Molecular Therapy - Table of Contents alert Volume 24 Issue 9

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TABLE OF CONTENTS Volume 24, Issue 9 (September 2016) In this issue Editorial In This Issue Research Highlights Letter to the Editor Commentary Review Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe   Advertisement In January 2017 Cell Press will take over publishing the Molecular Therapy family of journals. To keep receiving e-alerts for these titles, please visit http://www.cell.com/molecular-therapy-family/home     Editorial Top A Cure For Hemophilia: the Promise Becomes a Reality Roland W Herzog Mol Ther 2016 24: 1503-1504; 10.1038/mt.2016.169 Full Text In This Issue Top In This Issue Mol Ther 2016 24: 1506; 10.1038/mt.2016.170 Full Text Research Highlights Top Research Highlights Mol Ther 2016 24: 1507; 10.1038/mt.2016.171 Full Text Letter to the Editor Top A Self-restricted CRISPR System to Reduce Off-target Effects Yanhao Chen, Xiaojian Liu, Yongxian Zhang, Hui Wang, Hao Ying, Mingyao Liu, Dali Li, Kathy O Lui and Qiurong Ding Mol Ther 2016 24: 1508-1510; 10.1038/mt.2016.172 Full Text Commentary Top Man’s Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers Melinda Mata and Stephen Gottschalk Mol Ther 2016 24: 1511-1512; 10.1038/mt.2016.173 Full Text Review Top Viral and Synthetic RNA Vector Technologies and Applications Juliane W Schott, Michael Morgan, Melanie Galla and Axel Schambach Mol Ther 2016 24: 1513-1527; advance online publication, July 5, 2016; 10.1038/mt.2016.143 Abstract | Full Text Original Articles Top Development of an Attenuated Tat Protein as a Highly-effective Agent to Specifically Activate HIV-1 LatencyMTOPEN Guannan Geng, Bingfeng Liu, Cancan Chen, Kang Wu, Jun Liu, Yijun Zhang, Ting Pan, Jun Li, Yue Yin, Junsong Zhang, Feng Huang, Fei Yu, Jingliang Chen, Xiancai Ma, Jie Zhou, Ersheng Kuang, Chao Liu, Weiping Cai and Hui Zhang Mol Ther 2016 24: 1528-1537; advance online publication, June 6, 2016; 10.1038/mt.2016.117 Abstract | Full Text In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral IschemiaMTOPEN Jung Hwa Seo, Min-Young Lee, Ji Hea Yu, Myung-Sun Kim, Myungjae Song, Cheong Hoon Seo, Hyongbum (Henry) Kim and Sung-Rae Cho Mol Ther 2016 24: 1538-1549; advance online publication, June 22, 2016; 10.1038/mt.2016.124 Abstract | Full Text Anti-apoptotic Effects of Human Wharton’s Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1 SooJin Kwon, Soo Mi Ki, Sang Eon Park, Min-Jeong Kim, Brian Hyung, Na Kyung Lee, Sangmi Shim, Byung-Ok Choi, Duk L Na, Ji Eun Lee and Jong Wook Chang Mol Ther 2016 24: 1550-1560; advance online publication, June 23, 2016; 10.1038/mt.2016.125 Abstract | Full Text CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells Megan D Hoban, Dianne Lumaquin, Caroline Y Kuo, Zulema Romero, Joseph Long, Michelle Ho, Courtney S Young, Michelle Mojadidi, Sorel Fitz-Gibbon, Aaron R Cooper, Georgia R Lill, Fabrizia Urbinati, Beatriz Campo-Fernandez, Carmen F Bjurstrom, Matteo Pellegrini, Roger P Hollis and Donald B Kohn Mol Ther 2016 24: 1561-1569; advance online publication, July 1, 2016; 10.1038/mt.2016.148 Abstract | Full Text High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k “Helper” Proteins Kamila S Gwiazda, Alexandra E Grier, Jaya Sahni, Stephen M Burleigh, Unja Martin, Julia G Yang, Nicholas A Popp, Michelle C Krutein, Iram F Khan, Kyle Jacoby, Michael C Jensen, David J Rawlings and Andrew M Scharenberg Mol Ther 2016 24: 1570-1580; advance online publication, May 16, 2016; 10.1038/mt.2016.105 Abstract | Full Text Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression Xiaoou Jiang, Han Yu, Cui Rong Teo, Genim Siu Xian Tan, Sok Chin Goh, Parasvi Patel, Yiqiang Kevin Chua, Nasirah Banu Sahul Hameed, Antonio Bertoletti and Volker Patzel Mol Ther 2016 24: 1581-1591; advance online publication, June 30, 2016; 10.1038/mt.2016.138 Abstract | Full Text Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy Erkan Y Osman, Charles W Washington, III, Kevin A Kaifer, Chiara Mazzasette, Teresa N Patitucci, Kyra M Florea, Madeline E Simon, Chien-Ping Ko, Allison D Ebert and Christian L Lorson Mol Ther 2016 24: 1592-1601; advance online publication, July 1, 2016; 10.1038/mt.2016.145 Abstract | Full Text Feasibility and Safety of RNA-transfected CD20-specific Chimeric Antigen Receptor T Cells in Dogs with Spontaneous B Cell Lymphoma M Kazim Panjwani, Jenessa B Smith, Keith Schutsky, Josephine Gnanandarajah, Colleen M O’Connor, Daniel J Powell, Jr and Nicola J Mason Mol Ther 2016 24: 1602-1614; advance online publication, July 12, 2016; 10.1038/mt.2016.146 Abstract | Full Text CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia Challice L Bonifant, Arpad Szoor, David Torres, Nicholos Joseph, Mireya Paulina Velasquez, Kota Iwahori, Amos Gaikwad, Phuong Nguyen, Caroline Arber, Xiao-Tong Song, Michele Redell and Stephen Gottschalk Mol Ther 2016 24: 1615-1626; advance online publication, June 6, 2016; 10.1038/mt.2016.116 Abstract | Full Text Polymeric Cups for Cavitation-mediated Delivery of Oncolytic Vaccinia VirusMTOPEN Rachel Myers, Christian Coviello, Philippe Erbs, Johann Foloppe, Cliff Rowe, James Kwan, Calum Crake, Seán Finn, Edward Jackson, Jean-Marc Balloul, Colin Story, Constantin Coussios and Robert Carlisle Mol Ther 2016 24: 1627-1633; advance online publication, July 4, 2016; 10.1038/mt.2016.139 Abstract | Full Text Reduction of Minimal Residual Disease in Pediatric B-lineage Acute Lymphoblastic Leukemia by an Fc-optimized CD19 Antibody Ursula Jördis Eva Seidel, Patrick Schlegel, Ludger Grosse-Hovest, Martin Hofmann, Steffen Aulwurm, Elwira Pyz, Friedhelm R Schuster, Roland Meisel, Martin Ebinger, Tobias Feuchtinger, Heiko-Manuel Teltschik, Kai-Erik Witte, Carl-Philipp Schwarze, Hans-Georg Rammensee, Rupert Handgretinger, Gundram Jung and Peter Lang Mol Ther 2016 24: 1634-1643; advance online publication, July 6, 2016; 10.1038/mt.2016.141 Abstract | Full Text Inducible HGF-secreting Human Umbilical Cord Blood-derived MSCs Produced via TALEN-mediated Genome Editing Promoted AngiogenesisMTOPEN Hyun-Kyung Chang, Pyung-Hwan Kim, Hyun-Min Cho, Soo-Young Yum, Young-Jin Choi, YeonSung Son, DaBin Lee, InSung Kang, Kyung-Sun Kang, Goo Jang and Je-Yoel Cho Mol Ther 2016 24: 1644-1654; advance online publication, June 10, 2016; 10.1038/mt.2016.120 Abstract | Full Text Adenosine Selectively Depletes Alloreactive T Cells to Prevent GVHD While Conserving Immunity to Viruses and Leukemia Greg D Whitehill, Shoba Amarnath, Pawel Muranski, Keyvan Keyvanfar, Minoo Battiwalla, Austin J. Barrett and Dhanalakshmi Chinnassamy Mol Ther 2016 24: 1655-1664; advance online publication, July 1, 2016; 10.1038/mt.2016.147 Abstract | Full Text Local Inhibition of Complement Improves Mesenchymal Stem Cell Viability and Function After Administration Yan Li, John Fung and Feng Lin Mol Ther 2016 24: 1665-1674; advance online publication, July 5, 2016; 10.1038/mt.2016.142 Abstract | Full Text Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants Elodie Belnoue, Wilma Di Berardino-Besson, Hubert Gaertner, Susanna Carboni, Isabelle Dunand-Sauthier, Fabrice Cerini, Else-Marit Suso-Inderberg, Sébastien Wälchli, Stéphane König, Andres M Salazar, Oliver Hartley, Pierre-Yves Dietrich, Paul R Walker and Madiha Derouazi Mol Ther 2016 24: 1675-1685; advance online publication, July 5, 2016; 10.1038/mt.2016.134 Abstract | Full Text Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines Laure Lambricht, Kevin Vanvarenberg, Ans De Beuckelaer, Lien Van Hoecke, Johan Grooten, Bernard Ucakar, Pascale Lipnik, Niek N Sanders, Stefan Lienenklaus, Véronique Préat and Gaëlle Vandermeulen Mol Ther 2016 24: 1686-1696; advance online publication, June 20, 2016; 10.1038/mt.2016.122 Abstract | Full Text Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study Kathleen F Pirollo, John Nemunaitis, Po Ki Leung, Robert Nunan, Jana Adams and Esther H Chang Mol Ther 2016 24: 1697-1706; advance online publication, June 30, 2016; 10.1038/mt.2016.135 Abstract | Full Text Advertisement Molecular Therapy - Methods & Clinical Development: now indexed in PubMed and PubMed Central An online-only, open access journal publishing top-quality, novel methods and technology development, as well as significant improvements to established research techniques in basic, translational, and clinical cell and gene therapy. 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