Scientific Reports Table of Contents e-alert: 28 April 2015

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28 April 2015      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports         1st Nature Immunology - Cellular & Molecular Immunology Joint Conference: Inflammation, Stress and Immune Homeostasis June 17-19, 2015 | The Swan Lake Hotel, Hefei, China  Register Now!          Jump to the content that matters to you ▼ Biological Sciences   ▼ Chemical Sciences   ▼ Physical Sciences   ▼ Earth & Environmental Sciences   ▼ Health Sciences               Biological Sciences ▲ top               Fluorescence-Activated Cell Sorting Analysis of Heterotypic Cell-in-Cell Structures ▶     Meifang He, Hongyan Huang, Manna Wang et al.     Cell-in-cell structures (CICs), characterized by the presence of one or more viable cells inside another one, were recently found important player in development, immune …             Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications ▶     Daniel M. Czajkowsky, Jan Terje Andersen, Anja Fuchs et al.     The remarkable clinical success of Fc-fusion proteins has driven intense investigation for even more potent replacements. Using quality-by-design (QbD) approaches, we generated …             Nucleotide Sequence-Homology-Independent Breakdown of Transgenic Resistance by More Virulent Virus Strains and a Potential Solution ▶     Yi-Jung Kung, Bang-Jau You, Joseph A. J. Raja et al.     Controlling plant viruses by genetic engineering, including the globally important Papaya ringspot virus (PRSV), mainly involves coat protein (CP) gene mediated resistance via …             FOXO3 variants are beneficial for longevity in Southern Chinese living in the Red River Basin: A case-control study and meta-analysis ▶     Liang Sun, Caiyou Hu, Chenguang Zheng et al.     Forkhead box class O (FOXO) transcription factors play a crucial role in longevity across species. Several polymorphisms in FOXO3 were previously reported to be associated with …             Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative) ▶     M. Fernanda Lima-Costa, Laura C. Rodrigues, Maurício L. Barreto et al.     Brazil never had segregation laws defining membership of an ethnoracial group. Thus, the composition of the Brazilian population is mixed, and its ethnoracial classification is …             Chemical proteomic identification of T-plastin as a novel host cell response factor in HCV infection ▶     Young-Hwa Yoo, JiHyeon Yun, Chang No Yoon et al.     Hepatitis C virus (HCV) infection is the leading cause of chronic liver disease that currently affects at least 170 million people worldwide. Although significant efforts have …             From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks ▶     Susanna Bosi, Rossana Rauti, Jummi Laishram et al.     To recreate in vitro 3D neuronal circuits will ultimately increase the relevance of results from cultured to whole-brain networks and will promote enabling technologies for …             A sensitive label–free amperometric immunosensor for alpha-fetoprotein based on gold nanorods with different aspect ratio ▶     Chunyang Zhou, Dali Liu, Lin Xu et al.     A simple and accurate label–free amperometric immunosensor for α–fetoprotein (AFP) detection is developed based on gold nanorods (GNRs) with different aspect ratio and compared …             Neuroreceptor Activation by Vibration-Assisted Tunneling ▶     Ross D. Hoehn, David Nichols, Hartmut Neven et al.     G protein-coupled receptors (GPCRs) constitute a large family of receptor proteins that sense molecular signals on the exterior of a cell and activate signal transduction …             Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging ▶     Yanyan Fan, Helin Liu, Rongcheng Han et al.     Materials possessing high two photon absorption (TPA) are highly desirable for a range of fields, such as three-dimensional data storage, TP microscopy (TPM) and photodynamic …             Synergistic Protection of N-Acetylcysteine and Ascorbic Acid 2-Phosphate on Human Mesenchymal Stem cells Against Mitoptosis, Necroptosis and Apoptosis ▶     Chia-Jung Li, Li-Yi Sun, Cheng-Yoong Pang     Human mesenchymal stem cells (hMSCs) contribute to ischemic tissue repair, regeneration, and possess ability to self-renew. However, poor viability of transplanted hMSCs within …             Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence ▶     Putty-Reddy Sudhir, Shiu-Ting Lin, Chien Chia-Wen et al.     Identification and functional analysis of genes from genetically altered chromosomal regions would suggest new molecular targets for cancer diagnosis and treatment. Here we …             Ddx1 knockout results in transgenerational wild-type lethality in mice ▶     Matthew R. Hildebrandt, Devon R. Germain, Elizabeth A. Monckton et al.     DEAD box 1 (DDX1) is a member of the DEAD box family of RNA helicases which are involved in all aspects of RNA metabolism. DDX1 has been implicated in a variety of biological …             MicroRNA transcriptomes of distinct human NK cell populations identify miR-362-5p as an essential regulator of NK cell function ▶     Fang Ni, Chuang Guo, Rui Sun et al.     Natural killer (NK) cells are critical effectors in the immune response against malignancy and infection, and microRNAs (miRNAs) play important roles in NK cell biology. Here we …             Droplet-interface-bilayer assays in microfluidic passive networks ▶     Bárbara Schlicht, Michele Zagnoni     Basic biophysical studies and pharmacological processes can be investigated by mimicking the intracellular and extracellular environments across an artificial cell membrane …             An Ordovician variation on Burgess Shale-type biotas ▶     Joseph P. Botting, Lucy A. Muir, Naomi Jordan et al.     The Cambrian Burgess Shale-type biotas form a globally consistent ecosystem, usually dominated by arthropods. Elements of these communities continued into the Early Ordovician at …             A modelling methodology to assess the effect of insect pest control on agro-ecosystems ▶     Nian-Feng Wan, Xiang-Yun Ji, Jie-Xian Jiang et al.     The extensive use of chemical pesticides for pest management in agricultural systems can entail risks to the complex ecosystems consisting of economic, ecological and social …             Association of CD8+ T lymphocyte repertoire spreading with the severity of DRESS syndrome ▶     Jun Niu, Qingzhu Jia, Qingshan Ni et al.     T-cell receptor (TCR)-mediated cross-recognition is a major mechanism in the pathogenesis of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, the …             Mechanistic Insights into Elastin Degradation by Pseudolysin, the Major Virulence Factor of the Opportunistic Pathogen Pseudomonas aeruginosa ▶     Jie Yang, Hui-Lin Zhao, Li-Yuan Ran et al.     Pseudolysin is the most abundant protease secreted by Pseudomonas aeruginosa and is the major extracellular virulence factor of this opportunistic human pathogen. Pseudolysin …             Deciphering the Venomic Transcriptome of Killer-Wasp Vespa velutina ▶     Zhirui Liu, Shuanggang Chen, You Zhou et al.     Wasp stings have been arising to be a severe public health problem in China in recent years. However, molecular information about lethal or toxic factors in wasp venom is …             Antibacterial activity of silver-killed bacteria: the "zombies" effect ▶     Racheli Ben-Knaz Wakshlak, Rami Pedahzur, David Avnir     We report a previously unrecognized mechanism for the prolonged action of biocidal agents, which we denote as the zombies effect: biocidally-killed bacteria are capable of killing …             Illusory ownership of an invisible body reduces autonomic and subjective social anxiety responses ▶     Arvid Guterstam, Zakaryah Abdulkarim, H. Henrik Ehrsson     What is it like to be invisible? This question has long fascinated man and has been the central theme of many classic literary works. Recent advances in materials science suggest …             Oxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic system ▶     Xuexia Lin, Qiushui Chen, Wu Liu et al.     In this work, we report an integrated microfluidic device for cell co-culture under different concentrations of oxygen, in which the secreted protein VEGF165 was on-line …             Development of a 3D printer using scanning projection stereolithography ▶     Michael P. Lee, Geoffrey J. T. Cooper, Trevor Hinkley et al.     We have developed a system for the rapid fabrication of low cost 3D devices and systems in the laboratory with micro-scale features yet cm-scale objects. Our system is inspired by …             Association of vitamin C, vitamin D, vitamin E and risk of bladder cancer: a dose-response meta-analysis ▶     Fuqiang Chen, Qingshu Li, Yang Yu et al.     A dose-response meta-analysis was conducted to assess the association of vitamin C, D, E with risk of bladder cancer. Pertinent studies were identified in PubMed and Embase. The …             Red Queen dynamics in multi-host and multi-parasite interaction system ▶     Jomar F. Rabajante, Jerrold M. Tubay, Takashi Uehara et al.     In host-parasite systems, dominant host types are expected to be eventually replaced by other hosts due to the elevated potency of their specific parasites. This leads to changes …             Variations in the non-coding transcriptome as a driver of inter-strain divergence and physiological adaptation in bacteria ▶     Matthias Kopf, Stephan Klähn, Ingeborg Scholz et al.     In all studied organisms, a substantial portion of the transcriptome consists of non-coding RNAs that frequently execute regulatory functions. Here, we have compared the primary …             Prognostic value of serum cytokeratin 19 fragments (Cyfra 21-1) in patients with non-small cell lung cancer ▶     Youtao Xu, Lei Xu, Mantang Qiu et al.     The role of serum CYFRA 21-1 level in patients with non-small cell lung cancer (NSCLC) remains to be defined. To re-evaluate the impact of serum CYFRA 21-1 in NSCLC survival, we …             Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation ▶     Yejing Weng, Zhigang Sui, Hao Jiang et al.     Due to the important roles of N-glycoproteins in various biological processes, the global N-glycoproteome analysis has been paid much attention. However, by current strategies for …             Hypothermic temperature effects on organ survival and restoration ▶     Jun Ishikawa, Masamitsu Oshima, Fumitaka Iwasaki et al.     A three-dimensional multicellular organism maintains the biological functions of life support by using the blood circulation to transport oxygen and nutrients and to regulate body …             Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing ▶     Ayumi Tanimura, Minako Kikukawa, Shino Yamaguchi et al.     Consolidated bioprocessing (CBP), which integrates enzyme production, saccharification and fermentation into a one-step process, is a promising strategy for cost-effective ethanol …             NMR spectroscopy reveals the presence and association of lipids and keratin in adhesive gecko setae ▶     Dharamdeep Jain, Alyssa Y. Stark, Peter H. Niewiarowski et al.     Lipid and protein aggregates are one of the fundamental materials of biological systems. Examples include cell membranes, insect cuticle, vertebrate epidermis, feathers, hair and …             Functional Optical Coherence Tomography Enables In Vivo Physiological Assessment of Retinal Rod and Cone Photoreceptors ▶     Qiuxiang Zhang, Rongwen Lu, Benquan Wang et al.     Transient intrinsic optical signal (IOS) changes have been observed in retinal photoreceptors, suggesting a unique biomarker for eye disease detection. However, clinical …             The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells ▶     Basudev Chowdhury, Andrew McGovern, Yi Cui et al.     The USFDA approved “epigenetic drug”, Decitabine, exerts its effect by hypomethylating DNA, demonstrating the pivotal role aberrant genome-wide DNA methylation patterns play in …             Dynamic Distribution of the Gut Microbiota and the Relationship with Apparent Crude Fiber Digestibility and Growth Stages in Pigs ▶     Qing Niu, Pinghua Li, Shuaishuai Hao et al.     The gut microbiota plays an important role in nutrient digestibility in animals. To examine changes in the pig gut microbiota across growth stages and its effects on nutrient …             Structural basis for cooperative oxygen binding and bracelet-assisted assembly of Lumbricus terrestris hemoglobin ▶     Wei-Ting Chen, Yu-Chuen Chen, Horng-Huei Liou et al.     The iron-containing hemoglobins (Hbs) are essential proteins to serve as oxygen transporters in the blood. Among various kinds of Hbs, the earthworm Hbs are the champions in …             Effects of substrate conductivity on cell morphogenesis and proliferation using tailored, atomic layer deposition-grown ZnO thin films ▶     Won Jin Choi, Jongjin Jung, Sujin Lee et al.     We demonstrate that ZnO films grown by atomic layer deposition (ALD) can be employed as a substrate to explore the effects of electrical conductivity on cell adhesion, …             Yeast nitrogen utilization in the phyllosphere during plant lifespan under regulation of autophagy ▶     Kosuke Shiraishi, Masahide Oku, Kosuke Kawaguchi et al.     Recently, microbe-plant interactions at the above-ground parts have attracted great attention. Here we describe nitrogen metabolism and regulation of autophagy in the …             Segregation of information about emotional arousal and valence in horse whinnies ▶     Elodie F. Briefer, Anne-Laure Maigrot, Roi Mandel et al.     Studying vocal correlates of emotions is important to provide a better understanding of the evolution of emotion expression through cross-species comparisons. Emotions are …             Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin ▶     King Chi Chan, Lai Sheung Chan, Joseph Chok Yan Ip et al.     Nasopharyngeal carcinoma (NPC) is an EBV-associated epithelial malignancy prevalent in southern China. Presence of treatment-resistant cancer stem cells (CSC) may associate with …             Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells ▶     Simona Daniele, Barbara Costa, Elisa Zappelli et al.     The poor prognosis of Glioblastoma Multiforme (GBM) is due to a high resistance to conventional treatments and to the presence of a subpopulation of glioma stem cells (GSCs). …             Recombinant Mutated Human TNF in Combination with Chemotherapy for Stage IIIB/IV Non-Small Cell Lung Cancer: A Randomized, Phase III Study ▶     Xiaowen Ma, Yang Song, Kuo Zhang et al.     Tumor necrosis factor (TNF), an anti-angiogenic agent in cancer treatment, is limited to isolated limb perfusion due to systemic toxicities. We previously prepared a TNF mutant …             Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat ▶     Hemmings Wu, Hartwin Ghekiere, Dorien Beeckmans et al.     Conventional deep brain stimulation (DBS) applies constant electrical stimulation to specific brain regions to treat neurological disorders. Closed-loop DBS with real-time …                 npj Quantum Information An online open access journal providing a platform for the latest important research on quantum information, including quantum computing, quantum communications and quantum information theory. The Journal is now open for submissions.  Explore the benefits of submitting your next research article.         Chemical Sciences ▲ top               Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging ▶     Yanyan Fan, Helin Liu, Rongcheng Han et al.     Materials possessing high two photon absorption (TPA) are highly desirable for a range of fields, such as three-dimensional data storage, TP microscopy (TPM) and photodynamic …             Antibacterial activity of silver-killed bacteria: the "zombies" effect ▶     Racheli Ben-Knaz Wakshlak, Rami Pedahzur, David Avnir     We report a previously unrecognized mechanism for the prolonged action of biocidal agents, which we denote as the zombies effect: biocidally-killed bacteria are capable of killing …             Development of a 3D printer using scanning projection stereolithography ▶     Michael P. Lee, Geoffrey J. T. Cooper, Trevor Hinkley et al.     We have developed a system for the rapid fabrication of low cost 3D devices and systems in the laboratory with micro-scale features yet cm-scale objects. Our system is inspired by …             Temperature Dependence of Electric Transport in Few-layer Graphene under Large Charge Doping Induced by Electrochemical Gating ▶     R. S. Gonnelli, F. Paolucci, E. Piatti et al.     The temperature dependence of electric transport properties of single-layer and few-layer graphene at large charge doping is of great interest both for the study of the scattering …             Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation ▶     Yejing Weng, Zhigang Sui, Hao Jiang et al.     Due to the important roles of N-glycoproteins in various biological processes, the global N-glycoproteome analysis has been paid much attention. However, by current strategies for …             A Pure Inorganic ZnO-Co3O4 Overlapped Membrane for Efficient Oil/Water Emulsions Separation ▶     Na Liu, Xin Lin, Weifeng Zhang et al.     The earth's environmental problems, especially for water remediation, need effective methods to solve. Materials with special wettability are developed for the separation of …             The effect of ionic strength on oil adhesion in sandstone – the search for the low salinity mechanism ▶     E. Hilner, M. P. Andersson, T. Hassenkam et al.     Core flood and field tests have demonstrated that decreasing injection water salinity increases oil recovery from sandstone reservoirs. However, the microscopic mechanism behind …             Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18 ▶     Kerstin Sander, Thibault Gendron, Elena Yiannaki et al.     Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers …             Cell voltage versus electrode potential range in aqueous supercapacitors ▶     Zengxin Dai, Chuang Peng, Jung Hoon Chae et al.     Supercapacitors with aqueous electrolytes and nanostructured composite electrodes are attractive because of their high charging-discharging speed, long cycle life, low …                 nature.com webcasts   Nature Publishing Group presents a custom webcast on: Innovations in the microbiome   Date: May 13, 2015 Time: 8am PDT / 11am EDT / 4pm BST / 5pm CEST   Register for the webcast and live Q & A session.    Access the accompanying Innovations In publication free online.   Sponsored by: Nestlé Research Centre         Physical Sciences ▲ top               Tunable quantum interference in a 3D integrated circuit ▶     Zachary Chaboyer, Thomas Meany, L. G. Helt et al.     Integrated photonics promises solutions to questions of stability, complexity, and size in quantum optics. Advances in tunable and non-planar integrated platforms, such as …             Strategical incoherence regulates cooperation in social dilemmas on multiplex networks ▶     Joan T. Matamalas, Julia Poncela-Casasnovas, Sergio Gómez et al.     Cooperation is a very common, yet not fully-understood phenomenon in natural and human systems. The introduction of a network within the population is known to affect the outcome …             Ultra-Small, High-Frequency, and Substrate-Immune Microtube Inductors Transformed from 2D to 3D ▶     Xin Yu, Wen Huang, Moyang Li et al.     Monolithic on-chip inductors are key passive devices in radio frequency integrated circuits (RFICs). Currently, 70–80% of the on-wafer area of most RFIC chips is occupied by the …             Enhanced Crystallinity of Epitaxial Graphene Grown on Hexagonal SiC Surface with Molybdenum Plate Capping ▶     Han Byul Jin, Youngeun Jeon, Sungchul Jung et al.     The crystallinity of epitaxial graphene (EG) grown on a Hexagonal-SiC substrate is found to be enhanced greatly by capping the substrate with a molybdenum plate (Mo-plate) during …             Ultrafast optical excitation of magnetic skyrmions ▶     N. Ogawa, S. Seki, Y. Tokura     Magnetic skyrmions in an insulating chiral magnet Cu2OSeO3 were studied by all-optical spin wave spectroscopy. The spins in the conical and skyrmion phases were excited by the …             Anisotropic modulation of magnetic properties and the memory effect in a wide-band (011)-Pr0.7Sr0.3MnO3/PMN-PT heterostructure ▶     Ying-Ying Zhao, Jing Wang, Hao Kuang et al.     Memory effect of electric-field control on magnetic behavior in magnetoelectric composite heterostructures has been a topic of interest for a long time. Although the piezostrain …             Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging ▶     Yanyan Fan, Helin Liu, Rongcheng Han et al.     Materials possessing high two photon absorption (TPA) are highly desirable for a range of fields, such as three-dimensional data storage, TP microscopy (TPM) and photodynamic …             Unusual ferromagnetism enhancement in ferromagnetically optimal manganite La0.7−yCa0.3+yMn1−yRuyO3 (0≤y<0.3): the role of Mn-Ru t2g super-exchange ▶     M. F. Liu, Z. Z. Du, Y. L. Xie et al.     The eg-orbital double-exchange mechanism as the core of physics of colossal magnetoresistance (CMR) manganites is well known, which usually covers up the role of super-exchange at …             Magic electron affection in preparation process of silicon nanocrystal ▶     Wei-Qi Huang, Shi-Rong Liu, Zhong-Mei Huang et al.     It is very interesting that magic electron affection promotes growth of nanocrystals due to nanoscale characteristics of electronic de Broglie wave which produces resonance to …             Droplet-interface-bilayer assays in microfluidic passive networks ▶     Bárbara Schlicht, Michele Zagnoni     Basic biophysical studies and pharmacological processes can be investigated by mimicking the intracellular and extracellular environments across an artificial cell membrane …             100-nm-sized magnetic domain reversal by the magneto-electric effect in self-assembled BiFeO3/CoFe2O4 bilayer films ▶     Keita Sone, Hiroshi Naganuma, Masaki Ito et al.     A (001)-epitaxial-BiFeO3/CoFe2O4 bilayer was grown by self-assembly on SrTiO3 (100) substrates by just coating a mixture precursor solution. The thickness ratio of the bilayer …             Development of a 3D printer using scanning projection stereolithography ▶     Michael P. Lee, Geoffrey J. T. Cooper, Trevor Hinkley et al.     We have developed a system for the rapid fabrication of low cost 3D devices and systems in the laboratory with micro-scale features yet cm-scale objects. Our system is inspired by …             Loss of superhydrophobicity of hydrophobic micro/nano structures during condensation ▶     HangJin Jo, Kyung Won Hwang, DongHyun Kim et al.     Condensed liquid behavior on hydrophobic micro/nano-structured surfaces is a subject with multiple practical applications, but remains poorly understood. In particular, the loss …             Work-Hardening Induced Tensile Ductility of Bulk Metallic Glasses via High-Pressure Torsion ▶     Soo-Hyun Joo, Dong-Hai Pi, Albertus Deny Heri Setyawan et al.     The mechanical properties of engineering materials are key for ensuring safety and reliability. However, the plastic deformation of BMGs is confined to narrow regions in shear …             When are Surface Plasmon Polaritons Excited in the Kretschmann-Raether Configuration? ▶     Jonathan J. Foley IV, Hayk Harutyunyan, Daniel Rosenmann et al.     It is widely believed that the reflection minimum in a Kretschmann-Raether experiment results from direct coupling into surface plasmon polariton modes. Our experimental results …             Temperature Dependence of Electric Transport in Few-layer Graphene under Large Charge Doping Induced by Electrochemical Gating ▶     R. S. Gonnelli, F. Paolucci, E. Piatti et al.     The temperature dependence of electric transport properties of single-layer and few-layer graphene at large charge doping is of great interest both for the study of the scattering …             A multi-functional bubble-based microfluidic system ▶     Khashayar Khoshmanesh, Abdullah Almansouri, Hamad Albloushi et al.     Recently, the bubble-based systems have offered a new paradigm in microfluidics. Gas bubbles are highly flexible, controllable and barely mix with liquids, and thus can be used …             Antibacterial activity of silver-killed bacteria: the "zombies" effect ▶     Racheli Ben-Knaz Wakshlak, Rami Pedahzur, David Avnir     We report a previously unrecognized mechanism for the prolonged action of biocidal agents, which we denote as the zombies effect: biocidally-killed bacteria are capable of killing …             Enhancing participation to health screening campaigns by group interactions ▶     Raffaella Burioni, Pierluigi Contucci, Micaela Fedele et al.     Improving the prevention efficacy of health screening campaigns by increasing their attendance rate represents a challenge that calls for new strategies. This paper analyzes the …             Solitons shedding from Airy beams and bound states of breathing Airy solitons in nonlocal nonlinear media ▶     Ming Shen, Jinsong Gao, Lijuan Ge     We investigate the spatially optical solitons shedding from Airy beams and anomalous interactions of Airy beams in nonlocal nonlinear media by means of direct numerical …             Optimal percentage of inhibitory synapses in multi-task learning ▶     Vittorio Capano, Hans J. Herrmann, Lucilla de Arcangelis     Performing more tasks in parallel is a typical feature of complex brains. These are characterized by the coexistence of excitatory and inhibitory synapses, whose percentage in …             The effect of ionic strength on oil adhesion in sandstone – the search for the low salinity mechanism ▶     E. Hilner, M. P. Andersson, T. Hassenkam et al.     Core flood and field tests have demonstrated that decreasing injection water salinity increases oil recovery from sandstone reservoirs. However, the microscopic mechanism behind …             Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation ▶     Yejing Weng, Zhigang Sui, Hao Jiang et al.     Due to the important roles of N-glycoproteins in various biological processes, the global N-glycoproteome analysis has been paid much attention. However, by current strategies for …             A Pure Inorganic ZnO-Co3O4 Overlapped Membrane for Efficient Oil/Water Emulsions Separation ▶     Na Liu, Xin Lin, Weifeng Zhang et al.     The earth's environmental problems, especially for water remediation, need effective methods to solve. Materials with special wettability are developed for the separation of …             Functional Optical Coherence Tomography Enables In Vivo Physiological Assessment of Retinal Rod and Cone Photoreceptors ▶     Qiuxiang Zhang, Rongwen Lu, Benquan Wang et al.     Transient intrinsic optical signal (IOS) changes have been observed in retinal photoreceptors, suggesting a unique biomarker for eye disease detection. However, clinical …             Aerosol-spray diverse mesoporous metal oxides from metal nitrates ▶     Long Kuai, Junxin Wang, Tian Ming et al.     Transition metal oxides are widely used in solar cells, batteries, transistors, memories, transparent conductive electrodes, photocatalysts, gas sensors, supercapacitors, and …             Ballistic bipolar junctions in chemically gated graphene ribbons ▶     Jens Baringhaus, Alexander Stöhr, Stiven Forti et al.     The realization of ballistic graphene pn-junctions is an essential task in order to study Klein tunneling phenomena. Here we show that intercalation of Ge under the buffer layer …             Cell voltage versus electrode potential range in aqueous supercapacitors ▶     Zengxin Dai, Chuang Peng, Jung Hoon Chae et al.     Supercapacitors with aqueous electrolytes and nanostructured composite electrodes are attractive because of their high charging-discharging speed, long cycle life, low …             Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat ▶     Hemmings Wu, Hartwin Ghekiere, Dorien Beeckmans et al.     Conventional deep brain stimulation (DBS) applies constant electrical stimulation to specific brain regions to treat neurological disorders. Closed-loop DBS with real-time …             Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18 ▶     Kerstin Sander, Thibault Gendron, Elena Yiannaki et al.     Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers …             Effects of substrate conductivity on cell morphogenesis and proliferation using tailored, atomic layer deposition-grown ZnO thin films ▶     Won Jin Choi, Jongjin Jung, Sujin Lee et al.     We demonstrate that ZnO films grown by atomic layer deposition (ALD) can be employed as a substrate to explore the effects of electrical conductivity on cell adhesion, …               Earth & Environmental Sciences ▲ top               Magnetic fabric from Red clay sediments in the Chinese Loess Plateau ▶     Hujun Gong, Rui Zhang, Leping Yue et al.     Well-distributed eolian red clay in a wide area of northern China is believed to imply the onset of an ancient East Asian monsoon system since Late Miocene. Two continuous red …             Magic electron affection in preparation process of silicon nanocrystal ▶     Wei-Qi Huang, Shi-Rong Liu, Zhong-Mei Huang et al.     It is very interesting that magic electron affection promotes growth of nanocrystals due to nanoscale characteristics of electronic de Broglie wave which produces resonance to …             An Ordovician variation on Burgess Shale-type biotas ▶     Joseph P. Botting, Lucy A. Muir, Naomi Jordan et al.     The Cambrian Burgess Shale-type biotas form a globally consistent ecosystem, usually dominated by arthropods. Elements of these communities continued into the Early Ordovician at …             A modelling methodology to assess the effect of insect pest control on agro-ecosystems ▶     Nian-Feng Wan, Xiang-Yun Ji, Jie-Xian Jiang et al.     The extensive use of chemical pesticides for pest management in agricultural systems can entail risks to the complex ecosystems consisting of economic, ecological and social …             Landslide susceptibility mapping using GIS-based statistical models and Remote sensing data in tropical environment ▶     Himan Shahabi, Mazlan Hashim     This research presents the results of the GIS-based statistical models for generation of landslide susceptibility mapping using geographic information system (GIS) and …             A Pure Inorganic ZnO-Co3O4 Overlapped Membrane for Efficient Oil/Water Emulsions Separation ▶     Na Liu, Xin Lin, Weifeng Zhang et al.     The earth's environmental problems, especially for water remediation, need effective methods to solve. Materials with special wettability are developed for the separation of …             Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing ▶     Ayumi Tanimura, Minako Kikukawa, Shino Yamaguchi et al.     Consolidated bioprocessing (CBP), which integrates enzyme production, saccharification and fermentation into a one-step process, is a promising strategy for cost-effective ethanol …             Comparing the model-simulated global warming signal to observations using empirical estimates of unforced noise ▶     Patrick T. Brown, Wenhong Li, Eugene C. Cordero et al.     The comparison of observed global mean surface air temperature (GMT) change to the mean change simulated by climate models has received much public and scientific attention. For a …               Health Sciences ▲ top               FOXO3 variants are beneficial for longevity in Southern Chinese living in the Red River Basin: A case-control study and meta-analysis ▶     Liang Sun, Caiyou Hu, Chenguang Zheng et al.     Forkhead box class O (FOXO) transcription factors play a crucial role in longevity across species. Several polymorphisms in FOXO3 were previously reported to be associated with …             Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative) ▶     M. Fernanda Lima-Costa, Laura C. Rodrigues, Maurício L. Barreto et al.     Brazil never had segregation laws defining membership of an ethnoracial group. Thus, the composition of the Brazilian population is mixed, and its ethnoracial classification is …             Cyclophilin A is Associated with Peripheral Artery Disease and Chronic Kidney Disease in Geriatrics: The Tianliao Old People (TOP) Study ▶     Meng-Chuan Liu, Yen-Wei Lee, Po-Tseng Lee et al.     Cyclophilin A (CyPA), secreted by vascular smooth muscle cells in response to oxidative stress, is important in the pathogenesis of progressive peripheral arterial occlusion …             Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence ▶     Putty-Reddy Sudhir, Shiu-Ting Lin, Chien Chia-Wen et al.     Identification and functional analysis of genes from genetically altered chromosomal regions would suggest new molecular targets for cancer diagnosis and treatment. Here we …             MicroRNA transcriptomes of distinct human NK cell populations identify miR-362-5p as an essential regulator of NK cell function ▶     Fang Ni, Chuang Guo, Rui Sun et al.     Natural killer (NK) cells are critical effectors in the immune response against malignancy and infection, and microRNAs (miRNAs) play important roles in NK cell biology. Here we …             A National Assessment of the Epidemiology of Severe Fever with Thrombocytopenia Syndrome, China ▶     Kun Liu, Hang Zhou, Ruo-Xi Sun et al.     First discovered in rural areas of middle-eastern China in 2009, severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis affecting hundreds of cases …             Oxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic system ▶     Xuexia Lin, Qiushui Chen, Wu Liu et al.     In this work, we report an integrated microfluidic device for cell co-culture under different concentrations of oxygen, in which the secreted protein VEGF165 was on-line …             Association of vitamin C, vitamin D, vitamin E and risk of bladder cancer: a dose-response meta-analysis ▶     Fuqiang Chen, Qingshu Li, Yang Yu et al.     A dose-response meta-analysis was conducted to assess the association of vitamin C, D, E with risk of bladder cancer. Pertinent studies were identified in PubMed and Embase. The …             Enhancing participation to health screening campaigns by group interactions ▶     Raffaella Burioni, Pierluigi Contucci, Micaela Fedele et al.     Improving the prevention efficacy of health screening campaigns by increasing their attendance rate represents a challenge that calls for new strategies. This paper analyzes the …             Prognostic value of pretreatment serum lactate dehydrogenase level in patients with solid tumors: a systematic review and meta-analysis ▶     Jiao Zhang, Yan-Hong Yao, Bao-Guo Li et al.     Although most studies have reported that high serum lactate dehydrogenase (LDH) levels are associated with poor prognosis in several malignancies, the consistency and magnitude of …             Strong influence of behavioral dynamics on the ability of testing and treating HIV to stop transmission ▶     Christopher J. Henry, James S. Koopman     Choosing between strategies to control HIV transmission with antivirals requires understanding both the dynamics affecting those strategies' effectiveness and what causes those …             Prognostic value of serum cytokeratin 19 fragments (Cyfra 21-1) in patients with non-small cell lung cancer ▶     Youtao Xu, Lei Xu, Mantang Qiu et al.     The role of serum CYFRA 21-1 level in patients with non-small cell lung cancer (NSCLC) remains to be defined. To re-evaluate the impact of serum CYFRA 21-1 in NSCLC survival, we …             The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells ▶     Basudev Chowdhury, Andrew McGovern, Yi Cui et al.     The USFDA approved “epigenetic drug”, Decitabine, exerts its effect by hypomethylating DNA, demonstrating the pivotal role aberrant genome-wide DNA methylation patterns play in …             Functional Optical Coherence Tomography Enables In Vivo Physiological Assessment of Retinal Rod and Cone Photoreceptors ▶     Qiuxiang Zhang, Rongwen Lu, Benquan Wang et al.     Transient intrinsic optical signal (IOS) changes have been observed in retinal photoreceptors, suggesting a unique biomarker for eye disease detection. However, clinical …             Intrinsic Functional Plasticity of the Sensory-Motor Network in Patients with Cervical Spondylotic Myelopathy ▶     F. Q. Zhou, Y. M. Tan, L. Wu et al.     Several neuroimaging studies have suggested brain reorganisation in patients with cervical spondylotic myelopathy (CSM); however, the changes in spontaneous neuronal activity that …             Recombinant Mutated Human TNF in Combination with Chemotherapy for Stage IIIB/IV Non-Small Cell Lung Cancer: A Randomized, Phase III Study ▶     Xiaowen Ma, Yang Song, Kuo Zhang et al.     Tumor necrosis factor (TNF), an anti-angiogenic agent in cancer treatment, is limited to isolated limb perfusion due to systemic toxicities. We previously prepared a TNF mutant …             Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18 ▶     Kerstin Sander, Thibault Gendron, Elena Yiannaki et al.     Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers …                 • Careers & Jobs           naturejobs.com Science jobs of the week       Research Fellow / Associate (Two Posts)     University of Bristol            PhD positions     Inserm Unit 1110            Postdoctoral Fellow     Indiana Univeristy School of Medicine            Tenure-Track Group Leader Positions     King's College London            Postdoctoral Fellow     University of Colorado            Tenure-Track Faculty Position     McMaster University            12 Tenure-Track Positions     NTNU - Trondheim Norwegian University of Science and Technology            Early Stage Researcher (ESR) / PhD     KU Leuven            Lecturer in Genetics / Genomics     The University of Manchester            Lab Manager Position     Princeton University          No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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