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2014/05/27

Scientific Reports Table of Contents e-alert: 27 May 2014

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Biological Sciences top
 
 
 
 
 
 
 

What triggers the rising of an intraspecific biodiversity hotspot? Hints from the agile frog

 
 

Daniele Canestrelli, Roberta Bisconti, Florinda Sacco et al.

 
 

Hotspots of genetic diversity are regions of utmost importance for species survival and conservation, and their intimate link with the geographic location of glacial refugia has …

 
 
 
 
 
 

Nanoliter-Scale Protein Crystallization and Screening with a Microfluidic Droplet Robot

 
 

Ying Zhu, Li-Na Zhu, Rui Guo et al.

 
 

Large-scale screening of hundreds or even thousands of crystallization conditions while with low sample consumption is in urgent need, in current structural biology research. Here …

 
 
 
 
 
 

Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity

 
 

Zhiyao Fu, Feven Berhane, Alemu Fite et al.

 
 

Lipasin (also known as C19ORF80, RIFL, ANGPTL8 and betatrophin) is a newly discovered circulating factor that regulates lipid metabolism and promotes pancreatic β-cell …

 
 
 
 
 
 

Regulation of secondary cell wall biosynthesis by poplar R2R3 MYB transcription factor PtrMYB152 in Arabidopsis

 
 

Shucai Wang, Eryang Li, Ilga Porth et al.

 
 

Poplar has 192 annotated R2R3 MYB genes, of which only three have been shown to play a role in the regulation of secondary cell wall formation. Here we report the characterization …

 
 
 
 
 
 

Involvement of the Wbp pathway in the biosynthesis of Porphyromonas gingivalis lipopolysaccharide with anionic polysaccharide

 
 

Mikio Shoji, Keiko Sato, Hideharu Yukitake et al.

 
 

The periodontal pathogen Porphyromonas gingivalis has two different lipopolysaccharide (LPS) molecules, O-LPS and A-LPS. We have recently shown that P. gingivalis strain HG66 …

 
 
 
 
 
 

Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus

 
 

Yohei Matsubara, Tomoki Chiba, Kenichi Kashimada et al.

 
 

X-linked severe combined immunodeficiency (SCID-X1) caused by mutations in interleukin 2 receptor gamma (IL2RG) gene threatens the survival of affected boys during the first year …

 
 
 
 
 
 

Effects of externally supplied protein on root morphology and biomass allocation in Arabidopsis

 
 

Thierry G. A. Lonhienne, Yuri Trusov, Anthony Young et al.

 
 

Growth, morphogenesis and function of roots are influenced by the concentration and form of nutrients present in soils, including low molecular mass inorganic N (IN, ammonium, …

 
 
 
 
 
 

PCR amplification of repetitive DNA: a limitation to genome editing technologies and many other applications

 
 

Carl Maximilian Hommelsheim, Lamprinos Frantzeskakis, Mengmeng Huang et al.

 
 

Designer transcription-activator like effectors (TALEs) is a promising technology and made it possible to edit genomes with higher specificity. Such specific engineering and gene …

 
 
 
 
 
 

PHF8 and REST/NRSF co-occupy gene promoters to regulate proximal gene expression

 
 

Juan Wang, Xueqiu Lin, Su Wang et al.

 
 

Chromatin regulators play an important role in the development of human diseases. In this study, we focused on Plant Homeo Domain Finger protein 8 (PHF8), a chromatin regulator …

 
 
 
 
 
 

Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis

 
 

Takako Iitsuka, Kaoru Mita, Akiko Hozumi et al.

 
 

Maternal mRNAs play crucial roles during early embryogenesis of ascidians, but their functions are largely unknown. In this study, we developed a new method to specifically …

 
 
 
 
 
 

Strong non-classical induction forces in ion-surface interactions: General origin of Hofmeister effects

 
 

Xinmin Liu, Hang Li, Rui Li et al.

 
 

Hofmeister effects continue to defy all-encompassing theories, and their origin is still a matter of debate. We observed strong Hofmeister effects in Ca2/Na exchange on a …

 
 
 
 
 
 

Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations

 
 

Graham K. Sheridan, Kumlesh K. Dev

 
 

Fingolimod (FTY720) is an oral therapy for relapsing remitting multiple sclerosis (MS) and targets sphingosine 1-phosphate receptors (S1PRs). FTY720 also rescues animals from …

 
 
 
 
 
 

Peripheral blood miRNAs as a biomarker for chronic cardiovascular diseases

 
 

Yong Jiang, Hui-yan Wang, Hong-mei Cao et al.

 
 

Vascular diseases are the most prevalent diseases worldwide. This study intended to analyze peripheral blood miRNA levels and their correlation with NT-pro-BNP and cTN-I in …

 
 
 
 
 
 

No evident dose-response relationship between cellular ROS level and its cytotoxicity – a paradoxical issue in ROS-based cancer therapy

 
 

Chunpeng Zhu, Wei Hu, Hao Wu et al.

 
 

Targeting cancer via ROS-based mechanism has been proposed as a radical therapeutic approach. Cancer cells exhibit higher endogenous oxidative stress than normal cells and …

 
 
 
 
 
 

Characterizing the effect of population heterogeneity on evolutionary dynamics on complex networks

 
 

Shaolin Tan, Jinhu Lü

 
 

Recently, the impact of network structure on evolutionary dynamics has been at the center of attention when studying the evolutionary process of structured populations. This paper …

 
 
 
 
 
 

Impaired Frontal-Basal Ganglia Connectivity in Adolescents with Internet Addiction

 
 

Baojuan Li, Karl J. Friston, Jian Liu et al.

 
 

Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study …

 
 
 
 
 
 

Fabricating nanopores with diameters of sub-1 nm to 3 nm using multilevel pulse-voltage injection

 
 

Itaru Yanagi, Rena Akahori, Toshiyuki Hatano et al.

 
 

To date, solid-state nanopores have been fabricated primarily through a focused-electronic beam via TEM. For mass production, however, a TEM beam is not suitable and an …

 
 
 
 
 
 

Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

 
 

Jichuang Wang, Zhou Jiang, Liping Xiang et al.

 
 

Ursolic acid (UA) is a naturally bioactive product that exhibits potential anticancer effects. The relatively safe and effective molecule intrigued us to explore a way to further …

 
 
 
 
 
 

Expression of Arabidopsis MYB transcription factor, AtMYB111, in tobacco requires light to modulate flavonol content

 
 

Ashutosh Pandey, Prashant Misra, Sweta Bhambhani et al.

 
 

Flavonoids, due to their pharmacological attributes, have recently become target molecules for metabolic engineering in commonly consumed food crops. Strategies including …

 
 
 
 
 
 

Promoting Interspecies Electron Transfer with Biochar

 
 

Shanshan Chen, Amelia-Elena Rotaru, Pravin Malla Shrestha et al.

 
 

Biochar, a charcoal-like product of the incomplete combustion of organic materials, is an increasingly popular soil amendment designed to improve soil fertility. We investigated …

 
 
 
 
 
 

Cholesterol level affects surface charge of lipid membranes in saline solution

 
 

Aniket Magarkar, Vivek Dhawan, Paraskevi Kallinteri et al.

 
 

Cholesterol is an important component of all biological membranes as well as drug delivery liposomes. We show here that increasing the level of cholesterol in a phospholipid …

 
 
 
 
 
 

Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization

 
 

Yan-Qing Guan, Zhe Zheng, Zheng Huang et al.

 
 

Nanomagnetic materials offer exciting avenues for advancing cancer therapies. Most researches have focused on efficient delivery of drugs in the body by incorporating various drug …

 
 
 
 
 
 

Mapping Brain Injury with Symmetrical-channels' EEG Signal Analysis – A Pilot Study

 
 

LI Yi, LIU Xiao-ping, LING Xian-hong et al.

 
 

A technique for detecting brain injury at the bedside has great clinical value, but conventional imaging techniques (such as computed tomography [CT] and magnetic resonance …

 
 
 
 
 
 

Revealing Real-Time Emotional Responses: a Personalized Assessment based on Heartbeat Dynamics

 
 

Gaetano Valenza, Luca Citi, Antonio Lanatá et al.

 
 

Emotion recognition through computational modeling and analysis of physiological signals has been widely investigated in the last decade. Most of the proposed emotion recognition …

 
 
 
 
 
 

PEG Molecular Net-Cloth Grafted on Polymeric Substrates and Its Bio-Merits

 
 

Changwen Zhao, Zhifeng Lin, Huabing Yin et al.

 
 

Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for the first time, we report a non-swelling …

 
 
 
 
 
 
 
 
Nature Reviews Immunology
Focus on Homeostatic immune responses
 
Read the Focus online:
 
 
 
 
Chemical Sciences top
 
 
 
 
 
 
 

Highly exposed {001} facets of titanium dioxide modified with reduced graphene oxide for dopamine sensing

 
 

Gregory Thien Soon How, Alagarsamy Pandikumar, Huang Nay Ming et al.

 
 

Titanium dioxide (TiO2) with highly exposed {001} facets was synthesized through a facile solvo-thermal method and its surface was decorated by using reduced graphene oxide (rGO) …

 
 
 
 
 
 

Transistor application of alkyl-substituted picene

 
 

Hideki Okamoto, Shino Hamao, Hidenori Goto et al.

 
 

Field-effect transistors (FETs) were fabricated with a thin film of 3,10-ditetradecylpicene, picene-(C14H29)2, formed using either a thermal deposition or a deposition from …

 
 
 
 
 
 

Insights into transport velocity of colloid-associated plutonium relative to tritium in porous media

 
 

Jinchuan Xie, Jiachun Lu, Jianfeng Lin et al.

 
 

Although faster transport velocities of colloid-associated actinides, bacteria, and virus than nonreactive solutes have been observed in laboratory and field experiments, some …

 
 
 
 
 
 

Role of the dispersion force in modeling the interfacial properties of molecule-metal interfaces: adsorption of thiophene on copper surfaces

 
 

Zhi-Xin Hu, Haiping Lan, Wei Ji

 
 

We present density functional theory calculations of the geometry, adsorption energy and electronic structure of thiophene adsorbed on Cu(111), Cu(110) and Cu(100) surfaces. Our …

 
 
 
 
 
 

PEG Molecular Net-Cloth Grafted on Polymeric Substrates and Its Bio-Merits

 
 

Changwen Zhao, Zhifeng Lin, Huabing Yin et al.

 
 

Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for the first time, we report a non-swelling …

 
 
 
 
 
 

Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings

 
 

Usawadee Sakulkhu, Morteza Mahmoudi, Lionel Maurizi et al.

 
 

Because of their biocompatibility and unique magnetic properties, superparamagnetic iron oxide nanoparticles NPs (SPIONs) are recognized as some of the most prominent agents for …

 
 
 
 
 
 
   
 
 
Physical Sciences top
 
 
 
 
 
 
 

Ultrahigh Performance C60 Nanorod Large Area Flexible Photoconductor Devices via Ultralow Organic and Inorganic Photodoping

 
 

Rinku Saran, Vlad Stolojan, Richard J. Curry

 
 

One dimensional single-crystal nanorods of C60 possess unique optoelectronic properties including high electron mobility, high photosensitivity and an excellent electron accepting …

 
 
 
 
 
 

Ultrafast spontaneous emission of copper-doped silicon enhanced by an optical nanocavity

 
 

HISASHI SUMIKURA, EIICHI KURAMOCHI, HIDEAKI TANIYAMA et al.

 
 

Dopants in silicon (Si) have attracted attention in the fields of photonics and quantum optics. However, the optical characteristics are limited by the small spontaneous emission …

 
 
 
 
 
 

A deformation mechanism of hard metal surrounded by soft metal during roll forming

 
 

Hailiang YU, A. Kiet TIEU, Cheng LU et al.

 
 

It is interesting to imagine what would happen when a mixture of soft-boiled eggs and stones is deformed together. A foil made of pure Ti is stronger than that made of Cu. When a …

 
 
 
 
 
 

Spectroscopic properties and energy transfer parameters of Er3+- doped fluorozirconate and oxyfluoroaluminate glasses

 
 

Feifei Huang, Xueqiang Liu, Lili Hu et al.

 
 

Er3- doped fluorozirconate (ZrF4-BaF2-YF3-AlF3) and oxyfluoroaluminate glasses are successfully prepared here. These glasses exhibit significant superiority compared with …

 
 
 
 
 
 

Wavelength-Versatile Graphene-Gold Film Saturable Absorber Mirror for Ultra-Broadband Mode-Locking of Bulk Lasers

 
 

Jie Ma, Guoqiang Xie, Peng Lv et al.

 
 

An ultra-broadband graphene-gold film saturable absorber mirror (GG-SAM) with a spectral coverage exceeding 1300 nm is experimentally demonstrated for mode-locking of bulk …

 
 
 
 
 
 

Highly exposed {001} facets of titanium dioxide modified with reduced graphene oxide for dopamine sensing

 
 

Gregory Thien Soon How, Alagarsamy Pandikumar, Huang Nay Ming et al.

 
 

Titanium dioxide (TiO2) with highly exposed {001} facets was synthesized through a facile solvo-thermal method and its surface was decorated by using reduced graphene oxide (rGO) …

 
 
 
 
 
 

Direct fabrication of graphene on SiO2 enabled by thin film stress engineering

 
 

Daniel Q. McNerny, B. Viswanath, Davor Copic et al.

 
 

We demonstrate direct production of graphene on SiO2 by CVD growth of graphene at the interface between a Ni film and the SiO2 substrate, followed by dry mechanical delamination …

 
 
 
 
 
 

Crystal-momentum dispersion of ultrafast spin change in fcc Co

 
 

M. S. Si, J. Y. Li, D. Z. Yang et al.

 
 

Nearly twenty years ago, Beaurepaire and coworkers showed that when an ultrafast laser impinges on a ferromagnet, its spin moment undergoes a dramatic change, but how it works …

 
 
 
 
 
 

Room temperature plasmonic lasing in a continuous wave operation mode from an InGaN/GaN single nanorod with a low threshold

 
 

Y. Hou, P. Renwick, B. Liu et al.

 
 

It is crucial to fabricate nano photonic devices such as nanolasers in order to meet the requirements for the integration of photonic and electronic circuits on the nanometre …

 
 
 
 
 
 

Transistor application of alkyl-substituted picene

 
 

Hideki Okamoto, Shino Hamao, Hidenori Goto et al.

 
 

Field-effect transistors (FETs) were fabricated with a thin film of 3,10-ditetradecylpicene, picene-(C14H29)2, formed using either a thermal deposition or a deposition from …

 
 
 
 
 
 

Birth and death of links control disease spreading in empirical contact networks

 
 

Petter Holme, Fredrik Liljeros

 
 

We investigate what structural aspects of a collection of twelve empirical temporal networks of human contacts are important to disease spreading. We scan the entire parameter …

 
 
 
 
 
 

Strong non-classical induction forces in ion-surface interactions: General origin of Hofmeister effects

 
 

Xinmin Liu, Hang Li, Rui Li et al.

 
 

Hofmeister effects continue to defy all-encompassing theories, and their origin is still a matter of debate. We observed strong Hofmeister effects in Ca2/Na exchange on a …

 
 
 
 
 
 

Relativistic Quantum Metrology: Exploiting relativity to improve quantum measurement technologies

 
 

Mehdi Ahmadi, David Edward Bruschi, Carlos Sabín et al.

 
 

We present a framework for relativistic quantum metrology that is useful for both Earth-based and space-based technologies. Quantum metrology has been so far successfully applied …

 
 
 
 
 
 

Untangling complex dynamical systems via derivative-variable correlations

 
 

Zoran Levnaji, Arkady Pikovsky

 
 

Inferring the internal interaction patterns of a complex dynamical system is a challenging problem. Traditional methods often rely on examining the correlations among the …

 
 
 
 
 
 

Direct observation of ionic structure at solid-liquid interfaces: a deep look into the Stern Layer

 
 

Igor Siretanu, Daniel Ebeling, Martin P. Andersson et al.

 
 

The distribution of ions and charge at solid-water interfaces plays an essential role in a wide range of processes in biology, geology and technology. While theoretical models of …

 
 
 
 
 
 

ERRATUM: Substrate-induced Band Gap Renormalization in Semiconducting Carbon Nanotubes

 
 

Nicholas A. Lanzillo, Neerav Kharche, Saroj K. Nayak

 
 

 
 
 
 
 
 

Role of the dispersion force in modeling the interfacial properties of molecule-metal interfaces: adsorption of thiophene on copper surfaces

 
 

Zhi-Xin Hu, Haiping Lan, Wei Ji

 
 

We present density functional theory calculations of the geometry, adsorption energy and electronic structure of thiophene adsorbed on Cu(111), Cu(110) and Cu(100) surfaces. Our …

 
 
 
 
 
 

Cohesiveness in Financial News and its Relation to Market Volatility

 
 

Matija Piškorec, Nino Antulov-Fantulin, Petra Kralj Novak et al.

 
 

Motivated by recent financial crises, significant research efforts have been put into studying contagion effects and herding behaviour in financial markets. Much less has been …

 
 
 
 
 
 

Brittle to Ductile Transition in Densified Silica Glass

 
 

Fenglin Yuan, Liping Huang

 
 

Current understanding of the brittleness of glass is limited by our poor understanding and control over the microscopic structure. In this study, we used a pressure quenching …

 
 
 
 
 
 

Strengthening of Graphene Aerogels with Tunable Density and High Adsorption Capacity towards Pb2+

 
 

Zhuo Han, Zhihong Tang, Shuling Shen et al.

 
 

Graphene aerogels (GAs) with high mechanical strength, tunable density and volume have been prepared only via soaking graphene hydrogels (GHs) in ammonia solution. The density and …

 
 
 
 
 
 

Phase-locking and Pulse Generation in Multi-Frequency Brillouin Oscillator via Four Wave Mixing

 
 

Thomas F. S. Büttner, Irina V. Kabakova, Darren D. Hudson et al.

 
 

There is an increasing demand for pulsed all-fibre lasers with gigahertz repetition rates for applications in telecommunications and metrology. The repetition rate of conventional …

 
 
 
 
 
 

Insights into transport velocity of colloid-associated plutonium relative to tritium in porous media

 
 

Jinchuan Xie, Jiachun Lu, Jianfeng Lin et al.

 
 

Although faster transport velocities of colloid-associated actinides, bacteria, and virus than nonreactive solutes have been observed in laboratory and field experiments, some …

 
 
 
 
 
 

Characterizing the effect of population heterogeneity on evolutionary dynamics on complex networks

 
 

Shaolin Tan, Jinhu Lü

 
 

Recently, the impact of network structure on evolutionary dynamics has been at the center of attention when studying the evolutionary process of structured populations. This paper …

 
 
 
 
 
 

Revealing Real-Time Emotional Responses: a Personalized Assessment based on Heartbeat Dynamics

 
 

Gaetano Valenza, Luca Citi, Antonio Lanatá et al.

 
 

Emotion recognition through computational modeling and analysis of physiological signals has been widely investigated in the last decade. Most of the proposed emotion recognition …

 
 
 
 
 
 

Kinetics of 90° domain wall motions and high frequency mesoscopic dielectric response in strained ferroelectrics: A phase-field simulation

 
 

P. Chu, D. P. Chen, Y. L. Wang et al.

 
 

The dielectric and ferroelectric behaviors of a ferroelectric are substantially determined by its domain structure and domain wall dynamics at mesoscopic level. A relationship …

 
 
 
 
 
 

Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings

 
 

Usawadee Sakulkhu, Morteza Mahmoudi, Lionel Maurizi et al.

 
 

Because of their biocompatibility and unique magnetic properties, superparamagnetic iron oxide nanoparticles NPs (SPIONs) are recognized as some of the most prominent agents for …

 
 
 
 
 
 

Subtractive 3D Printing of Optically Active Diamond Structures

 
 

Aiden A. Martin, Milos Toth, Igor Aharonovich

 
 

Controlled fabrication of semiconductor nanostructures is an essential step in engineering of high performance photonic and optoelectronic devices. Diamond in particular has …

 
 
 
 
 
 

Probing the Role of an Atomically Thin SiNx Interlayer on the Structure of Ultrathin Carbon Films

 
 

Neeraj Dwivedi, Ehsan Rismani-Yazdi, Reuben J. Yeo et al.

 
 

Filtered cathodic vacuum arc (FCVA) processed carbon films are being considered as a promising protective media overcoat material for future hard disk drives (HDDs). However, at …

 
 
 
 
 
 

PEG Molecular Net-Cloth Grafted on Polymeric Substrates and Its Bio-Merits

 
 

Changwen Zhao, Zhifeng Lin, Huabing Yin et al.

 
 

Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for the first time, we report a non-swelling …

 
 
 
 
 
 

Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization

 
 

Yan-Qing Guan, Zhe Zheng, Zheng Huang et al.

 
 

Nanomagnetic materials offer exciting avenues for advancing cancer therapies. Most researches have focused on efficient delivery of drugs in the body by incorporating various drug …

 
 
 
 
 
 

Modified surface plasmon polaritons for the nanoconcentration and long-range propagation of optical energy

 
 

Huawei Liang, Shuangchen Ruan, Min Zhang et al.

 
 

We propose a new surface plasmon polariton concept for the nanoconcentration and long-range propagation of optical energy. The propagation loss from the mode can be greatly …

 
 
 
 
 
 
 
Earth & Environmental Sciences top
 
 
 
 
 
 
 

Strong non-classical induction forces in ion-surface interactions: General origin of Hofmeister effects

 
 

Xinmin Liu, Hang Li, Rui Li et al.

 
 

Hofmeister effects continue to defy all-encompassing theories, and their origin is still a matter of debate. We observed strong Hofmeister effects in Ca2/Na exchange on a …

 
 
 
 
 
 

Jadeite in Chelyabinsk meteorite and the nature of an impact event on its parent body

 
 

Shin Ozawa, Masaaki Miyahara, Eiji Ohtani et al.

 
 

The Chelyabinsk asteroid impact is the second largest asteroid airburst in our recorded history. To prepare for a potential threat from asteroid impacts, it is important to …

 
 
 
 
 
 

Insights into transport velocity of colloid-associated plutonium relative to tritium in porous media

 
 

Jinchuan Xie, Jiachun Lu, Jianfeng Lin et al.

 
 

Although faster transport velocities of colloid-associated actinides, bacteria, and virus than nonreactive solutes have been observed in laboratory and field experiments, some …

 
 
 
 
 
 

Postglacial Fringing-Reef to Barrier-Reef conversion on Tahiti links Darwin's reef types

 
 

Paul Blanchon, Marian Granados-Corea, Elizabeth Abbey et al.

 
 

In 1842 Charles Darwin claimed that vertical growth on a subsiding foundation caused fringing reefs to transform into barrier reefs then atolls. Yet historically no transition …

 
 
 
 
 
 

A 1400-year terrigenous dust record on a coral island in South China Sea

 
 

Yi Liu, Liguang Sun, Xin Zhou et al.

 
 

We present analyses of a lacustrine sediment core (DY6) on Dongdao Island, which provides high-resolution paleoclimate records for the South China Sea (SCS). Results of element …

 
 
 
 
 
 
 
Health Sciences top
 
 
 
 
 
 
 

Diagnostic ability of %p2PSA and prostate health index for aggressive prostate cancer: a meta-analysis

 
 

Wenying Wang, Meilin Wang, Li Wang et al.

 
 

The role of [-2]proPSA (p2PSA) based diagnostic tests for the detection of aggressive prostate cancer (PCa) has not been fully evaluated. We conducted a meta-analysis to evaluate …

 
 
 
 
 
 

Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations

 
 

Graham K. Sheridan, Kumlesh K. Dev

 
 

Fingolimod (FTY720) is an oral therapy for relapsing remitting multiple sclerosis (MS) and targets sphingosine 1-phosphate receptors (S1PRs). FTY720 also rescues animals from …

 
 
 
 
 
 

Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies

 
 

Xinli LI, Jiuhong XU

 
 

Epidemiological studies support a protective role of lycopene against stroke occurrence or mortality, but the results have been conflicting. We conducted a meta-analysis to assess …

 
 
 
 
 
 

Auricular Acupressure Reduces Anxiety Levels and Improves Outcomes of in Vitro Fertilization: A Prospective, Randomized and Controlled Study

 
 

Fan Qu, Dan Zhang, Lu-Ting Chen et al.

 
 

The study was to explore whether auricular acupressure (AA) can relieve anxiety during the period from trans-vaginal oocyte retrieval to the embryo transfer in IVF treatment and …

 
 
 
 
 
 

Impaired Frontal-Basal Ganglia Connectivity in Adolescents with Internet Addiction

 
 

Baojuan Li, Karl J. Friston, Jian Liu et al.

 
 

Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study …

 
 
 
 
 
 

Peripheral blood miRNAs as a biomarker for chronic cardiovascular diseases

 
 

Yong Jiang, Hui-yan Wang, Hong-mei Cao et al.

 
 

Vascular diseases are the most prevalent diseases worldwide. This study intended to analyze peripheral blood miRNA levels and their correlation with NT-pro-BNP and cTN-I in …

 
 
 
 
 
 

Mapping Brain Injury with Symmetrical-channels' EEG Signal Analysis – A Pilot Study

 
 

LI Yi, LIU Xiao-ping, LING Xian-hong et al.

 
 

A technique for detecting brain injury at the bedside has great clinical value, but conventional imaging techniques (such as computed tomography [CT] and magnetic resonance …

 
 
 
 
 
 
 
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