Nature Reviews Endocrinology - Table of Contents alert Volume 12 Issue 8

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TABLE OF CONTENTS
August 2016 Volume 12 Number 8
Impact Factor 15.432 *	In this issue Research Highlights News and Views Reviews Also this month  Featured article: The role of diet and exercise in the transgenerational epigenetic landscape of T2DM Romain Barrès & Juleen R. Zierath
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RESEARCH HIGHLIGHTS Top Adrenal gland: The genetics of adrenocortical carcinoma revealed Published online: 03 June 2016 p433 | doi:10.1038/nrendo.2016.89 PDF Exercise: Osteocalcin in the adaptation to exercise Published online: 24 June 2016 p434 | doi:10.1038/nrendo.2016.102 PDF Thyroid function: Poor thyroid function linked to NAFLD Published online: 24 June 2016 p434 | doi:10.1038/nrendo.2016.103 PDF In the news: ECE2016 — like-minds meet in Munich Published online: 10 June 2016 p435 | doi:10.1038/nrendo.2016.92 PDF Adipose tissue: BAT affects lipid metabolism Published online: 17 June 2016 p435 | doi:10.1038/nrendo.2016.97 PDF Bone diseases: Dual sclerostin-DKK1 antibody outperforms monotherapy Published online: 17 June 2016 p435 | doi:10.1038/nrendo.2016.99 PDF Metabolism: Acetate promotes obesity via a gut-brain-β-cell axis Published online: 10 June 2016 p436 | doi:10.1038/nrendo.2016.93 PDF IN BRIEF Adipose tissue: Adipocyte exosomes drive melanoma progression | Reproductive endocrinology: Acquisition of kisspeptin responsiveness is key to reversal of hypogonadotropic hypogonadism | Neuroendocrinology: Exome sequencing aids targeted treatment of inborn errors of metabolism PDF Endocrinology EVENT 17th International Congress of Endocrinology in collaboration with the 15th Annual Meeting of the Chinese Society of Endocrinology 31.08.16 Tel Aviv, Israel More science events from
NEWS AND VIEWS		Top
Disease watch: Zika virus — placental passage and permissivity for infection Melissa A. Suter & Kjersti M. Aagaard Published online: 24 June 2016 p437 | doi:10.1038/nrendo.2016.101 Animal models of human congenital infection are needed to understand when, how and why Zika virus (ZIKV) is transmitted to the fetus. The recent development of mouse models of ZIKV placental transmission, which results in high rates of pregnancy loss, alongside fetal brain and ocular malformations, have started to unravel the mysteries of placental infection and transmission. Full Text | PDF
Reproductive endocrinology: Contraceptives, exercise and diet — are all three needed in PCOS? Bulent O. Yildiz Published online: 12 July 2016 p438 | doi:10.1038/nrendo.2016.106 Oral contraceptives are the mainstay of long-term PCOS treatment, but have potential adverse cardiometabolic effects. In a randomized controlled trial comparing oral contraceptive use and structured exercise in women with PCOS and overweight on a calorie-restricted diet, androgen excess was ameliorated with oral contraceptive use and structured exercise improved markers of cardiometabolic risk. Full Text | PDF
REVIEWS		Top
The role of diet and exercise in the transgenerational epigenetic landscape of T2DM Romain Barrès & Juleen R. Zierath Published online: 17 June 2016 p441 | doi:10.1038/nrendo.2016.87 In this Review, Romain Barrès and Juleen Zierath outline the current understanding of the mechanisms underlying how lifestyle factors affect epigenetic changes involved in the risk of type 2 diabetes mellitus. The latest findings on the mechanisms by which diet and exercise affect the epigenome are also discussed. Abstract | Full Text | PDF
Control of puberty onset and fertility by gonadotropin-releasing hormone neurons Allan E. Herbison Published online: 20 May 2016 p452 | doi:10.1038/nrendo.2016.70 An elaborate neural network integrating many internal homeostatic and external signals governs the onset of puberty and subsequent fertility. Here, Allan Herbison provides an update on the morphology and function of the gonadotropin-releasing hormone neurons, focusing on their role in the onset of puberty and fertility. Abstract | Full Text | PDF
Progress in the care of common inherited atherogenic disorders of apolipoprotein B metabolism Katrina L. Ellis, Amanda J. Hooper, John R. Burnett & Gerald F. Watts Published online: 20 May 2016 p467 | doi:10.1038/nrendo.2016.69 In this Review, screening and treatment recommendations are compared for familial hypercholesterolaemia, familial combined hyperlipidaemia and elevated lipoprotein(a); common, inherited disorders of lipoprotein metabolism that are associated with atherosclerotic cardiovascular disease. New treatments are considered alongside established therapeutic strategies. Abstract | Full Text | PDF | Supplementary information
NADPH oxidases: new actors in thyroid cancer? Rabii Ameziane-El-Hassani, Martin Schlumberger & Corinne Dupuy Published online: 13 May 2016 p485 | doi:10.1038/nrendo.2016.64 The NADPH oxidase family of enzymes produce hydrogen peroxide (H2O2), a critical substrate for thyroid hormone synthesis. However, H2O2 is also a potent oxidant that can cause DNA damage, which might lead to thyroid carcinogenesis. Here, the authors discuss the physiological attributes of thyroid NADPH oxidases and their pathological involvement in thyroid cancer. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2015. Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

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