Nature Reviews Endocrinology - Table of Contents alert Volume 11 Issue 11

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TABLE OF CONTENTS
November 2015 Volume 11 Number 11
Impact Factor 13.281 *	In this issue Editorial Research Highlights News and Views Focus on: 10th anniversary issue Perspectives Reviews Also this month  Web focus: 10th anniversary issue
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EDITORIAL		Top
Celebrating 10 years of Nature Reviews Endocrinology Claire Greenhill Published online: 20 October 2015 p627 | doi:10.1038/nrendo.2015.170 Full Text | PDF
RESEARCH HIGHLIGHTS Top Diabetes: Important role for MPC complex in hepatic gluconeogenesis Published online: 22 September 2015 p629 | doi:10.1038/nrendo.2015.162 PDF Obesity: Gut microbiota, host genetics and diet interact to affect the risk of developing obesity and the metabolic syndrome Published online: 08 September 2015 p630 | doi:10.1038/nrendo.2015.152 PDF Exercise: 'Runner's high' abolished by leptin signalling in dopamine neurons in the ventral tegmental area Published online: 22 September 2015 p630 | doi:10.1038/nrendo.2015.161 PDF Thyroid: Laser ablation of thyroid nodules is rapid, safe and effective Published online: 08 September 2015 p631 | doi:10.1038/nrendo.2015.153 PDF Adrenal gland: Cancer target of mitotane identified Published online: 15 September 2015 p631 | doi:10.1038/nrendo.2015.156 PDF Bone: Antifracture efficacy of growth hormone—confirmation at long last Published online: 22 September 2015 p631 | doi:10.1038/nrendo.2015.160 PDF Cardiovascular endocrinology: High-intensity interval training benefits patients with T2DM Published online: 29 September 2015 p632 | doi:10.1038/nrendo.2015.171 PDF IN BRIEF Thyroid cancer: Positive results with lenvatinib for the treatment of advanced medullary thyroid cancer in a phase II trial | Metabolism: Dietary iron regulates appetite and metabolism via a leptin-dependent mechanism | Obesity: The causal role of obesity in diabetic kidney disease —evidence from a Mendelian randomization study PDF
NEWS AND VIEWS		Top
Decade in review—bone: Great strides made but still further to go Ian R. Reid Published online: 25 August 2015 p633 | doi:10.1038/nrendo.2015.143 Our understanding of bone biology and the subsequent development of therapies to treat bone diseases have both expanded greatly in the past 30 years. This article reviews some of the key advances made in these fields during the past decade. Full Text | PDF
Decade in review—thyroid disease: The endocrinology of thyroid disease from 2005 to 2015 P. Reed Larsen Published online: 06 October 2015 p634 | doi:10.1038/nrendo.2015.169 The past decade has seen exciting progress in the field of thyroid disease, especially in the evaluation of thyroid nodules, the genomic characterization of carcinomas and the treatment of carcinomas after surgery. An improved understanding of hyperthyroidism during pregnancy, as well as the causes of 'low T3 syndrome' and consumptive hypothyroidism have also been achieved. Full Text | PDF
Decade in review—type 2 diabetes mellitus: At the centre of things Guang Ning Published online: 25 August 2015 p636 | doi:10.1038/nrendo.2015.147 Over the past decade, the growing epidemic of type 2 diabetes mellitus (T2DM) and its associated complications has presented both challenges and opportunities. Progress has been made in incretin-based therapies, bariatric surgeries and inhibiting renal glucose reabsorption; however, long-term safety and efficacy studies are required. Advances in the prevention of macrovascular complications of T2DM from ongoing clinical trials are expected soon. Full Text | PDF
Decade in review—paediatric endocrinology: New genes, new therapies Mehul T. Dattani Published online: 08 September 2015 p638 | doi:10.1038/nrendo.2015.154 The past 10 years have seen substantial advances in many areas of paediatric endocrinology. Major progress has been made in our understanding of the aetiology of many disorders with the advent of next-generation sequencing. Furthermore, the introduction of novel therapies has revolutionized clinical management. Full Text | PDF
Decade in review—reproductive endocrinology: Understanding reproductive endocrine disorders Ursula B. Kaiser Published online: 13 October 2015 p640 | doi:10.1038/nrendo.2015.179 The past decade has witnessed incredible advances in the field of reproductive endocrinology. The use of new genetic and genomic tools has had a particular impact, leading to advances in our understanding, diagnosis and treatment of reproductive endocrine disorders, particularly those related to the neuroendocrine control of reproduction and ovarian biology. Full Text | PDF
Focus on: 10th anniversary issue PERSPECTIVES Top VIEWPOINT Endocrinology research—reflecting on the past decade and looking to the next Kevan C. Herold, Joseph A. Majzoub, Shlomo Melmed, Merri Pendergrass & Martin Schlumberger Published online: 13 October 2015 p672 | doi:10.1038/nrendo.2015.164 Here, five of our Advisory Board Members look back at the past decade of endocrinology research, highlighting key advances and identifying roadblocks. They also discuss where effort and money should be invested now and speculate on where progress might be made in the coming decade. Abstract | Full Text | PDF VIEWPOINT The past 10 years—new hormones, new functions, new endocrine organs Roger Bouillon, Daniel J. Drucker, Ele Ferrannini, Steven Grinspoon, Clifford J. Rosen & Paul Zimmet Published online: 01 September 2015 p681 | doi:10.1038/nrendo.2015.142 In this Viewpoint, six members of our Advisory Board comment on advances in the past 10 years that have revealed new hormones, new functions for known hormones and endocrine organs and new endocrine roles for well-known organs. The authors discuss how bone was recognized as an endocrine organ, the emerging understanding of the importance of gut hormones, targeting ectopic adipose tissue and the pathogenesis and treatment of type 2 diabetes mellitus. Abstract | Full Text | PDF
REVIEWS		Top
Scope and limitations of iodothyronine deiodinases in hypothyroidism Balázs Gereben, Elizabeth A. McAninch, Miriam O. Ribeiro & Antonio C. Bianco Published online: 29 September 2015 p642 | doi:10.1038/nrendo.2015.155 This Review outlines the physiologic role of the iodothyronine deiodinases, as well as the changes that occur in hypothyroidism, with a particular focus on their role in preserving thyroid hormone levels in the brain. Novel findings that underscore the clinical importance of iodothyronine deiodinases in hypothyroidism are also discussed. Abstract | Full Text | PDF
Endocrine disruptors and obesity Jerrold J. Heindel, Retha Newbold & Thaddeus T. Schug Published online: 22 September 2015 p653 | doi:10.1038/nrendo.2015.163 A subclass of endocrine-disrupting chemicals, so-called 'obesogens', have been proposed to predispose certain individuals to weight gain, despite their efforts to limit caloric intake and increase levels of physical activity. In this Review, Jerrold Heindel and colleagues discuss the experimental and epidemiological findings on obesogens, their modes of action, and their role in the obesity epidemic. Abstract | Full Text | PDF
Paget's disease of bone—genetic and environmental factors Frederick R. Singer Published online: 18 August 2015 p662 | doi:10.1038/nrendo.2015.138 Paget's disease is a disorder of bone that manifests in one or several bones and is initiated by osteoclast-induced osteolytic lesions. In addition to a genetic cause, environmental factors, including measles virus, have been proposed to have a role in the pathogenesis of Paget's disease. Here, Frederick R. Singer discusses the present knowledge and controversies surrounding the aetiology of Paget's disease. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2015. Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

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