG) or heritable ocular quantitative traits associated with this condition. This study examined the …

 
 
 
 
 
 

A high-resolution 2D J-resolved NMR detection technique for metabolite analyses of biological samples

 
 

Yuqing Huang, Zhiyong Zhang, Hao Chen et al.

 
 

NMR spectroscopy is a commonly used technique for metabolite analyses. Due to the observed macroscopic magnetic susceptibility in biological tissues, current NMR acquisitions in …

 
 
 
 
 
 

Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis

 
 

Jie Tian, Chuan Tian, Yuehe Ding et al.

 
 

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurologic disorder caused by ATTCT expansion in the ATXN10 gene. Previous investigations have identified that …

 
 
 
 
 
 

Attentional modulations of the early and later stages of the neural processing of visual completion

 
 

Xiang Wu, Liang Zhou, Cheng Qian et al.

 
 

The brain effortlessly recognizes objects even when the visual information belonging to an object is widely separated, as well demonstrated by the Kanizsa-type illusory contours …

 
 
 
 
 
 

The tomato borer, Tuta absoluta, invading the Mediterranean Basin, originates from a single introduction from Central Chile

 
 

Thomas Guillemaud, Aurélie Blin, Isabelle Le Goff et al.

 
 

The Lepidopteran pest of tomato, Tuta absoluta, is native to South America and is invasive in the Mediterranean basin. The species' routes of invasion were investigated. The …

 
 
 
 
 
 

Fast Super-Resolution Imaging with Ultra-High Labeling Density Achieved by Joint Tagging Super-Resolution Optical Fluctuation Imaging

 
 

Zhiping Zeng, Xuanze Chen, Hening Wang et al.

 
 

Previous stochastic localization-based super-resolution techniques are largely limited by the labeling density and the fidelity to the morphology of specimen. We report on an …

 
 
 
 
 
 

FGF23 neutralization improves bone quality and osseointegration of titanium implants in chronic kidney disease mice

 
 

Ningyuan Sun, Yuchen Guo, Weiqing Liu et al.

 
 

Chronic kidney disease (CKD) is a worldwide health problem. Serum levels of FGF23, a phosphaturic hormone, increase at the earliest stages of CKD, and have been found to be …

 
 
 
 
 
 

RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes

 
 

Thomas Brettin, James J. Davis, Terry Disz et al.

 
 

The RAST (Rapid Annotation using Subsystem Technology) annotation engine was built in 2008 to annotate bacterial and archaeal genomes. It works by offering a standard software …

 
 
 
 
 
 

Quantitative analysis of injury-induced anterior subcapsular cataract in the mouse: a model of lens epithelial cells proliferation and epithelial-mesenchymal transition

 
 

Wei Xiao, Xiaoyun Chen, Weihua Li et al.

 
 

The mouse lens capsular injury model has been widely used in investigating the mechanisms of anterior subcapsular cataract (ASC) and posterior capsule opacification (PCO), and …

 
 
 
 
 
 

The molecular architecture of dihydropyrindine receptor/L-type Ca2+ channel complex

 
 

Hongli Hu, Zhao Wang, Risheng Wei et al.

 
 

Dihydropyridine receptor (DHPR), an L-type Ca2 channel complex, plays an essential role in muscle contraction, secretion, integration of synaptic input in neurons and synaptic …

 
 
 
 
 
 

CRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes

 
 

Hua Zhong, Yiyun Chen, Yumei Li et al.

 
 

The era of genomics has demanded the development of more efficient and timesaving approaches to validate gene function in disease. Here, we utilized the CRISPR-Cas9 system to …

 
 
 
 
 
 

Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells

 
 

Taku Tanaka, Tadashi Yokoi, Fuminobu Tamalu et al.

 
 

We generated self-induced retinal ganglion cells (RGCs) with functional axons from human induced pluripotent stem cells. After development of the optic vesicle from the induced …

 
 
 
 
 
 

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

 
 

Chouyang Li, Simin Rezania, Sarah Kammerer et al.

 
 

Mechanical interaction between cells – specifically distortion of tensional homeostasis-emerged as an important aspect of breast cancer genesis and progression. We investigated …

 
 
 
 
 
 

Accuracy and efficiency of detection dogs: a powerful new tool for koala conservation and management

 
 

Romane H. Cristescu, Emily Foley, Anna Markula et al.

 
 

Accurate data on presence/absence and spatial distribution for fauna species is key to their conservation. Collecting such data, however, can be time consuming, laborious and …

 
 
 
 
 
 

Extensive load of somatic CNVs in the human placenta

 
 

Laura Kasak, Kristiina Rull, Pille Vaas et al.

 
 

Placenta is a temporary, but indispensable organ in mammalian pregnancy. From its basic nature, it exhibits highly invasive tumour-like properties facilitating effective …

 
 
 
 
 
 

A Ligand-observed Mass Spectrometry Approach Integrated into the Fragment Based Lead Discovery Pipeline

 
 

Xin Chen, Shanshan Qin, Shuai Chen et al.

 
 

In fragment-based lead discovery (FBLD), a cascade combining multiple orthogonal technologies is required for reliable detection and characterization of fragment binding to the …

 
 
 
 
 
 

Earth's Phosphides in Levant and insights into the source of Archean prebiotic phosphorus

 
 

Sergey N. Britvin, Michail N. Murashko, Yevgeny Vapnik et al.

 
 

Natural phosphides - the minerals containing phosphorus in a redox state lower than zero – are common constituents of meteorites but virtually unknown on the Earth. Herein we …

 
 
 
 
 
 

IER3 is a crucial mediator of TAp73β-induced apoptosis in cervical cancer and confers etoposide sensitivity

 
 

Hanyong Jin, Dae-Shik Suh, Tae-Hyoung Kim et al.

 
 

Infection with high-risk human papillomaviruses (HPVs) causes cervical cancer. E6 oncoprotein, an HPV gene product, inactivates the major gatekeeper p53. In contrast, its …

 
 
 
 
 
 

Strong effects of ionizing radiation from Chernobyl on mutation rates

 
 

Anders Pape Møller, Timothy A. Mousseau

 
 

In this paper we use a meta-analysis to examine the relationship between radiation and mutation rates in Chernobyl across 45 published studies, covering 30 species. Overall …

 
 
 
 
 
 

Transferable neuronal mini-cultures to accelerate screening in primary and induced pluripotent stem cell-derived neurons

 
 

Mark Niedringhaus, Raluca Dumitru, Angela M. Mabb et al.

 
 

The effort and cost of obtaining neurons for large-scale screens has limited drug discovery in neuroscience. To overcome these obstacles, we fabricated arrays of releasable …

 
 
 
 
 
 

Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection

 
 

A. Christy Wyckoff, Nathan Galloway, Crystal Meyerett-Reid et al.

 
 

Prions are unique infectious agents that replicate without a genome and cause neurodegenerative diseases that include chronic wasting disease (CWD) of cervids. …

 
 
 
 
 
 

Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines

 
 

Benoit Briard, Perrine Bomme, Beatrix E. Lechner et al.

 
 

The opportunistic fungal pathogen Aspergillus fumigatus is increasingly found as a coinfecting agent along with Pseudomonas aeruginosa in cystic fibrosis patients. Amongst the …

 
 
 
 
 
 
   
 
 
Chemical Sciences top
 
 
 
 
 
 
 

ZnO Nanocomposites Modified by Hydrophobic and Hydrophilic Silanes with Dramatically Enhanced Tunable Fluorescence and Aqueous Ultrastability toward Biological Imaging Applications

 
 

Shuying Li, Zongzhao Sun, Rui Li et al.

 
 

Multicolor ZnO quantum dots (QDs) were synthesized and further modified with hydrophobic hexadecyltrimethoxysilane (HDS) and then hydrophilic aminopropyltriethoxysilane (APS) …

 
 
 
 
 
 

Visualization of Endogenous and Exogenous Hydrogen Peroxide Using A Lysosome-Targetable Fluorescent Probe

 
 

Dabin Kim, Gyoungmi Kim, Sang-Jip Nam et al.

 
 

Reactive oxygen species (ROS) play crucial roles in diverse physiological processes; therefore, the efficient detection of ROS is very crucial. In this study, we report a …

 
 
 
 
 
 

Thickness Dependent Effective Viscosity of a Polymer Solution near an Interface Probed by a Quartz Crystal Microbalance with Dissipation Method

 
 

Jiajie Fang, Tao Zhu, Jie Sheng et al.

 
 

The solution viscosity near an interface, which affects the solution behavior and the molecular dynamics in the solution, differs from the bulk. This paper measured the effective …

 
 
 
 
 
 

Controlled Synthesis of Pd/Pt Core Shell Nanoparticles Using Area-selective Atomic Layer Deposition

 
 

Kun Cao, Qianqian Zhu, Bin Shan et al.

 
 

We report an atomic scale controllable synthesis of Pd/Pt core shell nanoparticles (NPs) via area-selective atomic layer deposition (ALD) on a modified surface. The method …

 
 
 
 
 
 

Facile fabrication of various zinc-nickel citrate microspheres and their transformation to ZnO-NiO hybrid microspheres with excellent lithium storage properties

 
 

Qingshui Xie, Yating Ma, Deqian Zeng et al.

 
 

Zinc-nickel citrate microspheres are prepared by a simple aging process of zinc citrate solid microspheres in nickel nitrate solution. As the concentration of nickel nitrate …

 
 
 
 
 
 

An Effect of Molecular Motion on Carrier Formation in a Poly(3-hexylthiophene) Film

 
 

Yudai Ogata, Daisuke Kawaguchi, Keiji Tanaka

 
 

Free carriers, polarons (P), in conjugated polymers play a key role in the performance of optoelectronic devices. Here, we present solid evidence that P can be predominantly …

 
 
 
 
 
 

Facile synthesis of novel graphene sponge for high performance capacitive deionization

 
 

Xingtao Xu, Likun Pan, Yong Liu et al.

 
 

Capacitive deionization (CDI) is an effective desalination technique offering an appropriate route to obtain clean water. In order to obtain excellent CDI performance, a …

 
 
 
 
 
 

Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase

 
 

Elena Formoso, Vittorio Limongelli, Michele Parrinello

 
 

Adenylate Kinase (AK) is a signal transducing protein that regulates cellular energy homeostasis balancing between different conformations. An alteration of its activity can lead …

 
 
 
 
 
 

Dependence of structure and temperature for lithium-rich layered-spinel microspheres cathode material of lithium ion batteries

 
 

Di Wang, Ruizhi Yu, Xianyou Wang et al.

 
 

Homogeneous lithium-rich layered-spinel 0.5Li2MnO3·0.5LiMn1/3Ni1/3Co1/3O2 microspheres (~1 μm) are successfully prepared by a solvothermal method and subsequent high-temperature …

 
 
 
 
 
 

Inexpensive Antimony Nanocrystals and Their Composites with Red Phosphorus as High-Performance Anode Materials for Na-ion Batteries

 
 

Marc Walter, Rolf Erni, Maksym V. Kovalenko

 
 

Sodium-ion batteries increasingly become of immense research interest as a potential inexpensive alternative to Lithium-ion batteries. Development of high-energy-density negative …

 
 
 
 
 
 

Role of Co-Vapors in Vapor Deposition Polymerization

 
 

Ji Eun Lee, Younghee Lee, Ki-Jin Ahn et al.

 
 

Polypyrrole (PPy)/cellulose (PPCL) composite papers were fabricated by vapor phase polymerization. Importantly, the vapor-phase deposition of PPy onto cellulose was assisted by …

 
 
 
 
 
 

Tape Transfer Atomization Patterning of Liquid Alloys for Microfluidic Stretchable Wireless Power Transfer

 
 

Seung Hee Jeong, Klas Hjort, Zhigang Wu

 
 

Stretchable electronics offers unsurpassed mechanical compliance on complex or soft surfaces like the human skin and organs. To fully exploit this great advantage, an autonomous …

 
 
 
 
 
 

Hybrid luminescence materials assembled by [Ln(DPA)3]3− and mesoporous host through ion-pairing interactions with high quantum efficiencies and long lifetimes

 
 

Qing-Feng Li, Dan Yue, Wei Lu et al.

 
 

A kind of mesoporous hybrid luminescence material was assembled through the ion exchange method between [Ln(DPA)3]3− and ionic liquid functionalized SBA-15. [Ln(DPA)3]3− was …

 
 
 
 
 
 

Minimising hydrogen sulphide generation during steam assisted production of heavy oil

 
 

Wren Montgomery, Mark A. Sephton, Jonathan S. Watson et al.

 
 

The majority of global petroleum is in the form of highly viscous heavy oil. Traditionally heavy oil in sands at shallow depths is accessed by large scale mining activities. …

 
 
 
 
 
 

Tuning Interior Nanogaps of Double-shelled Au/Ag Nanoboxes for Surface-Enhanced Raman Scattering

 
 

Weiqing Zhang, Mohsen Rahmani, Wenxin Niu et al.

 
 

Double-shelled Au/Ag hollow nanoboxes with precisely controlled interior nanogaps (1 to 16 nm) were synthesized for gap-tunable surface-enhanced Raman scattering (SERS). The …

 
 
 
 
 
 

Microscopic Receding Contact Line Dynamics on Pillar and Irregular Superhydrophobic Surfaces

 
 

Yong Han Yeong, Athanasios Milionis, Eric Loth et al.

 
 

Receding angles have been shown to have great significance when designing a superhydrophobic surface for applications involving self-cleaning. Although apparent receding angles …

 
 
 
 
 
 

Efficient Organic Photovoltaics Utilizing Nanoscale Heterojunctions in Sequentially Deposited Polymer/fullerene Bilayer

 
 

Jeesoo Seok, Tae Joo Shin, Sungmin Park et al.

 
 

A highly efficient sequentially deposited bilayer (SD-bilayer) of polymer/fullerene organic photovoltaic (OPV) device is developed via the solution process. Herein, we resolve …

 
 
 
 
 
 

A high-resolution 2D J-resolved NMR detection technique for metabolite analyses of biological samples

 
 

Yuqing Huang, Zhiyong Zhang, Hao Chen et al.

 
 

NMR spectroscopy is a commonly used technique for metabolite analyses. Due to the observed macroscopic magnetic susceptibility in biological tissues, current NMR acquisitions in …

 
 
 
 
 
 

A simple method for tuning the glass transition process in inorganic phosphate glasses

 
 

René Fulchiron, Imane Belyamani, Joshua U. Otaigbe et al.

 
 

The physical modification of glass transition temperature (Tg) and properties of materials via blending is a common practice in industry and academia and has a large economic …

 
 
 
 
 
 
 
 

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Omnidirectional color filters capitalizing on a nano-resonator of Ag-TiO2-Ag integrated with a phase compensating dielectric overlay

 
 

Chul-Soon Park, Vivek Raj Shrestha, Sang-Shin Lee et al.

 
 

We present a highly efficient omnidirectional color filter that takes advantage of an Ag-TiO2-Ag nano-resonator integrated with a phase-compensating TiO2 overlay. The dielectric …

 
 
 
 
 
 

Organic Fluorescent Dyes Supported on Activated Boron Nitride: A Promising Blue Light Excited Phosphors for High-Performance White Light-Emitting Diodes

 
 

Jie Li, Jing Lin, Yang Huang et al.

 
 

We report an effective and rare-earth free light conversion material synthesized via a facile fabrication route, in which organic fluorescent dyes, i.e. Rhodamine B (RhB) and …

 
 
 
 
 
 

ZnO Nanocomposites Modified by Hydrophobic and Hydrophilic Silanes with Dramatically Enhanced Tunable Fluorescence and Aqueous Ultrastability toward Biological Imaging Applications

 
 

Shuying Li, Zongzhao Sun, Rui Li et al.

 
 

Multicolor ZnO quantum dots (QDs) were synthesized and further modified with hydrophobic hexadecyltrimethoxysilane (HDS) and then hydrophilic aminopropyltriethoxysilane (APS) …

 
 
 
 
 
 

Visualization of Endogenous and Exogenous Hydrogen Peroxide Using A Lysosome-Targetable Fluorescent Probe

 
 

Dabin Kim, Gyoungmi Kim, Sang-Jip Nam et al.

 
 

Reactive oxygen species (ROS) play crucial roles in diverse physiological processes; therefore, the efficient detection of ROS is very crucial. In this study, we report a …

 
 
 
 
 
 

Design, Implementation and Characterization of a Quantum-Dot-Based Volumetric Display

 
 

Ryuji Hirayama, Makoto Naruse, Hirotaka Nakayama et al.

 
 

In this study, we propose and experimentally demonstrate a volumetric display system based on quantum dots (QDs) embedded in a polymer substrate. Unlike conventional volumetric …

 
 
 
 
 
 

Thickness Dependent Effective Viscosity of a Polymer Solution near an Interface Probed by a Quartz Crystal Microbalance with Dissipation Method

 
 

Jiajie Fang, Tao Zhu, Jie Sheng et al.

 
 

The solution viscosity near an interface, which affects the solution behavior and the molecular dynamics in the solution, differs from the bulk. This paper measured the effective …

 
 
 
 
 
 

Aluminum nitride nanowire light emitting diodes: Breaking the fundamental bottleneck of deep ultraviolet light sources

 
 

S. Zhao, A. T. Connie, M. H. T. Dastjerdi et al.

 
 

Despite broad interest in aluminum gallium nitride (AlGaN) optoelectronic devices for deep ultraviolet (DUV) applications, the performance of conventional Al(Ga)N planar devices …

 
 
 
 
 
 

Phosphate ytterbium-doped single-mode all-solid photonic crystal fiber with output power of 13.8 W

 
 

Longfei Wang, Dongbing He, Suya Feng et al.

 
 

Single-mode ytterbium-doped phosphate all-solid photonic crystal fiber (AS-PCF) with 13.8 W output power and 32% slope efficiency was reported. By altering the diameter of the …

 
 
 
 
 
 

Facile fabrication of various zinc-nickel citrate microspheres and their transformation to ZnO-NiO hybrid microspheres with excellent lithium storage properties

 
 

Qingshui Xie, Yating Ma, Deqian Zeng et al.

 
 

Zinc-nickel citrate microspheres are prepared by a simple aging process of zinc citrate solid microspheres in nickel nitrate solution. As the concentration of nickel nitrate …

 
 
 
 
 
 

Controlled Synthesis of Pd/Pt Core Shell Nanoparticles Using Area-selective Atomic Layer Deposition

 
 

Kun Cao, Qianqian Zhu, Bin Shan et al.

 
 

We report an atomic scale controllable synthesis of Pd/Pt core shell nanoparticles (NPs) via area-selective atomic layer deposition (ALD) on a modified surface. The method …

 
 
 
 
 
 

Impact of an elastic sphere with an elastic half space revisited: Numerical analysis based on the method of dimensionality reduction

 
 

I. A. Lyashenko, V. L. Popov

 
 

An impact of an elastic sphere with an elastic half space under no-slip conditions (infinitely large coefficient of friction) is studied numerically using the method of …

 
 
 
 
 
 

Carnival or football, is there a real risk for acquiring dengue fever in Brazil during holidays seasons?

 
 

Maíra Aguiar, Filipe Rocha, José Eduardo Marques Pessanha et al.

 
 

More than 600,000 football fans, coming from all over the world, were expected to visit Brazil during the FIFA World Cup 2014. International travel can become a public health …

 
 
 
 
 
 

Surface structure determines dynamic wetting

 
 

Jiayu Wang, Minh Do-Quang, James J. Cannon et al.

 
 

Liquid wetting of a surface is omnipresent in nature and the advance of micro-fabrication and assembly techniques in recent years offers increasing ability to control this …

 
 
 
 
 
 

Observation of coherent oscillation in single-passage Landau-Zener transitions

 
 

Guozhu Sun, Xueda Wen, Ming Gong et al.

 
 

Landau-Zener transition (LZT) has been explored in a variety of physical systems for coherent population transfer between different quantum states. In recent years, there have …

 
 
 
 
 
 

Computational Electromagnetic Analysis of Deformed Nanowires Using the Multilevel Fast Multipole Algorithm

 
 

Akif Yılmaz, Barışcan KaraosmanoÄŸlu, Özgür Ergül

 
 

We consider computational analysis of deformed nanowires and their arrays using a full-wave simulation environment based on integral-equation formulations and the multilevel fast …

 
 
 
 
 
 

Integration of lead-free ferroelectric on HfO2/Si (100) for high performance non-volatile memory applications

 
 

Souvik Kundu, Deepam Maurya, Michael Clavel et al.

 
 

We introduce a novel lead-free ferroelectric thin film (1-x)BaTiO3-xBa(Cu1/3Nb2/3)O3 (x=0.025) (BT-BCN) integrated on to HfO2 buffered Si for non-volatile memory (NVM) …

 
 
 
 
 
 

Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”

 
 

Alexander Golberg, Bote G. Bruinsma, Basak E. Uygun et al.

 
 

Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid tumors ablation, under clinical investigation for cancer therapy. IRE affects only the …

 
 
 
 
 
 

Suppressing Klein tunneling in graphene using a one-dimensional array of localized scatterers

 
 

Jamie D. Walls, Daniel Hadad

 
 

Graphene's unique physical and chemical properties make it an attractive platform for use in micro- and nanoelectronic devices. However, electrostatically controlling the flow of …

 
 
 
 
 
 

Measuring the Refractive Index of Highly Crystalline Monolayer MoS2 with High Confidence

 
 

Hui Zhang, Yaoguang Ma, Yi Wan et al.

 
 

Monolayer molybdenum disulphide (MoS2) has attracted much attention, due to its attractive properties, such as two-dimensional properties, direct bandgap, valley-selective …

 
 
 
 
 
 

Superoscillations without Sidebands: Power-Efficient Sub-Diffraction Imaging with Propagating Waves

 
 

Alex M. H. Wong, George V. Eleftheriades

 
 

A superoscillation wave is a special superposition of propagating electromagnetic (EM) waves which varies with sub-diffraction resolution inside a fixed region. This special …

 
 
 
 
 
 

An Effect of Molecular Motion on Carrier Formation in a Poly(3-hexylthiophene) Film

 
 

Yudai Ogata, Daisuke Kawaguchi, Keiji Tanaka

 
 

Free carriers, polarons (P), in conjugated polymers play a key role in the performance of optoelectronic devices. Here, we present solid evidence that P can be predominantly …

 
 
 
 
 
 

Study of DNA adsorption on mica surfaces using a surface force apparatus

 
 

Yajing Kan, Qiyan Tan, Gensheng Wu et al.

 
 

We report our studies on the adsorption properties of double-stranded DNA molecules on mica surfaces in a confined environment using a surface force apparatus. Specifically, we …

 
 
 
 
 
 

Complex dynamics of a dc glow discharge tube: Experimental modeling and stability diagrams

 
 

Eugenio Pugliese, Riccardo Meucci, Stefano Euzzor et al.

 
 

We report a detailed experimental study of the complex behavior of a dc low-pressure plasma discharge tube of the type commonly used in commercial illuminated signs, in a …

 
 
 
 
 
 

Fermi Level shifting, Charge Transfer and Induced Magnetic Coupling at La0.7Ca0.3MnO3/LaNiO3 Interface

 
 

Xingkun Ning, Zhanjie Wang, Zhidong Zhang

 
 

A large magnetic coupling has been observed at the La0.7Ca0.3MnO3/LaNiO3 (LCMO/LNO) interface. The x-ray photoelectron spectroscopy (XPS) study results show that Fermi level …

 
 
 
 
 
 

Effect of Annealing Treatment on Mechanical Properties of Nanocrystalline α-iron: an Atomistic Study

 
 

Xuhang Tong, Hao Zhang, D. Y. Li

 
 

Claims are often found in the literature that metallic materials can be nanocrystallized by severe plastic deformation (SPD). However, SPD does not generate a well-defined …

 
 
 
 
 
 

Continuously tunable electronic structure of transition metal dichalcogenides superlattices

 
 

Yong-Hong Zhao, Feng Yang, Jian Wang et al.

 
 

Two dimensional transition metal dichalcogenides have very exciting properties for optoelectronic applications. In this work we theoretically investigate and predict that …

 
 
 
 
 
 

Graphene-based active slow surface plasmon polaritons

 
 

Hua Lu, Chao Zeng, Qiming Zhang et al.

 
 

Finding new ways to control and slow down the group velocity of light in media remains a major challenge in the field of optics. For the design of plasmonic slow light …

 
 
 
 
 
 

Role of surface plasmon polaritons and other waves in the radiation of resonant optical dipole antennas

 
 

Hongwei Jia, Haitao Liu, Ying Zhong

 
 

The radiation of an electric dipole emitter can be drastically enhanced if the emitter is placed in the nano-gap of a metallic dipole antenna. By assuming that only surface …

 
 
 
 
 
 

Dispersion management of anisotropic metamirror for super-octave bandwidth polarization conversion

 
 

Yinghui Guo, Yanqin Wang, Mingbo Pu et al.

 
 

Dispersion engineering of metamaterials is critical yet not fully released in applications where broadband and multispectral responses are desirable. Here we propose a strategy …

 
 
 
 
 
 

Facile synthesis of novel graphene sponge for high performance capacitive deionization

 
 

Xingtao Xu, Likun Pan, Yong Liu et al.

 
 

Capacitive deionization (CDI) is an effective desalination technique offering an appropriate route to obtain clean water. In order to obtain excellent CDI performance, a …

 
 
 
 
 
 

Terahertz in-line digital holography of human hepatocellular carcinoma tissue

 
 

Lu Rong, Tatiana Latychevskaia, Chunhai Chen et al.

 
 

Terahertz waves provide a better contrast in imaging soft biomedical tissues than X-rays, and unlike X-rays, they cause no ionisation damage, making them a good option for …

 
 
 
 
 
 

Topological Metal of NaBi with Ultralow Lattice Thermal Conductivity and Electron-phonon Superconductivity

 
 

Ronghan Li, Xiyue Cheng, Qing Xie et al.

 
 

By means of first-principles and ab initio tight-binding calculations, we found that the compound of NaBi is a three-dimensional non-trivial topological metal. Its topological …

 
 
 
 
 
 

Robust magnetic moments on the basal plane of the graphene sheet effectively induced by OH groups

 
 

Tao Tang, Nujiang Tang, Yongping Zheng et al.

 
 

Inducing robust magnetic moments on the basal plane of the graphene sheet is very difficult, and is one of the greatest challenges in the study of physical chemistry of graphene …

 
 
 
 
 
 

Evidence of the hydrogen release mechanism in bulk MgH2

 
 

Kazuhiro Nogita, Xuan Q. Tran, Tomokazu Yamamoto et al.

 
 

Hydrogen has the potential to power much of the modern world with only water as a by-product, but storing hydrogen safely and efficiently in solid form such as magnesium hydride …

 
 
 
 
 
 

Driving a GaAs film to a large-gap topological insulator by tensile strain

 
 

Mingwen Zhao, Xin Chen, Linyang Li et al.

 
 

Search for materials with a large nontrivial band gap is quite crucial for the realization of the devices using quantum spin Hall (QSH) effects. From first-principles …

 
 
 
 
 
 

Topological incommensurate magnetization plateaus in quasi-periodic quantum spin chains

 
 

Hai-Ping Hu, Chen Cheng, Hong-Gang Luo et al.

 
 

Uncovering topologically nontrivial states in nature is an intriguing and important issue in recent years. While most studies are based on the topological band insulators, the …

 
 
 
 
 
 

Quantum speed limits in open systems: Non-Markovian dynamics without rotating-wave approximation

 
 

Zhe Sun, Jing Liu, Jian Ma et al.

 
 

We derive an easily computable quantum speed limit (QSL) time bound for open systems whose initial states can be chosen as either pure or mixed states. Moreover, this QSL time is …

 
 
 
 
 
 

Enhancing robustness of coupled networks under targeted recoveries

 
 

Maoguo Gong, Lijia Ma, Qing Cai et al.

 
 

Coupled networks are extremely fragile because a node failure of a network would trigger a cascade of failures on the entire system. Existing studies mainly focused on the …

 
 
 
 
 
 

Gate Tunable Relativistic Mass and Berry's phase in Topological Insulator Nanoribbon Field Effect Devices

 
 

Luis A. Jauregui, Michael T. Pettes, Leonid P. Rokhinson et al.

 
 

Transport due to spin-helical massless Dirac fermion surface state is of paramount importance to realize various new physical phenomena in topological insulators, ranging from …

 
 
 
 
 
 

Muonium in Stishovite: Implications for the Possible Existence of Neutral Atomic Hydrogen in the Earth's Deep Mantle

 
 

Nobumasa Funamori, Kenji M. Kojima, Daisuke Wakabayashi et al.

 
 

Hydrogen in the Earth's deep interior has been thought to exist as a hydroxyl group in high-pressure minerals. We present Muon Spin Rotation experiments on SiO2 stishovite, which …

 
 
 
 
 
 

A neuro-inspired model-based closed-loop neuroprosthesis for the substitution of a cerebellar learning function in anesthetized rats

 
 

Roni Hogri, Simeon A. Bamford, Aryeh H. Taub et al.

 
 

Neuroprostheses could potentially recover functions lost due to neural damage. Typical neuroprostheses connect an intact brain with the external environment, thus replacing …

 
 
 
 
 
 

Clocking the anisotropic lattice dynamics of multi-walled carbon nanotubes by four-dimensional ultrafast transmission electron microscopy

 
 

Gaolong Cao, Shuaishuai Sun, Zhongwen Li et al.

 
 

Recent advances in the four-dimensional ultrafast transmission electron microscope (4D-UTEM) with combined spatial and temporal resolutions have made it possible to directly …

 
 
 
 
 
 

Tape Transfer Atomization Patterning of Liquid Alloys for Microfluidic Stretchable Wireless Power Transfer

 
 

Seung Hee Jeong, Klas Hjort, Zhigang Wu

 
 

Stretchable electronics offers unsurpassed mechanical compliance on complex or soft surfaces like the human skin and organs. To fully exploit this great advantage, an autonomous …

 
 
 
 
 
 

Dual enhancement of electroluminescence efficiency and operational stability by rapid upconversion of triplet excitons in OLEDs

 
 

Taro Furukawa, Hajime Nakanotani, Munetomo Inoue et al.

 
 

Recently, triplet harvesting via a thermally activated delayed fluorescence (TADF) process has been established as a realistic route for obtaining ultimate internal …

 
 
 
 
 
 

Resilience of hybrid optical angular momentum qubits to turbulence

 
 

Osvaldo Jiménez Farías, Vincenzo D'Ambrosio, Caterina Taballione et al.

 
 

Recent schemes to encode quantum information into the total angular momentum of light, defining rotation-invariant hybrid qubits composed of the polarization and orbital angular …

 
 
 
 
 
 

Role of Co-Vapors in Vapor Deposition Polymerization

 
 

Ji Eun Lee, Younghee Lee, Ki-Jin Ahn et al.

 
 

Polypyrrole (PPy)/cellulose (PPCL) composite papers were fabricated by vapor phase polymerization. Importantly, the vapor-phase deposition of PPy onto cellulose was assisted by …

 
 
 
 
 
 

Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase

 
 

Elena Formoso, Vittorio Limongelli, Michele Parrinello

 
 

Adenylate Kinase (AK) is a signal transducing protein that regulates cellular energy homeostasis balancing between different conformations. An alteration of its activity can lead …

 
 
 
 
 
 

Dependence of structure and temperature for lithium-rich layered-spinel microspheres cathode material of lithium ion batteries

 
 

Di Wang, Ruizhi Yu, Xianyou Wang et al.

 
 

Homogeneous lithium-rich layered-spinel 0.5Li2MnO3·0.5LiMn1/3Ni1/3Co1/3O2 microspheres (~1 μm) are successfully prepared by a solvothermal method and subsequent high-temperature …

 
 
 
 
 
 

Inexpensive Antimony Nanocrystals and Their Composites with Red Phosphorus as High-Performance Anode Materials for Na-ion Batteries

 
 

Marc Walter, Rolf Erni, Maksym V. Kovalenko

 
 

Sodium-ion batteries increasingly become of immense research interest as a potential inexpensive alternative to Lithium-ion batteries. Development of high-energy-density negative …

 
 
 
 
 
 

Quantum anomalous Hall and quantum spin-Hall phases in flattened Bi and Sb bilayers

 
 

Kyung-Hwan Jin, Seung-Hoon Jhi

 
 

Discovery of two-dimensional topological insulator such as Bi bilayer initiates challenges in exploring exotic quantum states in low dimensions. We demonstrate a promising way to …

 
 
 
 
 
 

Chains of Carbon Nanotetrahedra/Nanoribbons

 
 

Hideo Kohno, Takayuki Hasegawa

 
 

Flattening of a carbon nanotube results in the formation of a carbon nanoribbon with well-defined edges. In addition, a switching of the flattening direction by about a right …

 
 
 
 
 
 

Excitation of Multipole Plasmons by Optical Vortex Beams

 
 

Kyosuke Sakai, Kensuke Nomura, Takeaki Yamamoto et al.

 
 

Localized surface plasmon resonance (LSPR) has been shown to exhibit a strong potential for nanoscale electromagnetic field manipulation beyond the diffraction limit. …

 
 
 
 
 
 

Counterfactual quantum-information transfer without transmitting any physical particles

 
 

Qi Guo, Liu-Yong Cheng, Li Chen et al.

 
 

We demonstrate quantum information can be transferred between two distant participants without any physical particles traveling between them. The key procedure of the …

 
 
 
 
 
 

Intrinsic dynamics induce global symmetry in network controllability

 
 

Chen Zhao, Wen-Xu Wang, Yang-Yu Liu et al.

 
 

Controlling complex networked systems to desired states is a key research goal in contemporary science. Despite recent advances in studying the impact of network topology on …

 
 
 
 
 
 

Hierarchical multicolor nano-pixel matrices formed by coordinating luminescent metal ions to a conjugated poly(4′-octyl-2′,6′-bispyrazoyl pyridine) film via contact printing

 
 

Supratim Basak, Md Ahamad Mohiddon, Martin Baumgarten et al.

 
 

We introduce a cost-effective, yet feasible reactive printing approach namely, “coordination chemistry at the conjugated ligand polymer surface”. By using a contact printing …

 
 
 
 
 
 

Worldwide variations in artificial skyglow

 
 

Christopher C. M. Kyba, Kai Pong Tong, Jonathan Bennie et al.

 
 

Despite constituting a widespread and significant environmental change, understanding of artificial nighttime skyglow is extremely limited. Until now, published monitoring …

 
 
 
 
 
 

The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains

 
 

J. L. Perez Velazquez, R. Guevara Erra, M. Rosenblum

 
 

The rhythmic activity observed in nervous systems, in particular in epilepsies and Parkinson's disease, has often been hypothesized to originate from a macroscopic self-sustained …

 
 
 
 
 
 

Anchoring Dipalmitoyl Phosphoethanolamine to Nanoparticles Boosts Cellular Uptake and Fluorine-19 Magnetic Resonance Signal

 
 

Sonia Waiczies, Stefano Lepore, Karl Sydow et al.

 
 

Magnetic resonance (MR) methods to detect and quantify fluorine (19F) nuclei provide the opportunity to study the fate of cellular transplants in vivo. Cells are typically …

 
 
 
 
 
 

Dimensional crossover and cold-atom realization of topological Mott insulators

 
 

Mathias S. Scheurer, Stephan Rachel, Peter P. Orth

 
 

Interacting cold-atomic gases in optical lattices offer an experimental approach to outstanding problems of many body physics. One important example is the interplay of …

 
 
 
 
 
 

Emergence of topological and topological crystalline phases in TlBiS2 and TlSbS2

 
 

Qingyun Zhang, Yingchun Cheng, Udo Schwingenschlögl

 
 

Using first-principles calculations, we investigate the band structure evolution and topological phase transitions in TlBiS2 and TlSbS2 under hydrostatic pressure as well as …

 
 
 
 
 
 

Multi-barrier field-emission behavior in PBTTT thin films at low temperatures

 
 

Evan S. H. Kang, Eunseong Kim

 
 

We investigated the low-temperature transport mechanism for poly[2,5-bis(3-alkylthiophen-2-yl)thieno(3,2-b)thiophene] (PBTTT). The temperature-dependent transport behavior was …

 
 
 
 
 
 

Hybrid luminescence materials assembled by [Ln(DPA)3]3− and mesoporous host through ion-pairing interactions with high quantum efficiencies and long lifetimes

 
 

Qing-Feng Li, Dan Yue, Wei Lu et al.

 
 

A kind of mesoporous hybrid luminescence material was assembled through the ion exchange method between [Ln(DPA)3]3− and ionic liquid functionalized SBA-15. [Ln(DPA)3]3− was …

 
 
 
 
 
 

Hiding scattering layers for noninvasive imaging of hidden objects

 
 

Kedi Wu, Qiluan Cheng, Yile Shi et al.

 
 

The ability to noninvasive image through turbid media has long been a major scientific and technological goal in many disciplines. A breakthrough has been made to observe objects …

 
 
 
 
 
 

Tuning Interior Nanogaps of Double-shelled Au/Ag Nanoboxes for Surface-Enhanced Raman Scattering

 
 

Weiqing Zhang, Mohsen Rahmani, Wenxin Niu et al.

 
 

Double-shelled Au/Ag hollow nanoboxes with precisely controlled interior nanogaps (1 to 16 nm) were synthesized for gap-tunable surface-enhanced Raman scattering (SERS). The …

 
 
 
 
 
 

Photoresponse dynamics in amorphous-LaAlO3/SrTiO3 interfaces

 
 

Emiliano Di Gennaro, Ubaldo Coscia, Giuseppina Ambrosone et al.

 
 

The time-resolved photoconductance of amorphous and crystalline LaAlO3/SrTiO3 interfaces, both hosting an interfacial 2-dimensional electron gas, is investigated under …

 
 
 
 
 
 

Efficient Organic Photovoltaics Utilizing Nanoscale Heterojunctions in Sequentially Deposited Polymer/fullerene Bilayer

 
 

Jeesoo Seok, Tae Joo Shin, Sungmin Park et al.

 
 

A highly efficient sequentially deposited bilayer (SD-bilayer) of polymer/fullerene organic photovoltaic (OPV) device is developed via the solution process. Herein, we resolve …

 
 
 
 
 
 

Agent-based model with multi-level herding for complex financial systems

 
 

Jun-Jie Chen, Lei Tan, Bo Zheng

 
 

In complex financial systems, the sector structure and volatility clustering are respectively important features of the spatial and temporal correlations. However, the …

 
 
 
 
 
 

Hierarchical Auxetic Mechanical Metamaterials

 
 

Ruben Gatt, Luke Mizzi, Joseph I. Azzopardi et al.

 
 

Auxetic mechanical metamaterials are engineered systems that exhibit the unusual macroscopic property of a negative Poisson's ratio due to sub-unit structure rather than chemical …

 
 
 
 
 
 

Microscopic Receding Contact Line Dynamics on Pillar and Irregular Superhydrophobic Surfaces

 
 

Yong Han Yeong, Athanasios Milionis, Eric Loth et al.

 
 

Receding angles have been shown to have great significance when designing a superhydrophobic surface for applications involving self-cleaning. Although apparent receding angles …

 
 
 
 
 
 

Minimising hydrogen sulphide generation during steam assisted production of heavy oil

 
 

Wren Montgomery, Mark A. Sephton, Jonathan S. Watson et al.

 
 

The majority of global petroleum is in the form of highly viscous heavy oil. Traditionally heavy oil in sands at shallow depths is accessed by large scale mining activities. …

 
 
 
 
 
 

A high-resolution 2D J-resolved NMR detection technique for metabolite analyses of biological samples

 
 

Yuqing Huang, Zhiyong Zhang, Hao Chen et al.

 
 

NMR spectroscopy is a commonly used technique for metabolite analyses. Due to the observed macroscopic magnetic susceptibility in biological tissues, current NMR acquisitions in …

 
 
 
 
 
 

Realizing and characterizing chiral photon flow in a circuit quantum electrodynamics necklace

 
 

Yan-Pu Wang, Wei Wang, Zheng-Yuan Xue et al.

 
 

Gauge theory plays the central role in modern physics. Here we propose a scheme of implementing artificial Abelian gauge fields via the parametric conversion method in a necklace …

 
 
 
 
 
 

A simple method for tuning the glass transition process in inorganic phosphate glasses

 
 

René Fulchiron, Imane Belyamani, Joshua U. Otaigbe et al.

 
 

The physical modification of glass transition temperature (Tg) and properties of materials via blending is a common practice in industry and academia and has a large economic …

 
 
 
 
 
 

A biopolymer-like metal enabled hybrid material with exceptional mechanical prowess

 
 

Junsong Zhang, Lishan Cui, Daqiang Jiang et al.

 
 

The design principles for naturally occurring biological materials have inspired us to develop next-generation engineering materials with remarkable performance. Nacre, commonly …

 
 
 
 
 
 

Octahedral faceted Si nanoparticles as optical traps with enormous yield amplification

 
 

Giovanni Mannino, Alessandra Alberti, Rosa Ruggeri et al.

 
 

We describe a method for the creation of an efficient optical scatter trap by using fully crystalline octahedral Silicon nanoparticles (Si-NPs) of approximately 100 nanometres in …

 
 
 
 
 
 

n and p type character of single molecule diodes

 
 

Vinícius Claudio Zoldan, Ricardo Faccio, André Avelino Pasa

 
 

Looking for single molecule electronic devices, we have investigated the charge transport properties of individual tetra-phenylporphyrin molecules on different substrates by …

 
 
 
 
 
 

Comparison of growth texture in round Bi2212 and flat Bi2223 wires and its relation to high critical current density development

 
 

F. Kametani, J. Jiang, M. Matras et al.

 
 

Why Bi2Sr2CaCu2Ox (Bi2212) allows high critical current density Jc in round wires rather than only in the anisotropic tape form demanded by all other high temperature …

 
 
 
 
 
 

Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection

 
 

A. Christy Wyckoff, Nathan Galloway, Crystal Meyerett-Reid et al.

 
 

Prions are unique infectious agents that replicate without a genome and cause neurodegenerative diseases that include chronic wasting disease (CWD) of cervids. …

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

A Novel Protocol for Model Calibration in Biological Wastewater Treatment

 
 

Ao Zhu, Jianhua Guo, Bing-Jie Ni et al.

 
 

Activated sludge models (ASMs) have been widely used for process design, operation and optimization in wastewater treatment plants. However, it is still a challenge to achieve an …

 
 
 
 
 
 

Temperature and solids retention time control microbial population dynamics and volatile fatty acid production in replicated anaerobic digesters

 
 

Inka Vanwonterghem, Paul D. Jensen, Korneel Rabaey et al.

 
 

Anaerobic digestion is a widely used technology for waste stabilization and generation of biogas, and has recently emerged as a potentially important process for the production …

 
 
 
 
 
 

The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure

 
 

Zhenhua Shi, Hui Yu, Yongyan Sun et al.

 
 

A literal mountain of documentation generated in the past five decades showing unmistakable health hazards associated with extremely low-frequency electromagnetic fields …

 
 
 
 
 
 

Muonium in Stishovite: Implications for the Possible Existence of Neutral Atomic Hydrogen in the Earth's Deep Mantle

 
 

Nobumasa Funamori, Kenji M. Kojima, Daisuke Wakabayashi et al.

 
 

Hydrogen in the Earth's deep interior has been thought to exist as a hydroxyl group in high-pressure minerals. We present Muon Spin Rotation experiments on SiO2 stishovite, which …

 
 
 
 
 
 

Pangea breakup and northward drift of the Indian subcontinent reproduced by a numerical model of mantle convection

 
 

Masaki Yoshida, Yozo Hamano

 
 

Since around 200 Ma, the most notable event in the process of the breakup of Pangea has been the high speed (up to 20 cm yr−1) of the northward drift of the Indian subcontinent. …

 
 
 
 
 
 

Future projection of radiocesium flux to the ocean from the largest river impacted by Fukushima Daiichi Nuclear Power Plant

 
 

Mochamad Adhiraga Pratama, Minoru Yoneda, Yoko Shimada et al.

 
 

Following the initial fall out from Fukushima Dai-ichi Nuclear Power Plant (FDNPP), a significant amount of radiocesium has been discharged from Abukuma River into the Pacific …

 
 
 
 
 
 

Estimation of the parameters of ETAS models by Simulated Annealing

 
 

Anna Maria Lombardi

 
 

This paper proposes a new algorithm to estimate the maximum likelihood parameters of an Epidemic Type Aftershock Sequences (ETAS) model. It is based on Simulated Annealing, a …

 
 
 
 
 
 

Worldwide variations in artificial skyglow

 
 

Christopher C. M. Kyba, Kai Pong Tong, Jonathan Bennie et al.

 
 

Despite constituting a widespread and significant environmental change, understanding of artificial nighttime skyglow is extremely limited. Until now, published monitoring …

 
 
 
 
 
 

Climate change as an unexpected co-factor promoting coral eating seastar (Acanthaster planci) outbreaks

 
 

S. Uthicke, M. Logan, M. Liddy et al.

 
 

Coral reefs face a crisis due to local and global anthropogenic stressors. A large proportion of the ~50% coral loss on the Great Barrier Reef has been attributed to outbreaks of …

 
 
 
 
 
 

Minimising hydrogen sulphide generation during steam assisted production of heavy oil

 
 

Wren Montgomery, Mark A. Sephton, Jonathan S. Watson et al.

 
 

The majority of global petroleum is in the form of highly viscous heavy oil. Traditionally heavy oil in sands at shallow depths is accessed by large scale mining activities. …

 
 
 
 
 
 

Strong effects of ionizing radiation from Chernobyl on mutation rates

 
 

Anders Pape Møller, Timothy A. Mousseau

 
 

In this paper we use a meta-analysis to examine the relationship between radiation and mutation rates in Chernobyl across 45 published studies, covering 30 species. Overall …

 
 
 
 
 
 

Earth's Phosphides in Levant and insights into the source of Archean prebiotic phosphorus

 
 

Sergey N. Britvin, Michail N. Murashko, Yevgeny Vapnik et al.

 
 

Natural phosphides - the minerals containing phosphorus in a redox state lower than zero – are common constituents of meteorites but virtually unknown on the Earth. Herein we …

 
 
 
 
 
 

Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection

 
 

A. Christy Wyckoff, Nathan Galloway, Crystal Meyerett-Reid et al.

 
 

Prions are unique infectious agents that replicate without a genome and cause neurodegenerative diseases that include chronic wasting disease (CWD) of cervids. …

 
 
 
 
 
 
 
Health Sciences top
 
 
 
 
 
 
 

Neurokinin B Administration Induces Hot Flushes in Women

 
 

Channa N. Jayasena, Alexander N. Comninos, Evgenia Stefanopoulou et al.

 
 

Neurokinin B (NKB) is a hypothalamic neuropeptide binding preferentially to the neurokinin 3 receptor. Expression of the gene encoding NKB is elevated in postmenopausal women. …

 
 
 
 
 
 

Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer

 
 

Juan Tan, Chen-Yang Yu, Zhen-Hua Wang et al.

 
 

Members of the inositol phosphate metabolism pathway regulate cell proliferation, migration and phosphatidylinositol-3-kinase (PI3K)/Akt signaling, and are frequently …

 
 
 
 
 
 

Fermented RhizomaAtractylodis Macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats

 
 

Jing-Hua Wang, Shambhunath Bose, Hyung-Gu Kim et al.

 
 

Accumulating evidence suggests the anti-inflammatory and anti-obesity activities of Rhizoma Atractylodis Macrocephalae (RAM). Here, we evaluated the anti-obesity impact of …

 
 
 
 
 
 

Carnival or football, is there a real risk for acquiring dengue fever in Brazil during holidays seasons?

 
 

Maíra Aguiar, Filipe Rocha, José Eduardo Marques Pessanha et al.

 
 

More than 600,000 football fans, coming from all over the world, were expected to visit Brazil during the FIFA World Cup 2014. International travel can become a public health …

 
 
 
 
 
 

Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”

 
 

Alexander Golberg, Bote G. Bruinsma, Basak E. Uygun et al.

 
 

Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid tumors ablation, under clinical investigation for cancer therapy. IRE affects only the …

 
 
 
 
 
 

hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold

 
 

Ruodan Xu, Mehmet Berat Taskin, Marina Rubert et al.

 
 

Fibroblasts are ubiquitous cells that constitute the stroma of virtually all tissues and play vital roles in homeostasis. The poor innate healing capacity of fibroblastic tissues …

 
 
 
 
 
 

The Energy Metabolism in Caenorhabditis elegans under The Extremely Low-Frequency Electromagnetic Field Exposure

 
 

Zhenhua Shi, Hui Yu, Yongyan Sun et al.

 
 

A literal mountain of documentation generated in the past five decades showing unmistakable health hazards associated with extremely low-frequency electromagnetic fields …

 
 
 
 
 
 

Simultaneous bile duct and portal vein ligation induces faster atrophy/hypertrophy complex than portal vein ligation: role of bile acids

 
 

Weizheng Ren, Geng Chen, Xiaofeng Wang et al.

 
 

Portal vein ligation (PVL) induces atrophy/hypertrophy complex (AHC). We hypothesised that simultaneous bile duct and portal vein ligation (BPL) might induce proper bile acid …

 
 
 
 
 
 

How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila

 
 

R. Faville, B. Kottler, G. J. Goodhill et al.

 
 

The fruitfly, Drosophila melanogaster, has become a critical model system for investigating sleep functions. Most studies use duration of inactivity to measure sleep. However, a …

 
 
 
 
 
 

Association between levonorgestrel emergency contraception and the risk of ectopic pregnancy: a multicenter case-control study

 
 

Jian Zhang, Cheng Li, Wei-Hong Zhao et al.

 
 

Cases of ectopic pregnancy (EP) following levonorgestrel emergency contraception (LNG-EC) failure have been reported continuously, but whether there is an association between EP …

 
 
 
 
 
 

CORRIGENDUM: A Comparative Study of Fast-Track Versus Conventional Surgery in Patients Undergoing Laparoscopic Radical Cystectomy and Ileal Conduit Diversion: Chinese Experience

 
 

Xiao Guan, Longfei Liu, Xiang Lei et al.

 
 

 
 
 
 
 
 

The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains

 
 

J. L. Perez Velazquez, R. Guevara Erra, M. Rosenblum

 
 

The rhythmic activity observed in nervous systems, in particular in epilepsies and Parkinson's disease, has often been hypothesized to originate from a macroscopic self-sustained …

 
 
 
 
 
 

SIRT2 is involved in the modulation of depressive behaviors

 
 

Rui Liu, Wei Dang, Ying Du et al.

 
 

Exposure to chronic stress produces negative effects on mood and hippocampus-dependent memory formation. SIRT2 alteration has been reported in mood disorders; however, the role …

 
 
 
 
 
 

Anchoring Dipalmitoyl Phosphoethanolamine to Nanoparticles Boosts Cellular Uptake and Fluorine-19 Magnetic Resonance Signal

 
 

Sonia Waiczies, Stefano Lepore, Karl Sydow et al.

 
 

Magnetic resonance (MR) methods to detect and quantify fluorine (19F) nuclei provide the opportunity to study the fate of cellular transplants in vivo. Cells are typically …

 
 
 
 
 
 

ERRATUM: Genomic Analyses across Six Cancer Types Identify Basal-like Breast Cancer as a Unique Molecular Entity

 
 

Aleix Prat, Barbara Adamo, Cheng Fan et al.

 
 

 
 
 
 
 
 

Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

 
 

Lichan Tao, Sutong Shen, Siyi Fu et al.

 
 

In a multicenter randomized double-blind study we demonstrated that Qiliqiangxin (QLQX), a traditional Chinese medicine, had a protective effect in heart failure patients. …

 
 
 
 
 
 

A Green Strategy to Prepare Metal Oxide Superstructure from Metal-Organic Frameworks

 
 

Yonghai Song, Xia Li, Changting Wei et al.

 
 

Metal or metal oxides with diverse superstructures have become one of the most promising functional materials in sensor, catalysis, energy conversion, etc. In this work, a novel …

 
 
 
 
 
 

Down-Regulation of Human Enteric Antimicrobial Peptides by NOD2 during Differentiation of the Paneth Cell Lineage

 
 

Gao Tan, Run-hua Li, Chen Li et al.

 
 

Ileal Crohn's disease (CD) arising from the alteration of intestinal homeostasis is characterized by two features, namely a decrease in Paneth cell-produced antimicrobial …

 
 
 
 
 
 

Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain

 
 

Jennifer Fazzari, Hanxin Lin, Cecilia Murphy et al.

 
 

Glutamate is an important signaling molecule in a wide variety of tissues. Aberrant glutamatergic signaling disrupts normal tissue homeostasis and induces several disruptive …

 
 
 
 
 
 

The Genetics of POAG in Black South Africans: A Candidate Gene Association Study

 
 

Susan E. I. Williams, Trevor R. Carmichael, R. Rand Allingham et al.

 
 

Multiple loci have been associated with either primary open angle glaucoma (POAG) or heritable ocular quantitative traits associated with this condition. This study examined the …

 
 
 
 
 
 

Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells

 
 

Aeyung Kim, Minju Im, Jin Yeul Ma

 
 

Remotiflori radix is the root of Mosidae, which has long been used as a traditional medicine to treat chills, fever, and phlegm discharge. The ethanol extract of Mosidae leaves …

 
 
 
 
 
 

Sirtinol Inhibits Neutrophil Elastase Activity and Attenuates Lipopolysaccharide-Mediated Acute Lung Injury in Mice

 
 

Yung-Fong Tsai, Huang-Ping Yu, Wen-Yi Chang et al.

 
 

Enhanced activity of neutrophil elastase leads to a protease–antiprotease imbalance, and plays an essential pathogenic role in acute lung injury (ALI) and acute respiratory …

 
 
 
 
 
 

Transferable neuronal mini-cultures to accelerate screening in primary and induced pluripotent stem cell-derived neurons

 
 

Mark Niedringhaus, Raluca Dumitru, Angela M. Mabb et al.

 
 

The effort and cost of obtaining neurons for large-scale screens has limited drug discovery in neuroscience. To overcome these obstacles, we fabricated arrays of releasable …

 
 
 
 
 
 

Extensive load of somatic CNVs in the human placenta

 
 

Laura Kasak, Kristiina Rull, Pille Vaas et al.

 
 

Placenta is a temporary, but indispensable organ in mammalian pregnancy. From its basic nature, it exhibits highly invasive tumour-like properties facilitating effective …

 
 
 
 
 
 

Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis

 
 

Jie Tian, Chuan Tian, Yuehe Ding et al.

 
 

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurologic disorder caused by ATTCT expansion in the ATXN10 gene. Previous investigations have identified that …

 
 
 
 
 
 

FGF23 neutralization improves bone quality and osseointegration of titanium implants in chronic kidney disease mice

 
 

Ningyuan Sun, Yuchen Guo, Weiqing Liu et al.

 
 

Chronic kidney disease (CKD) is a worldwide health problem. Serum levels of FGF23, a phosphaturic hormone, increase at the earliest stages of CKD, and have been found to be …

 
 
 
 
 
 

Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines

 
 

Benoit Briard, Perrine Bomme, Beatrix E. Lechner et al.

 
 

The opportunistic fungal pathogen Aspergillus fumigatus is increasingly found as a coinfecting agent along with Pseudomonas aeruginosa in cystic fibrosis patients. Amongst the …

 
 
 
 
 
 

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

 
 

Chouyang Li, Simin Rezania, Sarah Kammerer et al.

 
 

Mechanical interaction between cells – specifically distortion of tensional homeostasis-emerged as an important aspect of breast cancer genesis and progression. We investigated …

 
 
 
 
 
 
 
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