Nature Reviews Cardiology - Table of Contents alert Volume 12 Issue 12

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TABLE OF CONTENTS
December 2015 Volume 12 Number 12
Impact Factor 9.183 *	In this issue Research Highlights News and Views Reviews Correspondence Erratum Also this month  Featured article: Mitral valve disease—morphology and mechanisms Robert A. Levine, Albert A. Hagége, Daniel P. Judge et al. for the Leducq Mitral Transatlantic Network
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RESEARCH HIGHLIGHTS Top Hypertension: PATHWAY to improving the treatment of drug-resistant hypertension Published online: 06 October 2015 p681 | doi:10.1038/nrcardio.2015.158 PDF Risk factors: Alcohol intake, MI, and income level Published online: 06 October 2015 p682 | doi:10.1038/nrcardio.2015.159 PDF Anticoagulation therapy: Sulodexide reduces the risk of recurrent venous thromboembolism Published online: 13 October 2015 p682 | doi:10.1038/nrcardio.2015.163 PDF Dyslipidaemia: Promising new therapy for lysosomal acid lipase deficiency Published online: 29 September 2015 p683 | doi:10.1038/nrcardio.2015.154 PDF Valvular disease: Importance of balloon valvuloplasty before TAVI to prevent embolization Published online: 06 October 2015 p683 | doi:10.1038/nrcardio.2015.160 PDF Thrombosis: Leaflet motion after TAVI or SAVR Published online: 27 October 2015 p683 | doi:10.1038/nrcardio.2015.170 PDF Cardiomyopathies: Clinical features of patients with Takotsubo syndrome Published online: 22 September 2015 p684 | doi:10.1038/nrcardio.2015.153 PDF Cardioprotection: Remote ischaemic preconditioning—no effect on clinical outcomes after CABG surgery Published online: 27 October 2015 p684 | doi:10.1038/nrcardio.2015.171 PDF Cardiology JOBS of the week Technician and Lab Manager University of Illinois More Science jobs from Cardiology EVENT The Heart Beat of Cardiology: Practical Application of Echocardiography 10.12.15 Chicago, USA More science events from
NEWS AND VIEWS		Top
Heart failure: Central sleep apnoea in HF—what can we learn from SERVE-HF? Olaf Oldenburg & Dieter Horstkotte Published online: 03 November 2015 p686 | doi:10.1038/nrcardio.2015.168 The results of the first randomized, controlled trial to assess adaptive servo-ventilation (ASV) for central sleep apnoea were expected to confirm the positive findings from previous observational studies and meta-analyses. However, ASV did not have the expected beneficial effects for patients with heart failure and reduced ejection fraction. Full Text | PDF
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REVIEWS		Top
Mitral valve disease—morphology and mechanisms Robert A. Levine, Albert A. Hagége, Daniel P. Judge, Muralidhar Padala, Jacob P. Dal-Bianco, Elena Aikawa, Jonathan Beaudoin, Joyce Bischoff, Nabila Bouatia-Naji, Patrick Bruneval, Jonathan T. Butcher, Alain Carpentier, Miguel Chaput, Adrian H. Chester, Catherine Clusel, Francesca N. Delling, Harry C. Dietz, Christian Dina, Ronen Durst, Leticia Fernandez-Friera, Mark D. Handschumacher, Morten O. Jensen, Xavier P. Jeunemaitre, Hervé Le Marec, Thierry Le Tourneau, Roger R. Markwald, Jean Mérot, Emmanuel Messas, David P. Milan, Tui Neri, Russell A. Norris, David Peal, Maelle Perrocheau, Vincent Probst, Michael Pucéat, Nadia Rosenthal, Jorge Solis, Jean-Jacques Schott, Ehud Schwammenthal, Susan A. Slaugenhaupt, Jae-Kwan Song, Magdi H. Yacoub & for the Leducq Mitral Transatlantic Network Published online: 20 October 2015 p689 | doi:10.1038/nrcardio.2015.161 Mitral valve disease is a common cause of heart failure and death. In this Review from members of the Leducq Transatlantic Network, Levine and colleagues extensively summarize the molecular and cellular mechanisms underlying the dynamic changes that occur during progression of mitral valve disease, and indicate how improved understanding of the pathophysiology might lead to the discovery of novel therapeutic options. Abstract | Full Text | PDF
MicroRNAs in platelet function and cardiovascular disease David D. McManus & Jane E. Freedman Published online: 07 July 2015 p711 | doi:10.1038/nrcardio.2015.101 Despite being anucleate, platelets contain RNA transcripts, including microRNAs, which are involved in regulating platelet function and which can also be transferred to other vascular cells. In this Review, McManus and Freedman summarize the mechanistic roles of platelet-derived miRNAs in acute atherogenic and thrombotic diseases, such as acute coronary syndromes and stroke. These miRNAs might also be used as biomarkers of cardiovascular disease susceptibility, prognosis, and treatment. Abstract | Full Text | PDF
Use of medication for cardiovascular disease during pregnancy Petronella G. Pieper Published online: 20 November 2015 p718 | doi:10.1038/nrcardio.2015.172 The numerous physiological changes that occur during pregnancy can affect the pharmacokinetics of drugs that a woman is receiving, often warranting an alteration in dosage. The well-being of the fetus is a major concern among pregnant women who require treatment for their heart disease. In this Review, Pieper provides an overview of the pharmacokinetic changes in drugs for cardiovascular disease during pregnancy, and how these might affect the fetus. Abstract | Full Text | PDF
New medical therapies for heart failure Thomas G. von Lueder & Henry Krum Published online: 29 September 2015 p730 | doi:10.1038/nrcardio.2015.137 Heart failure is a major global health problem with unmet therapeutic requirements despite the development of neurohormonal modulators for systolic heart failure. In this Review, the authors discuss the evidence resulting from clinical trials of novel pharmacological agents targeting contractility, neurohormonal signalling, vasodilatation, renal preservation, inflammation, and myocardial protection. Abstract | Full Text | PDF
CORRESPONDENCE		Top
Cardiovascular mortality trends in Russia: possible mechanisms Sergei V. Jargin Published online: 27 October 2015 p740 | doi:10.1038/nrcardio.2015.166 Full Text | PDF
REPLY		Top
High cardiovascular mortality in Russia: role of alcohol versus smoking, blood pressure, and treatment David A. Leon & Majid Ezzati Published online: 27 October 2015 p740 | doi:10.1038/nrcardio.2015.167 Full Text | PDF
ERRATUM
Erratum: Constrictive pericarditis—a curable diastolic heart failure Faisal F. Syed, Hartzell V. Schaff & Jae K. Oh Published online: 06 October 2015 p682 | doi:10.1038/nrcardio.2015.162 Full Text | PDF
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*Journal Citation Reports, Thomson, 2015. Nature Reviews Cardiology was previously published as Nature Clinical Practice Cardiovascular Medicine.

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